EP1038018A4 - Aldol condensations by catalytic antibodies - Google Patents

Aldol condensations by catalytic antibodies

Info

Publication number
EP1038018A4
EP1038018A4 EP98964079A EP98964079A EP1038018A4 EP 1038018 A4 EP1038018 A4 EP 1038018A4 EP 98964079 A EP98964079 A EP 98964079A EP 98964079 A EP98964079 A EP 98964079A EP 1038018 A4 EP1038018 A4 EP 1038018A4
Authority
EP
European Patent Office
Prior art keywords
catalytic antibodies
aldol condensations
condensations
aldol
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98964079A
Other languages
German (de)
French (fr)
Other versions
EP1038018A1 (en
Inventor
Carlos F Barbas Iii
Robert A Lerner
Guofu Zhong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Publication of EP1038018A1 publication Critical patent/EP1038018A1/en
Publication of EP1038018A4 publication Critical patent/EP1038018A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0002—Antibodies with enzymatic activity, e.g. abzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
EP98964079A 1997-12-18 1998-12-18 Aldol condensations by catalytic antibodies Withdrawn EP1038018A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6804997P 1997-12-18 1997-12-18
US68049P 1997-12-18
PCT/US1998/026942 WO1999031263A1 (en) 1997-12-18 1998-12-18 Aldol condensations by catalytic antibodies

Publications (2)

Publication Number Publication Date
EP1038018A1 EP1038018A1 (en) 2000-09-27
EP1038018A4 true EP1038018A4 (en) 2004-10-13

Family

ID=22080105

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98964079A Withdrawn EP1038018A4 (en) 1997-12-18 1998-12-18 Aldol condensations by catalytic antibodies

Country Status (5)

Country Link
EP (1) EP1038018A4 (en)
JP (1) JP2002508188A (en)
AU (1) AU1927799A (en)
CA (1) CA2315260A1 (en)
WO (1) WO1999031263A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2121611B1 (en) 2007-03-19 2015-04-15 DSM IP Assets B.V. UV-filter compounds based on alpha,beta-dihydroxyketones
AU2009234373B2 (en) * 2008-04-09 2015-09-24 Cornell University Coferons and methods of making and using them
US9771345B2 (en) 2009-10-07 2017-09-26 Cornell University Coferons and methods of making and using them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5733757A (en) * 1995-12-15 1998-03-31 The Scripps Research Institute Aldolase catalytic antibody

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HOFFMANN T ET AL: "ALDOLASE ANTIBODIES OF REMARKABLE SCOPE", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 120, 1998, pages 2768 - 2779, XP002922026, ISSN: 0002-7863 *
JACOBSEN J R ET AL: "THE SCOPE OF ANTIBODY CATALYSIS", CURRENT OPINION IN STRUCTURAL BIOLOGY, CURRENT BIOLOGY LTD., LONDON, GB, vol. 5, no. 6, December 1995 (1995-12-01), pages 818 - 824, XP001038699, ISSN: 0959-440X *
REYMOND J-L ET AL: "Catalytic, Enantioselective Aldol Reaction Using Antibodies Against a Quaternary Ammonium Ion with a Primary Amine Cofactor", TETRAHEDRON LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 36, no. 15, 10 April 1995 (1995-04-10), pages 2575 - 2578, XP004028253, ISSN: 0040-4039 *
See also references of WO9931263A1 *

Also Published As

Publication number Publication date
AU1927799A (en) 1999-07-05
JP2002508188A (en) 2002-03-19
WO1999031263A1 (en) 1999-06-24
EP1038018A1 (en) 2000-09-27
CA2315260A1 (en) 1999-06-24

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Legal Events

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