SI1073456T1 - Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje - Google Patents

Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje

Info

Publication number
SI1073456T1
SI1073456T1 SI9930826T SI9930826T SI1073456T1 SI 1073456 T1 SI1073456 T1 SI 1073456T1 SI 9930826 T SI9930826 T SI 9930826T SI 9930826 T SI9930826 T SI 9930826T SI 1073456 T1 SI1073456 T1 SI 1073456T1
Authority
SI
Slovenia
Prior art keywords
osteoprotegerin
prevention
treatment
cardiovascular diseases
opg
Prior art date
Application number
SI9930826T
Other languages
English (en)
Slovenian (sl)
Inventor
Scott Simonet
Ildiko Sarosi
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SI1073456T1 publication Critical patent/SI1073456T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI9930826T 1998-04-23 1999-04-21 Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje SI1073456T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/064,832 US6790823B1 (en) 1998-04-23 1998-04-23 Compositions and methods for the prevention and treatment of cardiovascular diseases
PCT/US1999/008793 WO1999053942A1 (en) 1998-04-23 1999-04-21 Compositions comprising osteoprotegerin for the prevention and treatment of cardiovascular diseases

Publications (1)

Publication Number Publication Date
SI1073456T1 true SI1073456T1 (sl) 2005-12-31

Family

ID=22058524

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930826T SI1073456T1 (sl) 1998-04-23 1999-04-21 Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje

Country Status (11)

Country Link
US (1) US6790823B1 (enExample)
EP (1) EP1073456B1 (enExample)
JP (1) JP4776774B2 (enExample)
AT (1) ATE303817T1 (enExample)
AU (1) AU757806B2 (enExample)
CA (1) CA2325360C (enExample)
DE (1) DE69927147T2 (enExample)
DK (1) DK1073456T3 (enExample)
ES (1) ES2248998T3 (enExample)
SI (1) SI1073456T1 (enExample)
WO (1) WO1999053942A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117175A (en) 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
WO1998028424A2 (en) 1996-12-23 1998-07-02 Immunex Corporation Receptor activator of nf-kappa b, receptor is member of tnf receptor superfamily
NZ332995A (en) 1997-04-15 2000-07-28 Snow Brand Milk Products Co Ltd A protein which binds to osteoclastogenesis inhibitory factor (OCIF)
US6316408B1 (en) 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
BR9808545A (pt) 1997-04-16 2000-05-23 Amgen Inc ácido nucleico isolado, vetor de expressão, célula hospedeira, processos para produzir uma proteìna de ligação da osteoprotegerina, para detectar a presença de uma proteìna de ligação à osteoprotegerina em uma amostra biológica, para avaliar a capacidade de um composto candidato de ligar-se a uma proteìna de ligação da osteoprotegerina e de um composto de teste para aumentar ou reduzir a ligação da proteìna de ligação da osteoprotegerina a odar, para regular a expressão de uma proteìna de ligação da osteoprotegerina em um animal e para prevenir ou tratar de doença óssea em um mamìfero, polipeptìdeo, protéina de ligação da osteroprotegerina purificada e isolada, ou seu fragmento, análogo ou derivado, e, anticorpo ou seu fragmento
US6878811B1 (en) * 1998-04-23 2005-04-12 Ajinomoto Co., Inc. Substance with antithrombotic activity and method for detecting glycokallidin
ATE412746T1 (de) 1998-05-14 2008-11-15 Immunex Corp Verfahren zur hemmung der wirkung der osteoklasten
RU2324705C2 (ru) * 2001-04-03 2008-05-20 Сосьете Де Продюи Нестле С.А. Остеопротегерин, применение его для изготовления фармацевтической композиции (варианты) и получения пищевого продукта (варианты) и корма для животных, пищевой продукт, корм для животных и фармацевтическая композиция для профилактики или лечения расстройств, связанных с костным ремоделированием, и/или иммунных расстройств
US7198798B2 (en) * 2001-05-10 2007-04-03 University Of Washington Methods and devices for promoting endothelial morphogenesis
DK1572874T3 (da) 2001-05-25 2013-12-16 Human Genome Sciences Inc Antistoffer, der immunospecifikt binder til TRAIL receptorer
US8649843B2 (en) * 2001-11-24 2014-02-11 Ben A. Arnold Automated calcium scoring of the aorta
US7718776B2 (en) 2002-04-05 2010-05-18 Amgen Inc. Human anti-OPGL neutralizing antibodies as selective OPGL pathway inhibitors
US7585840B2 (en) 2002-04-10 2009-09-08 Merck Serono S.A. Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease
CN1658895A (zh) * 2002-04-10 2005-08-24 应用研究系统Ars股份公司 护骨素在治疗和／或预防纤维变性疾病中的应用
WO2006047419A2 (en) 2004-10-25 2006-05-04 Intezyne Technologies, Incorporated Heterobifunctional poly(ethylene glycol) and uses thereof
WO2006074202A2 (en) 2005-01-04 2006-07-13 Intezyne Technologies, Incorporated Synthesis of hybrid block copolymers and uses thereof
US7561727B2 (en) * 2005-06-02 2009-07-14 Nordic Bioscience Imaging A/S Method of deriving a quantitative measure of a degree of calcification of an aorta
US7463758B2 (en) * 2005-06-02 2008-12-09 Nordio Bioscience A/S Method of deriving a quantitative measure of a degree of calcification of an aorta
EP2433644A1 (en) * 2010-09-22 2012-03-28 IMBA-Institut für Molekulare Biotechnologie GmbH Breast cancer therapeutics
FR2970870A1 (fr) * 2011-01-31 2012-08-03 Centre Nat Rech Scient Modulation de la proliferation des cellules epitheliales de l'unite epidermo-pilo-sebacee via rank

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
JP2877509B2 (ja) 1989-05-19 1999-03-31 アムジエン・インコーポレーテツド メタロプロテイナーゼ阻害剤
US5580722A (en) * 1989-07-18 1996-12-03 Oncogene Science, Inc. Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease
US6369027B1 (en) 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin

Also Published As

Publication number Publication date
DE69927147T2 (de) 2006-01-26
ES2248998T3 (es) 2006-03-16
WO1999053942A8 (en) 1999-12-02
JP4776774B2 (ja) 2011-09-21
US6790823B1 (en) 2004-09-14
CA2325360A1 (en) 1999-10-28
AU757806B2 (en) 2003-03-06
ATE303817T1 (de) 2005-09-15
AU3660599A (en) 1999-11-08
EP1073456A1 (en) 2001-02-07
DK1073456T3 (da) 2005-10-24
DE69927147D1 (de) 2005-10-13
CA2325360C (en) 2008-11-04
EP1073456B1 (en) 2005-09-07
JP2002512199A (ja) 2002-04-23
WO1999053942A1 (en) 1999-10-28

Similar Documents

Publication Publication Date Title
SI1073456T1 (sl) Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje
YU37602A (sh) Derivat pirolidinacetamida sam ili u kombinaciji za tretman poremećaja cns
EP1021177A4 (en) COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF VASCULAR DEGENERATIVE DISEASES
IL161052A (en) Amionogenic Preparations for the Prevention and Treatment of Inflammatory Disease
TWI265808B (en) Valdecoxib compositions
AU3632497A (en) Use of the chelating agent clioquinol for the manufacture of a pharmaceutical composition for the treatment of alzheimer's disease
BR9807577A (pt) Método para prevenir e retardar o inìcio da doença de alzheimer e sua composição
CA2289717A1 (en) Novel therapy for constipation
PL329940A1 (en) Compositions for once-a-day administration for use in treating diseases involving mediator effect of cyclooxygenase-2
AU7916798A (en) Pharmaceutical compositions of flurbiprofen and burn-masking agent for treating sore throat
WO1999044608A8 (en) New use
EP1119255A4 (en) NEW COMPOSITIONS AND METHOD FOR THE PREVENTION AND TREATMENT OF PROTOCOL DISEASES
AU6281599A (en) Alternate day administration of copolymer 1 for treating autoimmune diseases
AU2300001A (en) Pharmaceutical compositions useful in the prevention and treatment of beta-amyloid protein-induced disease
AU2001257406A1 (en) Methods and compositions for the diagnosis and treatment of cardiovascular and tumorigenic disease using 4941
PL338673A1 (en) Application of fanquinone in treating alzheimer disease
GB9907571D0 (en) Compounds
CA2433785A1 (en) Pharmaceutical compositions which inhibit vascular proliferation and method of use thereof
AU4228000A (en) Methods and compositions for the treatment and prevention of lung disease
AUPP823999A0 (en) A treatment
AU2002215187A1 (en) S-adenosylmethionine and derivatives thereof for the treatment and prevention ofalzheimer's disease
EP0743068A3 (en) Composition for inhibiting bone loss containing vanadyl sulfate
EP0687687A3 (de) Pharmazeutische Zusammensetzung zur Vorbeugung und Behandlung von Blutgerinnungsstörungen
AU4225500A (en) Methods and compositions for the treatment and prevention of lung disease
AU4034800A (en) Novel compositions and methods for prevention and treatment of protozoal disease