ES8303412A1 - Procedimiento de obtencion de nuevas xantinas con actividad farmacologica - Google Patents
Procedimiento de obtencion de nuevas xantinas con actividad farmacologicaInfo
- Publication number
- ES8303412A1 ES8303412A1 ES506046A ES506046A ES8303412A1 ES 8303412 A1 ES8303412 A1 ES 8303412A1 ES 506046 A ES506046 A ES 506046A ES 506046 A ES506046 A ES 506046A ES 8303412 A1 ES8303412 A1 ES 8303412A1
- Authority
- ES
- Spain
- Prior art keywords
- xanthines
- antiallergenic
- antiasthmatic
- halogen
- salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 1
- 229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 title 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 abstract 1
- 230000001088 anti-asthma Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000000924 antiasthmatic agent Substances 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE XANTINAS Y DE SUS SALES DE ADICION DE ACIDO FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R ES HIDROGENO O HALOGENO. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA PIPERAZINA DE FORMULA (III), EN LAS QUE X ES HALOGENO, Y R ES HIDROGENO O HALOGENO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, EN PRESENCIA DE UN CATALIZADOR BASICO, A TEMPERATURAS COMPRENDIDAS ENTRE LA AMBIENTE Y LA DE EBULLICION DE LA MEZCLA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIALERGICA, ANTIASMATICA Y ANTIHISTAMINICA.
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES506046A ES8303412A1 (es) | 1981-10-06 | 1981-10-06 | Procedimiento de obtencion de nuevas xantinas con actividad farmacologica |
| FR8216580A FR2514003A1 (fr) | 1981-10-06 | 1982-09-30 | Nouvelles xanthines a activite pharmacologique, leur procede d'obtention, les compositions pharmaceutiques qui les contiennent et leur utilisation en medecine humaine |
| IT68159/82A IT1191214B (it) | 1981-10-06 | 1982-10-01 | Xantine con attivita' farmacologica processo di ottenimento di esse e composizioni farmaceutiche che le contengono |
| JP57173129A JPS5872584A (ja) | 1981-10-06 | 1982-10-01 | 新規キサンチン誘導体、その製法ならびに抗アレルギ−剤 |
| BE2/59858A BE894597A (fr) | 1981-10-06 | 1982-10-05 | Nouvelles xanthines a activite pharmacologique, leur procede d'obtention, les compositions pharmaceutiques les contenant et leur utilisation en medecine humaine |
| GB08228432A GB2107709A (en) | 1981-10-06 | 1982-10-05 | Xanthines |
| DE19823237064 DE3237064A1 (de) | 1981-10-06 | 1982-10-06 | Pharmakologisch aktive xanthine, verfahren zu ihrer gewinnung und pharmazeutische zubereitungen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES506046A ES8303412A1 (es) | 1981-10-06 | 1981-10-06 | Procedimiento de obtencion de nuevas xantinas con actividad farmacologica |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES506046A0 ES506046A0 (es) | 1983-02-01 |
| ES8303412A1 true ES8303412A1 (es) | 1983-02-01 |
Family
ID=8483044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506046A Expired ES8303412A1 (es) | 1981-10-06 | 1981-10-06 | Procedimiento de obtencion de nuevas xantinas con actividad farmacologica |
Country Status (7)
| Country | Link |
|---|---|
| JP (1) | JPS5872584A (es) |
| BE (1) | BE894597A (es) |
| DE (1) | DE3237064A1 (es) |
| ES (1) | ES8303412A1 (es) |
| FR (1) | FR2514003A1 (es) |
| GB (1) | GB2107709A (es) |
| IT (1) | IT1191214B (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2531085A1 (fr) * | 1982-07-28 | 1984-02-03 | Adir | Nouveaux derives de la xanthine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
| US4710572A (en) * | 1986-07-30 | 1987-12-01 | American Home Products Corporation | Histamine H1 antagonists |
| US5484920A (en) * | 1992-04-08 | 1996-01-16 | Kyowa Hakko Kogyo Co., Ltd. | Therapeutic agent for Parkinson's disease |
| JP2613355B2 (ja) * | 1992-09-28 | 1997-05-28 | 協和醗酵工業株式会社 | パーキンソン氏病治療剤 |
| GB0009479D0 (en) * | 2000-04-17 | 2000-06-07 | Cipla Limited | Antihistaminic compounds |
| TWI268930B (en) * | 2000-07-28 | 2006-12-21 | Ing-Jun Chen | Theophylline and 3-isobutyl-1-methylxanthine based N-7 substituted derivatives and pharmaceutical composition thereof |
| EA017351B1 (ru) * | 2007-03-29 | 2012-11-30 | Общество С Ограниченной Ответственностью "Фармвинг" | Средство противогистаминного антиаллергического действия и способ его получения |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1133989A (en) * | 1964-12-08 | 1968-11-20 | Chugai Pharmaceutical Co Ltd | Theophylline derivatives, their salts and process for preparing the same |
| US4426383A (en) * | 1980-09-04 | 1984-01-17 | Eisai Co., Ltd. | Theophylline and theobromine derivatives |
| EP0087810B1 (en) * | 1982-03-02 | 1986-06-25 | Eisai Co., Ltd. | Antiphlogistic/antipyretic/analgesic pharmaceutical compositions containing theophylline derivatives as active ingredient |
-
1981
- 1981-10-06 ES ES506046A patent/ES8303412A1/es not_active Expired
-
1982
- 1982-09-30 FR FR8216580A patent/FR2514003A1/fr not_active Withdrawn
- 1982-10-01 IT IT68159/82A patent/IT1191214B/it active
- 1982-10-01 JP JP57173129A patent/JPS5872584A/ja active Pending
- 1982-10-05 GB GB08228432A patent/GB2107709A/en not_active Withdrawn
- 1982-10-05 BE BE2/59858A patent/BE894597A/fr not_active IP Right Cessation
- 1982-10-06 DE DE19823237064 patent/DE3237064A1/de not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| GB2107709A (en) | 1983-05-05 |
| JPS5872584A (ja) | 1983-04-30 |
| ES506046A0 (es) | 1983-02-01 |
| FR2514003A1 (fr) | 1983-04-08 |
| IT1191214B (it) | 1988-02-24 |
| DE3237064A1 (de) | 1983-04-21 |
| IT8268159A0 (it) | 1982-10-01 |
| BE894597A (fr) | 1983-01-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES509449A0 (es) | "un procedimiento de preparacion de derivados de 1,3-dihidro-6-metil-7-hidroxi-furo-3,4-c-piridina". | |
| AU1699383A (en) | 2-azabicyclo(2.2.2.)octane-3-carboxylic acid derivatives | |
| GB2130580B (en) | Derivatives of 4-oxo-1, 4-dihydronicotinic acid | |
| EP0174464A3 (en) | Substituted benzyl phthalazinone derivatives | |
| ES8607271A1 (es) | Amidinohidrazonas | |
| ES514340A0 (es) | "procedimiento de obtencion de nuevos derivados de piperazina". | |
| EP0107735A4 (en) | NEW PYRIDAZINONE DERIVATIVES. | |
| ES8303412A1 (es) | Procedimiento de obtencion de nuevas xantinas con actividad farmacologica | |
| RO83114A (ro) | Procedeu pentru prepararea ditiazolil-(2,2')-disulfurilor | |
| ES8304548A1 (es) | "procedimiento de preparacion de derivados de fenetanolamina". | |
| AU9141182A (en) | 9-(3-(3,5-cis-dimethylpiperazino)propyl)carbazole for treatment of anxiety | |
| ES462755A1 (es) | Procedimiento para la preparacion de esteres bencilicos del acido 2-isopropil-4-fenil-3-butenico. | |
| AU8036682A (en) | Substituted aliphatic secondary amines | |
| ES512230A0 (es) | "procedimiento de preparacion de derivados (7e,9z)-alcadienoles". | |
| EP0118564A4 (en) | 4-AMINO-TETRAHYDRO-2-NAPHTOIC ACID DERIVATIVES. | |
| NO872521L (no) | Fremgangsmaate for overfoering av data. | |
| ES511405A0 (es) | "procedimiento de preparar compuestos 1(2h)-isoquinolonicos y similares". | |
| AU553493B2 (en) | 3,7alpha-diazacyclohepta(j,k)fluoriene derivatives | |
| DE3261303D1 (en) | Process for the preparation of 4,4'-dibenzoylamino dianthrimide carbazole | |
| AR227703A1 (es) | Procedimiento para preparar 1-substituido-6-n-propil-8-metilimidazo(1,5-d)as-triazin-4(3h)-onas | |
| JPS5293771A (en) | Benzotriazoles | |
| EP0162079A4 (en) | USE OF ARG-PHE-AMIDE DERIVATIVES. | |
| JPS5285178A (en) | Di(tri-lower-alkylstannyl)pyrimidine derivatives | |
| FI77023B (fi) | Foerfarande foer framstaellning av 1-alkyl- eller 1,4-dialkyl-1h-pyrrol-2-aettiksyraestrar. | |
| JPS5283520A (en) | Novel 2-arylthio-cyclopentanones |