BR0011404B1 - microgrÂnulos de sulfato de morfina de liberaÇço prolongada, processo de preparaÇço dos mesmos e composiÇço farmacÊutica. - Google Patents
microgrÂnulos de sulfato de morfina de liberaÇço prolongada, processo de preparaÇço dos mesmos e composiÇço farmacÊutica.Info
- Publication number
- BR0011404B1 BR0011404B1 BRPI0011404-9A BR0011404A BR0011404B1 BR 0011404 B1 BR0011404 B1 BR 0011404B1 BR 0011404 A BR0011404 A BR 0011404A BR 0011404 B1 BR0011404 B1 BR 0011404B1
- Authority
- BR
- Brazil
- Prior art keywords
- microgranules
- pharmaceutical composition
- sustained release
- preparing same
- morphine sulfate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/501—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9907259A FR2794646B1 (fr) | 1999-06-09 | 1999-06-09 | Microgranules de sulfate de morphine, procede de preparation et composition les contenant |
PCT/FR2000/001573 WO2000074659A1 (fr) | 1999-06-09 | 2000-06-08 | Microgranules de sulfate de morphine, procede de preparation et composition les contenant |
Publications (3)
Publication Number | Publication Date |
---|---|
BR0011404A BR0011404A (pt) | 2002-03-05 |
BR0011404B1 true BR0011404B1 (pt) | 2013-03-05 |
BRPI0011404B8 BRPI0011404B8 (pt) | 2021-05-25 |
Family
ID=9546553
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0011404A BRPI0011404B8 (pt) | 1999-06-09 | 2000-06-08 | microgrânulos de sulfato de morfina de liberação prolongada, processo de preparação dos mesmos e composição farmacêutica. |
Country Status (24)
Country | Link |
---|---|
US (2) | US7063864B1 (pt) |
EP (3) | EP1189602B1 (pt) |
JP (1) | JP4296562B2 (pt) |
KR (1) | KR100676123B1 (pt) |
CN (1) | CN1267089C (pt) |
AR (2) | AR024313A1 (pt) |
AT (2) | ATE354356T1 (pt) |
AU (1) | AU769160C (pt) |
BR (1) | BRPI0011404B8 (pt) |
CA (1) | CA2376339C (pt) |
CO (1) | CO5160317A1 (pt) |
CY (1) | CY1107612T1 (pt) |
DE (1) | DE60033519T2 (pt) |
DK (2) | DK1189602T3 (pt) |
ES (2) | ES2280226T3 (pt) |
FR (1) | FR2794646B1 (pt) |
HK (1) | HK1045107B (pt) |
MX (1) | MXPA01012751A (pt) |
NZ (1) | NZ516077A (pt) |
PT (2) | PT1627631E (pt) |
SI (1) | SI1189602T1 (pt) |
TW (1) | TWI224510B (pt) |
WO (1) | WO2000074659A1 (pt) |
ZA (1) | ZA200110087B (pt) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2794646B1 (fr) * | 1999-06-09 | 2001-09-21 | Ethypharm Lab Prod Ethiques | Microgranules de sulfate de morphine, procede de preparation et composition les contenant |
JP4848101B2 (ja) * | 2001-08-17 | 2011-12-28 | 株式会社フジモト・コーポレーション | 徐放性マイクロペレット |
WO2003024430A1 (en) | 2001-09-21 | 2003-03-27 | Egalet A/S | Morphine polymer release system |
EP2957281A1 (en) | 2001-09-21 | 2015-12-23 | Egalet Ltd. | Polymer release system |
ES2360102T3 (es) | 2003-03-26 | 2011-05-31 | Egalet A/S | Sistema para la liberación controlada de morfina. |
FR2883179B1 (fr) | 2005-03-18 | 2009-04-17 | Ethypharm Sa | Comprime enrobe |
US20070286900A1 (en) | 2006-06-09 | 2007-12-13 | Catherine Herry | Low dose tablets of opioid analgesics and preparation process |
US20100233257A1 (en) * | 2006-06-09 | 2010-09-16 | Ethypharm | Low dose sublingual tablets of opioid analgesics and preparation process |
EP2155167A2 (en) | 2007-06-04 | 2010-02-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
EP2393484A1 (en) | 2009-02-06 | 2011-12-14 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
AU2010265213B2 (en) | 2009-06-24 | 2012-08-23 | Egalet Ltd. | Controlled release formulations |
US20190038769A1 (en) * | 2010-12-01 | 2019-02-07 | Gowey Research Group, Pllc | Micro-rna profiling, compositions, and methods of treating diseases |
JP2012250926A (ja) * | 2011-06-01 | 2012-12-20 | Nitto Denko Corp | 粒子製剤 |
US9549899B2 (en) | 2012-07-06 | 2017-01-24 | Egalet Ltd. | Abuse deterrent pharmaceutical compositions for controlled release |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8514665D0 (en) | 1985-06-11 | 1985-07-10 | Eroceltique Sa | Oral pharmaceutical composition |
CA2007181C (en) | 1989-01-06 | 1998-11-24 | Angelo Mario Morella | Sustained release pharmaceutical composition |
US5133974A (en) | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
GB9117361D0 (en) * | 1991-08-12 | 1991-09-25 | Euro Celtique Sa | Oral dosage form |
GB9119958D0 (en) | 1991-09-18 | 1991-10-30 | Unilever Plc | Detergent compositions |
US5968551A (en) * | 1991-12-24 | 1999-10-19 | Purdue Pharma L.P. | Orally administrable opioid formulations having extended duration of effect |
US5286493A (en) | 1992-01-27 | 1994-02-15 | Euroceltique, S.A. | Stabilized controlled release formulations having acrylic polymer coating |
US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
SE9301057L (sv) | 1993-03-30 | 1994-10-01 | Pharmacia Ab | Beredning med kontrollerad frisättning |
EP0647448A1 (en) * | 1993-10-07 | 1995-04-12 | Euroceltique S.A. | Orally administrable opioid formulations having extended duration of effect |
US5411745A (en) | 1994-05-25 | 1995-05-02 | Euro-Celtique, S.A. | Powder-layered morphine sulfate formulations |
US5460826A (en) | 1994-06-27 | 1995-10-24 | Alza Corporation | Morphine therapy |
GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
FR2771291B1 (fr) | 1997-11-21 | 2000-02-25 | Ethypharm Lab Prod Ethiques | Spheroides, procede de preparation et compositions pharmaceutiques |
FR2794646B1 (fr) * | 1999-06-09 | 2001-09-21 | Ethypharm Lab Prod Ethiques | Microgranules de sulfate de morphine, procede de preparation et composition les contenant |
-
1999
- 1999-06-09 FR FR9907259A patent/FR2794646B1/fr not_active Expired - Lifetime
-
2000
- 2000-06-06 CO CO00041883A patent/CO5160317A1/es unknown
- 2000-06-07 AR ARP000102831A patent/AR024313A1/es not_active Application Discontinuation
- 2000-06-08 KR KR1020017015784A patent/KR100676123B1/ko active IP Right Grant
- 2000-06-08 MX MXPA01012751A patent/MXPA01012751A/es active IP Right Grant
- 2000-06-08 DK DK00940460T patent/DK1189602T3/da active
- 2000-06-08 PT PT05111290T patent/PT1627631E/pt unknown
- 2000-06-08 DK DK05111290.2T patent/DK1627631T3/da active
- 2000-06-08 NZ NZ516077A patent/NZ516077A/en not_active IP Right Cessation
- 2000-06-08 WO PCT/FR2000/001573 patent/WO2000074659A1/fr active IP Right Grant
- 2000-06-08 EP EP00940460A patent/EP1189602B1/fr not_active Expired - Lifetime
- 2000-06-08 US US10/009,341 patent/US7063864B1/en not_active Expired - Lifetime
- 2000-06-08 SI SI200030946T patent/SI1189602T1/sl unknown
- 2000-06-08 EP EP05111290A patent/EP1627631B1/fr not_active Expired - Lifetime
- 2000-06-08 CN CNB008086052A patent/CN1267089C/zh not_active Expired - Lifetime
- 2000-06-08 JP JP2001501196A patent/JP4296562B2/ja not_active Expired - Lifetime
- 2000-06-08 EP EP07102671A patent/EP1818051A1/fr not_active Withdrawn
- 2000-06-08 PT PT00940460T patent/PT1189602E/pt unknown
- 2000-06-08 AT AT00940460T patent/ATE354356T1/de active
- 2000-06-08 ES ES00940460T patent/ES2280226T3/es not_active Expired - Lifetime
- 2000-06-08 CA CA2376339A patent/CA2376339C/fr not_active Expired - Lifetime
- 2000-06-08 DE DE60033519T patent/DE60033519T2/de not_active Expired - Lifetime
- 2000-06-08 BR BRPI0011404A patent/BRPI0011404B8/pt not_active IP Right Cessation
- 2000-06-08 AT AT05111290T patent/ATE544448T1/de active
- 2000-06-08 ES ES05111290T patent/ES2379688T3/es not_active Expired - Lifetime
- 2000-06-08 AU AU55394/00A patent/AU769160C/en not_active Expired
- 2000-06-27 TW TW089111207A patent/TWI224510B/zh not_active IP Right Cessation
-
2001
- 2001-12-07 ZA ZA200110087A patent/ZA200110087B/xx unknown
-
2002
- 2002-08-13 HK HK02105909.7A patent/HK1045107B/zh unknown
-
2006
- 2006-05-26 US US11/441,349 patent/US20070003620A1/en not_active Abandoned
-
2007
- 2007-04-05 CY CY20071100489T patent/CY1107612T1/el unknown
-
2008
- 2008-08-22 AR ARP080103672A patent/AR068015A2/es not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 05/03/2013, OBSERVADAS AS CONDICOES LEGAIS. |
|
B16C | Correction of notification of the grant [chapter 16.3 patent gazette] |
Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 08/06/2000 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF |
|
B21A | Patent or certificate of addition expired [chapter 21.1 patent gazette] |
Free format text: PATENTE EXTINTA EM 08/06/2020 |