SG185285A1 - Benzamide mglur5 positive allosteric modulators and methods of making and using same - Google Patents

Benzamide mglur5 positive allosteric modulators and methods of making and using same Download PDF

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Publication number
SG185285A1
SG185285A1 SG2012074621A SG2012074621A SG185285A1 SG 185285 A1 SG185285 A1 SG 185285A1 SG 2012074621 A SG2012074621 A SG 2012074621A SG 2012074621 A SG2012074621 A SG 2012074621A SG 185285 A1 SG185285 A1 SG 185285A1
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Singapore
Prior art keywords
optionally substituted
hydrogen
carbon atoms
amino
compound
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SG2012074621A
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English (en)
Inventor
P Jeffrey Conn
Craig W Lindsley
Charles David Weaver
Alice L Rodriguez
Colleen M Niswender
Carrie K Jones
Richard Williams
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Univ Vanderbilt
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Publication of SG185285A1 publication Critical patent/SG185285A1/en

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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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SG2012074621A 2007-06-03 2008-06-03 Benzamide mglur5 positive allosteric modulators and methods of making and using same SG185285A1 (en)

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