PT102145A - Derivados de piperazina acetamida, processo para a sua preparacao e composicoes farmaceuticas. - Google Patents

Derivados de piperazina acetamida, processo para a sua preparacao e composicoes farmaceuticas. Download PDF

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Publication number
PT102145A
PT102145A PT102145A PT10214598A PT102145A PT 102145 A PT102145 A PT 102145A PT 102145 A PT102145 A PT 102145A PT 10214598 A PT10214598 A PT 10214598A PT 102145 A PT102145 A PT 102145A
Authority
PT
Portugal
Prior art keywords
pharmaceutical compositions
peterazine
preparation
acetamide derivatives
compound
Prior art date
Application number
PT102145A
Other languages
English (en)
Other versions
PT102145B (pt
Inventor
Herman Van Bella
Willy Joannes Carolu Laethoven
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of PT102145A publication Critical patent/PT102145A/pt
Publication of PT102145B publication Critical patent/PT102145B/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166Streptokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Protection Of Pipes Against Damage, Friction, And Corrosion (AREA)
  • Dicing (AREA)
  • Branch Pipes, Bends, And The Like (AREA)
  • Golf Clubs (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Paper (AREA)
  • External Artificial Organs (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
PT102145A 1989-11-22 1998-04-20 Composicoes farmaceuticas a base de derivados de piperazina acetamida PT102145B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44014289A 1989-11-22 1989-11-22
SG118494A SG118494G (en) 1989-11-22 1994-08-20 Method of preventing or limiting reperfusion damage

Publications (2)

Publication Number Publication Date
PT102145A true PT102145A (pt) 1999-10-29
PT102145B PT102145B (pt) 2002-06-28

Family

ID=26664237

Family Applications (2)

Application Number Title Priority Date Filing Date
PT95959A PT95959B (pt) 1989-11-22 1990-11-22 Processo para a preparacao de derivados de n-aril-piperazinoalcanamida e de composicoes farmaceuticas que os contem
PT102145A PT102145B (pt) 1989-11-22 1998-04-20 Composicoes farmaceuticas a base de derivados de piperazina acetamida

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT95959A PT95959B (pt) 1989-11-22 1990-11-22 Processo para a preparacao de derivados de n-aril-piperazinoalcanamida e de composicoes farmaceuticas que os contem

Country Status (22)

Country Link
EP (2) EP0455789B1 (pt)
JP (1) JP2574585B2 (pt)
KR (1) KR0165686B1 (pt)
AT (2) ATE102831T1 (pt)
AU (1) AU632888B2 (pt)
CA (1) CA2044143C (pt)
CY (1) CY1869A (pt)
DE (2) DE69007471T2 (pt)
DK (2) DK0455789T3 (pt)
ES (2) ES2053208T3 (pt)
FI (1) FI109694B (pt)
HK (1) HK115095A (pt)
HU (1) HU215847B (pt)
IE (1) IE65121B1 (pt)
IL (1) IL96390A (pt)
NO (2) NO304519B1 (pt)
NZ (1) NZ236168A (pt)
PT (2) PT95959B (pt)
RU (1) RU2093156C1 (pt)
SG (1) SG118494G (pt)
WO (1) WO1991007967A2 (pt)
ZA (1) ZA909345B (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202266D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel piperazine carboxamides
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
KR100915263B1 (ko) 2001-05-18 2009-09-03 아스트라제네카 아베 4(페닐-피페라지닐-메틸)벤즈아미드 유도체 및 통증, 불안증 또는 위장관 장애 치료를 위한 이들의 용도
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
US20090018351A1 (en) * 2003-11-12 2009-01-15 Dr. Reddy's Laboratories, Inc. Preparation of escitalopram
MX2007001240A (es) 2004-08-02 2007-03-23 Astrazeneca Ab Derivados de diarilmetil-piperazina, preparaciones y usos de las mismas.
FR2946340B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux n-phenyl acetamie, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
KR101900124B1 (ko) 2014-06-25 2018-09-18 전남대학교산학협력단 전복 박리용 조성물
KR101644299B1 (ko) 2014-07-22 2016-08-02 주식회사 엔바이로젠 오미자 및 삼채 추출물을 유효성분으로 포함하는 전복 박리용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
NZ223847A (en) * 1987-04-01 1989-12-21 Janssen Pharmaceutica Nv Substituted piperazine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
NO982078L (no) 1991-08-26
HU9102436D0 (en) 1991-12-30
IE904209A1 (en) 1991-05-22
ATE213943T1 (de) 2002-03-15
DK0455789T3 (da) 1994-04-05
IE65121B1 (en) 1995-10-04
KR0165686B1 (ko) 1999-01-15
NO311701B1 (no) 2002-01-14
WO1991007967A2 (en) 1991-06-13
EP0455789A1 (en) 1991-11-13
PT102145B (pt) 2002-06-28
EP0577171A3 (en) 1994-06-29
NO912511L (no) 1991-08-26
PT95959B (pt) 1998-08-31
EP0577171B1 (en) 2002-03-06
CA2044143A1 (en) 1991-05-23
CY1869A (en) 1996-04-05
IL96390A0 (en) 1991-08-16
DE69033926T2 (de) 2002-10-24
DE69033926D1 (de) 2002-04-11
AU6876391A (en) 1991-06-26
EP0577171A2 (en) 1994-01-05
DE69007471D1 (de) 1994-04-21
NZ236168A (en) 1993-05-26
ES2173883T3 (es) 2002-11-01
SG118494G (en) 1994-11-25
ZA909345B (en) 1992-08-26
CA2044143C (en) 2002-11-19
NO982078D0 (no) 1998-05-07
WO1991007967A3 (en) 1991-07-11
EP0455789B1 (en) 1994-03-16
DE69007471T2 (de) 1994-06-23
HUT58709A (en) 1992-03-30
PT95959A (pt) 1991-09-13
FI913433A0 (fi) 1991-07-16
KR920700644A (ko) 1992-08-10
JP2574585B2 (ja) 1997-01-22
ES2053208T3 (es) 1994-07-16
NO912511D0 (no) 1991-06-26
ATE102831T1 (de) 1994-04-15
AU632888B2 (en) 1993-01-14
HK115095A (en) 1995-07-21
DK0577171T3 (da) 2002-06-03
HU215847B (hu) 1999-04-28
NO304519B1 (no) 1999-01-04
RU2093156C1 (ru) 1997-10-20
IL96390A (en) 1995-06-29
FI109694B (fi) 2002-09-30

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19980626

FG3A Patent granted, date of granting

Effective date: 20020322

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20081020