HRP20130941T1 - Citratna sol 9e-15-(2-pirolidin-1-iletoksi)-7,12,25-trioksa-19,21,24-triazatetraciklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaena - Google Patents
Citratna sol 9e-15-(2-pirolidin-1-iletoksi)-7,12,25-trioksa-19,21,24-triazatetraciklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaena Download PDFInfo
- Publication number
- HRP20130941T1 HRP20130941T1 HRP20130941AT HRP20130941T HRP20130941T1 HR P20130941 T1 HRP20130941 T1 HR P20130941T1 HR P20130941A T HRP20130941A T HR P20130941AT HR P20130941 T HRP20130941 T HR P20130941T HR P20130941 T1 HRP20130941 T1 HR P20130941T1
- Authority
- HR
- Croatia
- Prior art keywords
- salt
- scale
- ray diffraction
- salt according
- triazatetracyclo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22560909P | 2009-07-15 | 2009-07-15 | |
| PCT/SG2010/000265 WO2011008172A1 (en) | 2009-07-15 | 2010-07-14 | 9e-15-(2-pyrrolidin-1-yl-ethoxy)-7,12,25-trioxa-19,21,24-triaza- tetracyclo[18.3.1.1(2,5).1(14)18)]hexacosa-1(24),2,4,9,14,16,18(26),20,22-nonaene citrate salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20130941T1 true HRP20130941T1 (hr) | 2013-11-08 |
Family
ID=42790728
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20130941AT HRP20130941T1 (hr) | 2009-07-15 | 2010-07-14 | Citratna sol 9e-15-(2-pirolidin-1-iletoksi)-7,12,25-trioksa-19,21,24-triazatetraciklo[18.3.1.1(2,5).1(14,18)]heksakoza-1(24),2,4,9,14,16,18(26),20,22-nonaena |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US9062074B2 (enExample) |
| EP (1) | EP2454266B1 (enExample) |
| JP (2) | JP6013911B2 (enExample) |
| CN (1) | CN102762577B (enExample) |
| AR (2) | AR077483A1 (enExample) |
| BR (1) | BR112012000750B1 (enExample) |
| CA (1) | CA2768210C (enExample) |
| DK (1) | DK2454266T3 (enExample) |
| ES (1) | ES2429525T3 (enExample) |
| HR (1) | HRP20130941T1 (enExample) |
| MX (1) | MX2012000680A (enExample) |
| PL (1) | PL2454266T3 (enExample) |
| PT (1) | PT2454266E (enExample) |
| RU (1) | RU2543721C2 (enExample) |
| SI (1) | SI2454266T1 (enExample) |
| SM (1) | SMT201300112B (enExample) |
| TW (1) | TWI537276B (enExample) |
| WO (1) | WO2011008172A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2966753A1 (en) | 2014-11-17 | 2016-05-26 | Arno Therapeutics, Inc. | Onapristone extended-release compositions and methods |
| AU2016326657B2 (en) | 2015-09-25 | 2019-10-24 | Context Biopharma, Inc. | Methods of making onapristone intermediates |
| CA3008422A1 (en) | 2015-12-15 | 2017-06-22 | Context Biopharma Inc. | Amorphous onapristone compositions and methods of making the same |
| US20180148471A1 (en) | 2016-11-30 | 2018-05-31 | Arno Therapeutics, Inc. | Methods for onapristone synthesis dehydration and deprotection |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY110603A (en) * | 1993-05-27 | 1998-08-29 | Novartis Ag | Tetrahydropyran derivatives |
| US7151096B2 (en) * | 2003-03-05 | 2006-12-19 | Irm Llc | Cyclic compounds and compositions as protein kinase inhibitors |
| CN101365703B (zh) * | 2005-11-16 | 2013-11-06 | S*Bio私人有限公司 | 杂烷基连接的嘧啶衍生物 |
-
2010
- 2010-07-14 EP EP10737645.1A patent/EP2454266B1/en active Active
- 2010-07-14 SI SI201030347T patent/SI2454266T1/sl unknown
- 2010-07-14 RU RU2012105044/04A patent/RU2543721C2/ru active
- 2010-07-14 PT PT107376451T patent/PT2454266E/pt unknown
- 2010-07-14 HR HRP20130941AT patent/HRP20130941T1/hr unknown
- 2010-07-14 BR BR112012000750-5A patent/BR112012000750B1/pt active IP Right Grant
- 2010-07-14 US US13/384,139 patent/US9062074B2/en active Active
- 2010-07-14 CN CN201080032627.5A patent/CN102762577B/zh active Active
- 2010-07-14 MX MX2012000680A patent/MX2012000680A/es active IP Right Grant
- 2010-07-14 PL PL10737645T patent/PL2454266T3/pl unknown
- 2010-07-14 ES ES10737645T patent/ES2429525T3/es active Active
- 2010-07-14 CA CA2768210A patent/CA2768210C/en active Active
- 2010-07-14 DK DK10737645.1T patent/DK2454266T3/da active
- 2010-07-14 JP JP2012520571A patent/JP6013911B2/ja active Active
- 2010-07-14 WO PCT/SG2010/000265 patent/WO2011008172A1/en not_active Ceased
- 2010-07-15 AR ARP100102594A patent/AR077483A1/es not_active Application Discontinuation
- 2010-07-15 TW TW099123331A patent/TWI537276B/zh active
-
2013
- 2013-10-04 SM SM201300112T patent/SMT201300112B/xx unknown
-
2015
- 2015-05-07 JP JP2015094972A patent/JP2015164941A/ja active Pending
-
2019
- 2019-08-05 AR ARP190102219A patent/AR114987A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN102762577A (zh) | 2012-10-31 |
| AR114987A2 (es) | 2020-11-11 |
| EP2454266A1 (en) | 2012-05-23 |
| JP2012533539A (ja) | 2012-12-27 |
| WO2011008172A1 (en) | 2011-01-20 |
| CA2768210C (en) | 2017-08-15 |
| ES2429525T3 (es) | 2013-11-15 |
| PL2454266T3 (pl) | 2014-01-31 |
| AR077483A1 (es) | 2011-08-31 |
| MX2012000680A (es) | 2012-02-28 |
| BR112012000750A8 (pt) | 2018-02-06 |
| TWI537276B (zh) | 2016-06-11 |
| EP2454266B1 (en) | 2013-07-10 |
| CA2768210A1 (en) | 2011-01-20 |
| SI2454266T1 (sl) | 2013-10-30 |
| BR112012000750B1 (pt) | 2021-05-25 |
| BR112012000750A2 (pt) | 2016-08-09 |
| SMT201300112B (it) | 2013-11-08 |
| JP2015164941A (ja) | 2015-09-17 |
| US9062074B2 (en) | 2015-06-23 |
| RU2012105044A (ru) | 2013-08-20 |
| HK1178159A1 (en) | 2013-09-06 |
| DK2454266T3 (da) | 2013-09-08 |
| TW201107336A (en) | 2011-03-01 |
| US20120196876A1 (en) | 2012-08-02 |
| RU2543721C2 (ru) | 2015-03-10 |
| JP6013911B2 (ja) | 2016-10-25 |
| CN102762577B (zh) | 2015-01-07 |
| PT2454266E (pt) | 2013-10-10 |
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