ITMI20050833A1 - Nuovo procedimento per la sintesi di aminoadamantani - Google Patents

Nuovo procedimento per la sintesi di aminoadamantani

Info

Publication number
ITMI20050833A1
ITMI20050833A1 IT000833A ITMI20050833A ITMI20050833A1 IT MI20050833 A1 ITMI20050833 A1 IT MI20050833A1 IT 000833 A IT000833 A IT 000833A IT MI20050833 A ITMI20050833 A IT MI20050833A IT MI20050833 A1 ITMI20050833 A1 IT MI20050833A1
Authority
IT
Italy
Prior art keywords
aminoadamantani
synthesis
new procedure
hydrochloride
aminoadamantanes
Prior art date
Application number
IT000833A
Other languages
English (en)
Inventor
Ernesto Landonio
Simona Lanfranconi
Renato Molteni
Enrico Vigano'
Original Assignee
A M S A S P A Anonima Materie Sintetiche Affini
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A M S A S P A Anonima Materie Sintetiche Affini filed Critical A M S A S P A Anonima Materie Sintetiche Affini
Priority to IT000833A priority Critical patent/ITMI20050833A1/it
Priority to DE602006014054T priority patent/DE602006014054D1/de
Priority to AT06113681T priority patent/ATE466834T1/de
Priority to EP06113681A priority patent/EP1721888B1/en
Priority to ES06113681T priority patent/ES2345623T3/es
Priority to US11/431,175 priority patent/US7405324B2/en
Publication of ITMI20050833A1 publication Critical patent/ITMI20050833A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/10—Preparation of carboxylic acid amides from compounds not provided for in groups C07C231/02 - C07C231/08
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/62—Preparation of compounds containing amino groups bound to a carbon skeleton by cleaving carbon-to-nitrogen, sulfur-to-nitrogen, or phosphorus-to-nitrogen bonds, e.g. hydrolysis of amides, N-dealkylation of amines or quaternary ammonium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/08—Preparation of carboxylic acid amides from amides by reaction at nitrogen atoms of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00—Systems containing at least three condensed rings
    • C07C2603/56—Ring systems containing bridged rings
    • C07C2603/58—Ring systems containing bridged rings containing three rings
    • C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
    • C07C2603/74—Adamantanes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT000833A 2005-05-10 2005-05-10 Nuovo procedimento per la sintesi di aminoadamantani ITMI20050833A1 (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
IT000833A ITMI20050833A1 (it) 2005-05-10 2005-05-10 Nuovo procedimento per la sintesi di aminoadamantani
DE602006014054T DE602006014054D1 (de) 2005-05-10 2006-05-09 Verfahren zur Herstellung von Aminoadamantanen
AT06113681T ATE466834T1 (de) 2005-05-10 2006-05-09 Verfahren zur herstellung von aminoadamantanen
EP06113681A EP1721888B1 (en) 2005-05-10 2006-05-09 Process for synthesising aminoadamantanes
ES06113681T ES2345623T3 (es) 2005-05-10 2006-05-09 Procedimiento para sintetizar aminoadamantanos.
US11/431,175 US7405324B2 (en) 2005-05-10 2006-05-10 Process for synthesising aminoadamantanes

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000833A ITMI20050833A1 (it) 2005-05-10 2005-05-10 Nuovo procedimento per la sintesi di aminoadamantani

Publications (1)

Publication Number Publication Date
ITMI20050833A1 true ITMI20050833A1 (it) 2006-11-11

Family

ID=36699347

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000833A ITMI20050833A1 (it) 2005-05-10 2005-05-10 Nuovo procedimento per la sintesi di aminoadamantani

Country Status (6)

Country Link
US (1) US7405324B2 (it)
EP (1) EP1721888B1 (it)
AT (1) ATE466834T1 (it)
DE (1) DE602006014054D1 (it)
ES (1) ES2345623T3 (it)
IT (1) ITMI20050833A1 (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007132476A2 (en) * 2006-05-15 2007-11-22 Matrix Laboratories Limited A process for the preparation of memantine hydrochloride
WO2009151498A2 (en) * 2008-03-28 2009-12-17 Forest Laboratories Holdings Limited Memantine formulations
US8796491B2 (en) * 2008-08-08 2014-08-05 Merz Pharma Gmbh & Co. Kgaa Process for manufacturing adamantane derivatives with high yield
CN102432473A (zh) * 2011-11-23 2012-05-02 广州博济医药生物技术股份有限公司 一种盐酸美金刚的合成方法
EP2882291B1 (en) * 2012-08-07 2017-09-27 ZCL Chemicals Ltd. An improved process for the preparation of memantine hydrochloride

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3391142A (en) 1966-02-09 1968-07-02 Lilly Co Eli Adamantyl secondary amines
CA974518A (en) 1972-04-20 1975-09-16 Merz And Co. Procedure for the manufacture of 1,3,5 trisubstituted adamantan compounds
GB8332608D0 (en) * 1983-12-07 1984-01-11 Ici Plc Chemical process
DE10299048I2 (de) 1989-04-14 2006-07-13 Merz Pharma Gmbh & Co Kgaa Verwendung von Adamantan-Derivaten zur Pr{vention und Behandlung der cerebralen Isch{mie
CN1125033C (zh) 2001-08-29 2003-10-22 中国科学院广州化学研究所 美金刚胺盐酸盐的合成方法
WO2005062724A2 (en) * 2003-12-31 2005-07-14 Sun Pharmaceutical Industries Limited Novel process for the preparation of aminoadamantane derivatives
US20080275112A1 (en) * 2004-07-23 2008-11-06 Schreiner Peter R Invention Concerning Aminoadamantane Compounds
SI1836157T1 (sl) 2005-01-11 2009-12-31 Teva Pharm Fine Chemicals Srl Postopek priprave 1-amino-3,5-dimetiladamantan hidroklorida

Also Published As

Publication number Publication date
US7405324B2 (en) 2008-07-29
ATE466834T1 (de) 2010-05-15
EP1721888B1 (en) 2010-05-05
DE602006014054D1 (de) 2010-06-17
EP1721888A1 (en) 2006-11-15
ES2345623T3 (es) 2010-09-28
US20060258885A1 (en) 2006-11-16

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