ZA83166B - Preparation of pyrazino-isoquinoline derivatives and intermediates therefor - Google Patents

Preparation of pyrazino-isoquinoline derivatives and intermediates therefor

Info

Publication number
ZA83166B
ZA83166B ZA83166A ZA83166A ZA83166B ZA 83166 B ZA83166 B ZA 83166B ZA 83166 A ZA83166 A ZA 83166A ZA 83166 A ZA83166 A ZA 83166A ZA 83166 B ZA83166 B ZA 83166B
Authority
ZA
South Africa
Prior art keywords
pyrazino
preparation
isoquinoline derivatives
intermediates therefor
acyl
Prior art date
Application number
ZA83166A
Other languages
English (en)
Inventor
Daniel Frehel
Jean-Pierre Maffrand
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of ZA83166B publication Critical patent/ZA83166B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
    • C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cosmetics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA83166A 1982-01-29 1983-01-11 Preparation of pyrazino-isoquinoline derivatives and intermediates therefor ZA83166B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8201758A FR2520740A1 (fr) 1982-01-29 1982-01-29 Procede pour la preparation d'acyl-2-hexahydro-1,3,4,6,7,11b-2h-pyrazino (2,1-a) isoquinoleinones-4 et intermediaires

Publications (1)

Publication Number Publication Date
ZA83166B true ZA83166B (en) 1983-10-26

Family

ID=9270646

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA83166A ZA83166B (en) 1982-01-29 1983-01-11 Preparation of pyrazino-isoquinoline derivatives and intermediates therefor

Country Status (18)

Country Link
US (1) US4523013A (xx)
EP (1) EP0086678B1 (xx)
JP (1) JPS58134091A (xx)
KR (1) KR840003252A (xx)
AT (1) ATE14126T1 (xx)
CA (1) CA1202629A (xx)
CS (1) CS235304B2 (xx)
DE (1) DE3360328D1 (xx)
DK (1) DK30183A (xx)
ES (1) ES518241A0 (xx)
FI (1) FI75346C (xx)
FR (1) FR2520740A1 (xx)
HU (1) HU187848B (xx)
IL (1) IL67547A (xx)
NZ (1) NZ202981A (xx)
OA (1) OA07301A (xx)
SG (1) SG62385G (xx)
ZA (1) ZA83166B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3472678D1 (de) * 1983-07-18 1988-08-18 Beecham Group Plc Benzazepine and benzoxazepine derivatives
GB8509435D0 (en) * 1985-04-12 1985-05-15 Beecham Group Plc Intermediates & process
HU208311B (en) * 1989-11-02 1993-09-28 Alkaloida Vegyeszeti Gyar Resolving process for producing enantiomers of 2-/4-(5-trifluoromethyl-2-pyridyloxy)-phenoxy/-propanoic acid
CN100503582C (zh) * 2005-03-01 2009-06-24 江苏工业学院 吡喹酮合成工艺
WO2012081036A2 (en) * 2010-12-13 2012-06-21 Sequent Scientific Limited A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione)
CN102786519B (zh) * 2011-05-17 2017-04-19 中国医学科学院药物研究所 吡喹酮晶b型物质及制备方法与在药品和保健品中应用
CN102786520A (zh) * 2011-05-17 2012-11-21 中国医学科学院药物研究所 吡喹酮晶a型物质及制备方法与在药品和保健品中应用
WO2013060292A1 (zh) * 2011-10-26 2013-05-02 苏州同力生物医药有限公司 制备左旋吡喹酮的方法
CN115466261A (zh) * 2022-09-15 2022-12-13 诚弘制药(威海)有限责任公司 一种吡喹酮的新制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE624686A (xx) *
US3239582A (en) * 1958-05-21 1966-03-08 Dow Chemical Co Blend of polycarbonate resin and alkenylaromatic resin
DE1139503B (de) * 1959-11-28 1962-11-15 N. V. Nederlandsche Combinatie voor Chemische Industrie, Amsterdam (Niederlande) Verfahren zur Herstellung neuer substituierter 2,6-Diketopiperazine.
NL273691A (xx) * 1961-01-19 1900-01-01
DE1189553B (de) * 1962-08-09 1965-03-25 Degussa Verfahren zur Herstellung von racemischen und optisch aktiven Piperazinderivaten
US3171837A (en) * 1963-01-07 1965-03-02 American Home Prod 4-aroylalkyl-2-keto-and 2, 6-diketopiperazines
US3969316A (en) * 1973-07-12 1976-07-13 Ciba-Geigy Corporation 3,5-Dialkyl-4-hydroxyphenylalkyl substituted piperazine diones and polymeric compositions stabilized thereby
DE2362539C2 (de) * 1973-12-17 1986-05-07 Merck Patent Gmbh, 6100 Darmstadt 2-Acyl-4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isochinoline, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2441261A1 (de) * 1974-08-28 1976-03-18 Merck Patent Gmbh Ringsubstituierte pyrazino-isochinolin-derivat und verfahren zu ihrer herstellung
DE2457971A1 (de) * 1974-12-07 1976-06-10 Merck Patent Gmbh Verfahren zur herstellung von 2-acyl4-oxo-pyrazino-isochinolin-derivaten
DE2504250A1 (de) * 1975-02-01 1976-08-05 Merck Patent Gmbh Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
DK30183D0 (da) 1983-01-26
HU187848B (en) 1986-02-28
IL67547A (en) 1985-07-31
ES8400416A1 (es) 1983-10-16
CA1202629A (en) 1986-04-01
CS235304B2 (en) 1985-05-15
DE3360328D1 (en) 1985-08-08
FI830096L (fi) 1983-07-30
KR840003252A (ko) 1984-08-20
EP0086678B1 (fr) 1985-07-03
US4523013A (en) 1985-06-11
FI75346C (fi) 1988-06-09
JPS58134091A (ja) 1983-08-10
FI830096A0 (fi) 1983-01-11
NZ202981A (en) 1985-07-12
DK30183A (da) 1983-07-30
ES518241A0 (es) 1983-10-16
FI75346B (fi) 1988-02-29
FR2520740B1 (xx) 1984-03-09
EP0086678A1 (fr) 1983-08-24
FR2520740A1 (fr) 1983-08-05
IL67547A0 (en) 1983-05-15
OA07301A (fr) 1984-08-31
ATE14126T1 (de) 1985-07-15
SG62385G (en) 1986-11-21

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