SI21506A - Postopek za pripravo perindoprila - Google Patents

Postopek za pripravo perindoprila Download PDF

Info

Publication number
SI21506A
SI21506A SI200300118A SI200300118A SI21506A SI 21506 A SI21506 A SI 21506A SI 200300118 A SI200300118 A SI 200300118A SI 200300118 A SI200300118 A SI 200300118A SI 21506 A SI21506 A SI 21506A
Authority
SI
Slovenia
Prior art keywords
perindopril
group
formula
butyl
synthesis
Prior art date
Application number
SI200300118A
Other languages
English (en)
Slovenian (sl)
Inventor
Rudolf Ru�man
Original Assignee
LEK farmacevtska dru�ba d.d.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LEK farmacevtska dru�ba d.d. filed Critical LEK farmacevtska dru�ba d.d.
Priority to SI200300118A priority Critical patent/SI21506A/sl
Priority to EP04731809A priority patent/EP1628995B1/de
Priority to DE602004007265T priority patent/DE602004007265T2/de
Priority to ES04731809T priority patent/ES2287725T3/es
Priority to PL04731809T priority patent/PL1628995T3/pl
Priority to US10/555,848 priority patent/US20070173637A1/en
Priority to SI200430444T priority patent/SI1628995T1/sl
Priority to PCT/SI2004/000020 priority patent/WO2004099236A1/en
Priority to AT04731809T priority patent/ATE365745T1/de
Priority to RU2005138050/04A priority patent/RU2363695C2/ru
Publication of SI21506A publication Critical patent/SI21506A/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
SI200300118A 2003-05-08 2003-05-08 Postopek za pripravo perindoprila SI21506A (sl)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SI200300118A SI21506A (sl) 2003-05-08 2003-05-08 Postopek za pripravo perindoprila
EP04731809A EP1628995B1 (de) 2003-05-08 2004-05-07 Verfahren zur herstellung von perindopril unter verwendung von tetramethyluroniumsalzen als kopplungsreagenzien
DE602004007265T DE602004007265T2 (de) 2003-05-08 2004-05-07 Verfahren zur herstellung von perindopril unter verwendung von tetramethyluroniumsalzen als kopplungsreagenzien
ES04731809T ES2287725T3 (es) 2003-05-08 2004-05-07 Un proceso para la preparacion de perindopril utilizando las sales de tetrametiluronio como reactivos de acoplamiento.
PL04731809T PL1628995T3 (pl) 2003-05-08 2004-05-07 Sposób wytwarzania perindoprilu przy wykorzystaniu soli tetrametylouroniowych jako reagentów sprzęgających
US10/555,848 US20070173637A1 (en) 2003-05-08 2004-05-07 Process for the preparation of perindopril using tetramethyluronium salts as coupling reagents
SI200430444T SI1628995T1 (sl) 2003-05-08 2004-05-07 Postopek za pripravo perindoprila z uporabo tetrametiluronijevih soli kot reagenta za pripajanje
PCT/SI2004/000020 WO2004099236A1 (en) 2003-05-08 2004-05-07 A process for the preparation of perindopril using tetramethyluronium salts as coupling reagents
AT04731809T ATE365745T1 (de) 2003-05-08 2004-05-07 Verfahren zur herstellung von perindopril unter verwendung von tetramethyluroniumsalzen als kopplungsreagenzien
RU2005138050/04A RU2363695C2 (ru) 2003-05-08 2004-05-07 Способ получения периндоприла с использованием тетраметилурониевых солей в качестве реагентов реакции сочетания

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SI200300118A SI21506A (sl) 2003-05-08 2003-05-08 Postopek za pripravo perindoprila

Publications (1)

Publication Number Publication Date
SI21506A true SI21506A (sl) 2004-12-31

Family

ID=33434252

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200300118A SI21506A (sl) 2003-05-08 2003-05-08 Postopek za pripravo perindoprila
SI200430444T SI1628995T1 (sl) 2003-05-08 2004-05-07 Postopek za pripravo perindoprila z uporabo tetrametiluronijevih soli kot reagenta za pripajanje

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200430444T SI1628995T1 (sl) 2003-05-08 2004-05-07 Postopek za pripravo perindoprila z uporabo tetrametiluronijevih soli kot reagenta za pripajanje

Country Status (9)

Country Link
US (1) US20070173637A1 (de)
EP (1) EP1628995B1 (de)
AT (1) ATE365745T1 (de)
DE (1) DE602004007265T2 (de)
ES (1) ES2287725T3 (de)
PL (1) PL1628995T3 (de)
RU (1) RU2363695C2 (de)
SI (2) SI21506A (de)
WO (1) WO2004099236A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI21703A (en) * 2004-01-14 2005-08-31 Lek Farmacevtska Druzba Dd Inclusion complexes of perindopril, procedure of their preparation, pharmaceutical compositions containing these complexes and their application in treatment of hypertensia
CN111116709B (zh) * 2019-12-31 2022-06-24 北京鑫开元医药科技有限公司 一种培哚普利制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002094857A1 (en) * 2001-05-23 2002-11-28 The Curators Of The University Of Missouri Inverse solid phase synthesis of peptides
AR036187A1 (es) * 2001-07-24 2004-08-18 Adir Un proceso para la preparacion de perindopril, compuestos analogos y sus sales, compuesto intermediario 2,5-dioxo-oxazolidina y proceso para preparar un intermediario

Also Published As

Publication number Publication date
EP1628995B1 (de) 2007-06-27
SI1628995T1 (sl) 2007-12-31
ES2287725T3 (es) 2007-12-16
RU2005138050A (ru) 2006-08-10
WO2004099236A1 (en) 2004-11-18
ATE365745T1 (de) 2007-07-15
DE602004007265D1 (de) 2007-08-09
DE602004007265T2 (de) 2008-02-28
EP1628995A1 (de) 2006-03-01
PL1628995T3 (pl) 2007-11-30
RU2363695C2 (ru) 2009-08-10
US20070173637A1 (en) 2007-07-26

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OO00 Grant of patent

Effective date: 20040303

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Effective date: 20101213