SG182471A1 - 6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate - Google Patents

6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate Download PDF

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Publication number
SG182471A1
SG182471A1 SG2012051140A SG2012051140A SG182471A1 SG 182471 A1 SG182471 A1 SG 182471A1 SG 2012051140 A SG2012051140 A SG 2012051140A SG 2012051140 A SG2012051140 A SG 2012051140A SG 182471 A1 SG182471 A1 SG 182471A1
Authority
SG
Singapore
Prior art keywords
purin
dihydro
piperidinyl
amino
pentyl
Prior art date
Application number
SG2012051140A
Other languages
English (en)
Inventor
Robert Hermann Gibbon
Amanda Lucas
Stephen Andrew Hermitage
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of SG182471A1 publication Critical patent/SG182471A1/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • A61K31/522Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Saccharide Compounds (AREA)
SG2012051140A 2010-02-10 2011-02-08 6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate SG182471A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30301010P 2010-02-10 2010-02-10
PCT/EP2011/051830 WO2011098452A1 (en) 2010-02-10 2011-02-08 6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate

Publications (1)

Publication Number Publication Date
SG182471A1 true SG182471A1 (en) 2012-08-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012051140A SG182471A1 (en) 2010-02-10 2011-02-08 6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate

Country Status (23)

Country Link
US (1) US8703754B2 (enExample)
EP (1) EP2534149B1 (enExample)
JP (1) JP5922587B2 (enExample)
KR (1) KR101773541B1 (enExample)
CN (1) CN102753553B (enExample)
AU (1) AU2011214468B2 (enExample)
BR (1) BR112012018904A2 (enExample)
CA (1) CA2786973C (enExample)
DK (1) DK2534149T3 (enExample)
EA (1) EA021048B1 (enExample)
ES (1) ES2525826T3 (enExample)
HR (1) HRP20141258T1 (enExample)
IL (1) IL220845A (enExample)
ME (1) ME01926B (enExample)
MX (1) MX2012009316A (enExample)
PL (1) PL2534149T3 (enExample)
PT (1) PT2534149E (enExample)
RS (1) RS53745B1 (enExample)
SG (1) SG182471A1 (enExample)
SI (1) SI2534149T1 (enExample)
SM (1) SMT201400196B (enExample)
WO (1) WO2011098452A1 (enExample)
ZA (1) ZA201205995B (enExample)

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Also Published As

Publication number Publication date
MX2012009316A (es) 2012-09-12
KR20120135408A (ko) 2012-12-13
CA2786973C (en) 2018-04-10
BR112012018904A2 (pt) 2020-09-01
SMT201400196B (it) 2015-01-15
CA2786973A1 (en) 2011-08-18
AU2011214468A1 (en) 2012-08-09
JP2013519645A (ja) 2013-05-30
JP5922587B2 (ja) 2016-05-24
KR101773541B1 (ko) 2017-08-31
CN102753553B (zh) 2016-03-30
IL220845A (en) 2016-08-31
US20120308609A1 (en) 2012-12-06
HRP20141258T1 (hr) 2015-02-27
DK2534149T3 (da) 2015-01-05
PL2534149T3 (pl) 2015-03-31
ES2525826T3 (es) 2014-12-30
RS53745B1 (sr) 2015-06-30
EA021048B1 (ru) 2015-03-31
EP2534149A1 (en) 2012-12-19
PT2534149E (pt) 2014-12-23
SI2534149T1 (sl) 2015-02-27
CN102753553A (zh) 2012-10-24
ZA201205995B (en) 2014-01-29
EA201290631A1 (ru) 2013-03-29
WO2011098452A1 (en) 2011-08-18
AU2011214468B2 (en) 2015-05-28
EP2534149B1 (en) 2014-10-15
US8703754B2 (en) 2014-04-22
ME01926B (me) 2015-05-20

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