SG178411A1 - Thermal block assemblies and instruments providing low thermal non-uniformity for rapid thermal cycling - Google Patents

Thermal block assemblies and instruments providing low thermal non-uniformity for rapid thermal cycling Download PDF

Info

Publication number
SG178411A1
SG178411A1 SG2012010278A SG2012010278A SG178411A1 SG 178411 A1 SG178411 A1 SG 178411A1 SG 2012010278 A SG2012010278 A SG 2012010278A SG 2012010278 A SG2012010278 A SG 2012010278A SG 178411 A1 SG178411 A1 SG 178411A1
Authority
SG
Singapore
Prior art keywords
thermal
block assembly
block
assembly
sample
Prior art date
Application number
SG2012010278A
Other languages
English (en)
Inventor
Janusz Wojtowicz
Geoffrey Dahlhoff
Douglas W Grunewald
Thomas A Conner
Original Assignee
Life Technologies Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Technologies Corp filed Critical Life Technologies Corp
Publication of SG178411A1 publication Critical patent/SG178411A1/en

Links

Classifications

    • HELECTRICITY
    • H10SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10WGENERIC PACKAGES, INTERCONNECTIONS, CONNECTORS OR OTHER CONSTRUCTIONAL DETAILS OF DEVICES COVERED BY CLASS H10
    • H10W40/00Arrangements for thermal protection or thermal control
    • H10W40/01Manufacture or treatment
    • H10W40/03Manufacture or treatment of arrangements for cooling
    • H10W40/037Assembling together parts thereof
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • HELECTRICITY
    • H10SEMICONDUCTOR DEVICES; ELECTRIC SOLID-STATE DEVICES NOT OTHERWISE PROVIDED FOR
    • H10WGENERIC PACKAGES, INTERCONNECTIONS, CONNECTORS OR OTHER CONSTRUCTIONAL DETAILS OF DEVICES COVERED BY CLASS H10
    • H10W40/00Arrangements for thermal protection or thermal control
    • H10W40/40Arrangements for thermal protection or thermal control involving heat exchange by flowing fluids
    • H10W40/43Arrangements for thermal protection or thermal control involving heat exchange by flowing fluids by flowing gases, e.g. forced air cooling
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0829Multi-well plates; Microtitration plates
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1805Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1822Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using Peltier elements
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F28HEAT EXCHANGE IN GENERAL
    • F28DHEAT-EXCHANGE APPARATUS, NOT PROVIDED FOR IN ANOTHER SUBCLASS, IN WHICH THE HEAT-EXCHANGE MEDIA DO NOT COME INTO DIRECT CONTACT
    • F28D21/00Heat-exchange apparatus not covered by any of the groups F28D1/00 - F28D20/00
    • F28D2021/0019Other heat exchangers for particular applications; Heat exchange systems not otherwise provided for
    • F28D2021/0028Other heat exchangers for particular applications; Heat exchange systems not otherwise provided for for cooling heat generating elements, e.g. for cooling electronic components or electric devices
    • F28D2021/0029Heat sinks

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials Using Thermal Means (AREA)
  • Cooling Or The Like Of Semiconductors Or Solid State Devices (AREA)
  • Cooling Or The Like Of Electrical Apparatus (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
SG2012010278A 2009-09-01 2010-09-01 Thermal block assemblies and instruments providing low thermal non-uniformity for rapid thermal cycling SG178411A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23901209P 2009-09-01 2009-09-01
PCT/US2010/047573 WO2011028834A2 (en) 2009-09-01 2010-09-01 Thermal block assemblies and instruments providing low thermal non-uniformity for rapid thermal cycling

Publications (1)

Publication Number Publication Date
SG178411A1 true SG178411A1 (en) 2012-04-27

Family

ID=43646772

Family Applications (1)

Application Number Title Priority Date Filing Date
SG2012010278A SG178411A1 (en) 2009-09-01 2010-09-01 Thermal block assemblies and instruments providing low thermal non-uniformity for rapid thermal cycling

Country Status (7)

Country Link
US (2) US10049895B2 (https=)
EP (1) EP2473893B1 (https=)
JP (2) JP5781513B2 (https=)
CN (1) CN102483642B (https=)
IN (1) IN2012DN02105A (https=)
SG (1) SG178411A1 (https=)
WO (1) WO2011028834A2 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG184539A1 (en) 2010-04-09 2012-11-29 Life Technologies Corp Improved thermal uniformity for thermal cycler instrumentation using dynamic control
CA2922854A1 (en) * 2013-09-16 2015-03-19 Life Technologies Corporation Apparatuses, systems and methods for providing thermocycler thermal uniformity
RU2016134378A (ru) 2014-02-18 2018-03-22 Лайф Текнолоджиз Корпорейшн Устройства, системы и способы для создания термоциклеров в масштабируемом исполнении и изолирования термоэлектрических устройств
US11003808B2 (en) * 2015-09-30 2021-05-11 Siemens Industry Software Inc. Subtractive design for heat sink improvement
US11150032B2 (en) 2017-01-18 2021-10-19 Bigz Tech Inc. Transient heat absorption and delayed dissipation by high heat capacity material
GB201812192D0 (en) * 2018-07-26 2018-09-12 Ttp Plc Variable temperature reactor, heater and control circuit for the same
WO2020150007A1 (en) 2019-01-14 2020-07-23 Bio-Rad Laboratories, Inc. Heat pump device and assembly
US20220184612A1 (en) * 2019-03-18 2022-06-16 Seegene, Inc. Thermal cycler comprising sample holder assembly
CN212084987U (zh) * 2020-07-09 2020-12-04 宁波市哈雷换热设备有限公司 一种承压能力强的芯片冷却器
KR20240056761A (ko) * 2021-10-29 2024-04-30 주식회사 씨젠 열블록

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3566959A (en) * 1969-07-17 1971-03-02 Controlled Power Corp Heat sink
US3841853A (en) * 1972-09-05 1974-10-15 Owens Corning Fiberglass Corp Apparatus for production of thermoplastic materials
US4602651A (en) * 1978-05-30 1986-07-29 Roppatte Jr Michael Liquid applicator device with hair-parting wand
US4345837A (en) * 1980-06-27 1982-08-24 Farrand Optical Co., Inc. Enhanced fluorescent emission
US5038852A (en) * 1986-02-25 1991-08-13 Cetus Corporation Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
GB8606641D0 (en) * 1986-03-18 1986-04-23 British Petroleum Co Plc Testing device
US4753290A (en) * 1986-07-18 1988-06-28 Unisys Corporation Reduced-stress heat sink device
KR100236506B1 (ko) * 1990-11-29 2000-01-15 퍼킨-엘머시터스인스트루먼츠 폴리머라제 연쇄 반응 수행 장치
US6703236B2 (en) * 1990-11-29 2004-03-09 Applera Corporation Thermal cycler for automatic performance of the polymerase chain reaction with close temperature control
US5318361A (en) * 1993-06-01 1994-06-07 Bell Communications Research, Inc. Rapid temperature cycling for accelerated stress testing
CA2130013C (en) * 1993-09-10 1999-03-30 Rolf Moser Apparatus for automatic performance of temperature cycles
US5525300A (en) * 1993-10-20 1996-06-11 Stratagene Thermal cycler including a temperature gradient block
US5849208A (en) * 1995-09-07 1998-12-15 Microfab Technoologies, Inc. Making apparatus for conducting biochemical analyses
US6039471A (en) * 1996-05-22 2000-03-21 Integrated Device Technology, Inc. Device for simulating dissipation of thermal power by a board supporting an electronic component
US7133726B1 (en) * 1997-03-28 2006-11-07 Applera Corporation Thermal cycler for PCR
WO1998043740A2 (en) 1997-03-28 1998-10-08 The Perkin-Elmer Corporation Improvements in thermal cycler for pcr
US6301779B1 (en) * 1998-10-29 2001-10-16 Advanced Thermal Solutions, Inc. Method for fabricating a heat sink having nested extended surfaces
GB9826237D0 (en) * 1998-11-30 1999-01-20 Hybaid Ltd Thermal cycler
EP1045038A1 (en) * 1999-04-08 2000-10-18 Hans-Knöll-Institut Für Naturstoff-Forschung E.V. Rapid heat block thermocycler
US6337435B1 (en) * 1999-07-30 2002-01-08 Bio-Rad Laboratories, Inc. Temperature control for multi-vessel reaction apparatus
US6657169B2 (en) * 1999-07-30 2003-12-02 Stratagene Apparatus for thermally cycling samples of biological material with substantial temperature uniformity
US6496373B1 (en) * 1999-11-04 2002-12-17 Amerasia International Technology, Inc. Compressible thermally-conductive interface
TW487298U (en) * 2000-12-19 2002-05-11 Global Win Technology Co Ltd Non-uniform heat dissipation fins
US6677151B2 (en) * 2002-01-30 2004-01-13 Applera Corporation Device and method for thermal cycling
US6659638B1 (en) * 2002-05-17 2003-12-09 Atlas Material Testing Technology, L.L.C. Dynamic temperature controlled accelerated weathering test apparatus
US6730883B2 (en) * 2002-10-02 2004-05-04 Stratagene Flexible heating cover assembly for thermal cycling of samples of biological material
US7079394B2 (en) * 2003-01-08 2006-07-18 Lenovo (Singapore) Pte. Ltd. Compact cooling device
US20040241048A1 (en) * 2003-05-30 2004-12-02 Applera Corporation Thermal cycling apparatus and method for providing thermal uniformity
US6874566B1 (en) * 2003-09-19 2005-04-05 Dell Products L.P. Heat sink with intermediate fan element
US7051536B1 (en) * 2004-11-12 2006-05-30 Bio-Rad Laboratories, Inc. Thermal cycler with protection from atmospheric moisture
US7274571B2 (en) * 2005-03-08 2007-09-25 Intel Corporation Heatsink
US7213636B2 (en) * 2005-03-15 2007-05-08 Delphi Technologies, Inc. Cooling assembly with impingement cooled heat sink
ES2401437T3 (es) * 2005-04-04 2013-04-19 Roche Diagnostics Gmbh Termociclado de un bloque que comprende múltiples muestras
US7472742B2 (en) * 2005-12-01 2009-01-06 General Electric Company Heat sink assembly
US7251136B2 (en) 2005-12-29 2007-07-31 Fu Zhun Precision Industry (Shen Zhen) Co., Ltd. Heat dissipation device having a ventilating duct
JP2007329253A (ja) * 2006-06-07 2007-12-20 Toyota Industries Corp 電子機器の冷却構造
US7629124B2 (en) * 2006-06-30 2009-12-08 Canon U.S. Life Sciences, Inc. Real-time PCR in micro-channels
US8962306B2 (en) * 2006-09-08 2015-02-24 Thermo Fisher Scientific Oy Instruments and method relating to thermal cycling
US20080128118A1 (en) * 2006-12-01 2008-06-05 Foxconn Technology Co., Ltd. Heat dissipation device with a heat pipe
US9920939B2 (en) 2007-01-22 2018-03-20 Klas C. Haglid Dehumidifer/cooler and method
WO2008091626A1 (en) 2007-01-22 2008-07-31 Wafergen, Inc. Apparatus for high throughput chemical reactions
US20080266806A1 (en) * 2007-04-27 2008-10-30 Lakin Eric D Electronic assembly that includes a heat sink which cools multiple electronic components
US20090139311A1 (en) 2007-10-05 2009-06-04 Applied Biosystems Inc. Biological Analysis Systems, Devices, and Methods
WO2009105499A1 (en) * 2008-02-20 2009-08-27 Termaat Joel R Thermocycler and sample vessel for rapid amplification of dna
CN201230438Y (zh) * 2008-07-07 2009-04-29 鸿富锦精密工业(深圳)有限公司 散热装置组合
WO2011087117A1 (ja) * 2010-01-18 2011-07-21 古河電気工業株式会社 ヒートシンク
US20130032323A1 (en) * 2011-08-02 2013-02-07 Hsu Takeho Heat sink structure
FR3062460B1 (fr) * 2017-02-01 2020-11-13 Valeo Vision Module lumineux pour projecteur de vehicule

Also Published As

Publication number Publication date
JP2013504181A (ja) 2013-02-04
EP2473893A4 (en) 2017-03-01
WO2011028834A2 (en) 2011-03-10
WO2011028834A3 (en) 2011-07-07
CN102483642B (zh) 2014-12-24
IN2012DN02105A (https=) 2015-08-21
JP5781513B2 (ja) 2015-09-24
CN102483642A (zh) 2012-05-30
US10049895B2 (en) 2018-08-14
EP2473893B1 (en) 2021-07-28
US20110056661A1 (en) 2011-03-10
EP2473893A2 (en) 2012-07-11
JP2014158505A (ja) 2014-09-04
US20180350628A1 (en) 2018-12-06

Similar Documents

Publication Publication Date Title
EP2473893B1 (en) Thermal block assemblies and instruments providing low thermal non-uniformity for rapid thermal cycling
CN103411996B (zh) 固体材料导热系数测量装置及测量方法
JP2008278896A (ja) Pcrのための熱サイクラの改良
Chiang Modeling and optimization of designing parameters for a parallel-plain fin heat sink with confined impinging jet using the response surface methodology
JP6951371B2 (ja) 生物学的適用のための制御系および方法
US8641271B2 (en) Method for testing heat pipes
Das Estimation of parameters in a fin with temperature-dependent thermal conductivity and radiation
Hotta et al. Experiment driven ANN-GA based technique for optimal distribution of discrete heat sources under mixed convection
Shailesh et al. Understanding the reliability of LED luminaires
JP2002310965A (ja) 分散配置された熱抵抗器を有する熱分析アセンブリ、および、種々の冷却装置を取り付けるための一体化フランジ
Jiang et al. A non-invasive multipoint product temperature measurement for pharmaceutical lyophilization
Luo et al. Feature analysis aided design of lightweight heat sink from network structures
Pinheiro Ramos et al. A heat flux-corrected experimental inverse technique for simultaneously estimating the thermal properties of a metallic medium as functions of temperature
Kowal et al. Long‐term stability of meteorological temperature sensors
Naya et al. Statistical functional approach for interlaboratory studies with thermal data
Binninger et al. Customized measuring station for Peltier modules
Yun et al. Development and calibration of reduced-size plate thermometer for measuring incident heat flux
Basak et al. Authentication of thermal tomographic images using histogram similarity detection techniques
Vaz Jr et al. Conjugated heat and mass transfer in convective drying in compact wood kilns: a system approach
Frankman et al. Investigation of lightpipe volumetric radiation effects in RTP thermometry
Safak et al. Experimental investigation of natural convection heat transfer from functionally graded annular fins on an inclined cylinder
JP6465582B2 (ja) 断熱容器内の温度算出装置、方法及びコンピュータプログラム
Li et al. Simulation analysis of temperature field characteristics of fast nucleic acid analyzer based on finite element method
Ahmed et al. Geometric Optimization of SLM-Printed AlSi10Mg Radial Heat Sinks: A Numerical and Experimental Approach for Natural Convection Conditions
Tarcin et al. Rapid heating and cooling chamber for a photonics junction measurement system