SG156680A1 - Adrenocorticotropic hormone analogs and related methods - Google Patents
Adrenocorticotropic hormone analogs and related methodsInfo
- Publication number
- SG156680A1 SG156680A1 SG200907076-4A SG2009070764A SG156680A1 SG 156680 A1 SG156680 A1 SG 156680A1 SG 2009070764 A SG2009070764 A SG 2009070764A SG 156680 A1 SG156680 A1 SG 156680A1
- Authority
- SG
- Singapore
- Prior art keywords
- related methods
- adrenocorticotropic hormone
- hormone analogs
- analogs
- adrenocorticotropic
- Prior art date
Links
- IDLFZVILOHSSID-OVLDLUHVSA-N corticotropin Chemical class C([C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)NC(=O)[C@@H](N)CO)C1=CC=C(O)C=C1 IDLFZVILOHSSID-OVLDLUHVSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/695—Corticotropin [ACTH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- A61K38/35—Corticotropin [ACTH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/06—Antiabortive agents; Labour repressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/42—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of mineralocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62243604P | 2004-10-27 | 2004-10-27 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG156680A1 true SG156680A1 (en) | 2009-11-26 |
Family
ID=36336951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG200907076-4A SG156680A1 (en) | 2004-10-27 | 2005-10-27 | Adrenocorticotropic hormone analogs and related methods |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US7919577B2 (enExample) |
| EP (2) | EP1814574A4 (enExample) |
| JP (2) | JP2008518026A (enExample) |
| KR (3) | KR101242543B1 (enExample) |
| CN (2) | CN101947310A (enExample) |
| AU (2) | AU2005305157B2 (enExample) |
| CA (1) | CA2584221A1 (enExample) |
| IL (1) | IL182818A0 (enExample) |
| MX (1) | MX2007004676A (enExample) |
| NZ (1) | NZ554559A (enExample) |
| RU (2) | RU2407751C2 (enExample) |
| SG (1) | SG156680A1 (enExample) |
| WO (1) | WO2006052468A2 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101947310A (zh) | 2004-10-27 | 2011-01-19 | 丹佛大学 | 促肾上腺皮质激素类似物以及相关方法 |
| AU2008303919A1 (en) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Use of angiotensin II as a therapeutic agent in the treatment of eg S. pneumoniae infection |
| US8524664B2 (en) | 2011-06-02 | 2013-09-03 | Colorado Seminary, Which owns and Operates The Univeristy of Denver | Methods of treating overproduction of cortisol using ACTH antagonist peptides |
| US10233219B2 (en) | 2013-04-12 | 2019-03-19 | Tufts Medical Center | Methods and systems for designing and/or characterizing soluble lipidated ligand agents |
| CN104277105B (zh) * | 2013-07-12 | 2017-12-12 | 国家纳米科学中心 | 抑制β淀粉样蛋白聚集和毒性的多肽抑制剂及其应用 |
| CN103724427B (zh) * | 2013-11-29 | 2016-09-28 | 青岛康原药业有限公司 | 一种精制促皮质素的方法 |
| CN105899950B (zh) * | 2013-12-19 | 2017-11-24 | 根特大学 | 鱼鳞中作为对于慢性应激的生物标记物的糖皮质激素的量化 |
| WO2015127288A1 (en) | 2014-02-20 | 2015-08-27 | Alder Biopharmaceuticals, Inc. | Anti-acth antibodies and use thereof |
| EP3233916A4 (en) * | 2014-12-19 | 2018-06-06 | Alder Biopharmaceuticals, Inc. | Humanized anti-acth antibodies and use thereof |
| CN104530219A (zh) * | 2014-12-23 | 2015-04-22 | 青岛康原药业有限公司 | 一种精制促皮质素的方法 |
| AU2016249408A1 (en) | 2015-04-16 | 2017-11-09 | H. Lundbeck A/S. | Anti-PACAP antibodies and uses thereof |
| WO2017127827A1 (en) | 2016-01-22 | 2017-07-27 | Tufts Medical Center | Compounds and methods for treating inflammation |
| CN105669856A (zh) * | 2016-02-13 | 2016-06-15 | 王大勇 | 一种基因重组长效人促肾上腺皮质激素及其制备方法 |
| MA54832A (fr) | 2016-03-01 | 2021-12-01 | Immatics Biotechnologies Gmbh | Peptides, combinaison de peptides et médicaments à base de cellules destinés à être utilisés en immunothérapie contre le cancer de la vessie et d'autres cancers |
| JP2019515671A (ja) | 2016-04-15 | 2019-06-13 | アルダー バイオファーマシューティカルズ、インコーポレイテッド | 抗ｐａｃａｐ抗体及びそれらの使用 |
| CN106478771A (zh) * | 2016-10-09 | 2017-03-08 | 李世军 | 一种氨基酸神经四肽的合成方法 |
| US11338018B2 (en) | 2016-12-19 | 2022-05-24 | Harrow Ip, Llc | Adrenocorticotropic hormone-based pharmaceutical formulations and methods for fabricating and using thereof |
| WO2018118115A1 (en) * | 2016-12-19 | 2018-06-28 | Eton Pharmaceuticals, Inc. | Adrenocorticotropic hormone-based pharmaceutical formulations and methods for fabricating and using thereof |
| CN110698557B (zh) * | 2019-11-06 | 2021-06-18 | 郑州伊美诺生物技术有限公司 | Acth突变体、重组蛋白及其应用，以及含有该acth重组蛋白的试剂盒 |
| US12433936B2 (en) | 2021-04-12 | 2025-10-07 | Nanjing Hanxin Pharmaceutical Technology Co., Ltd. | High-purity adrenocorticotropic hormone analogue and a large-scale preparation method thereof |
| CN116761809A (zh) * | 2021-04-12 | 2023-09-15 | 南京汉欣医药科技有限公司 | 一种高纯的人促肾上腺皮质激素或其类似物及其规模化制备方法 |
| CN120420414A (zh) * | 2024-02-04 | 2025-08-05 | 南京汉欣医药科技有限公司 | 含有人工合成的促皮质素类似物的组合物、其制备方法以及其用途 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US6A (en) * | 1836-08-10 | Thomas Blanchard | Machine for forming end pieces of plank blocks for ships | |
| US4415546A (en) | 1981-05-12 | 1983-11-15 | Janakiraman Ramachandran | Biologically active analogs of ACTH and radioimmuno assay therefor |
| US4457864A (en) | 1981-10-23 | 1984-07-03 | University Patents, Inc. | Synthetic analogues of α-melanotropin |
| US4485039A (en) | 1982-06-11 | 1984-11-27 | University Patents, Inc. | Synthetic analogues of α-melanotropin |
| US4649191A (en) | 1984-05-10 | 1987-03-10 | Gibson-Stephens Neuropharmaceuticals, Inc. | Conformationally constrained alpha-melanotropin analogs with specific central nervous system activity |
| DE3783541T2 (de) | 1986-02-03 | 1993-06-17 | University Patents Inc | Verfahren zur stimulierung von melanozyten durch lokales anbringen von alpha-msh-analogen, sowie zusammensetzungen. |
| US5674839A (en) | 1987-05-22 | 1997-10-07 | Competitive Technologies, Inc. | Cyclic analogs of alpha-MSH fragments |
| US5049547A (en) | 1988-02-11 | 1991-09-17 | University Patents, Inc. | Composition for stimulating integumental melanocytes |
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| US5189018A (en) | 1991-08-19 | 1993-02-23 | Wayne State University | Method for reduction of central nervous system (cns) edema resulting from head and spinal cord trauma |
| ES2151541T3 (es) | 1992-12-02 | 2001-01-01 | Alkermes Inc | Microesferas que contienen hormona del crecimiento de liberacion prolongada. |
| EP0681491B1 (en) | 1993-01-29 | 2000-12-13 | Aradigm Corporation | Intrapulmonary delivery of hormones |
| US5558085A (en) | 1993-01-29 | 1996-09-24 | Aradigm Corporation | Intrapulmonary delivery of peptide drugs |
| US5554380A (en) | 1994-08-04 | 1996-09-10 | Kv Pharmaceutical Company | Bioadhesive pharmaceutical delivery system |
| BR9509201A (pt) | 1994-09-09 | 1997-12-30 | Takeda Chemical Industries Ltd | Preparação de liberação sustemtada uso de um sal de metal polivalente insolúvel em água ou ligeiramente solúvel em água e processo para produzir uma preparação de liberação sustentada |
| US5731408A (en) | 1995-04-10 | 1998-03-24 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Peptides having potent antagonist and agonist bioactivities at melanocortin receptors |
| EP0831787B1 (en) | 1995-06-07 | 2001-08-22 | Alkermes Controlled Therapeutics, Inc. | Composition for sustained release of human growth hormone |
| ZA965368B (en) | 1995-07-14 | 1997-01-14 | Novo Nordisk As | A pharmaceutical formulation |
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| GB9606016D0 (en) | 1996-03-22 | 1996-05-22 | Smithkline Beecham Plc | Novel use |
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| US5863560A (en) | 1996-09-11 | 1999-01-26 | Virotex Corporation | Compositions and methods for topical application of therapeutic agents |
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| US6056954A (en) | 1997-10-31 | 2000-05-02 | New Horizons Diagnostics Corp | Use of bacterial phage associated lysing enzymers for the prophylactic and therapeutic treatment of various illnesses |
| HUP0102693A3 (en) | 1998-06-26 | 2002-12-28 | Pfizer Prod Inc | Improved process for preparing schiff base adducts of amines with o-hydroxy aldehydes and compositions of matter based thereon |
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| IES990700A2 (en) | 1999-08-18 | 2001-08-22 | Kinerton Ltd | Process to make a sustained release formulation |
| US6056955A (en) | 1999-09-14 | 2000-05-02 | Fischetti; Vincent | Topical treatment of streptococcal infections |
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| US7229635B2 (en) | 2000-04-21 | 2007-06-12 | Indiana University Research And Technology Corporation | Pharmacotherapeutic process and composition for central nervous system disorders |
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| TWI228512B (en) | 2000-10-25 | 2005-03-01 | Mayo Foundation | Transcobalamin binding conjugates useful for treating abnormal cellular proliferation |
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| CA2534823A1 (en) | 2003-08-04 | 2005-02-24 | Alza Corporation | Method and device for enhancing transdermal agent flux |
| EP1689457A2 (en) | 2003-11-10 | 2006-08-16 | Angiotech International Ag | Intravascular devices and fibrosis-inducing agents |
| US20050147581A1 (en) | 2003-11-19 | 2005-07-07 | The Board Of Trustees Of The University Of Illinois | Macromolecular drug complexes having improved stability and therapeutic use of the same |
| CN101947310A (zh) | 2004-10-27 | 2011-01-19 | 丹佛大学 | 促肾上腺皮质激素类似物以及相关方法 |
-
2005
- 2005-10-27 CN CN2010102535012A patent/CN101947310A/zh active Pending
- 2005-10-27 EP EP05851264A patent/EP1814574A4/en not_active Withdrawn
- 2005-10-27 MX MX2007004676A patent/MX2007004676A/es active IP Right Grant
- 2005-10-27 US US11/666,485 patent/US7919577B2/en not_active Expired - Fee Related
- 2005-10-27 WO PCT/US2005/038789 patent/WO2006052468A2/en not_active Ceased
- 2005-10-27 CN CN2005800424277A patent/CN101189022B/zh not_active Expired - Fee Related
- 2005-10-27 CA CA002584221A patent/CA2584221A1/en not_active Abandoned
- 2005-10-27 KR KR1020127002771A patent/KR101242543B1/ko not_active Expired - Fee Related
- 2005-10-27 EP EP11185682A patent/EP2446894A3/en not_active Withdrawn
- 2005-10-27 NZ NZ554559A patent/NZ554559A/en not_active IP Right Cessation
- 2005-10-27 US US11/260,551 patent/US7264314B2/en not_active Expired - Fee Related
- 2005-10-27 KR KR1020077011532A patent/KR101058467B1/ko not_active Expired - Fee Related
- 2005-10-27 KR KR1020107020069A patent/KR101150242B1/ko not_active Expired - Fee Related
- 2005-10-27 JP JP2007539117A patent/JP2008518026A/ja not_active Ceased
- 2005-10-27 AU AU2005305157A patent/AU2005305157B2/en not_active Ceased
- 2005-10-27 SG SG200907076-4A patent/SG156680A1/en unknown
- 2005-10-27 RU RU2007119580/10A patent/RU2407751C2/ru not_active IP Right Cessation
-
2007
- 2007-01-19 US US11/655,600 patent/US20070197774A1/en not_active Abandoned
- 2007-04-26 IL IL182818A patent/IL182818A0/en unknown
-
2010
- 2010-05-11 US US12/778,027 patent/US20100260681A1/en not_active Abandoned
- 2010-08-24 RU RU2010135499/10A patent/RU2010135499A/ru not_active Application Discontinuation
-
2011
- 2011-04-28 AU AU2011201914A patent/AU2011201914A1/en not_active Abandoned
- 2011-09-09 JP JP2011197386A patent/JP2012067099A/ja active Pending
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