SG161218A1 - Supplemented matrices for the repair of bone fractures - Google Patents

Supplemented matrices for the repair of bone fractures

Info

Publication number
SG161218A1
SG161218A1 SG201002289-5A SG2010022895A SG161218A1 SG 161218 A1 SG161218 A1 SG 161218A1 SG 2010022895 A SG2010022895 A SG 2010022895A SG 161218 A1 SG161218 A1 SG 161218A1
Authority
SG
Singapore
Prior art keywords
pth
matrices
bone fractures
incorporated
matrix
Prior art date
Application number
SG201002289-5A
Other languages
English (en)
Inventor
Jason Schense
John Watson
Isabelle Arrighi
Original Assignee
Kuros Biosurgery Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kuros Biosurgery Ag filed Critical Kuros Biosurgery Ag
Publication of SG161218A1 publication Critical patent/SG161218A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/29Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02Inorganic materials
    • A61L27/12Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/225Fibrin; Fibrinogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00Materials or treatment for tissue regeneration
    • A61L2430/02Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Materials Engineering (AREA)
  • Composite Materials (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SG201002289-5A 2005-01-06 2006-01-06 Supplemented matrices for the repair of bone fractures SG161218A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64171505P 2005-01-06 2005-01-06
US64264405P 2005-01-10 2005-01-10

Publications (1)

Publication Number Publication Date
SG161218A1 true SG161218A1 (en) 2010-05-27

Family

ID=36581768

Family Applications (1)

Application Number Title Priority Date Filing Date
SG201002289-5A SG161218A1 (en) 2005-01-06 2006-01-06 Supplemented matrices for the repair of bone fractures

Country Status (12)

Country Link
US (1) US20060148704A1 (fr)
EP (3) EP3111966B1 (fr)
JP (2) JP5328153B2 (fr)
KR (1) KR20070108170A (fr)
AU (1) AU2006204461C1 (fr)
BR (1) BRPI0606409A2 (fr)
CA (1) CA2592973A1 (fr)
ES (2) ES2902872T3 (fr)
MX (1) MX2007008319A (fr)
RU (1) RU2422172C2 (fr)
SG (1) SG161218A1 (fr)
WO (1) WO2006072622A2 (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8852240B2 (en) 2004-10-25 2014-10-07 Kieran Murphy, Llc Methods and compositions for fostering and preserving bone growth
US8575101B2 (en) 2005-01-06 2013-11-05 Kuros Biosurgery Ag Supplemented matrices for the repair of bone fractures
ES2359526T3 (es) 2006-05-26 2011-05-24 Baxter International Inc. Agente inyectable para el relleno de huecos óseos.
DE602007012693D1 (de) 2006-05-26 2011-04-07 Baxter Healthcare Sa Injizierbare fibrin-zusammensetzung zur knochenverstärkung
US9066994B2 (en) * 2006-08-31 2015-06-30 Warsaw Orthopedic, Inc. Demineralized cancellous strip DBM graft
US8388626B2 (en) * 2006-11-08 2013-03-05 Warsaw Orthopedic, Inc. Methods of employing calcium phosphate cement compositions and osteoinductive proteins to effect vertebrae interbody fusion absent an interbody device
SI3345607T1 (sl) * 2006-12-29 2023-03-31 Ossifi-Mab Llc Postopki spreminjanja rasti kosti z dajanjem antagonista ali agonista SOST ali WISE
JP5385257B2 (ja) 2007-03-26 2014-01-08 バクスター・インターナショナル・インコーポレイテッド 軟部組織増強のための注入可能な空隙の充填剤
CA2686820C (fr) * 2007-04-23 2016-06-28 Baxter International Inc. Compositions de fibrine contenant des composes de strontium
CA2685407A1 (fr) * 2007-04-27 2008-11-06 Yale University Procedes et compositions destines a stimuler et a preserver la croissance osseuse
WO2008157608A1 (fr) * 2007-06-18 2008-12-24 Cartlix, Inc. Echafaudages composites pour la régénération tissulaire
CA2702190A1 (fr) * 2007-10-12 2009-04-16 Kuros Biosurgery Ag Compositions radio-opaques injectables pour une augmentation de tissu
EP2227263A2 (fr) * 2007-12-28 2010-09-15 Kuros Biosurgery AG Protéines hybrides du pdgf incorporées dans des mousses de fibrine
EP2279021B1 (fr) 2008-04-18 2013-02-13 Kuros Biosurgery AG Dispositif de distribution, ensemble contenant le dispositif, et procédé d'utilisation du dispositif
WO2011031476A2 (fr) * 2009-08-25 2011-03-17 Emory University Compositions et méthodes pour le traitement ou la prévention d'une inflammation post-opératoire d'un organe ou d'un tissu
KR101114773B1 (ko) * 2009-10-23 2012-03-05 세원셀론텍(주) 연골조직 수복용 조성물의 제조방법
ES2882852T3 (es) 2011-03-16 2021-12-02 Kuros Biosurgery Ag Formulación farmacéutica para la utilización en la fusión espinal
US8404256B2 (en) * 2011-05-06 2013-03-26 The University Of Memphis Research Foundation Biomaterial composite composition and method of use
RU2563992C2 (ru) * 2013-08-12 2015-09-27 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет имени М.В. Ломоносова" (МГУ) Композитные матриксы на основе фиброина шелка, желатина и гидроксиапатита для регенерации костной ткани
EP3536353A1 (fr) * 2018-03-09 2019-09-11 Kuros Biosurgery AG Procédé et kits de production d'une matrice de fibrine
RU2702520C1 (ru) * 2019-04-17 2019-10-08 Анна Владимировна Алабут Способ эндопротезирования коленного сустава у пациентов с остеопорозом
RU2764373C1 (ru) * 2021-03-29 2022-01-17 Федеральное государственное бюджетное военное образовательное учреждение высшего образования "Военно-медицинская академия имени С.М. Кирова" Министерства обороны Российской Федерации (ВМедА) Способ применения ген-активированного материала при несращениях длинных костей

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4086196A (en) 1975-03-28 1978-04-25 Armour Pharmaceutical Company Parathyroid hormone
SE8200751L (sv) * 1982-02-09 1983-08-10 Olle Larm Forfarande for kovalent koppling for framstellning av konjugat och hervid erhallna produkter
IL74617A (en) * 1985-03-15 1988-11-15 Yeda Res & Dev Compositions comprising a vitamin d derivative and method for the local treatment of bone fractures in animals
US5504001A (en) * 1987-11-25 1996-04-02 Zymogenetics, Inc. Hybrid plasminogen activator
US5582862A (en) * 1988-04-04 1996-12-10 General Hospital Corporation Antibodies that bind to α2-antiplasmin crosslinked to fibrin which do not inhibit plasma α2-antiplasmin
US5100668A (en) * 1988-06-14 1992-03-31 Massachusetts Institute Of Technology Controlled release systems containing heparin and growth factors
US5137819A (en) * 1988-07-08 1992-08-11 University Of British Columbia Cellulose binding fusion proteins for immobilization and purification of polypeptides
US5171670A (en) * 1989-05-12 1992-12-15 The General Hospital Corporation Recombinant dna method for production of parathyroid hormone
US6054122A (en) * 1990-11-27 2000-04-25 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6117425A (en) * 1990-11-27 2000-09-12 The American National Red Cross Supplemented and unsupplemented tissue sealants, method of their production and use
US6197325B1 (en) * 1990-11-27 2001-03-06 The American National Red Cross Supplemented and unsupplemented tissue sealants, methods of their production and use
US6559119B1 (en) * 1990-11-27 2003-05-06 Loyola University Of Chicago Method of preparing a tissue sealant-treated biomedical material
SE470006B (sv) * 1991-09-26 1993-10-25 Corline Systems Ab Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet
US5641670A (en) * 1991-11-05 1997-06-24 Transkaryotic Therapies, Inc. Protein production and protein delivery
US5814603A (en) * 1992-06-12 1998-09-29 Affymax Technologies N.V. Compounds with PTH activity
US5589452A (en) * 1992-07-14 1996-12-31 Syntex (U.S.A.) Inc. Analogs of parathyroid hormone and parathyroid hormone related peptide: synthesis and use for the treatment of osteoporosis
US5428014A (en) * 1993-08-13 1995-06-27 Zymogenetics, Inc. Transglutaminase cross-linkable polypeptides and methods relating thereto
US5773577A (en) * 1994-03-03 1998-06-30 Protein Polymer Technologies Products comprising substrates capable of enzymatic cross-linking
US5747456A (en) * 1994-12-19 1998-05-05 Beth Israel Deaconess Medical Center Continuous low-dose administration of parathyroid hormone or its agonist
US5693341A (en) * 1995-03-16 1997-12-02 Collagen Corporation Affinity bound collagen matrices for the delivery of biologically active agents
US5561983A (en) * 1995-07-10 1996-10-08 Caire, Inc. Cryogenic liquid delivery system
JP2000500019A (ja) * 1995-11-16 2000-01-11 ロシュ ダイアグノスティクス ゲゼルシャフト ミット ベシュレンクテル ハフツング ストレプトアビジン融合タンパク質経由でのペプチドの生産方法
ES2420106T3 (es) * 1995-12-18 2013-08-22 Angiodevice International Gmbh Composiciones de polímeros reticulados y métodos para su uso
US5874308A (en) * 1996-01-16 1999-02-23 University Of British Columbia Compositions and methods for modulating cell proliferation using growth factor-polysaccharide binding fusion proteins
US6221854B1 (en) * 1996-03-05 2001-04-24 Orquest, Inc. Method of promoting bone growth with hyaluronic acid and growth factors
US5877153A (en) * 1996-06-11 1999-03-02 Commonwealth Biotechnologies Inc. Heparin-binding peptides
GB2348426B (en) 1997-04-03 2001-06-27 California Inst Of Techn Enzyme-mediated modification of fibrin for tissue engineering
US20020168718A1 (en) * 1997-04-03 2002-11-14 California Institute Of Technology Enzyme-mediated modification of fibrin for tissue engineering
US5958874A (en) * 1998-02-18 1999-09-28 The Research Foundation Of State University Of New York Recombinant fibronectin-based extracellular matrix for wound healing
DE19816858A1 (de) * 1998-04-16 1999-10-21 Merck Patent Gmbh Tricalciumphosphathaltige Biozementpasten mit Kohäsionspromotoren
US7241730B2 (en) * 1998-08-27 2007-07-10 Universitat Zurich Enzyme-mediated modification of fibrin for tissue engineering: fibrin formulations with peptides
US7601685B2 (en) * 1998-08-27 2009-10-13 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
US6894022B1 (en) * 1998-08-27 2005-05-17 Eidgenossische Technische Hochschule Zurich Growth factor modified protein matrices for tissue engineering
US6663870B2 (en) * 1998-12-07 2003-12-16 Zymogenetics, Inc. Methods for promoting growth of bone using zvegf3
US6468543B1 (en) * 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
US6303138B1 (en) * 1999-09-17 2001-10-16 Depuy Orthopaedics Endothelin-based compositions for enhancing connective tissue repair
US7052856B2 (en) * 1999-10-05 2006-05-30 The Regents Of The University Of California NELL-1 enhanced bone mineralization
US6608293B2 (en) * 1999-12-17 2003-08-19 Agilent Technologies Inc. Method of and apparatus for testing a photosensor
US6811776B2 (en) * 2000-12-27 2004-11-02 The Regents Of The University Of Michigan Process for ex vivo formation of mammalian bone and uses thereof
US6949251B2 (en) * 2001-03-02 2005-09-27 Stryker Corporation Porous β-tricalcium phosphate granules for regeneration of bone tissue
CA2367636C (fr) * 2001-04-12 2010-05-04 Lisa Mckerracher Proteines de fusion
EP1406678B1 (fr) * 2001-04-25 2009-01-14 Eidgenössische Technische Hochschule Zürich Matrices pour l'administration de medicaments destinees a ameliorer la cicatrisation
US20070264227A1 (en) * 2001-11-07 2007-11-15 Eidgenossische Technische Hochschule Zurich Synthetic Matrix for Controlled Cell Ingrowth and Tissue Regeneration
BR0213937A (pt) * 2001-11-07 2004-10-26 Univ Zuerich Matriz sintética para encravamento celular controlado e regeneração de tecido
US7247609B2 (en) * 2001-12-18 2007-07-24 Universitat Zurich Growth factor modified protein matrices for tissue engineering
MXPA04006021A (es) * 2001-12-18 2005-08-19 Eth Zuerich Matrices de proteina modificada con factor de crecimiento para ingenieria de tejidos.
WO2003055418A1 (fr) * 2001-12-21 2003-07-10 Lagow Richard J Materiaux de substitution osseuse a base de phosphate de calcium et methodes d'utilisation desdits materiaux
CA2483778A1 (fr) * 2002-04-29 2003-11-13 Gel-Del Technologies, Inc. Systemes de fixation et de confinement structurels de matrices biologiques et procedes d'utilisation de ceux-ci
US20050010297A1 (en) * 2003-05-08 2005-01-13 Kuros Biosurgery Ag Balloon technologies for tissue repair
DE10355992A1 (de) * 2003-11-27 2005-06-30 Curasan Ag Bioresorbierbares Kompositmaterial
JP2008529972A (ja) * 2004-12-22 2008-08-07 クロス・バイオサージェリー・アクチェンゲゼルシャフト 酵素的に分解可能な連結を通じて生物活性因子が組み入れられている合成バイオマテリアル
WO2006073711A2 (fr) * 2005-01-06 2006-07-13 Kuros Biosurgery Ag Traitement local des deficits osseux
US20060168718A1 (en) * 2005-02-01 2006-08-03 Frederick Watson Urinal enclosure

Also Published As

Publication number Publication date
EP1833522B1 (fr) 2016-06-22
BRPI0606409A2 (pt) 2009-06-23
RU2422172C2 (ru) 2011-06-27
EP2316497A3 (fr) 2014-05-07
WO2006072622A3 (fr) 2006-11-23
RU2007129844A (ru) 2009-02-20
EP3111966A1 (fr) 2017-01-04
EP2316497A2 (fr) 2011-05-04
EP3111966B1 (fr) 2021-10-13
JP2013173770A (ja) 2013-09-05
WO2006072622A2 (fr) 2006-07-13
AU2006204461B2 (en) 2011-07-07
AU2006204461A1 (en) 2006-07-13
JP2008526810A (ja) 2008-07-24
EP1833522A2 (fr) 2007-09-19
AU2006204461C1 (en) 2012-01-12
ES2902872T3 (es) 2022-03-30
MX2007008319A (es) 2007-10-04
ES2593051T3 (es) 2016-12-05
US20060148704A1 (en) 2006-07-06
KR20070108170A (ko) 2007-11-08
JP5328153B2 (ja) 2013-10-30
CA2592973A1 (fr) 2006-07-13

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