SG32390G - Novel 8a-acylaminoergolines - Google Patents

Novel 8a-acylaminoergolines

Info

Publication number
SG32390G
SG32390G SG32390A SG32390A SG32390G SG 32390 G SG32390 G SG 32390G SG 32390 A SG32390 A SG 32390A SG 32390 A SG32390 A SG 32390A SG 32390 G SG32390 G SG 32390G
Authority
SG
Singapore
Prior art keywords
acylaminoergolines
novel
Prior art date
Application number
SG32390A
Other languages
English (en)
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of SG32390G publication Critical patent/SG32390G/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C07D457/06Lysergic acid amides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12Nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SG32390A 1984-01-12 1990-05-02 Novel 8a-acylaminoergolines SG32390G (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3400853 1984-01-12

Publications (1)

Publication Number Publication Date
SG32390G true SG32390G (en) 1990-08-03

Family

ID=6224786

Family Applications (1)

Application Number Title Priority Date Filing Date
SG32390A SG32390G (en) 1984-01-12 1990-05-02 Novel 8a-acylaminoergolines

Country Status (28)

Country Link
US (2) US4950672A (forum.php)
JP (1) JPH0655739B2 (forum.php)
AT (1) AT391317B (forum.php)
AU (3) AU583489B2 (forum.php)
BE (1) BE901456A (forum.php)
CA (1) CA1245640A (forum.php)
CH (1) CH664568A5 (forum.php)
CY (1) CY1542A (forum.php)
DE (1) DE3500251C2 (forum.php)
DK (1) DK169891B1 (forum.php)
ES (1) ES8605514A1 (forum.php)
FI (1) FI82466C (forum.php)
FR (1) FR2560196B1 (forum.php)
GB (1) GB2152507B (forum.php)
GR (1) GR850065B (forum.php)
HK (1) HK48590A (forum.php)
HU (1) HU197569B (forum.php)
IE (1) IE58228B1 (forum.php)
IL (1) IL74043A (forum.php)
IT (1) IT1214648B (forum.php)
LU (1) LU85725A1 (forum.php)
NL (1) NL193541C (forum.php)
NZ (1) NZ210818A (forum.php)
PH (1) PH23286A (forum.php)
PT (1) PT79818B (forum.php)
SE (1) SE460420B (forum.php)
SG (1) SG32390G (forum.php)
ZA (1) ZA85276B (forum.php)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU197569B (en) * 1984-01-12 1989-04-28 Sandoz Ag Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
NL8700046A (nl) * 1986-01-24 1987-08-17 Sandoz Ag 8 alfa-acylaminoergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
US4931447A (en) * 1987-06-15 1990-06-05 Eli Lilly And Company Cycloalkylamides of (8β)-1-alkyl-6-(substituted) ergolines
US4981859A (en) * 1987-06-15 1991-01-01 Cycloalkylamides of (8 beta )-1-alkyl-6-(substituted)ergolines
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto
DE3820159A1 (de) * 1987-06-23 1989-01-05 Sandoz Ag 8(alpha)-acylaminoergolin, seine herstellung und dieses enthaltende arzneimittel
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
GB8824744D0 (en) * 1988-10-21 1988-11-30 Erba Carlo Spa Antiemesis ergoline derivatives
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
JP2018502889A (ja) * 2015-01-20 2018-02-01 エックスオーシー ファーマシューティカルズ インコーポレイテッドXoc Pharmaceuticals, Inc イソエルゴリン化合物およびその使用
MX2017009405A (es) 2015-01-20 2018-01-18 Xoc Pharmaceuticals Inc Compuestos de tipo ergolina y usos de estos.
BR112019025420A2 (pt) 2017-06-01 2020-06-16 Xoc Pharmaceuticals, Inc. Compostos policíclicos e usos destes

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3218323A (en) * 1965-11-16 Esters of i,g-dimethyl-b-ergolenyl carbamic acid
US2864822A (en) * 1956-10-22 1958-12-16 Lilly Co Eli 9-amino-7-methyl-belta10-ergolene and derivatives thereof
CH622519A5 (en) * 1974-07-05 1981-04-15 Hoechst Ag Process for the preparation of hydroxyalkylxanthines
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
US4348392A (en) * 1974-07-19 1982-09-07 Sandoz Ltd. 8α-Substituted ergoline-I derivatives
US3922347A (en) * 1974-12-19 1975-11-25 Lilly Co Eli Method of inhibiting prolactin secretion with 8-acylaminoergolenes
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
DE2656344A1 (de) * 1975-12-23 1977-07-07 Sandoz Ag Ergolinderivate, ihre verwendung und herstellung
CH622518A5 (en) * 1976-12-14 1981-04-15 Sandoz Ag Process for the preparation of novel ergoline compounds
CH644606A5 (de) * 1980-09-23 1984-08-15 Sandoz Ag Verfahren zur isomerisierung von 9,10-dihydrolysergsaeurederivaten.
DE3151912A1 (de) * 1981-12-23 1983-06-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue ergolin-aminoderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel
HU197569B (en) * 1984-01-12 1989-04-28 Sandoz Ag Process for producing 8alpha-acylaminoergoline derivatives and pharmaceuticals comprising such compounds
NL8503426A (nl) * 1984-12-24 1986-07-16 Sandoz Ag 8alfa-acylamino-ergolinen, werkwijzen voor hun bereiding en farmaceutische preparaten die ze bevatten.
IT1219652B (it) * 1987-06-23 1990-05-24 Sandoz Ag 8-acilamminoergolina,la sua preparazione e il suo impiego come medicamneto

Also Published As

Publication number Publication date
JPH0655739B2 (ja) 1994-07-27
FR2560196B1 (fr) 1986-07-18
SE8500107D0 (sv) 1985-01-10
SE8500107L (sv) 1985-07-13
CY1542A (en) 1991-03-22
AU618290B2 (en) 1991-12-19
GB8500454D0 (en) 1985-02-13
IE850064L (en) 1985-07-12
IT1214648B (it) 1990-01-18
PT79818B (en) 1987-01-07
BE901456A (fr) 1985-07-08
AU2506688A (en) 1989-02-23
IE58228B1 (en) 1993-08-11
FI850130L (fi) 1985-07-13
FI82466C (fi) 1991-03-11
JPS60174783A (ja) 1985-09-09
NL193541B (nl) 1999-09-01
NL8500008A (nl) 1985-08-01
CH664568A5 (de) 1988-03-15
FR2560196A1 (fr) 1985-08-30
PH23286A (en) 1989-06-30
AU3760985A (en) 1985-07-18
AU609539B2 (en) 1991-05-02
CA1245640A (en) 1988-11-29
ES8605514A1 (es) 1986-03-16
AU583489B2 (en) 1989-05-04
DK12685D0 (da) 1985-01-10
PT79818A (en) 1985-02-01
ATA5985A (de) 1990-03-15
IL74043A (en) 1988-10-31
DK12685A (da) 1985-07-13
GR850065B (forum.php) 1985-05-03
DE3500251A1 (de) 1985-07-18
AT391317B (de) 1990-09-25
LU85725A1 (fr) 1985-10-22
HUT37148A (en) 1985-11-28
HK48590A (en) 1990-06-29
SE460420B (sv) 1989-10-09
IT8547538A0 (it) 1985-01-11
GB2152507A (en) 1985-08-07
HU197569B (en) 1989-04-28
NL193541C (nl) 2000-01-04
US4950672A (en) 1990-08-21
GB2152507B (en) 1987-07-15
NZ210818A (en) 1989-02-24
DK169891B1 (da) 1995-03-27
IL74043A0 (en) 1985-04-30
DE3500251C2 (de) 1995-01-26
ES539511A0 (es) 1986-03-16
AU2506788A (en) 1989-03-02
FI850130A0 (fi) 1985-01-11
US5077298A (en) 1991-12-31
ZA85276B (en) 1986-08-27
FI82466B (fi) 1990-11-30

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