SG62385G - Process for the preparation of 2-acyl-1,3,4,6,7,11b-2h-hexahydro-4-pyrazino(2,1-a) isoquinolinones and intermediates - Google Patents
Process for the preparation of 2-acyl-1,3,4,6,7,11b-2h-hexahydro-4-pyrazino(2,1-a) isoquinolinones and intermediatesInfo
- Publication number
- SG62385G SG62385G SG623/85A SG62385A SG62385G SG 62385 G SG62385 G SG 62385G SG 623/85 A SG623/85 A SG 623/85A SG 62385 A SG62385 A SG 62385A SG 62385 G SG62385 G SG 62385G
- Authority
- SG
- Singapore
- Prior art keywords
- acyl
- pyrazino
- hexahydro
- intermediates
- isoquinolinones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8201758A FR2520740A1 (fr) | 1982-01-29 | 1982-01-29 | Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires |
Publications (1)
Publication Number | Publication Date |
---|---|
SG62385G true SG62385G (en) | 1986-11-21 |
Family
ID=9270646
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG623/85A SG62385G (en) | 1982-01-29 | 1985-08-24 | Process for the preparation of 2-acyl-1,3,4,6,7,11b-2h-hexahydro-4-pyrazino(2,1-a) isoquinolinones and intermediates |
Country Status (18)
Country | Link |
---|---|
US (1) | US4523013A (es) |
EP (1) | EP0086678B1 (es) |
JP (1) | JPS58134091A (es) |
KR (1) | KR840003252A (es) |
AT (1) | ATE14126T1 (es) |
CA (1) | CA1202629A (es) |
CS (1) | CS235304B2 (es) |
DE (1) | DE3360328D1 (es) |
DK (1) | DK30183A (es) |
ES (1) | ES8400416A1 (es) |
FI (1) | FI75346C (es) |
FR (1) | FR2520740A1 (es) |
HU (1) | HU187848B (es) |
IL (1) | IL67547A (es) |
NZ (1) | NZ202981A (es) |
OA (1) | OA07301A (es) |
SG (1) | SG62385G (es) |
ZA (1) | ZA83166B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3472678D1 (de) * | 1983-07-18 | 1988-08-18 | Beecham Group Plc | Benzazepine and benzoxazepine derivatives |
GB8509435D0 (en) * | 1985-04-12 | 1985-05-15 | Beecham Group Plc | Intermediates & process |
HU208311B (en) * | 1989-11-02 | 1993-09-28 | Alkaloida Vegyeszeti Gyar | Resolving process for producing enantiomers of 2-/4-(5-trifluoromethyl-2-pyridyloxy)-phenoxy/-propanoic acid |
CN100503582C (zh) * | 2005-03-01 | 2009-06-24 | 江苏工业学院 | 吡喹酮合成工艺 |
WO2012081036A2 (en) * | 2010-12-13 | 2012-06-21 | Sequent Scientific Limited | A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione) |
CN102786519B (zh) * | 2011-05-17 | 2017-04-19 | 中国医学科学院药物研究所 | 吡喹酮晶b型物质及制备方法与在药品和保健品中应用 |
CN102786520A (zh) * | 2011-05-17 | 2012-11-21 | 中国医学科学院药物研究所 | 吡喹酮晶a型物质及制备方法与在药品和保健品中应用 |
WO2013060292A1 (zh) * | 2011-10-26 | 2013-05-02 | 苏州同力生物医药有限公司 | 制备左旋吡喹酮的方法 |
CN115466261A (zh) * | 2022-09-15 | 2022-12-13 | 诚弘制药(威海)有限责任公司 | 一种吡喹酮的新制备方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE624686A (es) * | ||||
US3239582A (en) * | 1958-05-21 | 1966-03-08 | Dow Chemical Co | Blend of polycarbonate resin and alkenylaromatic resin |
DE1139503B (de) * | 1959-11-28 | 1962-11-15 | N. V. Nederlandsche Combinatie voor Chemische Industrie, Amsterdam (Niederlande) | Verfahren zur Herstellung neuer substituierter 2,6-Diketopiperazine. |
NL273691A (es) * | 1961-01-19 | 1900-01-01 | ||
DE1189553B (de) * | 1962-08-09 | 1965-03-25 | Degussa | Verfahren zur Herstellung von racemischen und optisch aktiven Piperazinderivaten |
US3171837A (en) * | 1963-01-07 | 1965-03-02 | American Home Prod | 4-aroylalkyl-2-keto-and 2, 6-diketopiperazines |
US3969316A (en) * | 1973-07-12 | 1976-07-13 | Ciba-Geigy Corporation | 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby |
DE2362539C2 (de) * | 1973-12-17 | 1986-05-07 | Merck Patent Gmbh, 6100 Darmstadt | 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE2441261A1 (de) * | 1974-08-28 | 1976-03-18 | Merck Patent Gmbh | Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung |
DE2457971A1 (de) * | 1974-12-07 | 1976-06-10 | Merck Patent Gmbh | Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten |
DE2504250A1 (de) * | 1975-02-01 | 1976-08-05 | Merck Patent Gmbh | Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung |
-
1982
- 1982-01-29 FR FR8201758A patent/FR2520740A1/fr active Granted
- 1982-12-15 ES ES518241A patent/ES8400416A1/es not_active Expired
- 1982-12-22 IL IL67547A patent/IL67547A/xx unknown
-
1983
- 1983-01-07 EP EP83400044A patent/EP0086678B1/fr not_active Expired
- 1983-01-07 AT AT83400044T patent/ATE14126T1/de not_active IP Right Cessation
- 1983-01-07 DE DE8383400044T patent/DE3360328D1/de not_active Expired
- 1983-01-10 NZ NZ202981A patent/NZ202981A/en unknown
- 1983-01-11 ZA ZA83166A patent/ZA83166B/xx unknown
- 1983-01-11 FI FI830096A patent/FI75346C/fi not_active IP Right Cessation
- 1983-01-14 OA OA57895A patent/OA07301A/xx unknown
- 1983-01-20 KR KR1019830000205A patent/KR840003252A/ko not_active IP Right Cessation
- 1983-01-24 CA CA000420124A patent/CA1202629A/en not_active Expired
- 1983-01-26 CS CS83511A patent/CS235304B2/cs unknown
- 1983-01-26 DK DK30183A patent/DK30183A/da not_active Application Discontinuation
- 1983-01-28 JP JP58013634A patent/JPS58134091A/ja active Pending
- 1983-01-28 HU HU83292A patent/HU187848B/hu not_active IP Right Cessation
- 1983-01-31 US US06/462,397 patent/US4523013A/en not_active Expired - Fee Related
-
1985
- 1985-08-24 SG SG623/85A patent/SG62385G/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA83166B (en) | 1983-10-26 |
DK30183A (da) | 1983-07-30 |
OA07301A (fr) | 1984-08-31 |
EP0086678A1 (fr) | 1983-08-24 |
KR840003252A (ko) | 1984-08-20 |
EP0086678B1 (fr) | 1985-07-03 |
CA1202629A (en) | 1986-04-01 |
US4523013A (en) | 1985-06-11 |
IL67547A0 (en) | 1983-05-15 |
NZ202981A (en) | 1985-07-12 |
DK30183D0 (da) | 1983-01-26 |
FI830096A0 (fi) | 1983-01-11 |
ES518241A0 (es) | 1983-10-16 |
DE3360328D1 (en) | 1985-08-08 |
FI830096L (fi) | 1983-07-30 |
HU187848B (en) | 1986-02-28 |
FI75346B (fi) | 1988-02-29 |
CS235304B2 (en) | 1985-05-15 |
ATE14126T1 (de) | 1985-07-15 |
IL67547A (en) | 1985-07-31 |
JPS58134091A (ja) | 1983-08-10 |
FR2520740A1 (fr) | 1983-08-05 |
FI75346C (fi) | 1988-06-09 |
ES8400416A1 (es) | 1983-10-16 |
FR2520740B1 (es) | 1984-03-09 |
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