SI0870014T1 - Aldolazno katalitično protitelo - Google Patents

Aldolazno katalitično protitelo

Info

Publication number
SI0870014T1
SI0870014T1 SI9630754T SI9630754T SI0870014T1 SI 0870014 T1 SI0870014 T1 SI 0870014T1 SI 9630754 T SI9630754 T SI 9630754T SI 9630754 T SI9630754 T SI 9630754T SI 0870014 T1 SI0870014 T1 SI 0870014T1
Authority
SI
Slovenia
Prior art keywords
antibody
catalytic antibody
antibodies
catalytic
aldolase catalytic
Prior art date
Application number
SI9630754T
Other languages
English (en)
Inventor
Carlos F Barbas Iii
Richard A Lerner
Juergen Wagner
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of SI0870014T1 publication Critical patent/SI0870014T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/901—Antibodies with enzymatic activity; e.g. abzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SI9630754T 1995-12-15 1996-12-16 Aldolazno katalitično protitelo SI0870014T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/573,415 US5733757A (en) 1995-12-15 1995-12-15 Aldolase catalytic antibody
PCT/US1996/020052 WO1997021803A1 (en) 1995-12-15 1996-12-16 Aldolase catalytic antibody
EP96943772A EP0870014B9 (en) 1995-12-15 1996-12-16 Aldolase catalytic antibody

Publications (1)

Publication Number Publication Date
SI0870014T1 true SI0870014T1 (sl) 2007-08-31

Family

ID=24291910

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9630754T SI0870014T1 (sl) 1995-12-15 1996-12-16 Aldolazno katalitično protitelo

Country Status (12)

Country Link
US (3) US5733757A (sl)
EP (1) EP0870014B9 (sl)
JP (1) JP3996642B2 (sl)
AT (1) ATE354644T1 (sl)
AU (1) AU729055B2 (sl)
CA (1) CA2239167C (sl)
DE (1) DE69636923T2 (sl)
DK (1) DK0870014T3 (sl)
ES (1) ES2283009T3 (sl)
PT (1) PT870014E (sl)
SI (1) SI0870014T1 (sl)
WO (1) WO1997021803A1 (sl)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1038018A4 (en) * 1997-12-18 2004-10-13 Scripps Research Inst ALDOL CONDENSATIONS USED WITH CATALYTIC ANTIBODIES
US6326176B1 (en) 1997-12-18 2001-12-04 The Scripps Research Institute Aldol condensations by catalytic antibodies
US6440710B1 (en) 1998-12-10 2002-08-27 The Scripps Research Institute Antibody-catalyzed deuteration, tritiation, dedeuteration or detritiation of carbonyl compounds
US6294374B1 (en) * 1999-10-08 2001-09-25 The Scripps Research Institute Use of catalytic antibodies for synthesizing epothilone
US20040048312A1 (en) * 2002-04-12 2004-03-11 Ronghao Li Antibodies that bind to integrin alpha-v-beta-6 and methods of use thereof
AU2006235781B2 (en) * 2004-04-27 2008-04-03 Teddy Yeung Man Lo LED illuminated glow stick
EP2292248A3 (en) 2005-03-03 2011-06-29 CovX Technologies Ireland Limited Anti-angiogenic compounds
NZ576751A (en) * 2006-11-10 2011-10-28 Covx Technologies Ireland Ltd Anti-angiogenic compounds
US20090098130A1 (en) * 2007-01-05 2009-04-16 Bradshaw Curt W Glucagon-like protein-1 receptor (glp-1r) agonist compounds
JP6035009B2 (ja) 2007-08-22 2016-11-30 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 活性化可能な結合ポリペプチドおよびその同定方法ならびに使用
US8637435B2 (en) * 2007-11-16 2014-01-28 Merck Sharp & Dohme Corp. Eukaryotic cell display systems
US8340951B2 (en) * 2007-12-13 2012-12-25 University Of Washington Synthetic enzymes derived from computational design
EP2263089B1 (en) 2008-03-03 2015-01-28 GlycoFi, Inc. Surface display of recombinant proteins in lower eukaryotes
US8293714B2 (en) 2008-05-05 2012-10-23 Covx Technology Ireland, Ltd. Anti-angiogenic compounds
US8067339B2 (en) 2008-07-09 2011-11-29 Merck Sharp & Dohme Corp. Surface display of whole antibodies in eukaryotes
EP3543256A1 (en) 2009-01-12 2019-09-25 Cytomx Therapeutics Inc. Modified antibody compositions, methods of making and using thereof
RU2011138951A (ru) 2009-02-23 2013-03-27 Сайтомкс Терапьютикс, Инк. Пропротеины и способы их применения
US20120003695A1 (en) 2009-02-25 2012-01-05 Davidson Robert C Metabolic engineering of a galactose assimilation pathway in the glycoengineered yeast pichia pastoris
US20120148586A1 (en) 2009-08-27 2012-06-14 Joyce Ching Tsu Chou Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
MX2012009802A (es) 2010-02-24 2012-09-12 Merck Sharp & Dohme Metodo para incrementar la ocupacion del sitio de n-glucosilacion en glucoproteinas terapeuticas producidas en pichia pastoris.
RU2012157167A (ru) 2010-07-12 2014-08-20 КовЭкс Текнолоджиз Айэлэнд Лимитед Полифункциональные антительные конъюгаты
WO2012009705A1 (en) 2010-07-15 2012-01-19 Zyngenia, Inc. Ang-2 binding complexes and uses thereof
EP2949338B1 (en) 2010-08-20 2017-10-25 Wyeth LLC Designer osteogenic proteins
US9688735B2 (en) 2010-08-20 2017-06-27 Wyeth Llc Designer osteogenic proteins
SG190082A1 (en) 2010-11-05 2013-06-28 Covx Technologies Ireland Ltd Anti-diabetic compounds
WO2012162561A2 (en) 2011-05-24 2012-11-29 Zyngenia, Inc. Multivalent and monovalent multispecific complexes and their uses
MX2014007500A (es) 2011-12-20 2014-07-28 Pfizer Procesos mejorados para preparar conjugados y enlazadores de peptido.
SG11201402640SA (en) 2011-12-22 2014-10-30 Pfizer Anti-diabetic compounds
US9958437B2 (en) 2012-02-03 2018-05-01 The Governors Of The University Of Alberta Method of quantifying peptide-derivative libraries using phage display
WO2014144600A2 (en) 2013-03-15 2014-09-18 Viktor Roschke Multivalent and monovalent multispecific complexes and their uses
CN113329769A (zh) * 2018-10-11 2021-08-31 斯克里普斯研究学院 具有反应性精氨酸的抗体化合物及相关的抗体药物缀合物

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5571681A (en) * 1994-03-10 1996-11-05 The Scripps Research Institute Chemical event selection by suicide substrate conjugates

Also Published As

Publication number Publication date
ATE354644T1 (de) 2007-03-15
AU729055B2 (en) 2001-01-25
WO1997021803A1 (en) 1997-06-19
JPH11510063A (ja) 1999-09-07
EP0870014A4 (en) 2002-03-13
AU1292397A (en) 1997-07-03
ES2283009T3 (es) 2007-10-16
CA2239167A1 (en) 1997-06-19
DE69636923D1 (de) 2007-04-05
US6368839B1 (en) 2002-04-09
DE69636923T2 (de) 2007-11-08
EP0870014B9 (en) 2007-10-10
JP3996642B2 (ja) 2007-10-24
DK0870014T3 (da) 2007-06-11
EP0870014A1 (en) 1998-10-14
US5985626A (en) 1999-11-16
CA2239167C (en) 2009-09-22
US5733757A (en) 1998-03-31
PT870014E (pt) 2007-05-31
EP0870014B1 (en) 2007-02-21

Similar Documents

Publication Publication Date Title
SI0870014T1 (sl) Aldolazno katalitično protitelo
DK0404097T3 (sl)
HK1023513A1 (en) Compositions comprising conjugates of stable, active, human ob protein with antibody fc chain and methods
MY104946A (en) Antigen antibody conjugate.
GB9206422D0 (en) Antibody preparation
AU563356B2 (en) Conjugate of enzyme and antibody
NO173557C (no) Monoklonalt antistoff, immunogent konjugat, cyklosporin, fremgangsmaate for fremstilling av det monoklonale antistoff samt immunotestsett
EP1181938A3 (en) Rapamycin conjugates and antibodies
EP0521996A4 (en) Catalytic antibody components
CA2348026A1 (en) Antibodies against semp1, methods for their production and uses thereof
DE69412815D1 (de) Künstliche rezeptoren, antikörper und enzyme
WO1995007466A3 (en) Biotin-analog conjugated antibodies for positive cell selection and release
EP0601318A3 (de) Verfahren zur Herstellung von Konjugaten aus einem spezifischen Bindungspartner und einem kohlenhydrathaltigen Protein.
MY103231A (en) Immunoglobulin conjugates
AU2440188A (en) Immunoassays using antigens produced in heterologous organisms
MX9800967A (es) Compuestos quimicos.
MXPA02008247A (es) Conjugado de polisacarido-polipeptido.
AU2002233278A1 (en) Method and use of the cytosolic nadp-dependent malate-decarboxylase isoenzyme for identifying a malignant process, and a suitable test kit
Kovalev et al. Preparation of antibodies against o-aminoazotoluene using chemically and enzymatically synthesized conjugated antigens
CA2559998A1 (en) Rapamycin conjugates and antibodies
MX9802129A (es) Anticuerpo monoclonal br110 y usos del mismo.