SG151284A1 - Antibodies against ccr5 and uses thereof - Google Patents
Antibodies against ccr5 and uses thereofInfo
- Publication number
- SG151284A1 SG151284A1 SG200901861-5A SG2009018615A SG151284A1 SG 151284 A1 SG151284 A1 SG 151284A1 SG 2009018615 A SG2009018615 A SG 2009018615A SG 151284 A1 SG151284 A1 SG 151284A1
- Authority
- SG
- Singapore
- Prior art keywords
- seq
- nos
- group
- antibodies against
- cdr2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/52—Constant or Fc region; Isotype
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Transplantation (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05007138 | 2005-04-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG151284A1 true SG151284A1 (en) | 2009-04-30 |
Family
ID=34934663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG200901861-5A SG151284A1 (en) | 2005-04-01 | 2006-03-31 | Antibodies against ccr5 and uses thereof |
Country Status (19)
Country | Link |
---|---|
US (1) | US7615216B2 (fr) |
EP (2) | EP2336183A3 (fr) |
JP (2) | JP4733736B2 (fr) |
KR (1) | KR20070116136A (fr) |
CN (1) | CN101175771A (fr) |
AR (1) | AR052959A1 (fr) |
AU (1) | AU2006228663A1 (fr) |
BR (1) | BRPI0609792A2 (fr) |
CA (1) | CA2603692A1 (fr) |
CR (1) | CR9393A (fr) |
IL (1) | IL186071A0 (fr) |
MA (1) | MA29374B1 (fr) |
MX (1) | MX2007011842A (fr) |
NO (1) | NO20074867L (fr) |
RU (1) | RU2007139953A (fr) |
SG (1) | SG151284A1 (fr) |
TW (1) | TW200720289A (fr) |
WO (1) | WO2006103100A2 (fr) |
ZA (1) | ZA200708332B (fr) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1981911A2 (fr) * | 2006-01-30 | 2008-10-22 | F.Hoffmann-La Roche Ag | Compositions synergiques destinees au traitement du vih |
TW200817438A (en) | 2006-08-17 | 2008-04-16 | Hoffmann La Roche | A conjugate of an antibody against CCR5 and an antifusogenic peptide |
MX2009002694A (es) | 2006-09-29 | 2009-03-24 | Hoffmann La Roche | Anticuerpos dirigidos contra ccr5 y usos de los mismos. |
CL2008000707A1 (es) | 2007-03-13 | 2008-09-22 | Hoffmann La Roche | Conjugado de polipeptidos antifusogenicos y polipeptidos derivados de la cabeza globular del factor del complemento c1q; composicion farmaceutica que lo comprende; su uso para tratar infecciones viricas; y metodo de produccion. |
US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
US9266967B2 (en) | 2007-12-21 | 2016-02-23 | Hoffmann-La Roche, Inc. | Bivalent, bispecific antibodies |
CN101918451A (zh) * | 2008-01-15 | 2010-12-15 | 弗·哈夫曼-拉罗切有限公司 | 抗CCR5的afucosylated抗体及其用途 |
WO2010028796A1 (fr) * | 2008-09-10 | 2010-03-18 | F. Hoffmann-La Roche Ag | Anticorps hexavalents trispécifiques |
WO2010028798A1 (fr) * | 2008-09-10 | 2010-03-18 | F. Hoffmann-La Roche Ag | Anticorps multivalents |
WO2010072381A1 (fr) | 2008-12-22 | 2010-07-01 | F. Hoffmann-La Roche Ag | Purification d'immunoglobuline |
PE20120591A1 (es) | 2009-04-02 | 2012-05-23 | Roche Glycart Ag | Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla |
US20100256340A1 (en) | 2009-04-07 | 2010-10-07 | Ulrich Brinkmann | Trivalent, bispecific antibodies |
MX2011011925A (es) | 2009-05-27 | 2011-12-06 | Hoffmann La Roche | Anticuerpos triespecificos o tetraespecificos. |
US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
TWI412375B (zh) | 2009-08-28 | 2013-10-21 | Roche Glycart Ag | 人類化抗cdcp1抗體 |
TW201113037A (en) | 2009-08-28 | 2011-04-16 | Hoffmann La Roche | Antibodies against CDCP1 for the treatment of cancer |
WO2011026640A1 (fr) | 2009-09-07 | 2011-03-10 | F. Hoffmann-La Roche Ag | Es-ms de glycopeptides pour analyse de glycosylation |
US20120302737A1 (en) | 2009-09-16 | 2012-11-29 | Genentech, Inc. | Coiled coil and/or tether containing protein complexes and uses thereof |
ES2571226T3 (es) | 2009-12-22 | 2016-05-24 | Roche Glycart Ag | Anticuerpos anti-HER3 y usos de los mismos |
TW201138821A (en) | 2010-03-26 | 2011-11-16 | Roche Glycart Ag | Bispecific antibodies |
WO2012010582A1 (fr) | 2010-07-21 | 2012-01-26 | Roche Glycart Ag | Anticorps anti-cxcr5 et leurs méthodes d'utilisation |
KR101586128B1 (ko) | 2010-08-24 | 2016-01-15 | 에프. 호프만-라 로슈 아게 | 디술피드 안정화 ― Fv 단편을 포함하는 이중특이적 항체 |
CN103154029B (zh) | 2010-10-05 | 2015-11-25 | 弗·哈夫曼-拉罗切有限公司 | 抗人tweak的抗体及其用途 |
JP5766296B2 (ja) | 2010-12-23 | 2015-08-19 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用 |
TW201238976A (en) * | 2011-02-23 | 2012-10-01 | Hoffmann La Roche | Antibodies against human IL33R and uses thereof |
EP2681240B1 (fr) | 2011-02-28 | 2017-08-16 | F. Hoffmann-La Roche AG | Protéines monovalentes de liaison à l'antigène |
RU2607038C2 (ru) | 2011-02-28 | 2017-01-10 | Ф. Хоффманн-Ля Рош Аг | Антигенсвязывающие белки |
WO2013024022A1 (fr) | 2011-08-12 | 2013-02-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Méthodes et compositions pharmaceutiques pour traiter l'hypertension pulmonaire |
BR112014006537A2 (pt) | 2011-09-23 | 2017-11-28 | Roche Glycart Ag | anticorpos biespecíficos, formulação farmacêutica, usos de um anticorpo biespecífico, método de tratamento, ácido nucleico, vetores de expressão, célula hospedeira e método para a produção de um anticorpo biespecífico |
US9365881B2 (en) | 2011-10-05 | 2016-06-14 | Hoffmann-La Roche Inc. | Process for antibody G1 glycoform production |
CN104105711B (zh) | 2012-02-10 | 2018-11-30 | 弗·哈夫曼-拉罗切有限公司 | 单链抗体及其他异多聚体 |
MX2014014162A (es) | 2012-05-24 | 2015-02-04 | Hoffmann La Roche | Anticuerpos multiespecificos. |
CN104395339A (zh) | 2012-06-27 | 2015-03-04 | 弗·哈夫曼-拉罗切有限公司 | 用于选择并产生含有至少两种不同结合实体的定制高度选择性和多特异性靶向实体的方法及其用途 |
CN104411718B (zh) | 2012-06-27 | 2018-04-24 | 弗·哈夫曼-拉罗切有限公司 | 用于制备包含特异性结合靶的至少一种结合实体的抗体Fc区缀合物的方法及其用途 |
AR094403A1 (es) | 2013-01-11 | 2015-07-29 | Hoffmann La Roche | Terapia de combinación de anticuerpos anti-her3 |
CN105612182B (zh) | 2013-10-11 | 2019-12-10 | 豪夫迈·罗氏有限公司 | 多特异性结构域交换共有可变轻链抗体 |
WO2015082446A1 (fr) | 2013-12-02 | 2015-06-11 | F. Hoffmann-La Roche Ag | Traitement du cancer à l'aide d'un anticorps anti-cdcp1 et d'un taxane |
UA117289C2 (uk) | 2014-04-02 | 2018-07-10 | Ф. Хоффманн-Ля Рош Аг | Мультиспецифічне антитіло |
EP3227332B1 (fr) | 2014-12-03 | 2019-11-06 | F.Hoffmann-La Roche Ag | Anticorps multi-spécifiques |
WO2018106945A1 (fr) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Procédés, dispositifs et systèmes de détection du tractus gastro-intestinal |
WO2018112264A1 (fr) | 2016-12-14 | 2018-06-21 | Progenity Inc. | Traitement d'une maladie du tractus gastro-intestinal avec une chimoikine/un inhibiteur du récepteur de chimiokine |
KR20210031898A (ko) | 2018-07-13 | 2021-03-23 | 난징 레전드 바이오테크 씨오., 엘티디. | 전염병을 치료하기 위한 공동수용체 시스템 |
WO2020106757A1 (fr) | 2018-11-19 | 2020-05-28 | Progenity, Inc. | Dispositif ingérable pour administrer un agent thérapeutique au tube digestif |
JP2023502725A (ja) * | 2019-11-21 | 2023-01-25 | ユニティ バイオテクノロジー インコーポレイテッド | Tie-2に対する抗体および使用方法 |
WO2021119482A1 (fr) | 2019-12-13 | 2021-06-17 | Progenity, Inc. | Dispositif ingérable pour administrer un agent thérapeutique dans le tractus gastro-intestinal |
US11629196B2 (en) | 2020-04-27 | 2023-04-18 | Incelldx, Inc. | Method of treating SARS-CoV-2-associated hypercytokinemia by administering a human monoclonal antibody (PRO-140) that inhibits CCR5/CCL5 binding interactions |
Family Cites Families (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
JPS6023084B2 (ja) * | 1979-07-11 | 1985-06-05 | 味の素株式会社 | 代用血液 |
US4640835A (en) * | 1981-10-30 | 1987-02-03 | Nippon Chemiphar Company, Ltd. | Plasminogen activator derivatives |
US4496689A (en) | 1983-12-27 | 1985-01-29 | Miles Laboratories, Inc. | Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer |
EP0206448B1 (fr) * | 1985-06-19 | 1990-11-14 | Ajinomoto Co., Inc. | Hémoglobine liée à un poly(oxyde d'alkylène) |
JPS63502716A (ja) | 1986-03-07 | 1988-10-13 | マサチューセッツ・インステチュート・オブ・テクノロジー | 糖タンパク安定性の強化方法 |
US4791192A (en) | 1986-06-26 | 1988-12-13 | Takeda Chemical Industries, Ltd. | Chemically modified protein with polyethyleneglycol |
JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・2・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
US5202238A (en) * | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
US5204244A (en) | 1987-10-27 | 1993-04-20 | Oncogen | Production of chimeric antibodies by homologous recombination |
US6743594B1 (en) * | 1995-06-06 | 2004-06-01 | Human Genome Sciences, Inc. | Methods of screening using human G-protein chemokine receptor HDGNR10 (CCR5) |
AU3375697A (en) * | 1996-05-28 | 1998-01-05 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Cc chemokine receptor 5, antibodies thereto, transgenic animals |
US6528625B1 (en) * | 1996-10-28 | 2003-03-04 | Millennium Pharmaceuticals, Inc. | Anti-CCR5 antibodies and kits comprising same |
JP2002512624A (ja) | 1997-05-21 | 2002-04-23 | バイオベーション リミテッド | 非免疫原性タンパク質の製造方法 |
US6610834B1 (en) | 1998-11-18 | 2003-08-26 | Peter I. Lobo | Human IgM antibodies to chemokine receptors |
US20030099645A1 (en) * | 2000-10-10 | 2003-05-29 | Lobo Peter Isaac | Naturally occuring IgM antibodies that bind to membrane receptors on lymphocytes |
AU776910B2 (en) | 1998-12-08 | 2004-09-23 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Modifying protein immunogenicity |
EP2088158A3 (fr) | 1998-12-16 | 2010-01-20 | Progenics Pharmaceuticals, Inc. | Anticorp monoclonal contre le récepteur CCR5 de chimokine. |
HUP0200484A2 (en) | 1999-03-11 | 2002-06-29 | Micromet Ag | Antibody and chemokine constructs that are directed to ccr5, and their use for treating autoimmune diseases |
US20030049251A1 (en) * | 1999-12-08 | 2003-03-13 | Barbas Carlos F. | Methods and compositions useful for inhibiting ccr5-dependent infection of cells by hiv-1 |
WO2001043779A2 (fr) | 1999-12-16 | 2001-06-21 | Tanox, Inc. | Conjugues anti-hiv1 pour le traitement du vih |
US20020048786A1 (en) * | 2000-02-09 | 2002-04-25 | Rosen Craig A. | Human G-protein Chemokine Receptor HDGNR10 |
US20040043033A1 (en) * | 2000-05-01 | 2004-03-04 | Green Lorrence H. | Method and vaccine for the prevention of AIDS |
US7138119B2 (en) | 2000-09-15 | 2006-11-21 | Progenics Pharmaceuticals, Inc. | Compositions and methods for inhibition of HIV-1 infection |
US20030165988A1 (en) * | 2002-02-08 | 2003-09-04 | Shaobing Hua | High throughput generation of human monoclonal antibody against peptide fragments derived from membrane proteins |
US7005503B2 (en) * | 2002-02-08 | 2006-02-28 | Genetastix Corporation | Human monoclonal antibody against coreceptors for human immunodeficiency virus |
EP1207202A1 (fr) | 2000-11-16 | 2002-05-22 | Mölling, Karin, Inst. für med. Virologie der Uni. Zürich | Molécules d'acide nucléique interagissant avec le récepteur de chémokines et d'autres membres de la famille de récepteurs de chémokines |
US20020147147A1 (en) * | 2000-11-16 | 2002-10-10 | Karin Molling | Nucleic acid molecules encoding a protein interacting with the chemokine receptor CCR5 or other chemokine receptor family members |
US7175988B2 (en) * | 2001-02-09 | 2007-02-13 | Human Genome Sciences, Inc. | Human G-protein Chemokine Receptor (CCR5) HDGNR10 |
US20030003440A1 (en) | 2001-03-14 | 2003-01-02 | Lucia Lopalco | Novel CCR5 epitope and antibodies against it |
US7060273B2 (en) | 2001-04-06 | 2006-06-13 | Progenics Pharmaceuticals, Inc. | Methods for inhibiting HIV-1 infection |
US20020146415A1 (en) | 2001-04-06 | 2002-10-10 | Olson William C. | Methods for inhibiting HIV-1 infection |
US7223844B2 (en) | 2001-10-16 | 2007-05-29 | United States Of America, Represented By The Secretary, Department Of Health And Human Services | Broadly cross-reactive neutralizing antibodies against human immunodeficiency virus selected by Env-CD4-co-receptor complexes |
WO2003066830A2 (fr) | 2002-02-08 | 2003-08-14 | Genetastix Corporation | Anticorps monoclonaux humains diriges contre des proteines membranaires |
PT1478738E (pt) * | 2002-02-22 | 2009-02-16 | Progenics Pharm Inc | Anticorpo anti-ccr5 |
US7122185B2 (en) | 2002-02-22 | 2006-10-17 | Progenics Pharmaceuticals, Inc. | Anti-CCR5 antibody |
-
2006
- 2006-03-29 TW TW095110965A patent/TW200720289A/zh unknown
- 2006-03-30 AR ARP060101255A patent/AR052959A1/es not_active Application Discontinuation
- 2006-03-31 AU AU2006228663A patent/AU2006228663A1/en not_active Abandoned
- 2006-03-31 JP JP2008503436A patent/JP4733736B2/ja not_active Expired - Fee Related
- 2006-03-31 CN CNA2006800170650A patent/CN101175771A/zh active Pending
- 2006-03-31 BR BRPI0609792-8A patent/BRPI0609792A2/pt not_active IP Right Cessation
- 2006-03-31 EP EP10191497A patent/EP2336183A3/fr not_active Withdrawn
- 2006-03-31 SG SG200901861-5A patent/SG151284A1/en unknown
- 2006-03-31 KR KR1020077024197A patent/KR20070116136A/ko not_active Application Discontinuation
- 2006-03-31 CA CA002603692A patent/CA2603692A1/fr not_active Abandoned
- 2006-03-31 WO PCT/EP2006/002974 patent/WO2006103100A2/fr active Application Filing
- 2006-03-31 EP EP06723934A patent/EP1869087A2/fr not_active Withdrawn
- 2006-03-31 RU RU2007139953/13A patent/RU2007139953A/ru not_active Application Discontinuation
- 2006-03-31 US US11/394,439 patent/US7615216B2/en not_active Expired - Fee Related
- 2006-03-31 MX MX2007011842A patent/MX2007011842A/es not_active Application Discontinuation
-
2007
- 2007-09-19 IL IL186071A patent/IL186071A0/en unknown
- 2007-09-24 CR CR9393A patent/CR9393A/es not_active Application Discontinuation
- 2007-09-25 NO NO20074867A patent/NO20074867L/no not_active Application Discontinuation
- 2007-09-27 MA MA30257A patent/MA29374B1/fr unknown
- 2007-09-28 ZA ZA200708332A patent/ZA200708332B/xx unknown
-
2010
- 2010-10-25 JP JP2010238172A patent/JP2011079836A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
TW200720289A (en) | 2007-06-01 |
KR20070116136A (ko) | 2007-12-06 |
WO2006103100A3 (fr) | 2006-12-28 |
MX2007011842A (es) | 2007-10-11 |
CA2603692A1 (fr) | 2006-10-05 |
CR9393A (es) | 2008-02-20 |
JP4733736B2 (ja) | 2011-07-27 |
EP1869087A2 (fr) | 2007-12-26 |
JP2008533998A (ja) | 2008-08-28 |
EP2336183A3 (fr) | 2011-10-12 |
NO20074867L (no) | 2007-12-07 |
RU2007139953A (ru) | 2009-05-10 |
AU2006228663A1 (en) | 2006-10-05 |
ZA200708332B (en) | 2009-04-29 |
US7615216B2 (en) | 2009-11-10 |
CN101175771A (zh) | 2008-05-07 |
US20070036796A1 (en) | 2007-02-15 |
WO2006103100A2 (fr) | 2006-10-05 |
MA29374B1 (fr) | 2008-04-01 |
IL186071A0 (en) | 2008-01-20 |
JP2011079836A (ja) | 2011-04-21 |
AR052959A1 (es) | 2007-04-11 |
BRPI0609792A2 (pt) | 2010-04-27 |
EP2336183A2 (fr) | 2011-06-22 |
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