CY1107612T1 - Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους - Google Patents

Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους

Info

Publication number
CY1107612T1
CY1107612T1 CY20071100489T CY071100489T CY1107612T1 CY 1107612 T1 CY1107612 T1 CY 1107612T1 CY 20071100489 T CY20071100489 T CY 20071100489T CY 071100489 T CY071100489 T CY 071100489T CY 1107612 T1 CY1107612 T1 CY 1107612T1
Authority
CY
Cyprus
Prior art keywords
morphine sulfate
morphokes
compositions
preparation
granules
Prior art date
Application number
CY20071100489T
Other languages
Greek (el)
English (en)
Inventor
Dominique Marechal
Pascal Oury
Pascal Suplie
Original Assignee
Ethypharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9546553&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1107612(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ethypharm filed Critical Ethypharm
Publication of CY1107612T1 publication Critical patent/CY1107612T1/el

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/501—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CY20071100489T 1999-06-09 2007-04-05 Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους CY1107612T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9907259A FR2794646B1 (fr) 1999-06-09 1999-06-09 Microgranules de sulfate de morphine, procede de preparation et composition les contenant
EP00940460A EP1189602B1 (fr) 1999-06-09 2000-06-08 Microgranules de sulfate de morphine, procede de preparation et composition les contenant

Publications (1)

Publication Number Publication Date
CY1107612T1 true CY1107612T1 (el) 2013-03-13

Family

ID=9546553

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100489T CY1107612T1 (el) 1999-06-09 2007-04-05 Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους

Country Status (24)

Country Link
US (2) US7063864B1 (enExample)
EP (3) EP1189602B1 (enExample)
JP (1) JP4296562B2 (enExample)
KR (1) KR100676123B1 (enExample)
CN (1) CN1267089C (enExample)
AR (2) AR024313A1 (enExample)
AT (2) ATE354356T1 (enExample)
AU (1) AU769160C (enExample)
BR (1) BRPI0011404B8 (enExample)
CA (1) CA2376339C (enExample)
CO (1) CO5160317A1 (enExample)
CY (1) CY1107612T1 (enExample)
DE (1) DE60033519T2 (enExample)
DK (2) DK1189602T3 (enExample)
ES (2) ES2280226T3 (enExample)
FR (1) FR2794646B1 (enExample)
HK (1) HK1045107B (enExample)
MX (1) MXPA01012751A (enExample)
NZ (1) NZ516077A (enExample)
PT (2) PT1627631E (enExample)
SI (1) SI1189602T1 (enExample)
TW (1) TWI224510B (enExample)
WO (1) WO2000074659A1 (enExample)
ZA (1) ZA200110087B (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant
JP4848101B2 (ja) * 2001-08-17 2011-12-28 株式会社フジモト・コーポレーション 徐放性マイクロペレット
EP1429739A1 (en) 2001-09-21 2004-06-23 Egalet A/S Polymer release system
EP1429744A1 (en) 2001-09-21 2004-06-23 Egalet A/S Morphine polymer release system
DE602004031096D1 (de) 2003-03-26 2011-03-03 Egalet As Morphin-system mit kontrollierter freisetzung
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20100233257A1 (en) * 2006-06-09 2010-09-16 Ethypharm Low dose sublingual tablets of opioid analgesics and preparation process
US20070286900A1 (en) * 2006-06-09 2007-12-13 Catherine Herry Low dose tablets of opioid analgesics and preparation process
CA2687192C (en) 2007-06-04 2015-11-24 Egalet A/S Controlled release pharmaceutical compositions for prolonged effect
NZ594207A (en) 2009-02-06 2013-03-28 Egalet Ltd Immediate release composition resistant to abuse by intake of alcohol
NZ597283A (en) 2009-06-24 2013-07-26 Egalet Ltd Controlled release formulations
US20190038769A1 (en) * 2010-12-01 2019-02-07 Gowey Research Group, Pllc Micro-rna profiling, compositions, and methods of treating diseases
JP2012250926A (ja) * 2011-06-01 2012-12-20 Nitto Denko Corp 粒子製剤
US9549899B2 (en) 2012-07-06 2017-01-24 Egalet Ltd. Abuse deterrent pharmaceutical compositions for controlled release
IL273627B2 (en) 2017-12-20 2025-03-01 Purdue Pharma Lp Morphine sulfate dosage forms for abuse deterrence

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8514665D0 (en) 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
CA2007181C (en) 1989-01-06 1998-11-24 Angelo Mario Morella Sustained release pharmaceutical composition
US5133974A (en) 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
GB9117361D0 (en) * 1991-08-12 1991-09-25 Euro Celtique Sa Oral dosage form
GB9119958D0 (en) 1991-09-18 1991-10-30 Unilever Plc Detergent compositions
US5286493A (en) 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5580578A (en) 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
SE9301057L (sv) 1993-03-30 1994-10-01 Pharmacia Ab Beredning med kontrollerad frisättning
HU218673B (hu) * 1993-10-07 2000-10-28 Euroceltique S.A. Opioid analgetikumot tartalmazó elnyújtott hatóanyag-felszabadítású orális gyógyszerkészítmény és eljárás előállítására
US5411745A (en) 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
US5460826A (en) 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
FR2771291B1 (fr) * 1997-11-21 2000-02-25 Ethypharm Lab Prod Ethiques Spheroides, procede de preparation et compositions pharmaceutiques
FR2794646B1 (fr) * 1999-06-09 2001-09-21 Ethypharm Lab Prod Ethiques Microgranules de sulfate de morphine, procede de preparation et composition les contenant

Also Published As

Publication number Publication date
US20070003620A1 (en) 2007-01-04
FR2794646A1 (fr) 2000-12-15
AU769160C (en) 2006-02-23
KR20020031338A (ko) 2002-05-01
CN1390121A (zh) 2003-01-08
MXPA01012751A (es) 2002-07-02
EP1627631A2 (fr) 2006-02-22
DE60033519T2 (de) 2007-10-31
WO2000074659A1 (fr) 2000-12-14
CO5160317A1 (es) 2002-05-30
AR024313A1 (es) 2002-09-25
AR068015A2 (es) 2009-10-28
HK1045107A1 (en) 2002-11-15
ATE544448T1 (de) 2012-02-15
BR0011404A (pt) 2002-03-05
JP2003520770A (ja) 2003-07-08
TWI224510B (en) 2004-12-01
KR100676123B1 (ko) 2007-01-31
EP1189602B1 (fr) 2007-02-21
DK1189602T3 (da) 2007-07-02
BR0011404B1 (pt) 2013-03-05
EP1627631B1 (fr) 2012-02-08
HK1045107B (zh) 2007-05-11
ES2379688T3 (es) 2012-04-30
DE60033519D1 (de) 2007-04-05
DK1627631T3 (da) 2012-04-30
AU5539400A (en) 2000-12-28
US7063864B1 (en) 2006-06-20
EP1189602A1 (fr) 2002-03-27
ZA200110087B (en) 2003-03-03
ES2280226T3 (es) 2007-09-16
EP1818051A1 (fr) 2007-08-15
CN1267089C (zh) 2006-08-02
BRPI0011404B8 (pt) 2021-05-25
AU769160B2 (en) 2004-01-15
CA2376339A1 (fr) 2000-12-14
CA2376339C (fr) 2011-05-17
PT1189602E (pt) 2007-05-31
ATE354356T1 (de) 2007-03-15
FR2794646B1 (fr) 2001-09-21
NZ516077A (en) 2004-06-25
JP4296562B2 (ja) 2009-07-15
SI1189602T1 (sl) 2007-06-30
EP1627631A3 (fr) 2006-03-15
PT1627631E (pt) 2012-05-21

Similar Documents

Publication Publication Date Title
CY1107612T1 (el) Μικροκοκκοι θειικης μορφινης, μεθοδος παρασκευης τους, και συνθεσεις περιεχουσες αυτους
CY1108914T1 (el) Μητρα για παρατεταμενη, αμεταβλητη και ανεξαρτητη απελευθερωση δραστικων ενωσεων
NO20000284D0 (no) Tanninsyre-polymerblandinger for kontrollert frigivelse av farmasoeytiske midler, saerlig i munnhulen
EA200501863A1 (ru) Полимерные производные, имеющие специфические атомные структуры
CY1108074T1 (el) Ανοσολογικες μεθοδοι για τη ρυθμιση της μυοστατινης σε σπονδυλωτα
FR2741066B1 (fr) Nouveaux agents de transfection et leurs applications pharmaceutiques
BR0109107A (pt) Usos terapêuticos de mediadores ppar
BR0107942A (pt) Polìmeros de proteìna de liberação lenta
DK0809666T4 (da) Biologisk nedbrydelige polymerer, fremgangsmåder til deres fremstilling samt deres anvendelse til fremstilling af bionedbrydelige formlegemer
CY1105963T1 (el) Συνθεσεις καψομepιδιακου εμβολιου του ιου του θηλωματος και μεθοδοι χρησης
FR2779438B1 (fr) Gel stable, son procede de preparation, et compositions pharmaceutiques le comprenant
ATE29215T1 (de) Diaethylpropionpraeparate mit verzoegerter wirkung.
EE200000065A (et) Bioloogiliselt aktiivseid makromolekule ja vett sisaldavad aerosoolpreparaadid ja nende aerosoolide saamise meetod
DK1036058T3 (da) Adamantanderivater
DK1036059T3 (da) Adamantanderivater
PT1093819E (pt) Compostos e composicoes para fornecimento de agentes activos
TR200003787A3 (tr) Kararli yavas salimli oral dozaj bilesimi.
ATE286387T1 (de) Clarithromycin enthaltende zubereitung mit verlängerter freisetzung
TR200201250T2 (tr) Hidroksieikosatetraenoat tuzları, bileşimleri ve bunların göz kuruması bozukluklarının iyileştirilmesinde kullanım yöntemleri.
PT975334E (pt) Microparticulas biodegradaveis para a libertacao sustentada de farmacos terapeuticos
DE69635987D1 (de) Verbesserte liposomale formulierung
FI19991806L (fi) Uusia koostumuksia biologisesti aktiivisen aineen säädettyyn vapauttamiseen, ja niiden valmistus
DE60113445D1 (de) Substanzen mit verzweigten linkermolekülen
DK1169032T3 (da) Ketoprofen-mikrogranuler, fremgangsmåde til fremstilling deraf og farmaceutiske præparater
NO942396L (no) Preparat med vedvarende frigiving av anti-endotelin substans