SI1047695T1 - Novel bispidine antiarrhythmic compounds - Google Patents
Novel bispidine antiarrhythmic compoundsInfo
- Publication number
- SI1047695T1 SI1047695T1 SI9830633T SI9830633T SI1047695T1 SI 1047695 T1 SI1047695 T1 SI 1047695T1 SI 9830633 T SI9830633 T SI 9830633T SI 9830633 T SI9830633 T SI 9830633T SI 1047695 T1 SI1047695 T1 SI 1047695T1
- Authority
- SI
- Slovenia
- Prior art keywords
- antiarrhythmic compounds
- bispidine
- novel
- novel bispidine
- antiarrhythmic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9704709A SE9704709D0 (sv) | 1997-12-17 | 1997-12-17 | Pharmaceutically active compounds |
| PCT/SE1998/002276 WO1999031100A1 (en) | 1997-12-17 | 1998-12-10 | Novel bispidine antiarrhythmic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1047695T1 true SI1047695T1 (en) | 2004-08-31 |
Family
ID=20409426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9830633T SI1047695T1 (en) | 1997-12-17 | 1998-12-10 | Novel bispidine antiarrhythmic compounds |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6291475B1 (de) |
| EP (1) | EP1047695B1 (de) |
| JP (1) | JP2002508375A (de) |
| KR (1) | KR20010024723A (de) |
| CN (1) | CN1284956A (de) |
| AR (1) | AR017217A1 (de) |
| AT (1) | ATE261964T1 (de) |
| AU (1) | AU1795399A (de) |
| BR (1) | BR9813668A (de) |
| CA (1) | CA2314490A1 (de) |
| DE (1) | DE69822513T2 (de) |
| DK (1) | DK1047695T3 (de) |
| EE (1) | EE200000365A (de) |
| ES (1) | ES2216337T3 (de) |
| HU (1) | HUP0102307A3 (de) |
| ID (1) | ID24638A (de) |
| IL (1) | IL136374A0 (de) |
| IS (1) | IS5522A (de) |
| NO (1) | NO20003137L (de) |
| NZ (1) | NZ504909A (de) |
| PL (1) | PL341388A1 (de) |
| PT (1) | PT1047695E (de) |
| SE (1) | SE9704709D0 (de) |
| SI (1) | SI1047695T1 (de) |
| SK (1) | SK7812000A3 (de) |
| TR (1) | TR200001757T2 (de) |
| WO (1) | WO1999031100A1 (de) |
| ZA (1) | ZA9811130B (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9803517D0 (sv) * | 1998-10-15 | 1998-10-15 | Astra Ab | Pharmaceutical preparation |
| TWI229674B (en) | 1998-12-04 | 2005-03-21 | Astra Pharma Prod | Novel triazolo[4,5-d]pyrimidine compounds, pharmaceutical composition containing the same, their process for preparation and uses |
| SE9902269D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
| SE9902270D0 (sv) | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
| SE9902271D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
| US20050004113A1 (en) * | 1999-06-16 | 2005-01-06 | Astrazeneca Ab | New bispidine compounds useful in the treatment of cardiac arrhythmias |
| US20040229900A1 (en) * | 1999-06-16 | 2004-11-18 | Astrazeneca Ab | Bispidine compounds useful in the treatment of cardiac arrythmias |
| SE9902268D0 (sv) * | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
| US7038054B1 (en) * | 1999-09-03 | 2006-05-02 | Pharmacopeia Drug Discovery, Inc. | Diazabicyclononane scaffold for combinatorial synthesis |
| SE9903759D0 (sv) * | 1999-10-18 | 1999-10-18 | Astra Ab | Pharmaceutically active compounds |
| JP2003516988A (ja) | 1999-12-14 | 2003-05-20 | ニューロサーチ、アクティーゼルスカブ | 新規ヘテロアリール−ジアザビシクロアルカン類 |
| SE9904765D0 (sv) | 1999-12-23 | 1999-12-23 | Astra Ab | Pharmaceutically-useful compounds |
| AR030302A1 (es) * | 2000-07-07 | 2003-08-20 | Astrazeneca Ab | Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios |
| SE0002603D0 (sv) * | 2000-07-07 | 2000-07-07 | Astrazeneca Ab | New compounds |
| US6808924B1 (en) | 2000-07-11 | 2004-10-26 | Claudia Lanari | Mouse mammary tumor lines expressing estrogen and progesterone receptors |
| AR030756A1 (es) | 2000-10-02 | 2003-09-03 | Astrazeneca Ab | Compuesto de oxabispidina util en el tratamiento de arritmias cardiacas |
| SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
| SE0100326D0 (sv) | 2001-02-02 | 2001-02-02 | Astrazeneca Ab | New compounds |
| SE0101329D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | Pharmaceutical formulation |
| SE0101324D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New process |
| SE0101327D0 (sv) * | 2001-04-12 | 2001-04-12 | Astrazeneca Ab | New crystalline forms |
| TWI259836B (en) * | 2001-04-12 | 2006-08-11 | Astrazeneca Ab | Modified release formulation suitable for antiarrhythmic compounds |
| JP2004538268A (ja) * | 2001-06-01 | 2004-12-24 | ニューロサーチ、アクティーゼルスカブ | Ｃｎｓ−モジュレーターとしての新規ヘテロアリール−ジアザビシクロアルカン類 |
| TW200418468A (en) * | 2002-11-18 | 2004-10-01 | Solvay Pharm Gmbh | Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events |
| EP1730145A1 (de) * | 2004-03-22 | 2006-12-13 | Boehringer Ingelheim Pharmaceuticals Inc. | Alpha-trifluormethylalkohole oder -amine als glucocorticoidmimetika |
| SE0401539D0 (sv) | 2004-06-15 | 2004-06-15 | Astrazeneca Ab | New compounds |
| SE0401540D0 (sv) | 2004-06-15 | 2004-06-15 | Astrazeneca Ab | New compounds |
| WO2006135316A1 (en) | 2005-06-13 | 2006-12-21 | Astrazeneca Ab | New oxabispidine compounds for the treatment of cardiac arrhythmias |
| CN102485725B (zh) * | 2010-12-02 | 2015-07-22 | 武汉药明康德新药开发有限公司 | 一种双氮杂环桥环类药物模板及其制备方法和应用 |
| WO2012172043A1 (en) | 2011-06-15 | 2012-12-20 | Laboratoire Biodim | Purine derivatives and their use as pharmaceuticals for prevention or treatment of bacterial infections |
| CN102875550B (zh) * | 2011-07-12 | 2016-01-06 | 常州合全药业有限公司 | 1,3,7-三取代-3,7-二氮杂双环[3,3,1]壬烷衍生物及制备方法 |
| CN104151277A (zh) * | 2014-06-30 | 2014-11-19 | 北京万全德众医药生物技术有限公司 | 盐酸决奈达隆一种氧化杂质的制备方法 |
| CN113683585B (zh) * | 2021-09-26 | 2023-07-11 | 齐鲁工业大学 | 一种含环氧基邻苯二甲腈单体的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2428792A1 (de) | 1974-06-14 | 1976-01-02 | Knoll Ag | Neue antiarrhythmika |
| DE3112055A1 (de) | 1981-03-27 | 1982-10-07 | Basf Ag, 6700 Ludwigshafen | Bispidinderivate, ihre herstellung und diese enthaltende arzneimittel |
| DE3234697A1 (de) | 1982-09-18 | 1984-03-22 | Kali-Chemie Pharma Gmbh, 3000 Hannover | Neue diazabicyclo-(3,3,1)-nonane |
| PT88381B (pt) * | 1987-09-09 | 1995-07-06 | Kali Chemie Pharma Gmbh | Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos |
| DE3732094A1 (de) * | 1987-09-24 | 1989-04-06 | Basf Ag | Bispidinderivate als klasse iii-antiarrhythmika |
| US5110933A (en) | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
| US5468858A (en) | 1993-10-28 | 1995-11-21 | The Board Of Regents Of Oklahoma State University Physical Sciences | N-alkyl and n-acyl derivatives of 3,7-diazabicyclo-[3.3.1]nonanes and selected salts thereof as multi-class antiarrhythmic agents |
| FR2713081B1 (fr) | 1993-11-29 | 1996-01-12 | Celsa Lg | Filtre sanguin perfectionné à deux séries de pattes en pétales. |
-
1997
- 1997-12-17 SE SE9704709A patent/SE9704709D0/xx unknown
-
1998
- 1998-12-04 ZA ZA9811130A patent/ZA9811130B/xx unknown
- 1998-12-10 DE DE69822513T patent/DE69822513T2/de not_active Expired - Fee Related
- 1998-12-10 HU HU0102307A patent/HUP0102307A3/hu unknown
- 1998-12-10 US US09/214,756 patent/US6291475B1/en not_active Expired - Fee Related
- 1998-12-10 DK DK98962796T patent/DK1047695T3/da active
- 1998-12-10 WO PCT/SE1998/002276 patent/WO1999031100A1/en active IP Right Grant
- 1998-12-10 AU AU17953/99A patent/AU1795399A/en not_active Abandoned
- 1998-12-10 PL PL98341388A patent/PL341388A1/xx unknown
- 1998-12-10 EP EP98962796A patent/EP1047695B1/de not_active Expired - Lifetime
- 1998-12-10 KR KR1020007006585A patent/KR20010024723A/ko not_active Application Discontinuation
- 1998-12-10 SK SK781-2000A patent/SK7812000A3/sk unknown
- 1998-12-10 BR BR9813668-2A patent/BR9813668A/pt not_active IP Right Cessation
- 1998-12-10 ID IDW20001081A patent/ID24638A/id unknown
- 1998-12-10 PT PT98962796T patent/PT1047695E/pt unknown
- 1998-12-10 CA CA002314490A patent/CA2314490A1/en not_active Abandoned
- 1998-12-10 CN CN98813573A patent/CN1284956A/zh active Pending
- 1998-12-10 AT AT98962796T patent/ATE261964T1/de not_active IP Right Cessation
- 1998-12-10 IL IL13637498A patent/IL136374A0/xx unknown
- 1998-12-10 SI SI9830633T patent/SI1047695T1/xx unknown
- 1998-12-10 EE EEP200000365A patent/EE200000365A/xx unknown
- 1998-12-10 NZ NZ504909A patent/NZ504909A/en unknown
- 1998-12-10 TR TR2000/01757T patent/TR200001757T2/xx unknown
- 1998-12-10 ES ES98962796T patent/ES2216337T3/es not_active Expired - Lifetime
- 1998-12-10 JP JP2000539024A patent/JP2002508375A/ja active Pending
- 1998-12-16 AR ARP980106399A patent/AR017217A1/es unknown
-
2000
- 2000-06-02 IS IS5522A patent/IS5522A/is unknown
- 2000-06-16 NO NO20003137A patent/NO20003137L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20010024723A (ko) | 2001-03-26 |
| CA2314490A1 (en) | 1999-06-24 |
| DE69822513D1 (de) | 2004-04-22 |
| DK1047695T3 (da) | 2004-06-28 |
| HUP0102307A2 (hu) | 2001-12-28 |
| SE9704709D0 (sv) | 1997-12-17 |
| IS5522A (is) | 2000-06-02 |
| ATE261964T1 (de) | 2004-04-15 |
| DE69822513T2 (de) | 2005-03-10 |
| NO20003137D0 (no) | 2000-06-16 |
| NZ504909A (en) | 2001-11-30 |
| ES2216337T3 (es) | 2004-10-16 |
| CN1284956A (zh) | 2001-02-21 |
| SK7812000A3 (en) | 2001-05-10 |
| EE200000365A (et) | 2001-10-15 |
| PL341388A1 (en) | 2001-04-09 |
| EP1047695B1 (de) | 2004-03-17 |
| BR9813668A (pt) | 2000-10-17 |
| TR200001757T2 (tr) | 2000-09-21 |
| IL136374A0 (en) | 2001-06-14 |
| NO20003137L (no) | 2000-08-17 |
| HUP0102307A3 (en) | 2002-02-28 |
| JP2002508375A (ja) | 2002-03-19 |
| AR017217A1 (es) | 2001-08-22 |
| EP1047695A1 (de) | 2000-11-02 |
| WO1999031100A1 (en) | 1999-06-24 |
| ID24638A (id) | 2000-07-27 |
| PT1047695E (pt) | 2004-07-30 |
| US6291475B1 (en) | 2001-09-18 |
| ZA9811130B (en) | 1999-06-17 |
| AU1795399A (en) | 1999-07-05 |
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