SI2177536T1 - Protitelesa proti amiloidnemu peptidu beta - Google Patents

Protitelesa proti amiloidnemu peptidu beta

Info

Publication number
SI2177536T1
SI2177536T1 SI200731503T SI200731503T SI2177536T1 SI 2177536 T1 SI2177536 T1 SI 2177536T1 SI 200731503 T SI200731503 T SI 200731503T SI 200731503 T SI200731503 T SI 200731503T SI 2177536 T1 SI2177536 T1 SI 2177536T1
Authority
SI
Slovenia
Prior art keywords
antibodies against
beta peptide
against amyloid
amyloid
peptide
Prior art date
Application number
SI200731503T
Other languages
English (en)
Inventor
Stephen Anthony Burbidge
Jonathan Henry Ellis
Susannah K. Ford
Volker Germaschewski
Umesh Kumar
Karen Louise Philpott
Peter Ernest Soden
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of SI2177536T1 publication Critical patent/SI2177536T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71—Decreased effector function due to an Fc-modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
SI200731503T 2006-03-30 2007-03-27 Protitelesa proti amiloidnemu peptidu beta SI2177536T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78758806P 2006-03-30 2006-03-30
EP09178407.4A EP2177536B1 (en) 2006-03-30 2007-03-27 Antibodies against amyloid-beta peptide

Publications (1)

Publication Number Publication Date
SI2177536T1 true SI2177536T1 (sl) 2014-09-30

Family

ID=38284050

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200731503T SI2177536T1 (sl) 2006-03-30 2007-03-27 Protitelesa proti amiloidnemu peptidu beta
SI200730173T SI1996621T1 (sl) 2006-03-30 2007-03-27 Protitelesa proti amiloidnemu peptidu beta

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200730173T SI1996621T1 (sl) 2006-03-30 2007-03-27 Protitelesa proti amiloidnemu peptidu beta

Country Status (33)

Country Link
US (3) US8227576B2 (sl)
EP (2) EP2177536B1 (sl)
JP (1) JP5103466B2 (sl)
KR (2) KR20120093400A (sl)
CN (2) CN101415729B (sl)
AR (1) AR060332A1 (sl)
AT (1) ATE451392T1 (sl)
AU (1) AU2007233831B2 (sl)
BR (1) BRPI0709246A2 (sl)
CA (1) CA2647808C (sl)
CR (1) CR10347A (sl)
CY (1) CY1109877T1 (sl)
DE (1) DE602007003703D1 (sl)
DK (2) DK2177536T3 (sl)
EA (1) EA015654B9 (sl)
ES (2) ES2338179T3 (sl)
HK (2) HK1138015A1 (sl)
HR (2) HRP20100115T1 (sl)
IL (1) IL193695A (sl)
JO (1) JO2576B1 (sl)
MA (1) MA30337B1 (sl)
MX (1) MX2008012483A (sl)
MY (1) MY149630A (sl)
NO (1) NO20083793L (sl)
NZ (1) NZ571038A (sl)
PE (1) PE20080181A1 (sl)
PL (2) PL2177536T3 (sl)
PT (2) PT1996621E (sl)
SI (2) SI2177536T1 (sl)
TW (1) TWI385179B (sl)
UA (1) UA94734C2 (sl)
WO (1) WO2007113172A2 (sl)
ZA (1) ZA200807911B (sl)

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EP2308897A1 (en) * 2009-10-09 2011-04-13 Pierre Fabre Medicament Chimeric antibodies specific for CD151 and use thereof in the treatment of cancer
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CA2826286C (en) 2011-01-31 2021-09-21 Intellect Neurosciences Inc. Treatment of tauopathies
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CN104558172A (zh) * 2015-01-04 2015-04-29 东南大学 一种针对β淀粉样蛋白的单域重链纳米抗体及其应用
CN107921143B (zh) 2015-06-15 2021-11-19 安吉奥开米公司 用于治疗软脑膜癌病的方法
JP7002446B2 (ja) 2015-09-21 2022-03-04 アプティーボ リサーチ アンド デベロップメント エルエルシー Ｃｄ３結合ポリペプチド
WO2017072090A1 (en) * 2015-10-27 2017-05-04 Glaxosmithkline Intellectual Property Development Limited Combination therapy
EP3624842A4 (en) * 2017-06-29 2021-04-07 The Trustees Of Columbia University In The City Of New York CHIMERA ANTIBODIES FOR TREATMENT OF AMYLOID DEPOSITION DISEASES
US11382974B2 (en) 2017-08-01 2022-07-12 The Trustees Of Columbia University In The City Of New York Methods and compositions for treatment of amyloid deposition diseases
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JP2023535024A (ja) 2020-07-23 2023-08-15 オター プロシーナ リミテッド 抗ａベータ抗体
TW202300517A (zh) 2021-03-12 2023-01-01 美商美國禮來大藥廠 抗類澱粉β抗體及其用途
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Also Published As

Publication number Publication date
NO20083793L (no) 2008-10-13
SI1996621T1 (sl) 2010-04-30
CY1109877T1 (el) 2014-09-10
CN103539857A (zh) 2014-01-29
JP2009531380A (ja) 2009-09-03
US9193784B2 (en) 2015-11-24
PE20080181A1 (es) 2008-03-16
PT1996621E (pt) 2010-03-08
EA015654B1 (ru) 2011-10-31
ES2338179T3 (es) 2010-05-04
EP2177536A1 (en) 2010-04-21
KR20120093400A (ko) 2012-08-22
JO2576B1 (en) 2011-02-27
EP1996621B1 (en) 2009-12-09
WO2007113172A2 (en) 2007-10-11
EA200801842A1 (ru) 2009-02-27
MY149630A (en) 2013-09-13
PT2177536E (pt) 2014-08-22
AU2007233831B2 (en) 2013-02-14
EP1996621A2 (en) 2008-12-03
ES2484967T3 (es) 2014-08-12
US20140050719A1 (en) 2014-02-20
AU2007233831A1 (en) 2007-10-11
US20160024197A1 (en) 2016-01-28
CR10347A (es) 2008-10-29
US20110142824A1 (en) 2011-06-16
WO2007113172A3 (en) 2007-11-29
HK1138015A1 (en) 2010-08-13
TWI385179B (zh) 2013-02-11
HRP20140618T1 (hr) 2014-08-15
IL193695A0 (en) 2011-08-01
MX2008012483A (es) 2008-10-10
DK2177536T3 (da) 2014-07-14
NZ571038A (en) 2011-03-31
DK1996621T3 (da) 2010-04-19
EP2177536B1 (en) 2014-06-04
BRPI0709246A2 (pt) 2011-07-12
JP5103466B2 (ja) 2012-12-19
UA94734C2 (ru) 2011-06-10
CN101415729B (zh) 2013-09-04
MA30337B1 (fr) 2009-04-01
TW200815466A (en) 2008-04-01
DE602007003703D1 (de) 2010-01-21
HRP20100115T1 (hr) 2010-04-30
KR101263294B1 (ko) 2013-06-04
ATE451392T1 (de) 2009-12-15
EA015654B9 (ru) 2012-01-30
AR060332A1 (es) 2008-06-11
KR20080113273A (ko) 2008-12-29
CA2647808C (en) 2015-11-17
HK1122311A1 (en) 2009-05-15
PL1996621T3 (pl) 2010-05-31
IL193695A (en) 2012-05-31
CA2647808A1 (en) 2007-10-11
ZA200807911B (en) 2009-11-25
CN101415729A (zh) 2009-04-22
US8227576B2 (en) 2012-07-24
PL2177536T3 (pl) 2014-11-28

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