SG144166A1 - Oligodendrocyte precursor cells and methods of obtaining and culturing the same - Google Patents

Oligodendrocyte precursor cells and methods of obtaining and culturing the same

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Publication number
SG144166A1
SG144166A1 SG200804940-5A SG2008049405A SG144166A1 SG 144166 A1 SG144166 A1 SG 144166A1 SG 2008049405 A SG2008049405 A SG 2008049405A SG 144166 A1 SG144166 A1 SG 144166A1
Authority
SG
Singapore
Prior art keywords
precursor cells
methods
oligodendrocyte precursor
obtaining
homogeneous population
Prior art date
Application number
SG200804940-5A
Other languages
English (en)
Inventor
Hiroshi Okazaki
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SG144166A1 publication Critical patent/SG144166A1/en

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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P31/20—Antivirals for DNA viruses
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/13—Nerve growth factor [NGF]; Brain-derived neurotrophic factor [BDNF]; Cilliary neurotrophic factor [CNTF]; Glial-derived neurotrophic factor [GDNF]; Neurotrophins [NT]; Neuregulins
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/135—Platelet-derived growth factor [PDGF]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/395—Thyroid hormones
    • C—CHEMISTRY; METALLURGY
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    • C12N2503/00—Use of cells in diagnostics
    • C12N2503/02—Drug screening
SG200804940-5A 2003-07-18 2004-07-19 Oligodendrocyte precursor cells and methods of obtaining and culturing the same SG144166A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48793303P 2003-07-18 2003-07-18

Publications (1)

Publication Number Publication Date
SG144166A1 true SG144166A1 (en) 2008-07-29

Family

ID=34079394

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200804940-5A SG144166A1 (en) 2003-07-18 2004-07-19 Oligodendrocyte precursor cells and methods of obtaining and culturing the same

Country Status (13)

Country Link
US (1) US20060172415A1 (es)
EP (1) EP1646711A4 (es)
JP (1) JP2007530001A (es)
KR (1) KR20060037346A (es)
CN (1) CN1833021A (es)
AR (1) AR046076A1 (es)
AU (1) AU2004257000B2 (es)
BR (1) BRPI0412715A (es)
CA (1) CA2532216A1 (es)
MX (1) MXPA05014161A (es)
SG (1) SG144166A1 (es)
TW (1) TW200510537A (es)
WO (1) WO2005007797A2 (es)

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EP1846578A4 (en) * 2005-02-11 2010-02-10 Elan Pharm Inc GENE IDENTIFICATION METHODS THAT MODULATE MYELINISATION
CN106177996A (zh) * 2005-06-23 2016-12-07 组织基因公司 神经保护性化合物
ES2323913B1 (es) * 2006-03-17 2010-05-14 Universidad De Salamanca (Titular Al 65%) Efecto mitogeno de sonic hedgehog (shh) sobre precursores de oligodendrocitos y su uso en enfermedades desmielinizantes.
SG188096A1 (en) 2008-01-30 2013-03-28 Geron Corp Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells
US8168433B2 (en) * 2008-01-30 2012-05-01 Corning Incorporated Cell culture article and screening
EP2247718B1 (en) * 2008-01-30 2019-01-16 Asterias Biotherapeutics, Inc. Synthetic surfaces for culturing stem cell derived cardiomyocytes
EP2355826A1 (en) * 2008-11-07 2011-08-17 The Cleveland Clinic Foundation Compounds and methods of promoting oligodendrocyte precursor differentiation
CN102686721B (zh) * 2009-11-12 2016-02-10 Q医疗公司 用于哺乳动物来源的神经胶质限制性祖细胞的扩增、鉴定、表征和效能增强的方法和组合物
CN101735983B (zh) * 2009-12-29 2011-07-27 中国人民解放军第三军医大学 少突胶质前体细胞的分离纯化方法
ES2375860B8 (es) * 2010-03-31 2013-06-10 Fundación Hospital Nacional De Parapléjicos Para La Investigación Y La Integración (Fuhnpaiin) Método para la obtención de células precursoras de oligodendrocitos.
JP2014528706A (ja) * 2011-08-07 2014-10-30 カディマステム リミテッド 成熟、生存及びミエリン形成に作用する薬剤を同定する方法
KR101409336B1 (ko) 2012-02-15 2014-06-27 중앙대학교 산학협력단 희돌기교전구세포를 유효성분으로 포함하는 중추신경계 질환의 치료용 조성물
EP2831222B1 (en) * 2012-03-27 2018-12-26 Okinawa Institute of Science and Technology Graduate University Neuronal culture medium and method for producing in vivo-like and enhanced synaptogenesis neuron model
US10180423B2 (en) * 2012-12-19 2019-01-15 The Regents Of The University Of California Micropillar arrays for assaying myelination
CN103388007B (zh) * 2013-07-25 2016-08-24 宗兆文 一种利用真皮来源的间充质干细胞制备组织工程脊髓的方法
JP6844953B2 (ja) * 2015-04-22 2021-03-17 公益財団法人東京都医学総合研究所 アルツハイマー病研究を標的にしたグリア細胞システム
CN105062956B (zh) * 2015-08-21 2018-02-09 北京市虹天济神经科学研究院 人嗅粘膜嗅鞘细胞分离、传代、冻存、分化技术
CN105695409B (zh) * 2016-03-22 2019-09-27 中国人民解放军第二军医大学 一种裸鼹鼠少突胶质前体细胞培养方法
US11920155B2 (en) 2016-03-30 2024-03-05 Asterias Biotherapeutics, Inc. Oligodendrocyte progenitor cell compositions
WO2018053210A1 (en) * 2016-09-14 2018-03-22 Asterias Biotherapeutics, Inc. Pluripotent stem cell-derived oligodendrocyte progenitor cells for the treatment of spinal cord injury
CN109722418B (zh) * 2017-10-29 2023-01-03 复旦大学 一种获取和纯化新生小鼠少突胶质前体细胞的方法
CN108624560B (zh) * 2018-06-01 2022-04-08 南京艾尔普再生医学科技有限公司 一种分化培养基及少突胶质前体细胞的制备方法
CN113481161A (zh) * 2021-07-30 2021-10-08 四川省医学科学院·四川省人民医院 一种培养基及少突胶质祖细胞的诱导培养方法以及应用
CN115340982A (zh) * 2022-08-23 2022-11-15 徐州医科大学 一种分离并纯化新生小鼠皮质区少突胶质前体细胞的方法

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US5753506A (en) * 1996-05-23 1998-05-19 Cns Stem Cell Technology, Inc. Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
US6361996B1 (en) * 1997-05-07 2002-03-26 University Of Utah Research Foundation Neuroepithelial stem cells and glial-restricted intermediate precursors
US6235527B1 (en) * 1997-11-29 2001-05-22 University Of Utah Research Foundation Lineage restricted glial precursors from the central nervous system
US6576464B2 (en) * 2000-11-27 2003-06-10 Geron Corporation Methods for providing differentiated stem cells
US20040029269A1 (en) * 2002-05-07 2004-02-12 Goldman Steven A Promoter-based isolation, purification, expansion, and transplantation of neuronal progenitor cells, oligodendrocyte progenitor cells, or neural stem cells from a population of embryonic stem cells
US7285415B2 (en) * 2002-07-11 2007-10-23 The Regents Of The University Of California Oligodendrocytes derived from human embryonic stem cells for remyelination and treatment of spinal cord injury

Also Published As

Publication number Publication date
AU2004257000B2 (en) 2011-07-21
WO2005007797A2 (en) 2005-01-27
CA2532216A1 (en) 2005-01-27
BRPI0412715A (pt) 2006-09-26
KR20060037346A (ko) 2006-05-03
EP1646711A4 (en) 2008-03-19
AU2004257000A1 (en) 2005-01-27
TW200510537A (en) 2005-03-16
MXPA05014161A (es) 2006-05-25
CN1833021A (zh) 2006-09-13
AR046076A1 (es) 2005-11-23
JP2007530001A (ja) 2007-11-01
US20060172415A1 (en) 2006-08-03
EP1646711A2 (en) 2006-04-19
WO2005007797A3 (en) 2006-05-11

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