SI1073456T1 - Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje - Google Patents

Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje

Info

Publication number
SI1073456T1
SI1073456T1 SI9930826T SI9930826T SI1073456T1 SI 1073456 T1 SI1073456 T1 SI 1073456T1 SI 9930826 T SI9930826 T SI 9930826T SI 9930826 T SI9930826 T SI 9930826T SI 1073456 T1 SI1073456 T1 SI 1073456T1
Authority
SI
Slovenia
Prior art keywords
osteoprotegerin
prevention
treatment
cardiovascular diseases
opg
Prior art date
Application number
SI9930826T
Other languages
English (en)
Inventor
Scott Simonet
Ildiko Sarosi
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of SI1073456T1 publication Critical patent/SI1073456T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SI9930826T 1998-04-23 1999-04-21 Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje SI1073456T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/064,832 US6790823B1 (en) 1998-04-23 1998-04-23 Compositions and methods for the prevention and treatment of cardiovascular diseases
PCT/US1999/008793 WO1999053942A1 (en) 1998-04-23 1999-04-21 Compositions comprising osteoprotegerin for the prevention and treatment of cardiovascular diseases

Publications (1)

Publication Number Publication Date
SI1073456T1 true SI1073456T1 (sl) 2005-12-31

Family

ID=22058524

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930826T SI1073456T1 (sl) 1998-04-23 1999-04-21 Uporaba osteoprotegerina za preventivo pred kardiovaskularnimi boleznimi in za njihovo zdravljenje

Country Status (11)

Country Link
US (1) US6790823B1 (sl)
EP (1) EP1073456B1 (sl)
JP (1) JP4776774B2 (sl)
AT (1) ATE303817T1 (sl)
AU (1) AU757806B2 (sl)
CA (1) CA2325360C (sl)
DE (1) DE69927147T2 (sl)
DK (1) DK1073456T3 (sl)
ES (1) ES2248998T3 (sl)
SI (1) SI1073456T1 (sl)
WO (1) WO1999053942A1 (sl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL117175A (en) 1995-02-20 2005-11-20 Sankyo Co Osteoclastogenesis inhibitory factor protein
DE69738841D1 (de) 1996-12-23 2008-08-28 Immunex Corp Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie
KR100496063B1 (ko) 1997-04-15 2005-06-21 산쿄 가부시키가이샤 신규단백질 및 그 제조방법
US6316408B1 (en) 1997-04-16 2001-11-13 Amgen Inc. Methods of use for osetoprotegerin binding protein receptors
DK0975754T4 (en) 1997-04-16 2016-03-21 Amgen Inc Osteoprotegerin binding proteins and their receptors
US6878811B1 (en) * 1998-04-23 2005-04-12 Ajinomoto Co., Inc. Substance with antithrombotic activity and method for detecting glycokallidin
EP2009025B1 (en) 1998-05-14 2011-07-27 Immunex Corporation Method of inhibiting osteoclast activity
PT1757619E (pt) * 2001-04-03 2010-03-25 Nestle Sa Osteoprotegerina no leite
US7198798B2 (en) * 2001-05-10 2007-04-03 University Of Washington Methods and devices for promoting endothelial morphogenesis
MXPA03010747A (es) 2001-05-25 2004-03-02 Human Genome Sciences Inc Anticuerpos que se unen inmunoespecificamente a receptores de ligando inductor de apoptosis relacionado con factor de necrosis tumoral.
US8649843B2 (en) * 2001-11-24 2014-02-11 Ben A. Arnold Automated calcium scoring of the aorta
JP4761710B2 (ja) 2002-04-05 2011-08-31 アムジェン インコーポレイテッド 選択的ｏｐｇｌ経路インヒビターとしてのヒト抗ｏｐｇｌ中和抗体
KR20040107492A (ko) 2002-04-10 2004-12-20 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. 섬유증 질병의 치료 및/또는 예방을 위한오스테오프로테게린의 용도
US7585840B2 (en) 2002-04-10 2009-09-08 Merck Serono S.A. Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease
US7612153B2 (en) 2004-10-25 2009-11-03 Intezyne Technologies, Inc. Heterobifunctional poly(ethylene glycol) and uses thereof
NZ556290A (en) 2005-01-04 2010-11-26 Intezyne Technologies Inc Synthesis of hybrid block copolymers and uses thereof
US7463758B2 (en) * 2005-06-02 2008-12-09 Nordio Bioscience A/S Method of deriving a quantitative measure of a degree of calcification of an aorta
US7561727B2 (en) * 2005-06-02 2009-07-14 Nordic Bioscience Imaging A/S Method of deriving a quantitative measure of a degree of calcification of an aorta
EP2433644A1 (en) * 2010-09-22 2012-03-28 IMBA-Institut für Molekulare Biotechnologie GmbH Breast cancer therapeutics
FR2970870A1 (fr) * 2011-01-31 2012-08-03 Centre Nat Rech Scient Modulation de la proliferation des cellules epitheliales de l'unite epidermo-pilo-sebacee via rank

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
JP2877509B2 (ja) 1989-05-19 1999-03-31 アムジエン・インコーポレーテツド メタロプロテイナーゼ阻害剤
US5580722A (en) * 1989-07-18 1996-12-03 Oncogene Science, Inc. Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease
US6369027B1 (en) 1995-12-22 2002-04-09 Amgen Inc. Osteoprotegerin

Also Published As

Publication number Publication date
DE69927147D1 (de) 2005-10-13
DE69927147T2 (de) 2006-01-26
JP2002512199A (ja) 2002-04-23
JP4776774B2 (ja) 2011-09-21
DK1073456T3 (da) 2005-10-24
AU757806B2 (en) 2003-03-06
AU3660599A (en) 1999-11-08
CA2325360C (en) 2008-11-04
EP1073456A1 (en) 2001-02-07
EP1073456B1 (en) 2005-09-07
US6790823B1 (en) 2004-09-14
CA2325360A1 (en) 1999-10-28
ES2248998T3 (es) 2006-03-16
WO1999053942A8 (en) 1999-12-02
ATE303817T1 (de) 2005-09-15
WO1999053942A1 (en) 1999-10-28

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