SI1899350T1 - Derivati pirazolo d azepina kot antagonisti histamina h - Google Patents
Derivati pirazolo d azepina kot antagonisti histamina hInfo
- Publication number
- SI1899350T1 SI1899350T1 SI200630733T SI200630733T SI1899350T1 SI 1899350 T1 SI1899350 T1 SI 1899350T1 SI 200630733 T SI200630733 T SI 200630733T SI 200630733 T SI200630733 T SI 200630733T SI 1899350 T1 SI1899350 T1 SI 1899350T1
- Authority
- SI
- Slovenia
- Prior art keywords
- antagonists
- derivatives
- åazepine
- pyrazolo
- histamine
- Prior art date
Links
- 239000003395 histamine H3 receptor antagonist Substances 0.000 title 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000926 neurological effect Effects 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 208000020016 psychiatric disease Diseases 0.000 abstract 1
- 150000003217 pyrazoles Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0513886.2A GB0513886D0 (en) | 2005-07-06 | 2005-07-06 | Novel compounds |
| PCT/EP2006/006613 WO2007025596A1 (en) | 2005-07-06 | 2006-07-04 | Pyrazolo [3 , 4-d] azepine derivatives as histamine h3 antagonists |
| EP06818218A EP1899350B1 (en) | 2005-07-06 | 2006-07-04 | Pyrazolo [3 , 4-d]azepine derivatives as histamine h3 antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1899350T1 true SI1899350T1 (sl) | 2010-09-30 |
Family
ID=34856781
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200630733T SI1899350T1 (sl) | 2005-07-06 | 2006-07-04 | Derivati pirazolo d azepina kot antagonisti histamina h |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US7888347B2 (https=) |
| EP (1) | EP1899350B1 (https=) |
| JP (1) | JP5145218B2 (https=) |
| KR (1) | KR20080037651A (https=) |
| CN (1) | CN101258154B (https=) |
| AT (1) | ATE467636T1 (https=) |
| AU (1) | AU2006286897A1 (https=) |
| BR (1) | BRPI0612719A2 (https=) |
| CA (1) | CA2614232A1 (https=) |
| CR (1) | CR9622A (https=) |
| CY (1) | CY1110711T1 (https=) |
| DE (1) | DE602006014273D1 (https=) |
| DK (1) | DK1899350T3 (https=) |
| EA (1) | EA013600B1 (https=) |
| ES (1) | ES2345841T3 (https=) |
| GB (1) | GB0513886D0 (https=) |
| HR (1) | HRP20100401T1 (https=) |
| IL (1) | IL188184A0 (https=) |
| MA (1) | MA29623B1 (https=) |
| MX (1) | MX2008000383A (https=) |
| NO (1) | NO20080563L (https=) |
| PL (1) | PL1899350T3 (https=) |
| PT (1) | PT1899350E (https=) |
| SI (1) | SI1899350T1 (https=) |
| UA (1) | UA93047C2 (https=) |
| WO (1) | WO2007025596A1 (https=) |
| ZA (1) | ZA200710798B (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103382174A (zh) | 2006-06-23 | 2013-11-06 | 雅培制药有限公司 | 作为组胺h3受体调节物的环丙胺衍生物 |
| US9108948B2 (en) | 2006-06-23 | 2015-08-18 | Abbvie Inc. | Cyclopropyl amine derivatives |
| KR20100059919A (ko) | 2007-09-24 | 2010-06-04 | 코멘티스, 인코포레이티드 | 치료를 위한 베타-세크레타제 억제제로서 (3-히드록시-4-아미노-부탄-2일)-3-(2-티아졸-2-일-피롤리딘-1-카르보닐) 벤즈아미드 유도체 및 관련 화합물 |
| US9186353B2 (en) * | 2009-04-27 | 2015-11-17 | Abbvie Inc. | Treatment of osteoarthritis pain |
| US8853390B2 (en) | 2010-09-16 | 2014-10-07 | Abbvie Inc. | Processes for preparing 1,2-substituted cyclopropyl derivatives |
| CN102952139B (zh) * | 2011-08-30 | 2016-08-10 | 上海药明康德新药开发有限公司 | 反式-3a-氟吡咯烷[3,4-C]并环化合物及其制备方法 |
| WO2013151982A1 (en) | 2012-04-03 | 2013-10-10 | Arena Pharmaceuticals, Inc. | Methods and compounds useful in treating pruritus, and methods for identifying such compounds |
| EP2647377A1 (en) | 2012-04-06 | 2013-10-09 | Sanofi | Use of an h3 receptor antagonist for the treatment of alzheimer's disease |
| JO3407B1 (ar) | 2012-05-31 | 2019-10-20 | Eisai R&D Man Co Ltd | مركبات رباعي هيدرو بيرازولو بيريميدين |
| US9910887B2 (en) * | 2013-04-25 | 2018-03-06 | Facebook, Inc. | Variable search query vertical access |
| MX2018014034A (es) * | 2016-05-25 | 2019-08-29 | Akarna Therapeutics Ltd | Compuestos bicíclicos fusionados para el tratamiento de enfermedades. |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU6018799A (en) * | 1998-09-09 | 2000-03-27 | Ishihara Sangyo Kaisha Ltd. | Fused-benzene derivatives useful as herbicides |
| JP2002542245A (ja) * | 1999-04-16 | 2002-12-10 | ノボ ノルディスク アクティーゼルスカブ | 置換イミダゾール、それらの製造および使用 |
| JP2001220390A (ja) | 2000-02-09 | 2001-08-14 | Yamanouchi Pharmaceut Co Ltd | 縮合ピラゾール誘導体 |
| ES2283768T3 (es) * | 2002-06-06 | 2007-11-01 | Novo Nordisk A/S | Hexahidropirrolo(1,2-a)piracinas, octahidropirido(1,2-a)piracinas y decahidropiracino(1,2-a)acepinas sustituidas. |
| US6770597B2 (en) | 2002-07-17 | 2004-08-03 | Ishihara Sangyo Kaisha, Ltd. | Benzohydrazide derivatives as herbicides and desiccant compositions containing them |
| JP2005537290A (ja) | 2002-07-25 | 2005-12-08 | ファルマシア・イタリア・エス・ピー・エー | キナーゼ阻害剤として活性なビシクロピラゾール類、その製造方法、およびそれを含有する薬学的組成物 |
| EP1539704A1 (en) * | 2002-08-20 | 2005-06-15 | Eli Lilly And Company | Substituted azepines as histamine h3 receptor antagonists, preparation and therapeutic uses |
| GB0224083D0 (en) | 2002-10-16 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
| GB0224557D0 (en) | 2002-10-22 | 2002-11-27 | Glaxo Group Ltd | Novel compounds |
| EP2133340B1 (en) | 2002-12-20 | 2013-01-16 | Glaxo Group Limited | Novel benzazepine derivatives |
| SI1668014T1 (sl) * | 2003-09-17 | 2009-06-30 | Janssen Pharmaceutica Nv | Kondenzirane heterociklične spojine kot modulatorji serotoninskih receptorjev |
| GB0329214D0 (en) | 2003-12-17 | 2004-01-21 | Glaxo Group Ltd | Novel compounds |
| GB0405628D0 (en) | 2004-03-12 | 2004-04-21 | Glaxo Group Ltd | Novel compounds |
| GB0408083D0 (en) | 2004-04-08 | 2004-05-12 | Glaxo Group Ltd | Novel compounds |
| WO2005123723A1 (en) | 2004-06-18 | 2005-12-29 | Glaxo Group Limited | 3-cycloalkylbenzazepines as histamine h3 antagonists |
| GB0418267D0 (en) | 2004-08-16 | 2004-09-15 | Glaxo Group Ltd | Novel compounds |
| RU2007125648A (ru) | 2004-12-07 | 2009-01-20 | Глэксо Груп Лимитед (GB) | Инденильные производные и их применение для лечения неврологических расстройств |
| US20080161289A1 (en) | 2005-03-14 | 2008-07-03 | Glaxo Group Limited | Fused Thiazole Derivatives Having Affinity for the Histamine H3 Receptor |
-
2005
- 2005-07-06 GB GBGB0513886.2A patent/GB0513886D0/en not_active Ceased
-
2006
- 2006-07-04 JP JP2008519862A patent/JP5145218B2/ja not_active Expired - Fee Related
- 2006-07-04 HR HR20100401T patent/HRP20100401T1/hr unknown
- 2006-07-04 AU AU2006286897A patent/AU2006286897A1/en not_active Abandoned
- 2006-07-04 AT AT06818218T patent/ATE467636T1/de active
- 2006-07-04 BR BRPI0612719-3A patent/BRPI0612719A2/pt not_active IP Right Cessation
- 2006-07-04 ES ES06818218T patent/ES2345841T3/es active Active
- 2006-07-04 PL PL06818218T patent/PL1899350T3/pl unknown
- 2006-07-04 EP EP06818218A patent/EP1899350B1/en not_active Not-in-force
- 2006-07-04 US US11/994,689 patent/US7888347B2/en not_active Expired - Fee Related
- 2006-07-04 MX MX2008000383A patent/MX2008000383A/es active IP Right Grant
- 2006-07-04 UA UAA200800190A patent/UA93047C2/ru unknown
- 2006-07-04 CN CN2006800322776A patent/CN101258154B/zh not_active Expired - Fee Related
- 2006-07-04 EA EA200800264A patent/EA013600B1/ru not_active IP Right Cessation
- 2006-07-04 WO PCT/EP2006/006613 patent/WO2007025596A1/en not_active Ceased
- 2006-07-04 DE DE602006014273T patent/DE602006014273D1/de active Active
- 2006-07-04 CA CA002614232A patent/CA2614232A1/en not_active Abandoned
- 2006-07-04 SI SI200630733T patent/SI1899350T1/sl unknown
- 2006-07-04 KR KR1020087000265A patent/KR20080037651A/ko not_active Ceased
- 2006-07-04 PT PT06818218T patent/PT1899350E/pt unknown
- 2006-07-04 DK DK06818218.7T patent/DK1899350T3/da active
-
2007
- 2007-12-12 ZA ZA200710798A patent/ZA200710798B/xx unknown
- 2007-12-17 IL IL188184A patent/IL188184A0/en unknown
- 2007-12-20 CR CR9622A patent/CR9622A/es not_active Application Discontinuation
-
2008
- 2008-01-09 MA MA30562A patent/MA29623B1/fr unknown
- 2008-01-30 NO NO20080563A patent/NO20080563L/no not_active Application Discontinuation
-
2010
- 2010-07-29 CY CY20101100713T patent/CY1110711T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2345841T3 (es) | 2010-10-04 |
| CN101258154A (zh) | 2008-09-03 |
| JP2009500366A (ja) | 2009-01-08 |
| WO2007025596A1 (en) | 2007-03-08 |
| EA200800264A1 (ru) | 2008-06-30 |
| MX2008000383A (es) | 2008-03-07 |
| CY1110711T1 (el) | 2015-06-10 |
| JP5145218B2 (ja) | 2013-02-13 |
| NO20080563L (no) | 2008-02-01 |
| EA013600B1 (ru) | 2010-06-30 |
| US7888347B2 (en) | 2011-02-15 |
| DE602006014273D1 (de) | 2010-06-24 |
| CN101258154B (zh) | 2011-01-19 |
| CR9622A (es) | 2008-04-10 |
| HRP20100401T1 (hr) | 2010-09-30 |
| IL188184A0 (en) | 2008-03-20 |
| UA93047C2 (ru) | 2011-01-10 |
| ATE467636T1 (de) | 2010-05-15 |
| DK1899350T3 (da) | 2010-09-06 |
| CA2614232A1 (en) | 2007-03-08 |
| GB0513886D0 (en) | 2005-08-10 |
| EP1899350A1 (en) | 2008-03-19 |
| PL1899350T3 (pl) | 2010-10-29 |
| PT1899350E (pt) | 2010-07-21 |
| EP1899350B1 (en) | 2010-05-12 |
| MA29623B1 (fr) | 2008-07-01 |
| AU2006286897A1 (en) | 2007-03-08 |
| ZA200710798B (en) | 2008-11-26 |
| KR20080037651A (ko) | 2008-04-30 |
| US20080176832A1 (en) | 2008-07-24 |
| BRPI0612719A2 (pt) | 2010-11-30 |
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