SI1836157T1 - Postopek priprave 1-amino-3,5-dimetiladamantan hidroklorida - Google Patents
Postopek priprave 1-amino-3,5-dimetiladamantan hidrokloridaInfo
- Publication number
- SI1836157T1 SI1836157T1 SI200630441T SI200630441T SI1836157T1 SI 1836157 T1 SI1836157 T1 SI 1836157T1 SI 200630441 T SI200630441 T SI 200630441T SI 200630441 T SI200630441 T SI 200630441T SI 1836157 T1 SI1836157 T1 SI 1836157T1
- Authority
- SI
- Slovenia
- Prior art keywords
- amino
- preparation
- dimethyladamantane hydrochloride
- hydrochloride
- dimethyladamantane
- Prior art date
Links
- LDDHMLJTFXJGPI-UHFFFAOYSA-N memantine hydrochloride Chemical compound Cl.C1C(C2)CC3(C)CC1(C)CC2(N)C3 LDDHMLJTFXJGPI-UHFFFAOYSA-N 0.000 title abstract 3
- 229960000967 memantine hydrochloride Drugs 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/33—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C211/34—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton
- C07C211/38—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of a saturated carbon skeleton containing condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64295705P | 2005-01-11 | 2005-01-11 | |
| US67759905P | 2005-05-03 | 2005-05-03 | |
| EP06718295A EP1836157B1 (en) | 2005-01-11 | 2006-01-11 | Process for the preparation of 1-amino-3,5-dimethyladamantane hydrochloride |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1836157T1 true SI1836157T1 (sl) | 2009-12-31 |
Family
ID=36282949
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200630441T SI1836157T1 (sl) | 2005-01-11 | 2006-01-11 | Postopek priprave 1-amino-3,5-dimetiladamantan hidroklorida |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US20060173215A1 (sl) |
| EP (2) | EP1836157B1 (sl) |
| AT (1) | ATE444950T1 (sl) |
| CA (2) | CA2591487A1 (sl) |
| DE (1) | DE602006009619D1 (sl) |
| ES (1) | ES2334579T3 (sl) |
| HR (1) | HRP20090676T1 (sl) |
| IL (2) | IL183237A0 (sl) |
| MX (2) | MX2007007302A (sl) |
| PT (1) | PT1836157E (sl) |
| SI (1) | SI1836157T1 (sl) |
| WO (2) | WO2006076560A1 (sl) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20050833A1 (it) | 2005-05-10 | 2006-11-11 | A M S A S P A Anonima Materie Sintetiche Affini | Nuovo procedimento per la sintesi di aminoadamantani |
| WO2007132476A2 (en) * | 2006-05-15 | 2007-11-22 | Matrix Laboratories Limited | A process for the preparation of memantine hydrochloride |
| US20080008752A1 (en) * | 2006-07-05 | 2008-01-10 | Julia Hrakovsky | Pharmaceutical compositions of memantine |
| CN101038280B (zh) * | 2007-04-11 | 2010-09-15 | 山东省医药工业研究所 | 一种盐酸美金刚中有关物质的hplc-elsd测定方法 |
| US20090247644A1 (en) * | 2008-03-28 | 2009-10-01 | Forest Laboratories Holdings Limited | Memantine formulations |
| ES2409692T3 (es) | 2008-12-17 | 2013-06-27 | Merz Pharma Gmbh & Co. Kgaa | Método para la producción de memantina |
| EP2555616A4 (en) * | 2010-04-08 | 2014-04-02 | Hetero Research Foundation | METHOD FOR PRODUCING MEMANTINE HYDROCHLORIDE |
| US8501816B2 (en) | 2010-10-12 | 2013-08-06 | Cerecor, Inc. | Antitussive compositions comprising memantine |
| CN102875387A (zh) * | 2012-10-23 | 2013-01-16 | 滨州泓瑞医药科技有限公司 | 一种盐酸金刚烷胺的制备工艺 |
| EP2949643A4 (en) * | 2013-01-23 | 2016-09-07 | Mitsubishi Gas Chemical Co | PROCESS FOR THE PRODUCTION OF MEMANTINE |
| US9701636B2 (en) | 2013-11-15 | 2017-07-11 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof |
| JP7174632B2 (ja) | 2016-06-23 | 2022-11-17 | コリウム， インコーポレイテッド | 親水性ドメインおよび疎水性ドメインならびに処置剤との接着剤マトリックス |
| AU2017301929B2 (en) | 2016-07-27 | 2023-03-02 | Corium Pharma Solutions, Inc. | Memantine transdermal delivery systems |
| EP3490559A1 (en) | 2016-07-27 | 2019-06-05 | Corium International, Inc. | Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery |
| CN116966166A (zh) | 2016-07-27 | 2023-10-31 | 考里安有限责任公司 | 碳酸氢钠原位转化驱动胺药物的透皮递送 |
| AU2018392686A1 (en) | 2017-12-20 | 2020-07-09 | Corium Pharma Solutions, Inc. | Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point |
| JP2019156756A (ja) * | 2018-03-13 | 2019-09-19 | 宇部興産株式会社 | １−アミノ−３，５−ジメチルアダマンタン塩酸塩の結晶 |
| BR112021024054A2 (pt) | 2019-05-31 | 2022-01-11 | Tecnimede Soc Tecnico Medicinal Sa | Composições farmacêuticas de combinação de dose fixa de liberação imediata, seus métodos e usos. |
| CN111909041B (zh) * | 2020-08-12 | 2023-06-16 | 山东罗欣药业集团恒欣药业有限公司 | 一种用于治疗神经功能疾病药物的制备方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3391142A (en) | 1966-02-09 | 1968-07-02 | Lilly Co Eli | Adamantyl secondary amines |
| NL7305644A (sl) * | 1972-04-20 | 1973-10-23 | ||
| DE58905637D1 (de) * | 1989-04-14 | 1993-10-21 | Merz & Co Gmbh & Co | Verwendung von Adamantan-Derivaten zur Prävention und Behandlung der cerebralen Ischämie. |
| US5614560A (en) * | 1991-04-04 | 1997-03-25 | Children's Medical Center Corporation | Method of preventing NMDA receptor-mediated neuronal damage |
| CZ282398B6 (cs) | 1994-04-13 | 1997-07-16 | Lachema A. S. | Způsob výroby 1-R1-3-R2-tricyklo(3,3,1,1,3,7)decyl-5-aminu |
| US5599998A (en) * | 1994-10-24 | 1997-02-04 | Iowa State University Research Foundation, Inc. | Method for the synthesis of adamantane amines |
| GB9812413D0 (en) * | 1998-06-10 | 1998-08-05 | Glaxo Group Ltd | Compound and its use |
| JP2002275142A (ja) | 2001-03-14 | 2002-09-25 | Daicel Chem Ind Ltd | アミド化合物の製造法 |
| CN1125033C (zh) | 2001-08-29 | 2003-10-22 | 中国科学院广州化学研究所 | 美金刚胺盐酸盐的合成方法 |
| CN1400205A (zh) | 2002-08-30 | 2003-03-05 | 中国科学院广州化学研究所 | 美金刚胺盐酸盐的制备方法 |
| CN1240668C (zh) * | 2003-09-10 | 2006-02-08 | 上海医药工业研究院 | 一种新的盐酸美金刚制备方法 |
| WO2005069742A2 (en) * | 2003-12-10 | 2005-08-04 | Sun Pharmaceutical Industries Limited | Crystal form ii of memantine hydrochloride |
| WO2005062724A2 (en) | 2003-12-31 | 2005-07-14 | Sun Pharmaceutical Industries Limited | Novel process for the preparation of aminoadamantane derivatives |
| WO2007132476A2 (en) | 2006-05-15 | 2007-11-22 | Matrix Laboratories Limited | A process for the preparation of memantine hydrochloride |
-
2006
- 2006-01-11 MX MX2007007302A patent/MX2007007302A/es unknown
- 2006-01-11 US US11/330,681 patent/US20060173215A1/en not_active Abandoned
- 2006-01-11 PT PT06718295T patent/PT1836157E/pt unknown
- 2006-01-11 EP EP06718295A patent/EP1836157B1/en active Active
- 2006-01-11 CA CA002591487A patent/CA2591487A1/en not_active Abandoned
- 2006-01-11 US US11/331,263 patent/US7462743B2/en not_active Expired - Fee Related
- 2006-01-11 WO PCT/US2006/001202 patent/WO2006076560A1/en active Application Filing
- 2006-01-11 AT AT06718295T patent/ATE444950T1/de not_active IP Right Cessation
- 2006-01-11 CA CA002591666A patent/CA2591666A1/en not_active Abandoned
- 2006-01-11 DE DE602006009619T patent/DE602006009619D1/de active Active
- 2006-01-11 WO PCT/US2006/001204 patent/WO2006076562A1/en active Application Filing
- 2006-01-11 SI SI200630441T patent/SI1836157T1/sl unknown
- 2006-01-11 EP EP06718293A patent/EP1836154A1/en not_active Withdrawn
- 2006-01-11 ES ES06718295T patent/ES2334579T3/es active Active
- 2006-01-11 MX MX2007007301A patent/MX2007007301A/es unknown
-
2007
- 2007-05-15 IL IL183237A patent/IL183237A0/en unknown
- 2007-05-15 IL IL183244A patent/IL183244A0/en unknown
-
2009
- 2009-12-17 HR HR20090676T patent/HRP20090676T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2006076562A1 (en) | 2006-07-20 |
| ATE444950T1 (de) | 2009-10-15 |
| US7462743B2 (en) | 2008-12-09 |
| US20060173215A1 (en) | 2006-08-03 |
| EP1836154A1 (en) | 2007-09-26 |
| IL183244A0 (en) | 2007-08-19 |
| HRP20090676T1 (hr) | 2010-01-31 |
| DE602006009619D1 (de) | 2009-11-19 |
| PT1836157E (pt) | 2009-11-24 |
| IL183237A0 (en) | 2007-08-19 |
| MX2007007301A (es) | 2008-02-11 |
| CA2591666A1 (en) | 2006-07-20 |
| ES2334579T3 (es) | 2010-03-12 |
| EP1836157B1 (en) | 2009-10-07 |
| MX2007007302A (es) | 2008-02-11 |
| EP1836157A1 (en) | 2007-09-26 |
| WO2006076560A1 (en) | 2006-07-20 |
| CA2591487A1 (en) | 2006-07-20 |
| US20060217573A1 (en) | 2006-09-28 |
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