ATE303817T1 - Verwendung von osteoprotegerin zur vorbeugung und behandlung cardiovaskulärer erkrankungen - Google Patents
Verwendung von osteoprotegerin zur vorbeugung und behandlung cardiovaskulärer erkrankungenInfo
- Publication number
- ATE303817T1 ATE303817T1 AT99918766T AT99918766T ATE303817T1 AT E303817 T1 ATE303817 T1 AT E303817T1 AT 99918766 T AT99918766 T AT 99918766T AT 99918766 T AT99918766 T AT 99918766T AT E303817 T1 ATE303817 T1 AT E303817T1
- Authority
- AT
- Austria
- Prior art keywords
- osteoprotegerin
- cardiovascular diseases
- preventing
- treating cardiovascular
- opg
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/064,832 US6790823B1 (en) | 1998-04-23 | 1998-04-23 | Compositions and methods for the prevention and treatment of cardiovascular diseases |
PCT/US1999/008793 WO1999053942A1 (en) | 1998-04-23 | 1999-04-21 | Compositions comprising osteoprotegerin for the prevention and treatment of cardiovascular diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE303817T1 true ATE303817T1 (de) | 2005-09-15 |
Family
ID=22058524
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99918766T ATE303817T1 (de) | 1998-04-23 | 1999-04-21 | Verwendung von osteoprotegerin zur vorbeugung und behandlung cardiovaskulärer erkrankungen |
Country Status (11)
Country | Link |
---|---|
US (1) | US6790823B1 (de) |
EP (1) | EP1073456B1 (de) |
JP (1) | JP4776774B2 (de) |
AT (1) | ATE303817T1 (de) |
AU (1) | AU757806B2 (de) |
CA (1) | CA2325360C (de) |
DE (1) | DE69927147T2 (de) |
DK (1) | DK1073456T3 (de) |
ES (1) | ES2248998T3 (de) |
SI (1) | SI1073456T1 (de) |
WO (1) | WO1999053942A1 (de) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL117175A (en) | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
DE69738841D1 (de) | 1996-12-23 | 2008-08-28 | Immunex Corp | Ligand für rezeptor aktivator of nf-kappa b, ligand ist mitglied der tnf superfamilie |
CN1138786C (zh) | 1997-04-15 | 2004-02-18 | 三共株式会社 | 识别破骨细胞形成抑制因子结合蛋白的抗体及制备和用途 |
US6316408B1 (en) | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
IL132304A0 (en) | 1997-04-16 | 2001-03-19 | Amgen Inc | Osteoprotegerin binding proteins and receptors |
JP4380067B2 (ja) * | 1998-04-23 | 2009-12-09 | 味の素株式会社 | 抗血栓活性物質及びグリコカリシンの検出法 |
EP2009025B1 (de) | 1998-05-14 | 2011-07-27 | Immunex Corporation | Verfahren zur Hemmung der Wirkung der Osteoklasten |
EP1377610A2 (de) * | 2001-04-03 | 2004-01-07 | Société des Produits Nestlé S.A. | Osteoprotegerin in milch |
US7198798B2 (en) * | 2001-05-10 | 2007-04-03 | University Of Washington | Methods and devices for promoting endothelial morphogenesis |
NZ529359A (en) | 2001-05-25 | 2007-04-27 | Human Genome Sciences Inc | Antibodies that immunospecifically bind to a TR4 polypeptide or polypeptide fragment or variant of TR4 and their use in a medicament for treating cancer |
US8649843B2 (en) * | 2001-11-24 | 2014-02-11 | Ben A. Arnold | Automated calcium scoring of the aorta |
CA2481074A1 (en) | 2002-04-05 | 2003-10-23 | Amgen Inc. | Human anti-opgl neutralizing antibodies as selective opgl pathway inhibitors |
US7585840B2 (en) | 2002-04-10 | 2009-09-08 | Merck Serono S.A. | Use of osteoprotegerin for the treatment and/or prevention of fibrotic disease |
CN1658895A (zh) | 2002-04-10 | 2005-08-24 | 应用研究系统Ars股份公司 | 护骨素在治疗和/或预防纤维变性疾病中的应用 |
JP4920593B2 (ja) | 2004-10-25 | 2012-04-18 | インテザイン テクノロジーズ, インコーポレイテッド | ヘテロ二官能性ポリ(エチレングリコール)およびそれらの使用 |
EP2348096A3 (de) | 2005-01-04 | 2011-11-09 | Intezyne Technologies Inc. | Synthese aus Hybridblockcopolymeren und Verwendungen davon. |
US7561727B2 (en) * | 2005-06-02 | 2009-07-14 | Nordic Bioscience Imaging A/S | Method of deriving a quantitative measure of a degree of calcification of an aorta |
US7463758B2 (en) * | 2005-06-02 | 2008-12-09 | Nordio Bioscience A/S | Method of deriving a quantitative measure of a degree of calcification of an aorta |
EP2433644A1 (de) | 2010-09-22 | 2012-03-28 | IMBA-Institut für Molekulare Biotechnologie GmbH | Brustkrebstherapeutika |
FR2970870A1 (fr) * | 2011-01-31 | 2012-08-03 | Centre Nat Rech Scient | Modulation de la proliferation des cellules epitheliales de l'unite epidermo-pilo-sebacee via rank |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
JP2877509B2 (ja) | 1989-05-19 | 1999-03-31 | アムジエン・インコーポレーテツド | メタロプロテイナーゼ阻害剤 |
US5580722A (en) * | 1989-07-18 | 1996-12-03 | Oncogene Science, Inc. | Methods of determining chemicals that modulate transcriptionally expression of genes associated with cardiovascular disease |
US6369027B1 (en) | 1995-12-22 | 2002-04-09 | Amgen Inc. | Osteoprotegerin |
-
1998
- 1998-04-23 US US09/064,832 patent/US6790823B1/en not_active Expired - Fee Related
-
1999
- 1999-04-21 SI SI9930826T patent/SI1073456T1/sl unknown
- 1999-04-21 AU AU36605/99A patent/AU757806B2/en not_active Ceased
- 1999-04-21 WO PCT/US1999/008793 patent/WO1999053942A1/en active IP Right Grant
- 1999-04-21 JP JP2000544345A patent/JP4776774B2/ja not_active Expired - Fee Related
- 1999-04-21 DE DE69927147T patent/DE69927147T2/de not_active Expired - Lifetime
- 1999-04-21 AT AT99918766T patent/ATE303817T1/de active
- 1999-04-21 DK DK99918766T patent/DK1073456T3/da active
- 1999-04-21 EP EP99918766A patent/EP1073456B1/de not_active Expired - Lifetime
- 1999-04-21 ES ES99918766T patent/ES2248998T3/es not_active Expired - Lifetime
- 1999-04-21 CA CA002325360A patent/CA2325360C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6790823B1 (en) | 2004-09-14 |
WO1999053942A8 (en) | 1999-12-02 |
CA2325360A1 (en) | 1999-10-28 |
DE69927147T2 (de) | 2006-01-26 |
CA2325360C (en) | 2008-11-04 |
EP1073456B1 (de) | 2005-09-07 |
JP4776774B2 (ja) | 2011-09-21 |
ES2248998T3 (es) | 2006-03-16 |
AU3660599A (en) | 1999-11-08 |
DE69927147D1 (de) | 2005-10-13 |
EP1073456A1 (de) | 2001-02-07 |
AU757806B2 (en) | 2003-03-06 |
JP2002512199A (ja) | 2002-04-23 |
DK1073456T3 (da) | 2005-10-24 |
WO1999053942A1 (en) | 1999-10-28 |
SI1073456T1 (sl) | 2005-12-31 |
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