SI21223A - Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom - Google Patents
Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom Download PDFInfo
- Publication number
- SI21223A SI21223A SI200200155A SI200200155A SI21223A SI 21223 A SI21223 A SI 21223A SI 200200155 A SI200200155 A SI 200200155A SI 200200155 A SI200200155 A SI 200200155A SI 21223 A SI21223 A SI 21223A
- Authority
- SI
- Slovenia
- Prior art keywords
- donepezil
- pharmaceutically acceptable
- donepezil hydrochloride
- pharmaceutical formulation
- mixture
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicinal Preparation (AREA)
Priority Applications (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200200155A SI21223A (sl) | 2002-06-19 | 2002-06-19 | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
EP03741747A EP1513528B1 (en) | 2002-06-19 | 2003-06-18 | Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride |
PT03741747T PT1513528E (pt) | 2002-06-19 | 2003-06-18 | Composição farmacêutica contendo forma amorfa estabilizada de cloridrato de donepezilo |
UAA200500514A UA86573C2 (ru) | 2002-06-19 | 2003-06-18 | Фармацевтическая композиция, которая содержит стабилизированную аморфную форму донепезила гидрохлорида |
EA200500040A EA012904B1 (ru) | 2002-06-19 | 2003-06-18 | Фармацевтическая композиция, содержащая стабилизированную аморфную форму донепезил гидрохлорида |
SI200331643T SI1513528T1 (sl) | 2002-06-19 | 2003-06-18 | Farmacevtski sestavek, ki vsebuje stabilizirano amorfno obliko donepezilijevega hidroklorida |
YU110604A RS51824B (en) | 2002-06-19 | 2003-06-18 | PHARMACEUTICAL FORMULATION WITH STABILIZED AMORPHIC FORM OF DONEPESIL HYDROCHLORIDE |
DK03741747T DK1513528T3 (da) | 2002-06-19 | 2003-06-18 | Farmaceutisk sammens tning indeholdende stabiliserede amorfe former af donepezilhydrochlorid |
ES03741747T ES2326529T3 (es) | 2002-06-19 | 2003-06-18 | Composicion farmaceutica que contiene una forma amorfa estabilizada de clorhidrato de donepezil. |
PCT/SI2003/000019 WO2004000317A1 (en) | 2002-06-19 | 2003-06-18 | Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride |
AU2003279102A AU2003279102A1 (en) | 2002-06-19 | 2003-06-18 | Pharmaceutical composition containing stabilised amorphous form of donepezil hydrochloride |
DE60327696T DE60327696D1 (de) | 2002-06-19 | 2003-06-18 | Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid |
PL372116A PL212584B1 (pl) | 2002-06-19 | 2003-06-18 | Kompozycja farmaceutyczna zawierajaca chlorowodorek donepezilu w bezpostaciowej formie i sposób jej wytwarzania, sposób wytwarzania bezpostaciowej formy chlorowodorku donepezilu i jego zastosowanie |
AT03741747T ATE431739T1 (de) | 2002-06-19 | 2003-06-18 | Pharmazeutische zusammensetzung enthaltend stabilisierte amorphe form von donepezil hydrochlorid |
HRP20041198AA HRP20041198B1 (hr) | 2002-06-19 | 2004-12-17 | Farmaceutski pripravci koji sadrže stabiliziranu amorfnu formu donepezil hidroklorida |
CY20091100878T CY1109314T1 (el) | 2002-06-19 | 2009-08-17 | Φαρμακευτικη συνθεση περιεχουσα σταθεροποιημενη αμορφη μορφη της υδροχλωρικης ντονεπεζιλης |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SI200200155A SI21223A (sl) | 2002-06-19 | 2002-06-19 | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
Publications (1)
Publication Number | Publication Date |
---|---|
SI21223A true SI21223A (sl) | 2003-12-31 |
Family
ID=29778199
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200200155A SI21223A (sl) | 2002-06-19 | 2002-06-19 | Farmacevtska formulacija s stabiliziranim amorfnim donepezilijevim kloridom |
SI200331643T SI1513528T1 (sl) | 2002-06-19 | 2003-06-18 | Farmacevtski sestavek, ki vsebuje stabilizirano amorfno obliko donepezilijevega hidroklorida |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200331643T SI1513528T1 (sl) | 2002-06-19 | 2003-06-18 | Farmacevtski sestavek, ki vsebuje stabilizirano amorfno obliko donepezilijevega hidroklorida |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1513528B1 (el) |
AT (1) | ATE431739T1 (el) |
AU (1) | AU2003279102A1 (el) |
CY (1) | CY1109314T1 (el) |
DE (1) | DE60327696D1 (el) |
DK (1) | DK1513528T3 (el) |
EA (1) | EA012904B1 (el) |
ES (1) | ES2326529T3 (el) |
HR (1) | HRP20041198B1 (el) |
PL (1) | PL212584B1 (el) |
PT (1) | PT1513528E (el) |
RS (1) | RS51824B (el) |
SI (2) | SI21223A (el) |
UA (1) | UA86573C2 (el) |
WO (1) | WO2004000317A1 (el) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL150509A (en) | 2002-07-01 | 2007-07-04 | Joseph Kaspi | Pharmaceutical preparations containing donafazil hydrochloride |
IL154370A0 (en) * | 2003-02-10 | 2003-09-17 | Chemagis Ltd | Solid amorphous mixtures, processes for the preparation thereof and pharmaceutical compositions containing the same |
WO2005065645A2 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Donepezil formulations |
US8980894B2 (en) | 2004-03-25 | 2015-03-17 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure |
EP1579862A1 (en) | 2004-03-25 | 2005-09-28 | Boehringer Ingelheim Vetmedica Gmbh | Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure |
IL171137A (en) | 2004-09-29 | 2012-01-31 | Chemagis Ltd | Use of purified malt donfazil for the preparation of pure pharmaceutical amorphous donfazil hydrochloride |
DE602005011326D1 (de) * | 2004-10-19 | 2009-01-08 | Krka Tovarna Zdravil D D | Feste pharmazeutische zusammensetzung mit donepezilhydrochlorid |
WO2006063025A1 (en) * | 2004-12-07 | 2006-06-15 | Nektar Therapeutics | Stable non-crystalline formulation comprising donepezil |
US20060122226A1 (en) | 2004-12-08 | 2006-06-08 | Itai Adin | Crystalline forms of Donepezil base |
EP1830886B1 (en) | 2004-12-27 | 2016-04-13 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
JP2007015934A (ja) * | 2005-07-05 | 2007-01-25 | Meiko Shoji Kk | 温感クリーム化粧料 |
DE102005060377A1 (de) | 2005-12-16 | 2007-06-21 | Ratiopharm Gmbh | Pharmazeutische Zusammensetzung enthaltend Donepezilhydrochlorid, Tablette hieraus und Verfahren zu deren Herstellung |
EP1920785A1 (en) | 2006-11-07 | 2008-05-14 | Boehringer Ingelheim Vetmedica Gmbh | Liquid preparation comprising a complex of pimobendan and cyclodextrin |
DE102007037932A1 (de) | 2007-08-11 | 2009-02-12 | Alfred E. Tiefenbacher Gmbh & Co.Kg | Donepezilhydrochlorid in amorpher Form enthaltende Tablette |
DE102009041839A1 (de) * | 2009-09-18 | 2011-03-24 | Dolorgiet Gmbh & Co. Kg | Donepezil-haltige Tabletten |
EP2366378A1 (en) * | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
WO2011151359A1 (en) | 2010-06-02 | 2011-12-08 | Noscira, S.A. | Combined treatment with a cholinesterase inhibitor and a thiadiazolidinedione derivative |
EP2502620A1 (en) | 2011-03-24 | 2012-09-26 | Krka Tovarna Zdravil, D.D., Novo Mesto | Solid pharmaceutical composition comprising donepezil |
US10398705B2 (en) | 2012-03-15 | 2019-09-03 | Boehringer Ingelheim Vetmedica Gmbh | Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof |
CN105377235A (zh) | 2013-07-19 | 2016-03-02 | 勃林格殷格翰动物保健有限公司 | 含有防腐的醚化的环糊精衍生物的液体水性药物组合物 |
CA3176466A1 (en) | 2013-12-04 | 2015-06-11 | Boehringer Ingelheim Vetmedica Gmbh | Improved pharmaceutical compositions of pimobendan |
WO2017091373A1 (en) * | 2015-11-25 | 2017-06-01 | Patheon Development Services Inc. | Amorphous dispersion granules and oral dosage forms |
US10537570B2 (en) | 2016-04-06 | 2020-01-21 | Boehringer Ingelheim Vetmedica Gmbh | Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease |
KR102372630B1 (ko) * | 2019-05-15 | 2022-03-14 | 주식회사 대웅제약 | 고함량의 도네페질 또는 그의 염을 포함하는 경피흡수제제 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2525108B1 (fr) * | 1982-04-19 | 1989-05-12 | Elan Corp Ltd | Medicaments a haut degre de solubilite et procede pour leur obtention |
EP1019374B1 (en) * | 1996-06-07 | 2003-01-02 | Eisai Co., Ltd. | Polymorphs of donepezil hydrochloride and process for production |
ATE404178T1 (de) * | 1999-02-10 | 2008-08-15 | Pfizer Prod Inc | Vorrichtung mit matrixgesteuerter wirkstofffreisetzung |
ATE329579T1 (de) * | 1999-11-12 | 2006-07-15 | Abbott Lab | Feste dispersion mit ritonavir, fenofibrat oder griseofulvin |
-
2002
- 2002-06-19 SI SI200200155A patent/SI21223A/sl not_active IP Right Cessation
-
2003
- 2003-06-18 EP EP03741747A patent/EP1513528B1/en not_active Expired - Lifetime
- 2003-06-18 WO PCT/SI2003/000019 patent/WO2004000317A1/en not_active Application Discontinuation
- 2003-06-18 PT PT03741747T patent/PT1513528E/pt unknown
- 2003-06-18 PL PL372116A patent/PL212584B1/pl unknown
- 2003-06-18 SI SI200331643T patent/SI1513528T1/sl unknown
- 2003-06-18 DK DK03741747T patent/DK1513528T3/da active
- 2003-06-18 UA UAA200500514A patent/UA86573C2/ru unknown
- 2003-06-18 AT AT03741747T patent/ATE431739T1/de active
- 2003-06-18 RS YU110604A patent/RS51824B/en unknown
- 2003-06-18 AU AU2003279102A patent/AU2003279102A1/en not_active Abandoned
- 2003-06-18 EA EA200500040A patent/EA012904B1/ru not_active IP Right Cessation
- 2003-06-18 ES ES03741747T patent/ES2326529T3/es not_active Expired - Lifetime
- 2003-06-18 DE DE60327696T patent/DE60327696D1/de not_active Expired - Lifetime
-
2004
- 2004-12-17 HR HRP20041198AA patent/HRP20041198B1/hr not_active IP Right Cessation
-
2009
- 2009-08-17 CY CY20091100878T patent/CY1109314T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
WO2004000317A1 (en) | 2003-12-31 |
ES2326529T3 (es) | 2009-10-14 |
SI1513528T1 (sl) | 2009-10-31 |
PT1513528E (pt) | 2009-08-18 |
PL212584B1 (pl) | 2012-10-31 |
EP1513528A1 (en) | 2005-03-16 |
ATE431739T1 (de) | 2009-06-15 |
RS51824B (en) | 2012-02-29 |
DE60327696D1 (de) | 2009-07-02 |
PL372116A1 (en) | 2005-07-11 |
EA012904B1 (ru) | 2010-02-26 |
DK1513528T3 (da) | 2009-09-07 |
EA200500040A1 (ru) | 2005-06-30 |
RS110604A (en) | 2007-02-05 |
HRP20041198A2 (en) | 2005-04-30 |
EP1513528B1 (en) | 2009-05-20 |
UA86573C2 (ru) | 2009-05-12 |
AU2003279102A1 (en) | 2004-01-06 |
HRP20041198B1 (hr) | 2013-05-31 |
CY1109314T1 (el) | 2014-07-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
IF | Valid on the event date | ||
KO00 | Lapse of patent |
Effective date: 20120704 |