SI1362040T1 - Process for the preparation of mesylates of piperazine derivatives - Google Patents

Process for the preparation of mesylates of piperazine derivatives

Info

Publication number
SI1362040T1
SI1362040T1 SI200230061T SI200230061T SI1362040T1 SI 1362040 T1 SI1362040 T1 SI 1362040T1 SI 200230061 T SI200230061 T SI 200230061T SI 200230061 T SI200230061 T SI 200230061T SI 1362040 T1 SI1362040 T1 SI 1362040T1
Authority
SI
Slovenia
Prior art keywords
mesylates
preparation
piperazine derivatives
piperazine
derivatives
Prior art date
Application number
SI200230061T
Other languages
English (en)
Slovenian (sl)
Inventor
Marcel P.M. Van Aar
Stefanus J. Schouten
Jan Zorgdrager
Michiel C. Heslinga
Original Assignee
Solvay Pharmaceuticals B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals B.V. filed Critical Solvay Pharmaceuticals B.V.
Publication of SI1362040T1 publication Critical patent/SI1362040T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
SI200230061T 2001-02-16 2002-02-14 Process for the preparation of mesylates of piperazine derivatives SI1362040T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01200534 2001-02-16
EP02719858A EP1362040B1 (en) 2001-02-16 2002-02-14 Process for the preparation of mesylates of piperazine derivatives
PCT/EP2002/001666 WO2002066449A2 (en) 2001-02-16 2002-02-14 Process for the preparation of mesylates of piperazine derivatives

Publications (1)

Publication Number Publication Date
SI1362040T1 true SI1362040T1 (en) 2005-06-30

Family

ID=8179894

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230061T SI1362040T1 (en) 2001-02-16 2002-02-14 Process for the preparation of mesylates of piperazine derivatives

Country Status (35)

Country Link
US (1) US7030241B2 (pt)
EP (1) EP1362040B1 (pt)
JP (1) JP4328528B2 (pt)
KR (2) KR100859106B1 (pt)
CN (1) CN1176079C (pt)
AR (1) AR034206A1 (pt)
AT (1) ATE284875T1 (pt)
AU (1) AU2002250962B2 (pt)
BG (1) BG66101B1 (pt)
BR (1) BR0205683A (pt)
CA (1) CA2422703C (pt)
CZ (1) CZ301780B6 (pt)
DE (1) DE60202261T2 (pt)
DK (1) DK1362040T3 (pt)
DZ (1) DZ3489A1 (pt)
ES (1) ES2230481T3 (pt)
HK (1) HK1059934A1 (pt)
HR (1) HRP20030610B1 (pt)
HU (1) HUP0400772A3 (pt)
IL (1) IL153509A (pt)
IS (1) IS2417B (pt)
ME (1) MEP37508A (pt)
MX (1) MXPA03002359A (pt)
MY (1) MY130687A (pt)
NO (1) NO324460B1 (pt)
NZ (1) NZ524632A (pt)
PL (1) PL208363B1 (pt)
PT (1) PT1362040E (pt)
RS (1) RS51126B (pt)
RU (1) RU2272036C2 (pt)
SI (1) SI1362040T1 (pt)
SK (1) SK286143B6 (pt)
UA (1) UA75390C2 (pt)
WO (1) WO2002066449A2 (pt)
ZA (1) ZA200301590B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7435738B2 (en) 2003-08-18 2008-10-14 Solvay Pharmaceuticals, Inc. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
AR045362A1 (es) * 2003-08-18 2005-10-26 Solvay Pharm Bv Forma cristalina estable de mesilato de bifeprunox (monometansulfonato de 7-[4-([1,1- bifenil] -3- ilmetil) -1- piperazinil] - 2-(3h) -benzoxazolona
US7405216B2 (en) * 2004-08-18 2008-07-29 Solvay Pharmaceuticals, B.V. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
US7423040B2 (en) * 2005-02-18 2008-09-09 Irene Eijgendaal Stable crystalline form of bifeprunox mesylate, dosage forms thereof and methods for using same
US7964604B2 (en) * 2005-02-18 2011-06-21 Solvay Pharmaceuticals B.V. Bifeprunox mesylate maintenance dose compositions and methods for using the same
US20070275977A1 (en) * 2006-05-02 2007-11-29 Van Aar Marcel P N-oxides of pyridylmethyl -piperazine and -piperidine derivatives
US7786126B2 (en) * 2006-06-16 2010-08-31 Solvay Pharmaceuticals B.V. Combination preparations comprising SLV308 and a dopamine agonist
US8106056B2 (en) * 2006-06-16 2012-01-31 Solvay Pharmaceuticals B.V. Combination preparations comprising bifeprunox and a dopamine agonist
BRPI0715445A2 (pt) 2006-08-31 2014-05-13 Solvay Pharm Bv Uso de um composto de bifeprunox, e, kit de titulação
US20090068290A1 (en) * 2006-08-31 2009-03-12 Michel Bourin Bifeprunox doses for treating schizophrenia
US20080132520A1 (en) * 2006-08-31 2008-06-05 Winsemius Antje A Compositions, kits and methods for administering a titration schedule comprising bifeprunox compounds
WO2009100258A1 (en) 2008-02-05 2009-08-13 Hollis-Eden Pharmaceuticals, Inc. Pharmaceutical solid state forms
WO2011023796A1 (en) 2009-08-31 2011-03-03 Abbott Healthcare Products B.V. Bifeprunox for treating addiction
UY32935A (es) 2009-10-12 2011-05-31 Abbott Healthcare Products Bv Polimorfos de pardoprunox

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE81975T1 (de) 1984-12-21 1992-11-15 Duphar Int Res Arzneimittel mit psychotroper wirkung.
EP0185429A1 (en) 1984-12-21 1986-06-25 Duphar International Research B.V New bicyclic heteroaryl piperazines
JPH0344383A (ja) * 1989-07-12 1991-02-26 Ihara Chem Ind Co Ltd 5―トリフルオロメチル―2―ハロメチルベンゾチアゾール類の製造法
JP3044383B2 (ja) * 1990-05-22 2000-05-22 コニカ株式会社 含窒素6員環化合物の製造方法
PT889889E (pt) * 1996-03-29 2007-01-31 Duphar Int Res Composto de piperazina e piperidina
SE9702799D0 (sv) * 1997-07-25 1997-07-25 Astra Ab New compounds
UA71590C2 (en) * 1998-11-13 2004-12-15 Duphar Int Res Piperazine and piperidine derivatives
US7435738B2 (en) 2003-08-18 2008-10-14 Solvay Pharmaceuticals, Inc. Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)

Also Published As

Publication number Publication date
WO2002066449A3 (en) 2002-10-24
NO324460B1 (no) 2007-10-22
DZ3489A1 (fr) 2002-08-29
IS6876A (is) 2003-07-17
HK1059934A1 (en) 2004-07-23
PL208363B1 (pl) 2011-04-29
MEP37508A (en) 2011-02-10
JP2004518741A (ja) 2004-06-24
HUP0400772A2 (hu) 2004-08-30
DE60202261D1 (de) 2005-01-20
PT1362040E (pt) 2005-05-31
CN1176079C (zh) 2004-11-17
JP4328528B2 (ja) 2009-09-09
EP1362040B1 (en) 2004-12-15
CA2422703A1 (en) 2002-08-29
BR0205683A (pt) 2004-07-06
HRP20030610B1 (en) 2006-02-28
DK1362040T3 (da) 2005-01-24
ES2230481T3 (es) 2005-05-01
CA2422703C (en) 2010-04-13
CZ301780B6 (cs) 2010-06-23
ATE284875T1 (de) 2005-01-15
RS51126B (sr) 2010-10-31
MY130687A (en) 2007-07-31
AR034206A1 (es) 2004-02-04
NO20031754D0 (no) 2003-04-15
AU2002250962B2 (en) 2006-08-24
HUP0400772A3 (en) 2008-02-28
DE60202261T2 (de) 2005-05-19
NO20031754L (no) 2003-04-15
BG66101B1 (bg) 2011-04-29
SK3092003A3 (en) 2003-09-11
CN1463268A (zh) 2003-12-24
IL153509A0 (en) 2003-07-06
KR20030077523A (ko) 2003-10-01
ZA200301590B (en) 2004-02-05
SK286143B6 (sk) 2008-04-07
HRP20030610A2 (en) 2005-06-30
IL153509A (en) 2007-12-03
US20040077631A1 (en) 2004-04-22
KR101000733B1 (ko) 2010-12-14
IS2417B (is) 2008-10-15
UA75390C2 (en) 2006-04-17
YU64403A (sh) 2006-05-25
BG108090A (bg) 2004-12-30
EP1362040A2 (en) 2003-11-19
US7030241B2 (en) 2006-04-18
MXPA03002359A (es) 2003-06-30
KR20080064206A (ko) 2008-07-08
KR100859106B1 (ko) 2008-09-18
RU2272036C2 (ru) 2006-03-20
WO2002066449A2 (en) 2002-08-29
CZ2003697A3 (cs) 2003-06-18
NZ524632A (en) 2004-03-26
PL369330A1 (en) 2005-04-18

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