SI1078001T1 - Il-6-antagonisticni peptidi - Google Patents

Il-6-antagonisticni peptidi

Info

Publication number
SI1078001T1
SI1078001T1 SI9930940T SI9930940T SI1078001T1 SI 1078001 T1 SI1078001 T1 SI 1078001T1 SI 9930940 T SI9930940 T SI 9930940T SI 9930940 T SI9930940 T SI 9930940T SI 1078001 T1 SI1078001 T1 SI 1078001T1
Authority
SI
Slovenia
Prior art keywords
seq
present
antagonist peptides
peptide
peptides
Prior art date
Application number
SI9930940T
Other languages
English (en)
Slovenian (sl)
Inventor
Ottaviano Serlupi-Crescenzi
Alessandro Bressan
Pietra Linda Della
Anna Rita Pezzotti
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of SI1078001T1 publication Critical patent/SI1078001T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SI9930940T 1998-05-18 1999-05-18 Il-6-antagonisticni peptidi SI1078001T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98108997A EP0972780A1 (en) 1998-05-18 1998-05-18 Il-6 antagonist peptides
EP99926326A EP1078001B1 (en) 1998-05-18 1999-05-18 Il-6 antagonist peptides
PCT/EP1999/003421 WO1999060013A2 (en) 1998-05-18 1999-05-18 Il-6 antagonist peptides

Publications (1)

Publication Number Publication Date
SI1078001T1 true SI1078001T1 (sl) 2007-04-30

Family

ID=8231951

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930940T SI1078001T1 (sl) 1998-05-18 1999-05-18 Il-6-antagonisticni peptidi

Country Status (14)

Country Link
US (2) US6599875B1 (enExample)
EP (2) EP0972780A1 (enExample)
JP (1) JP4468578B2 (enExample)
AT (1) ATE347563T1 (enExample)
AU (1) AU749616B2 (enExample)
CA (2) CA2690399C (enExample)
CY (1) CY1105865T1 (enExample)
DE (1) DE69934308T2 (enExample)
DK (1) DK1078001T3 (enExample)
ES (1) ES2273492T3 (enExample)
IL (2) IL139575A0 (enExample)
PT (1) PT1078001E (enExample)
SI (1) SI1078001T1 (enExample)
WO (1) WO1999060013A2 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0972780A1 (en) * 1998-05-18 2000-01-19 Applied Research Systems ARS Holding N.V. Il-6 antagonist peptides
DK1783222T3 (da) 1998-10-23 2012-07-09 Kirin Amgen Inc Dimere trombopoietiske peptidomimetika, der binder til MPL-receptor og har trombopoietisk aktivitet
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
EP1773400A2 (en) 2004-07-08 2007-04-18 Amgen Inc. Therapeutic peptides
US20070036788A1 (en) * 2004-09-22 2007-02-15 Ahmed Sheriff Use of a compound for reducing the biological effectiveness of il-6
MX2007003320A (es) 2004-09-24 2007-05-18 Amgen Inc Moleculas fc modificadas.
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
WO2007116962A1 (ja) 2006-04-07 2007-10-18 Osaka University 筋再生促進剤
US9283260B2 (en) 2006-04-21 2016-03-15 Amgen Inc. Lyophilized therapeutic peptibody formulations
ES2564392T3 (es) 2007-01-23 2016-03-22 Shinshu University Inhibidores de IL-6 para el tratamiento de rechazo crónico
KR101665729B1 (ko) 2008-06-05 2016-10-12 국립연구개발법인 고쿠리츠간켄큐센터 신경침윤 억제제
KR20110112307A (ko) 2008-11-25 2011-10-12 앨더 바이오파마슈티컬즈, 인코포레이티드 알부민을 상승시키고 및／또는 ｃｒｐ를 낮추는 ｉｌ­６의 길항제
PL2578231T3 (pl) 2010-05-28 2023-01-16 Chugai Seiyaku Kabushiki Kaisha Środek wzmacniający przeciwnowotworową odpowiedź limfocytów t
CA2818813C (en) 2010-11-23 2020-10-06 Alder Biopharmaceuticals, Inc. Anti-il-6 antibodies for the treatment of oral mucositis
WO2015089217A2 (en) 2013-12-10 2015-06-18 Bionz, Llc Methods of developing selective peptide antagonists
ES2778053T3 (es) * 2011-01-18 2020-08-07 Bioniz Llc Composiciones para modular la actividad de la citocina gamma-c
US9327023B2 (en) 2011-10-25 2016-05-03 The Regents Of The University Of Michigan HER2 targeting agent treatment in non-HER2-amplified cancers having HER2 expressing cancer stem cells
CN103923182A (zh) * 2014-01-17 2014-07-16 南通诚信氨基酸有限公司 白介素-6多肽抑制剂及其应用
KR102654684B1 (ko) 2015-10-09 2024-04-04 바이오니즈 테라퓨틱스, 아이엔씨. 감마-ｃ-사이토카인 활성의 조정
EP3620531A4 (en) 2017-05-02 2021-03-17 National Center of Neurology and Psychiatry METHOD OF PREDICTION AND EVALUATION OF THERAPEUTIC EFFECT IN DISEASES RELATING TO IL-6 AND NEUTROPHILS
WO2019078344A1 (ja) 2017-10-20 2019-04-25 学校法人兵庫医科大学 抗ｉｌ－６受容体抗体を含有する術後の癒着を抑制するための医薬組成物
EP3947737A2 (en) 2019-04-02 2022-02-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods of predicting and preventing cancer in patients having premalignant lesions
US12030936B2 (en) 2019-05-03 2024-07-09 Bioniz Therapeutics, Inc. Modulating the effects of gamma-c-cytokine signaling for the treatment of alopecia and alopecia associated disorders
CN116003530B (zh) * 2022-12-27 2023-12-15 西湖大学 一种针对白细胞介素-6的d-蛋白抑制剂及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4420782C1 (de) * 1994-06-15 1995-08-17 Fluegge Ulf Ingo Prof Dr DNA-Sequenz, kodierend einen 2-Oxoglutarat/Malat-Translokator, Plasmide, Bakterien, Hefen und Pflanzen enthaltend diesen Transporter
JPH10506463A (ja) * 1994-09-21 1998-06-23 サイトーゲン コーポレーション ペプチドライブラリー由来の抗原結合性ペプチド（アブチド）
WO1996023899A1 (en) * 1995-02-01 1996-08-08 University Of Massachusetts Medical Center Methods of selecting a random peptide that binds to a target protein
US6004813A (en) * 1995-05-11 1999-12-21 Applied Research Systems Ars Holding N.V. Il-6 activity inhibitor
AU6731896A (en) * 1995-07-17 1997-02-18 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Cyclitol
WO1997013781A2 (en) * 1995-09-28 1997-04-17 Yeda Research And Development Co. Ltd. Synthetic peptides that inhibit il-6 activity
WO1997048728A1 (en) * 1996-06-20 1997-12-24 Koster, Henk, Wilhelmus Il-6 and il-6-receptor derived peptides having il-6 antagonistic or agonistic activity
EP0972780A1 (en) * 1998-05-18 2000-01-19 Applied Research Systems ARS Holding N.V. Il-6 antagonist peptides

Also Published As

Publication number Publication date
US6838433B2 (en) 2005-01-04
EP1078001B1 (en) 2006-12-06
DK1078001T3 (da) 2007-02-19
CY1105865T1 (el) 2011-02-02
IL139575A (en) 2008-03-20
JP4468578B2 (ja) 2010-05-26
CA2690399C (en) 2015-01-20
JP2002527354A (ja) 2002-08-27
WO1999060013A3 (en) 2000-03-09
DE69934308T2 (de) 2007-03-29
CA2690399A1 (en) 1999-11-25
US6599875B1 (en) 2003-07-29
CA2332817C (en) 2010-08-31
EP1078001A2 (en) 2001-02-28
IL139575A0 (en) 2002-02-10
PT1078001E (pt) 2007-01-31
AU4362799A (en) 1999-12-06
CA2332817A1 (en) 1999-11-25
US20030186876A1 (en) 2003-10-02
DE69934308D1 (de) 2007-01-18
EP0972780A1 (en) 2000-01-19
ATE347563T1 (de) 2006-12-15
AU749616B2 (en) 2002-06-27
WO1999060013A2 (en) 1999-11-25
ES2273492T3 (es) 2007-05-01

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