SG47948A1 - Compounds for the treatment of neurodegenerative disorders - Google Patents

Compounds for the treatment of neurodegenerative disorders

Info

Publication number
SG47948A1
SG47948A1 SG1996005610A SG1996005610A SG47948A1 SG 47948 A1 SG47948 A1 SG 47948A1 SG 1996005610 A SG1996005610 A SG 1996005610A SG 1996005610 A SG1996005610 A SG 1996005610A SG 47948 A1 SG47948 A1 SG 47948A1
Authority
SG
Singapore
Prior art keywords
treatment
neurodegenerative disorders
compounds
pyridineethanamine
alpha
Prior art date
Application number
SG1996005610A
Other languages
English (en)
Inventor
Michael Balestra
Ronald Conrad Griffith
Robert John Murray
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929207339A external-priority patent/GB9207339D0/en
Priority claimed from GB929208290A external-priority patent/GB9208290D0/en
Application filed by Astra Ab filed Critical Astra Ab
Publication of SG47948A1 publication Critical patent/SG47948A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • A61P25/10Antiepileptics; Anticonvulsants for petit-mal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • A61P25/12Antiepileptics; Anticonvulsants for grand-mal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
SG1996005610A 1992-04-03 1993-04-01 Compounds for the treatment of neurodegenerative disorders SG47948A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929207339A GB9207339D0 (en) 1992-04-03 1992-04-03 Pharmaceutical compound
GB929208290A GB9208290D0 (en) 1992-04-15 1992-04-15 Pharmaceutical compound having neuroprotective properties

Publications (1)

Publication Number Publication Date
SG47948A1 true SG47948A1 (en) 1998-04-17

Family

ID=26300643

Family Applications (1)

Application Number Title Priority Date Filing Date
SG1996005610A SG47948A1 (en) 1992-04-03 1993-04-01 Compounds for the treatment of neurodegenerative disorders

Country Status (28)

Country Link
EP (1) EP0633879B1 (enExample)
JP (2) JP3120810B2 (enExample)
KR (1) KR100259567B1 (enExample)
CN (1) CN1044367C (enExample)
AT (1) ATE163925T1 (enExample)
AU (2) AU3897693A (enExample)
CA (1) CA2133427C (enExample)
CZ (1) CZ288519B6 (enExample)
DE (1) DE69317411T2 (enExample)
DK (1) DK0633879T3 (enExample)
DZ (1) DZ1677A1 (enExample)
ES (1) ES2115055T3 (enExample)
FI (1) FI105025B (enExample)
HU (1) HU211529A9 (enExample)
IL (1) IL105276A (enExample)
MA (1) MA22866A1 (enExample)
MX (1) MX9301935A (enExample)
MY (1) MY110149A (enExample)
NO (1) NO302170B1 (enExample)
NZ (1) NZ251384A (enExample)
PL (1) PL180014B1 (enExample)
RU (1) RU2128650C1 (enExample)
SG (1) SG47948A1 (enExample)
SK (1) SK281258B6 (enExample)
TW (1) TW282455B (enExample)
UA (1) UA29437C2 (enExample)
WO (1) WO1993020052A1 (enExample)
ZA (1) ZA932415B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9320273D0 (en) 1993-04-01 1993-11-17 Fisons Corp Compound useful in therapy
ES2083972T3 (es) * 1988-08-12 1996-05-01 Astra Ab Arilalquil-aminas y -amidas con propiedades anticonvulsivas y neuroprotectoras.
ZA942140B (en) 1993-04-01 1994-10-03 Fisons Corp Salt of (S)-alpha-phenyl-2-pyridineethanamine useful in therapy
SE9901077D0 (sv) * 1999-03-23 1999-03-23 Astra Ab Novel use
SE9901237D0 (sv) * 1999-04-06 1999-04-06 Astra Ab Novel use
SE9901340D0 (sv) 1999-04-15 1999-04-15 Astra Pharma Prod Novel process
EP1202986B1 (en) * 1999-07-28 2005-10-12 Ortho-McNeil Pharmaceutical, Inc. Amine and amide derivatives as ligands for the neuropeptide y y5 receptor useful in the treatment of obesity and other disorders
WO2007017652A2 (en) * 2005-08-10 2007-02-15 Astrazeneca Ab Arylakylamines for the treatment of cancer
US8013165B2 (en) * 2008-12-24 2011-09-06 Astrazeneca Ab Ethanamine compounds and methods of using the same 545
CN104114714A (zh) * 2011-12-14 2014-10-22 阿斯利康(瑞典)有限公司 Gabr-a2诊断
KR102336426B1 (ko) 2013-11-05 2021-12-08 아스트라제네카 아베 Nmda 길항제 전구약물
BR112022025900A2 (pt) * 2020-06-23 2023-01-10 Biohaven Therapeutics Ltd Formulações tópicas de (1s)-1-fenil-2-piridin-2-iletanamina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0320006A3 (en) * 1987-12-11 1990-12-19 Laboratoires Syntex Uses of 1,4-dihydropyridines
ES2083972T3 (es) * 1988-08-12 1996-05-01 Astra Ab Arilalquil-aminas y -amidas con propiedades anticonvulsivas y neuroprotectoras.

Also Published As

Publication number Publication date
HK1009331A1 (en) 1999-05-28
FI944546A0 (fi) 1994-09-30
IL105276A0 (en) 1993-08-18
CA2133427A1 (en) 1993-10-14
SK281258B6 (sk) 2001-01-18
FI105025B (fi) 2000-05-31
IL105276A (en) 1997-06-10
WO1993020052A1 (en) 1993-10-14
EP0633879A1 (en) 1995-01-18
CA2133427C (en) 2003-06-10
ATE163925T1 (de) 1998-03-15
DK0633879T3 (da) 1998-09-28
MX9301935A (es) 1994-08-31
AU705419B2 (en) 1999-05-20
EP0633879B1 (en) 1998-03-11
DE69317411D1 (de) 1998-04-16
NO302170B1 (no) 1998-02-02
JP2000319259A (ja) 2000-11-21
PL180014B1 (pl) 2000-11-30
MY110149A (en) 1998-02-28
CZ240994A3 (en) 1995-12-13
RU94042465A (ru) 1996-07-20
ES2115055T3 (es) 1998-06-16
HU211529A9 (en) 1995-11-28
NO943645D0 (no) 1994-09-30
DE69317411T2 (de) 1998-07-30
KR100259567B1 (ko) 2000-07-01
AU7545696A (en) 1997-02-13
UA29437C2 (uk) 2000-11-15
MA22866A1 (fr) 1993-12-31
CN1044367C (zh) 1999-07-28
JP3120810B2 (ja) 2000-12-25
CZ288519B6 (cs) 2001-07-11
ZA932415B (en) 1993-10-22
RU2128650C1 (ru) 1999-04-10
TW282455B (enExample) 1996-08-01
JPH07505385A (ja) 1995-06-15
FI944546L (fi) 1994-09-30
NZ251384A (en) 1996-10-28
AU3897693A (en) 1993-11-08
NO943645L (no) 1994-11-16
DZ1677A1 (fr) 2002-02-17
CN1081669A (zh) 1994-02-09
SK117794A3 (en) 1995-05-10

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