SI1150960T1 - - Google Patents
Info
- Publication number
- SI1150960T1 SI1150960T1 SI200030663T SI200030663T SI1150960T1 SI 1150960 T1 SI1150960 T1 SI 1150960T1 SI 200030663 T SI200030663 T SI 200030663T SI 200030663 T SI200030663 T SI 200030663T SI 1150960 T1 SI1150960 T1 SI 1150960T1
- Authority
- SI
- Slovenia
- Prior art keywords
- celecoxib
- crystalline forms
- cyclooxygenase
- compound
- compositions
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A61K9/2022—Organic macromolecular compounds
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- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
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- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
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- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
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- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
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- Public Health (AREA)
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- General Health & Medical Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Virology (AREA)
- Ophthalmology & Optometry (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Biophysics (AREA)
- Pain & Pain Management (AREA)
- Optics & Photonics (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
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- Psychiatry (AREA)
- Addiction (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16985699P | 1999-12-08 | 1999-12-08 | |
EP00983865A EP1150960B1 (de) | 1999-12-08 | 2000-12-01 | Polymorphische kristalline formen von celekoxib |
PCT/US2000/032760 WO2001042222A1 (en) | 1999-12-08 | 2000-12-01 | Polymorphic crystalline forms of celecoxib |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1150960T1 true SI1150960T1 (de) | 2005-08-31 |
Family
ID=46125623
Family Applications (1)
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SI200030663T SI1150960T1 (de) | 1999-12-08 | 2000-12-01 |
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US (1) | US7476744B2 (de) |
EP (2) | EP1528058A1 (de) |
JP (1) | JP2003516394A (de) |
AT (1) | ATE288897T1 (de) |
AU (1) | AU750978B2 (de) |
BR (1) | BR0008088A (de) |
CA (1) | CA2362675A1 (de) |
CY (1) | CY1106307T1 (de) |
CZ (1) | CZ20013210A3 (de) |
DE (1) | DE60018040T2 (de) |
DK (1) | DK1150960T3 (de) |
DZ (1) | DZ3140A1 (de) |
EA (1) | EA003464B1 (de) |
EE (1) | EE200100419A (de) |
GE (1) | GEP20043180B (de) |
HK (1) | HK1055297A1 (de) |
HR (1) | HRP20010589A2 (de) |
IL (1) | IL144799A (de) |
IS (1) | IS6042A (de) |
MX (1) | MXPA01008161A (de) |
NO (1) | NO321062B1 (de) |
NZ (1) | NZ514059A (de) |
PL (1) | PL349224A1 (de) |
SI (1) | SI1150960T1 (de) |
SK (1) | SK11522001A3 (de) |
UA (1) | UA74539C2 (de) |
WO (1) | WO2001042222A1 (de) |
ZA (1) | ZA200207445B (de) |
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EP1833476A1 (de) | 2004-11-23 | 2007-09-19 | PLIVA HRVATSKA d.o.o. | Pharmazeutische zusammensetzung von celecoxib mit verlängerter freisetzung |
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CN102089051A (zh) * | 2008-07-11 | 2011-06-08 | 巴斯夫欧洲公司 | 作为形态学改变剂的两亲性蛋白质 |
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2000
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- 2000-12-01 BR BR0008088-8A patent/BR0008088A/pt not_active Application Discontinuation
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- 2000-12-01 MX MXPA01008161A patent/MXPA01008161A/es not_active IP Right Cessation
- 2000-12-01 EA EA200100874A patent/EA003464B1/ru not_active IP Right Cessation
- 2000-12-01 SI SI200030663T patent/SI1150960T1/xx unknown
- 2000-12-01 DZ DZ003140A patent/DZ3140A1/xx active
- 2000-12-01 CA CA002362675A patent/CA2362675A1/en not_active Abandoned
- 2000-12-01 DE DE60018040T patent/DE60018040T2/de not_active Expired - Fee Related
- 2000-12-01 NZ NZ514059A patent/NZ514059A/xx unknown
- 2000-12-01 SK SK1152-2001A patent/SK11522001A3/sk unknown
- 2000-12-01 WO PCT/US2000/032760 patent/WO2001042222A1/en active IP Right Grant
- 2000-12-01 DK DK00983865T patent/DK1150960T3/da active
- 2000-12-01 US US09/728,040 patent/US7476744B2/en not_active Expired - Fee Related
- 2000-12-01 JP JP2001543523A patent/JP2003516394A/ja not_active Withdrawn
- 2000-12-01 EP EP05002575A patent/EP1528058A1/de not_active Withdrawn
- 2000-12-01 GE GEAP20006102A patent/GEP20043180B/en unknown
- 2000-12-01 EP EP00983865A patent/EP1150960B1/de not_active Expired - Lifetime
- 2000-12-01 AT AT00983865T patent/ATE288897T1/de not_active IP Right Cessation
- 2000-12-01 AU AU20571/01A patent/AU750978B2/en not_active Ceased
- 2000-12-01 PL PL00349224A patent/PL349224A1/xx not_active Application Discontinuation
- 2000-12-01 EE EEP200100419A patent/EE200100419A/xx unknown
- 2000-12-06 CZ CZ20013210A patent/CZ20013210A3/cs unknown
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2001
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- 2001-08-08 NO NO20013868A patent/NO321062B1/no unknown
- 2001-08-09 HR HR20010589A patent/HRP20010589A2/hr not_active Application Discontinuation
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2002
- 2002-09-17 ZA ZA200207445A patent/ZA200207445B/en unknown
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2003
- 2003-10-16 HK HK03107491A patent/HK1055297A1/xx not_active IP Right Cessation
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