SI1189602T1 - Mikrogranule morfin sulfata, postopek izdelave in sestavek, ki jih vsebuje - Google Patents

Mikrogranule morfin sulfata, postopek izdelave in sestavek, ki jih vsebuje

Info

Publication number
SI1189602T1
SI1189602T1 SI200030946T SI200030946T SI1189602T1 SI 1189602 T1 SI1189602 T1 SI 1189602T1 SI 200030946 T SI200030946 T SI 200030946T SI 200030946 T SI200030946 T SI 200030946T SI 1189602 T1 SI1189602 T1 SI 1189602T1
Authority
SI
Slovenia
Prior art keywords
same
compositions containing
morphine sulphate
preparing
microgranules
Prior art date
Application number
SI200030946T
Other languages
English (en)
Slovenian (sl)
Inventor
Dominique Marechal
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9546553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1189602(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm Sa filed Critical Ethypharm Sa
Publication of SI1189602T1 publication Critical patent/SI1189602T1/sl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
SI200030946T 1999-06-09 2000-06-08 Mikrogranule morfin sulfata, postopek izdelave in sestavek, ki jih vsebuje SI1189602T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9907259A FR2794646B1 (fr) 1999-06-09 1999-06-09 Microgranules de sulfate de morphine, procede de preparation et composition les contenant
PCT/FR2000/001573 WO2000074659A1 (fr) 1999-06-09 2000-06-08 Microgranules de sulfate de morphine, procede de preparation et composition les contenant
EP00940460A EP1189602B1 (fr) 1999-06-09 2000-06-08 Microgranules de sulfate de morphine, procede de preparation et composition les contenant

Publications (1)

Publication Number Publication Date
SI1189602T1 true SI1189602T1 (sl) 2007-06-30

Family

ID=9546553

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030946T SI1189602T1 (sl) 1999-06-09 2000-06-08 Mikrogranule morfin sulfata, postopek izdelave in sestavek, ki jih vsebuje

Country Status (24)

Country Link
US (2) US7063864B1 (enExample)
EP (3) EP1189602B1 (enExample)
JP (1) JP4296562B2 (enExample)
KR (1) KR100676123B1 (enExample)
CN (1) CN1267089C (enExample)
AR (2) AR024313A1 (enExample)
AT (2) ATE354356T1 (enExample)
AU (1) AU769160C (enExample)
BR (1) BRPI0011404B8 (enExample)
CA (1) CA2376339C (enExample)
CO (1) CO5160317A1 (enExample)
CY (1) CY1107612T1 (enExample)
DE (1) DE60033519T2 (enExample)
DK (2) DK1189602T3 (enExample)
ES (2) ES2280226T3 (enExample)
FR (1) FR2794646B1 (enExample)
HK (1) HK1045107B (enExample)
MX (1) MXPA01012751A (enExample)
NZ (1) NZ516077A (enExample)
PT (2) PT1627631E (enExample)
SI (1) SI1189602T1 (enExample)
TW (1) TWI224510B (enExample)
WO (1) WO2000074659A1 (enExample)
ZA (1) ZA200110087B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant
JP4848101B2 (ja) * 2001-08-17 2011-12-28 株式会社フジモト・コーポレーション 徐放性マイクロペレット
EP1429739A1 (en) 2001-09-21 2004-06-23 Egalet A/S Polymer release system
EP1429744A1 (en) 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
DE602004031096D1 (de) 2003-03-26 2011-03-03 Egalet As Morphin-system mit kontrollierter freisetzung
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20100233257A1 (en) * 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) * 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
CA2687192C (en) 2007-06-04 2015-11-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
US20190038769A1 (en) * 2010-12-01 2019-02-07 Gowey Research Group, Pllc Micro-rna profiling, compositions, and methods of treating diseases
JP2012250926A (ja) * 2011-06-01 2012-12-20 Nitto Denko Corp 粒子製剤
US9549899B2 (en) 2012-07-06 2017-01-24 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
IL273627B2 (en) 2017-12-20 2025-03-01 Purdue Pharma Lp Morphine sulfate dosage forms for abuse deterrence

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8514665D0 (en) 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
CA2007181C (en) 1989-01-06 1998-11-24 Angelo Mario Morella Sustained release pharmaceutical composition
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
GB9117361D0 (en) * 1991-08-12 1991-09-25 Euro Celtique Sa Oral dosage form
GB9119958D0 (en) 1991-09-18 1991-10-30 Unilever Plc Detergent compositions
US5286493A (en) 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
SE9301057L (sv) 1993-03-30 1994-10-01 Pharmacia Ab Beredning med kontrollerad frisättning
HU218673B (hu) * 1993-10-07 2000-10-28 Euroceltique S.A. Opioid analgetikumot tartalmazó elnyújtott hatóanyag-felszabadítású orális gyógyszerkészítmény és eljárás előállítására
US5411745A (en) 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
US5460826A (en) 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant

Also Published As

Publication number Publication date
US20070003620A1 (en) 2007-01-04
FR2794646A1 (fr) 2000-12-15
AU769160C (en) 2006-02-23
KR20020031338A (ko) 2002-05-01
CN1390121A (zh) 2003-01-08
MXPA01012751A (es) 2002-07-02
EP1627631A2 (fr) 2006-02-22
DE60033519T2 (de) 2007-10-31
WO2000074659A1 (fr) 2000-12-14
CO5160317A1 (es) 2002-05-30
AR024313A1 (es) 2002-09-25
AR068015A2 (es) 2009-10-28
HK1045107A1 (en) 2002-11-15
ATE544448T1 (de) 2012-02-15
BR0011404A (pt) 2002-03-05
JP2003520770A (ja) 2003-07-08
TWI224510B (en) 2004-12-01
KR100676123B1 (ko) 2007-01-31
EP1189602B1 (fr) 2007-02-21
DK1189602T3 (da) 2007-07-02
BR0011404B1 (pt) 2013-03-05
CY1107612T1 (el) 2013-03-13
EP1627631B1 (fr) 2012-02-08
HK1045107B (zh) 2007-05-11
ES2379688T3 (es) 2012-04-30
DE60033519D1 (de) 2007-04-05
DK1627631T3 (da) 2012-04-30
AU5539400A (en) 2000-12-28
US7063864B1 (en) 2006-06-20
EP1189602A1 (fr) 2002-03-27
ZA200110087B (en) 2003-03-03
ES2280226T3 (es) 2007-09-16
EP1818051A1 (fr) 2007-08-15
CN1267089C (zh) 2006-08-02
BRPI0011404B8 (pt) 2021-05-25
AU769160B2 (en) 2004-01-15
CA2376339A1 (fr) 2000-12-14
CA2376339C (fr) 2011-05-17
PT1189602E (pt) 2007-05-31
ATE354356T1 (de) 2007-03-15
FR2794646B1 (fr) 2001-09-21
NZ516077A (en) 2004-06-25
JP4296562B2 (ja) 2009-07-15
EP1627631A3 (fr) 2006-03-15
PT1627631E (pt) 2012-05-21

Similar Documents

Publication Publication Date Title
EP1243335A4 (en) CATALYST AND METHOD FOR THE PRODUCTION THEREOF
HUP0100347A3 (en) Gastroprotected omerprazole microgranules, method for obtaining same and pharmaceutical preparation
HUP9800857A3 (en) Pesticide compositions, method for preparing and using thereof
IL139849A0 (en) Method for making 4-carboxyamino-2-substituted 1,2,3,4-tetrahydroquinoline
SI1189602T1 (sl) Mikrogranule morfin sulfata, postopek izdelave in sestavek, ki jih vsebuje
EG23819A (en) Method for preparing of l-phenylephrine-hydrochloride
HUP0302968A3 (en) Aminoalkylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same
CZ20012118A3 (cs) Způsob výroby 3-alkanoylindolu a 3-alkylindolu
SG92758A1 (en) Method for preparing biocompatible scaffold and scaffold prepared therefrom
AU2429899A (en) Morphine sulphate microgranules, method for making same and pharmaceutical preparations
HUP0302961A3 (en) Aminoalkoxybenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same
EG24350A (en) Prilling method
HUP0103316A3 (en) 2-ureido-pyrimidone derivatives, method for producing them, pharmaceutical compositions containing them and their use
EP1146136A4 (en) ORNAMENT AND METHOD FOR ITS MANUFACTURE
HUP0001551A3 (en) Improved method for producing thiazolidinediones, thiazolidinediones and pharmaceutical compositions containing the same
HUP0003861A3 (en) Quinolin-4-yl derivatives, process for producing them and pharmaceutical compositions containing them
GB9920271D0 (en) Flavouring agent and methods for preparing and using same
HUP0200928A3 (en) Pyrido-thieno-diazepines, method for the production thereof and pharmaceutical compositions containing said pyrido-thieno-diazepines
GB9917593D0 (en) Compound, composition, process and use
HUP0204572A3 (en) Substituierte bisindolylmaleinimide derivatives, process for their preparation and use and pharmaceutcial compositions containing them
HUP0102772A3 (en) Novel compounds derived from alpha-d-xylose, preparation method and therapeutic use
AU2910900A (en) Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ols, method for producing them and their use as medicaments
HUP0200369A3 (en) Method for producing cyclo-(asp-dphe-nmeval-arg-gly)
GB9920270D0 (en) Flavouring agent and methods for preparing and using same
HUP0302892A3 (en) Aminoalkenylbenzoyl-benzofuran or benzothiophene derivatives, method for preparing same and compositions containing same