SI1270576T1 - 3-phenyl-3,7-diazabicyclo(3,3,1)nonanes, process for their preparation and pharmaceutical compositions containing them - Google Patents

3-phenyl-3,7-diazabicyclo(3,3,1)nonanes, process for their preparation and pharmaceutical compositions containing them

Info

Publication number
SI1270576T1
SI1270576T1 SI200230027T SI200230027T SI1270576T1 SI 1270576 T1 SI1270576 T1 SI 1270576T1 SI 200230027 T SI200230027 T SI 200230027T SI 200230027 T SI200230027 T SI 200230027T SI 1270576 T1 SI1270576 T1 SI 1270576T1
Authority
SI
Slovenia
Prior art keywords
nonanes
diazabicyclo
phenyl
preparation
pharmaceutical compositions
Prior art date
Application number
SI200230027T
Other languages
English (en)
Slovenian (sl)
Inventor
Uwe Sch�N
Josef Messinger
Reinhard Br�Ckner
Dieter Ziegler
Original Assignee
Solvay Pharmaceuticals Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solvay Pharmaceuticals Gmbh filed Critical Solvay Pharmaceuticals Gmbh
Publication of SI1270576T1 publication Critical patent/SI1270576T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SI200230027T 2001-06-28 2002-06-22 3-phenyl-3,7-diazabicyclo(3,3,1)nonanes, process for their preparation and pharmaceutical compositions containing them SI1270576T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10131217A DE10131217A1 (de) 2001-06-28 2001-06-28 3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
SI1270576T1 true SI1270576T1 (en) 2005-02-28

Family

ID=7689787

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200230027T SI1270576T1 (en) 2001-06-28 2002-06-22 3-phenyl-3,7-diazabicyclo(3,3,1)nonanes, process for their preparation and pharmaceutical compositions containing them

Country Status (30)

Country Link
US (1) US6602880B2 (ko)
EP (1) EP1270576B1 (ko)
JP (1) JP4223237B2 (ko)
KR (1) KR20030002304A (ko)
CN (1) CN1303082C (ko)
AR (1) AR033772A1 (ko)
AT (1) ATE276254T1 (ko)
AU (1) AU781333B2 (ko)
BR (1) BR0202419A (ko)
CA (1) CA2391915C (ko)
CZ (1) CZ296878B6 (ko)
DE (2) DE10131217A1 (ko)
DK (1) DK1270576T3 (ko)
DZ (1) DZ3235A1 (ko)
ES (1) ES2229020T3 (ko)
HK (1) HK1051860A1 (ko)
HU (1) HUP0202057A3 (ko)
IL (1) IL150431A0 (ko)
MX (1) MXPA02006225A (ko)
NO (1) NO20023112L (ko)
NZ (1) NZ519811A (ko)
PL (1) PL207995B1 (ko)
PT (1) PT1270576E (ko)
RU (1) RU2299210C2 (ko)
SI (1) SI1270576T1 (ko)
SK (1) SK5862002A3 (ko)
TR (1) TR200402391T4 (ko)
TW (1) TWI256393B (ko)
UA (1) UA76707C2 (ko)
ZA (1) ZA200204063B (ko)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200418468A (en) * 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
WO2005094793A1 (en) * 2004-03-29 2005-10-13 Krka, Tovarna Zdravil, D.D., Novo Mesto Process for preparing a solid pharmaceutical composition
SI21800A (sl) * 2004-05-14 2005-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek sinteze perindoprila
CN102875550B (zh) * 2011-07-12 2016-01-06 常州合全药业有限公司 1,3,7-三取代-3,7-二氮杂双环[3,3,1]壬烷衍生物及制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2658558A1 (de) 1976-12-23 1978-06-29 Bayer Ag Diazabicyclo(3,3,1)nonane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
US4742217A (en) * 1986-06-02 1988-05-03 Honeywell Inc. Projection alignment and focusing aid
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
DE4402931A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel
DE4402933A1 (de) 1994-02-01 1995-08-03 Kali Chemie Pharma Gmbh Neue 3-Benzoyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
HK1051860A1 (en) 2003-08-22
EP1270576A3 (de) 2003-03-12
ATE276254T1 (de) 2004-10-15
DE50200996D1 (de) 2004-10-21
CA2391915C (en) 2010-08-24
KR20030002304A (ko) 2003-01-08
DZ3235A1 (fr) 2005-04-20
PL207995B1 (pl) 2011-02-28
PT1270576E (pt) 2004-11-30
AR033772A1 (es) 2004-01-07
HUP0202057A3 (en) 2003-05-28
US20030109541A1 (en) 2003-06-12
CN1394860A (zh) 2003-02-05
CN1303082C (zh) 2007-03-07
EP1270576B1 (de) 2004-09-15
DE10131217A1 (de) 2003-01-09
ZA200204063B (en) 2003-01-23
CZ296878B6 (cs) 2006-07-12
RU2002117066A (ru) 2004-02-20
CZ20021856A3 (cs) 2003-02-12
TR200402391T4 (tr) 2004-12-21
CA2391915A1 (en) 2002-12-28
JP4223237B2 (ja) 2009-02-12
ES2229020T3 (es) 2005-04-16
DK1270576T3 (da) 2004-10-11
HUP0202057A2 (hu) 2003-01-28
PL354774A1 (en) 2002-12-30
HU0202057D0 (ko) 2002-09-28
NO20023112D0 (no) 2002-06-27
SK5862002A3 (en) 2003-01-09
AU5064402A (en) 2003-01-02
JP2003026677A (ja) 2003-01-29
EP1270576A2 (de) 2003-01-02
IL150431A0 (en) 2002-12-01
AU781333B2 (en) 2005-05-19
NO20023112L (no) 2002-12-30
RU2299210C2 (ru) 2007-05-20
TWI256393B (en) 2006-06-11
UA76707C2 (uk) 2006-09-15
MXPA02006225A (es) 2005-02-17
BR0202419A (pt) 2003-04-29
US6602880B2 (en) 2003-08-05
NZ519811A (en) 2004-03-26

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SI1270576T1 (en) 3-phenyl-3,7-diazabicyclo(3,3,1)nonanes, process for their preparation and pharmaceutical compositions containing them