SG118494G - Method of preventing or limiting reperfusion damage - Google Patents

Method of preventing or limiting reperfusion damage

Info

Publication number
SG118494G
SG118494G SG118494A SG118494A SG118494G SG 118494 G SG118494 G SG 118494G SG 118494 A SG118494 A SG 118494A SG 118494 A SG118494 A SG 118494A SG 118494 G SG118494 G SG 118494G
Authority
SG
Singapore
Prior art keywords
preventing
reperfusion damage
compound
limiting reperfusion
limiting
Prior art date
Application number
SG118494A
Other languages
English (en)
Inventor
Van Herman Belle
Van Willy J C Laverhoven
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to KR1019910700758A priority Critical patent/KR0165686B1/ko
Priority to CA002044143A priority patent/CA2044143C/fr
Priority to ES90917677T priority patent/ES2053208T3/es
Priority to AT90917677T priority patent/ATE102831T1/de
Priority to PCT/EP1990/001985 priority patent/WO1991007967A2/fr
Priority to EP19930201656 priority patent/EP0577171B1/fr
Priority to AT93201656T priority patent/ATE213943T1/de
Priority to DE69033926T priority patent/DE69033926T2/de
Priority to ES93201656T priority patent/ES2173883T3/es
Priority to AU68763/91A priority patent/AU632888B2/en
Priority to EP90917677A priority patent/EP0455789B1/fr
Priority to SU905001085A priority patent/RU2093156C1/ru
Priority to DK90917677.8T priority patent/DK0455789T3/da
Priority to JP3500097A priority patent/JP2574585B2/ja
Priority to DE69007471T priority patent/DE69007471T2/de
Priority to DK93201656T priority patent/DK0577171T3/da
Priority to IL9639090A priority patent/IL96390A/en
Priority to HU2436/91A priority patent/HU215847B/hu
Priority to NZ236168A priority patent/NZ236168A/xx
Priority to IE420990A priority patent/IE65121B1/en
Priority to ZA909345A priority patent/ZA909345B/xx
Priority to PT95959A priority patent/PT95959B/pt
Priority to NO912511A priority patent/NO304519B1/no
Priority to FI913433A priority patent/FI109694B/fi
Priority to SG118494A priority patent/SG118494G/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of SG118494G publication Critical patent/SG118494G/en
Priority to HK115095A priority patent/HK115095A/xx
Priority to CY186996A priority patent/CY1869A/xx
Priority to PT102145A priority patent/PT102145B/pt
Priority to NO19982078A priority patent/NO311701B1/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166—Streptokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49—Urokinase; Tissue plasminogen activator
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
SG118494A 1989-11-22 1994-08-20 Method of preventing or limiting reperfusion damage SG118494G (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
IL9639090A IL96390A (en) 1989-11-22 1990-11-19 Pharmacological preparations from the halls History of N-alkylpiperazinalalkanamide for the prevention or limitation of reproductive damage and some such new compounds and their preparation
DE69007471T DE69007471T2 (de) 1989-11-22 1990-11-19 Verfahren zur verhütung oder zur begrenzung einer reperfusionsschädigung.
AT90917677T ATE102831T1 (de) 1989-11-22 1990-11-19 Verfahren zur verhuetung oder zur begrenzung einer reperfusionsschaedigung.
PCT/EP1990/001985 WO1991007967A2 (fr) 1989-11-22 1990-11-19 Procede pour empecher ou limiter les lesions liees a la reperfusion
EP19930201656 EP0577171B1 (fr) 1989-11-22 1990-11-19 Utilisation de dérivés du pipérazine-acétamide contre les dégâts de la réperfusion
AT93201656T ATE213943T1 (de) 1989-11-22 1990-11-19 Verwendung von piperazin-acetamid-derivaten gegen reperfusionsschaden
DE69033926T DE69033926T2 (de) 1989-11-22 1990-11-19 Verwendung von Piperazin-Acetamid-Derivaten gegen Reperfusionsschaden
ES93201656T ES2173883T3 (es) 1989-11-22 1990-11-19 Utilizacion de derivados de piperacina-acetamida contra los daños de reperfusion.
AU68763/91A AU632888B2 (en) 1989-11-22 1990-11-19 Use of piperazine acetamide derivatives against reperfusion damage
EP90917677A EP0455789B1 (fr) 1989-11-22 1990-11-19 Procede pour empecher ou limiter les lesions liees a la reperfusion
CA002044143A CA2044143C (fr) 1989-11-22 1990-11-19 Methode visant a prevenir ou a limiter les dommages lies a la reproduction
DK90917677.8T DK0455789T3 (da) 1989-11-22 1990-11-19 Fremgangsmåde til forebyggelse eller begrænsning af reperfusionsbeskadigelse
JP3500097A JP2574585B2 (ja) 1989-11-22 1990-11-19 再潅流損傷の防止又は制限のための薬剤
KR1019910700758A KR0165686B1 (ko) 1989-11-22 1990-11-19 재관류 손상을 예방 또는 억제용 조성물
ES90917677T ES2053208T3 (es) 1989-11-22 1990-11-19 Metodo para prevenir o limitar el daño por reperfusion.
DK93201656T DK0577171T3 (da) 1989-11-22 1990-11-19 Anvendelse af piperazinacetamidderivater mod reperfusionsskader
HU2436/91A HU215847B (hu) 1989-11-22 1990-11-19 Eljárás N-fenil-piperazinacetamid-származékot tartalmazó, a véráramlás helyreállításakor bekövetkező károsodás megelőzésére vagy csökkentésére alkalmas gyógyászati készítmények és (1)-(-)-N-fenil-piperazinacetamid-származékok előállítására
SU905001085A RU2093156C1 (ru) 1989-11-22 1990-11-19 L-(-)-2-(аминокарбонил)-n-(4-амино-2,6-дихлорфенил-4[5,5-бис(4-фторфенил)пентил]-1-пиперазинацетамид, его фармацевтически приемлемая кислотно-аддитивная соль или гидрат, способ его получения и средство для хранения сердца донора
NZ236168A NZ236168A (en) 1989-11-22 1990-11-20 Stereochemically pure r- or s- piperazinealkanamides; pharmaceutical compositions, methods of treatment and preparation
ZA909345A ZA909345B (en) 1989-11-22 1990-11-21 Method of preventing or limiting reperfusion damage
IE420990A IE65121B1 (en) 1989-11-22 1990-11-21 Method of preventing or limiting reperfusion damage
PT95959A PT95959B (pt) 1989-11-22 1990-11-22 Processo para a preparacao de derivados de n-aril-piperazinoalcanamida e de composicoes farmaceuticas que os contem
NO912511A NO304519B1 (no) 1989-11-22 1991-06-26 Fremstilling av (1)-(-)-2-(aminokarbonyl)-N-(4-amino-2,6-diklorfenyl)-4-[5,5-bis(4-fluorfenyl)pentyl]-1-piperazinacetamid
FI913433A FI109694B (fi) 1989-11-22 1991-07-16 Menetelmä terapeuttisesti käyttökelpoisen (1)-(-)-2-(aminokarbonyyli)-N-(4-amino-2,6-dikloorifenyyli)-4-[5,5-bis-(4-fluorifenyyli)pentyyli]-1-piperatsiiniasetamidin valmistamiseksi
SG118494A SG118494G (en) 1989-11-22 1994-08-20 Method of preventing or limiting reperfusion damage
HK115095A HK115095A (en) 1989-11-22 1995-07-13 Method of preventing or limiting reperfusion damage
CY186996A CY1869A (en) 1989-11-22 1996-04-05 Method of preventing or limiting reperfusion damage
PT102145A PT102145B (pt) 1989-11-22 1998-04-20 Composicoes farmaceuticas a base de derivados de piperazina acetamida
NO19982078A NO311701B1 (no) 1989-11-22 1998-05-07 Fremgangsmåte for beskyttelse av et donorhjerte for transplantering samt anvendelse av en N-aryl-piperazinalkanamidforbindelse for dette formål

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44014289A 1989-11-22 1989-11-22
SG118494A SG118494G (en) 1989-11-22 1994-08-20 Method of preventing or limiting reperfusion damage

Publications (1)

Publication Number Publication Date
SG118494G true SG118494G (en) 1994-11-25

Family

ID=26664237

Family Applications (1)

Application Number Title Priority Date Filing Date
SG118494A SG118494G (en) 1989-11-22 1994-08-20 Method of preventing or limiting reperfusion damage

Country Status (22)

Country Link
EP (2) EP0455789B1 (fr)
JP (1) JP2574585B2 (fr)
KR (1) KR0165686B1 (fr)
AT (2) ATE102831T1 (fr)
AU (1) AU632888B2 (fr)
CA (1) CA2044143C (fr)
CY (1) CY1869A (fr)
DE (2) DE69007471T2 (fr)
DK (2) DK0577171T3 (fr)
ES (2) ES2053208T3 (fr)
FI (1) FI109694B (fr)
HK (1) HK115095A (fr)
HU (1) HU215847B (fr)
IE (1) IE65121B1 (fr)
IL (1) IL96390A (fr)
NO (2) NO304519B1 (fr)
NZ (1) NZ236168A (fr)
PT (2) PT95959B (fr)
RU (1) RU2093156C1 (fr)
SG (1) SG118494G (fr)
WO (1) WO1991007967A2 (fr)
ZA (1) ZA909345B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202266D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel piperazine carboxamides
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
ES2319876T3 (es) 2001-05-18 2009-05-14 Astrazeneca Ab Derivados de 4 (fenil-piperazinil-metil) benzamida y su uso para el tratamiento de la ansiedad o trastornos gastrointestinales.
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
CA2575975A1 (fr) * 2003-11-12 2005-05-26 Dr. Reddy's Laboratories, Inc. Preparation d'escitaloprame
MX2007001240A (es) 2004-08-02 2007-03-23 Astrazeneca Ab Derivados de diarilmetil-piperazina, preparaciones y usos de las mismas.
FR2946340B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux n-phenyl acetamie, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
KR101900124B1 (ko) 2014-06-25 2018-09-18 전남대학교산학협력단 전복 박리용 조성물
KR101644299B1 (ko) 2014-07-22 2016-08-02 주식회사 엔바이로젠 오미자 및 삼채 추출물을 유효성분으로 포함하는 전복 박리용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
NZ223847A (en) * 1987-04-01 1989-12-21 Janssen Pharmaceutica Nv Substituted piperazine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
FI109694B (fi) 2002-09-30
DK0577171T3 (da) 2002-06-03
HUT58709A (en) 1992-03-30
HU215847B (hu) 1999-04-28
ES2173883T3 (es) 2002-11-01
PT102145B (pt) 2002-06-28
RU2093156C1 (ru) 1997-10-20
KR920700644A (ko) 1992-08-10
ZA909345B (en) 1992-08-26
DE69007471D1 (de) 1994-04-21
EP0455789B1 (fr) 1994-03-16
KR0165686B1 (ko) 1999-01-15
IE65121B1 (en) 1995-10-04
PT95959B (pt) 1998-08-31
WO1991007967A2 (fr) 1991-06-13
ES2053208T3 (es) 1994-07-16
CA2044143A1 (fr) 1991-05-23
NZ236168A (en) 1993-05-26
NO982078D0 (no) 1998-05-07
EP0577171A3 (en) 1994-06-29
EP0577171B1 (fr) 2002-03-06
IL96390A (en) 1995-06-29
NO912511D0 (no) 1991-06-26
CY1869A (en) 1996-04-05
PT102145A (pt) 1999-10-29
FI913433A0 (fi) 1991-07-16
DK0455789T3 (da) 1994-04-05
NO311701B1 (no) 2002-01-14
EP0577171A2 (fr) 1994-01-05
IE904209A1 (en) 1991-05-22
ATE213943T1 (de) 2002-03-15
NO304519B1 (no) 1999-01-04
AU632888B2 (en) 1993-01-14
NO982078L (no) 1991-08-26
DE69033926T2 (de) 2002-10-24
AU6876391A (en) 1991-06-26
CA2044143C (fr) 2002-11-19
NO912511L (no) 1991-08-26
ATE102831T1 (de) 1994-04-15
DE69007471T2 (de) 1994-06-23
PT95959A (pt) 1991-09-13
HU9102436D0 (en) 1991-12-30
JP2574585B2 (ja) 1997-01-22
IL96390A0 (en) 1991-08-16
DE69033926D1 (de) 2002-04-11
EP0455789A1 (fr) 1991-11-13
WO1991007967A3 (fr) 1991-07-11
HK115095A (en) 1995-07-21

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