SG32390G - Novel 8a-acylaminoergolines - Google Patents

Novel 8a-acylaminoergolines

Info

Publication number
SG32390G
SG32390G SG32390A SG32390A SG32390G SG 32390 G SG32390 G SG 32390G SG 32390 A SG32390 A SG 32390A SG 32390 A SG32390 A SG 32390A SG 32390 G SG32390 G SG 32390G
Authority
SG
Singapore
Prior art keywords
acylaminoergolines
novel
Prior art date
Application number
SG32390A
Other languages
English (en)
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of SG32390G publication Critical patent/SG32390G/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06—Lysergic acid amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG32390A 1984-01-12 1990-05-02 Novel 8a-acylaminoergolines SG32390G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3400853 1984-01-12

Publications (1)

Publication Number Publication Date
SG32390G true SG32390G (en) 1990-08-03

Family

ID=6224786

Family Applications (1)

Application Number Title Priority Date Filing Date
SG32390A SG32390G (en) 1984-01-12 1990-05-02 Novel 8a-acylaminoergolines

Country Status (28)

Country Link
US (2) US4950672A (sv)
JP (1) JPH0655739B2 (sv)
AT (1) AT391317B (sv)
AU (3) AU583489B2 (sv)
BE (1) BE901456A (sv)
CA (1) CA1245640A (sv)
CH (1) CH664568A5 (sv)
CY (1) CY1542A (sv)
DE (1) DE3500251C2 (sv)
DK (1) DK169891B1 (sv)
ES (1) ES8605514A1 (sv)
FI (1) FI82466C (sv)
FR (1) FR2560196B1 (sv)
GB (1) GB2152507B (sv)
GR (1) GR850065B (sv)
HK (1) HK48590A (sv)
HU (1) HU197569B (sv)
IE (1) IE58228B1 (sv)
IL (1) IL74043A (sv)
IT (1) IT1214648B (sv)
LU (1) LU85725A1 (sv)
NL (1) NL193541C (sv)
NZ (1) NZ210818A (sv)
PH (1) PH23286A (sv)
PT (1) PT79818B (sv)
SE (1) SE460420B (sv)
SG (1) SG32390G (sv)
ZA (1) ZA85276B (sv)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
EP0160842B1 (de) * 1984-04-09 1994-06-22 Schering Aktiengesellschaft 2-substituierte Ergolin-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
NL8700046A (nl) * 1986-01-24 1987-08-17 Sandoz Ag 8 alfa-acylaminoergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
US4981859A (en) * 1987-06-15 1991-01-01 Cycloalkylamides of (8 beta )-1-alkyl-6-(substituted)ergolines
US4931447A (en) * 1987-06-15 1990-06-05 Eli Lilly And Company Cycloalkylamides of (8β)-1-alkyl-6-(substituted) ergolines
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto
DE3820159A1 (de) * 1987-06-23 1989-01-05 Sandoz Ag 8(alpha)-acylaminoergolin, seine herstellung und dieses enthaltende arzneimittel
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
GB8824744D0 (en) * 1988-10-21 1988-11-30 Erba Carlo Spa Antiemesis ergoline derivatives
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
CN107428745A (zh) 2015-01-20 2017-12-01 Xoc制药股份有限公司 麦角灵化合物及其用途
US9676776B2 (en) * 2015-01-20 2017-06-13 Xoc Pharmaceuticals, Inc. Isoergoline compounds and uses thereof
AU2018275873A1 (en) 2017-06-01 2019-12-19 Xoc Pharmaceuticals, Inc. Ergoline derivatives for use in medicine

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
US2864822A (en) * 1956-10-22 1958-12-16 Lilly Co Eli 9-amino-7-methyl-belta10-ergolene and derivatives thereof
CH622519A5 (en) * 1974-07-05 1981-04-15 Hoechst Ag Process for the preparation of hydroxyalkylxanthines
US4348392A (en) * 1974-07-19 1982-09-07 Sandoz Ltd. 8α-Substituted ergoline-I derivatives
GB1517973A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 6-methyl-8alpha-n,n-dimethylsulphamoylaminoergoline i
US3922347A (en) * 1974-12-19 1975-11-25 Lilly Co Eli Method of inhibiting prolactin secretion with 8-acylaminoergolenes
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
CH622518A5 (en) * 1976-12-14 1981-04-15 Sandoz Ag Process for the preparation of novel ergoline compounds
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
NL193541C (nl) * 1984-01-12 2000-01-04 Novartis Ag 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
NL8503426A (nl) * 1984-12-24 1986-07-16 Sandoz Ag 8alfa-acylamino-ergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto

Also Published As

Publication number Publication date
GB8500454D0 (en) 1985-02-13
DK12685D0 (da) 1985-01-10
IT1214648B (it) 1990-01-18
GB2152507B (en) 1987-07-15
US5077298A (en) 1991-12-31
CY1542A (en) 1991-03-22
PT79818A (en) 1985-02-01
AU2506688A (en) 1989-02-23
NZ210818A (en) 1989-02-24
ZA85276B (en) 1986-08-27
US4950672A (en) 1990-08-21
HUT37148A (en) 1985-11-28
NL8500008A (nl) 1985-08-01
DE3500251A1 (de) 1985-07-18
DE3500251C2 (de) 1995-01-26
BE901456A (fr) 1985-07-08
DK12685A (da) 1985-07-13
SE460420B (sv) 1989-10-09
AU583489B2 (en) 1989-05-04
DK169891B1 (da) 1995-03-27
IL74043A (en) 1988-10-31
ES539511A0 (es) 1986-03-16
IL74043A0 (en) 1985-04-30
FI850130L (fi) 1985-07-13
PH23286A (en) 1989-06-30
JPS60174783A (ja) 1985-09-09
AU2506788A (en) 1989-03-02
AU609539B2 (en) 1991-05-02
HK48590A (en) 1990-06-29
CA1245640A (en) 1988-11-29
FR2560196B1 (fr) 1986-07-18
AU618290B2 (en) 1991-12-19
FI82466B (fi) 1990-11-30
AT391317B (de) 1990-09-25
FI82466C (sv) 1991-03-11
ATA5985A (de) 1990-03-15
PT79818B (en) 1987-01-07
JPH0655739B2 (ja) 1994-07-27
AU3760985A (en) 1985-07-18
CH664568A5 (de) 1988-03-15
NL193541B (nl) 1999-09-01
FR2560196A1 (fr) 1985-08-30
GB2152507A (en) 1985-08-07
FI850130A0 (fi) 1985-01-11
IT8547538A0 (it) 1985-01-11
NL193541C (nl) 2000-01-04
IE850064L (en) 1985-07-12
SE8500107D0 (sv) 1985-01-10
SE8500107L (sv) 1985-07-13
HU197569B (en) 1989-04-28
LU85725A1 (fr) 1985-10-22
ES8605514A1 (es) 1986-03-16
IE58228B1 (en) 1993-08-11
GR850065B (sv) 1985-05-03

Similar Documents

Publication Publication Date Title
AR242476A1 (es) Una maquina cosechadora.
ZA857871B (en) Alkylsulfonamidophenylalkylamines
ZA855092B (en) Novel isoindolinyl-alkyl-piperazines
PH23286A (en) Novel 80-acylaminoergolines
EP0191269A3 (en) Novel homopropargylamines
ZA852440B (en) Novel substituted-aminohydroxypropoxy-thiadiazoles
ZA858971B (en) Novel homopropargylamines
BG45796A1 (en) Vibro- rammer
BG47593A1 (en) Hydroimpulser
BG38439A1 (en) Hydrotransmission
CS1009284A1 (en) Zesilovac jasu neutronoveho obrazu
CS1007084A1 (en) Sklicidlo
CS1006984A1 (en) Sklicidlo
CS1006884A1 (en) Unaseci zarizeni
AU89905S (en) Flounce
CS1006184A1 (en) Skrabaky behounu vibracniho valce
AU91063S (en) Nameboard
AU91199S (en) Tea-towel
CS100484A1 (en) Zpusob botnani polymernich castic
BG47596A1 (en) Hydroimpulser
BG37574A1 (en) Roll- pallet
BG47435A1 (en) Hydroimpulser
BG38428A1 (en) Vibro- roller
CS1010084A1 (en) Polohovaci pripravok
BG39244A1 (en) Hydrotransmission