SG70010A1 - Fluorinated vitamin d3 analogs - Google Patents

Fluorinated vitamin d3 analogs

Info

Publication number
SG70010A1
SG70010A1 SG1997001484A SG1997001484A SG70010A1 SG 70010 A1 SG70010 A1 SG 70010A1 SG 1997001484 A SG1997001484 A SG 1997001484A SG 1997001484 A SG1997001484 A SG 1997001484A SG 70010 A1 SG70010 A1 SG 70010A1
Authority
SG
Singapore
Prior art keywords
analogs
fluorinated vitamin
fluorinated
vitamin
Prior art date
Application number
SG1997001484A
Other languages
English (en)
Inventor
Percy Sarwood Manchand
John Joseph Nestor Jr
Milan Radoje Uskokovic
Brian Henry Vickery
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG70010A1 publication Critical patent/SG70010A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SG1997001484A 1996-05-23 1997-05-12 Fluorinated vitamin d3 analogs SG70010A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1821996P 1996-05-23 1996-05-23
US3990197P 1997-03-19 1997-03-19

Publications (1)

Publication Number Publication Date
SG70010A1 true SG70010A1 (en) 2000-01-25

Family

ID=26690870

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1997001484A SG70010A1 (en) 1996-05-23 1997-05-12 Fluorinated vitamin d3 analogs

Country Status (26)

Country Link
EP (1) EP0808832B1 (pt)
JP (1) JP2859248B2 (pt)
KR (1) KR100253961B1 (pt)
CN (1) CN100402497C (pt)
AR (1) AR007776A1 (pt)
AT (1) ATE238278T1 (pt)
AU (1) AU733970B2 (pt)
BR (1) BR9703385A (pt)
CA (1) CA2205315C (pt)
CO (1) CO4940503A1 (pt)
CZ (1) CZ157797A3 (pt)
DE (1) DE69721123T2 (pt)
DK (1) DK0808832T3 (pt)
ES (1) ES2195049T3 (pt)
HR (1) HRP970272A2 (pt)
HU (1) HUP9700928A3 (pt)
IL (1) IL120844A0 (pt)
MA (1) MA24250A1 (pt)
NO (1) NO972278L (pt)
NZ (1) NZ314840A (pt)
PE (1) PE66798A1 (pt)
PL (1) PL320130A1 (pt)
PT (1) PT808832E (pt)
SG (1) SG70010A1 (pt)
TR (1) TR199700416A2 (pt)
YU (1) YU20097A (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6008209A (en) * 1997-04-28 1999-12-28 Hoffmann-La Roche Inc. Method of using vitamin D3 analogs with bis C-20 side chains
DE19935771A1 (de) 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US20030220307A1 (en) * 2000-08-17 2003-11-27 Akira Kawase Remedial agent for osteoporosis
RU2296121C2 (ru) * 2001-09-21 2007-03-27 Ф.Хоффманн-Ля Рош Аг Соединения, способ их получения, способы лечения
CA2476224A1 (en) 2003-09-24 2005-03-24 Bioxell Spa Compound and use in treatment
EP1797033A4 (en) * 2004-09-24 2010-04-28 Bioxell Spa 20-CYCLOALKYL-26,27-ALKYL / HALOGENALKYL-VITAMIN-D3 COMPOUNDS AND METHODS FOR THEIR APPLICATION
JP2008538114A (ja) * 2005-03-23 2008-10-09 ビオクセル エッセ ピ ア ２０−アルキル、ジェミニビタミンｄ３化合物及びその使用方法
JP5738307B2 (ja) 2010-10-25 2015-06-24 帝人ファーマ株式会社 ２３−イン−ビタミンｄ３誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4141746A1 (de) * 1991-12-13 1993-06-17 Schering Ag 20-methyl-substituierte vitamin d-derivate
DE4220757A1 (de) * 1992-06-24 1994-01-05 Schering Ag Derivate in der Vitamin D-Reihe mit Modifikationen in der 20-Position, Verfahren zu ihrer Herstellung, Zwischenprodukte für dieses Verfahren, diese Derivate enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
US5384314B1 (en) * 1994-03-11 1997-08-05 Hoffmann La Roche 1alpha-fluoro-25-hydroxy-16-ene-23-yne-cholecalciferol
AU7295696A (en) * 1995-10-27 1997-05-22 F. Hoffmann-La Roche Ag Pharmaceutical composition for treating osteoporosis

Also Published As

Publication number Publication date
DE69721123D1 (de) 2003-05-28
BR9703385A (pt) 1998-09-15
NO972278L (no) 1997-11-24
PT808832E (pt) 2003-07-31
JP2859248B2 (ja) 1999-02-17
TR199700416A2 (xx) 1997-12-21
DK0808832T3 (da) 2003-08-11
AU2357697A (en) 1997-11-27
AR007776A1 (es) 1999-11-24
CA2205315C (en) 2006-10-24
NZ314840A (en) 1998-11-25
PL320130A1 (en) 1997-11-24
EP0808832A2 (en) 1997-11-26
HUP9700928A3 (en) 1999-07-28
EP0808832B1 (en) 2003-04-23
IL120844A0 (en) 1997-09-30
PE66798A1 (es) 1998-10-22
ATE238278T1 (de) 2003-05-15
NO972278D0 (no) 1997-05-20
KR100253961B1 (ko) 2000-04-15
CZ157797A3 (en) 1997-12-17
JPH1045714A (ja) 1998-02-17
ES2195049T3 (es) 2003-12-01
HRP970272A2 (en) 1998-04-30
CN100402497C (zh) 2008-07-16
KR970074764A (ko) 1997-12-10
CO4940503A1 (es) 2000-07-24
MA24250A1 (fr) 1998-04-01
HU9700928D0 (en) 1997-07-28
DE69721123T2 (de) 2004-01-08
MX9703775A (es) 1998-06-30
YU20097A (sh) 1999-09-27
CA2205315A1 (en) 1997-11-23
AU733970B2 (en) 2001-05-31
EP0808832A3 (en) 1999-02-03
HUP9700928A2 (hu) 1998-01-28
CN1172801A (zh) 1998-02-11

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