DE69007471D1 - Verfahren zur verhütung oder zur begrenzung einer reperfusionsschädigung. - Google Patents

Verfahren zur verhütung oder zur begrenzung einer reperfusionsschädigung.

Info

Publication number
DE69007471D1
DE69007471D1 DE90917677T DE69007471T DE69007471D1 DE 69007471 D1 DE69007471 D1 DE 69007471D1 DE 90917677 T DE90917677 T DE 90917677T DE 69007471 T DE69007471 T DE 69007471T DE 69007471 D1 DE69007471 D1 DE 69007471D1
Authority
DE
Germany
Prior art keywords
preventing
reperfusion damage
compound
limiting reperfusion
limiting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE90917677T
Other languages
English (en)
Other versions
DE69007471T2 (de
Inventor
Belle Herman Van
Laerhoven Willy Van
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Application granted granted Critical
Publication of DE69007471D1 publication Critical patent/DE69007471D1/de
Publication of DE69007471T2 publication Critical patent/DE69007471T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A61K38/166Streptokinase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/49Urokinase; Tissue plasminogen activator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Protection Of Pipes Against Damage, Friction, And Corrosion (AREA)
  • Dicing (AREA)
  • Branch Pipes, Bends, And The Like (AREA)
  • Golf Clubs (AREA)
  • Professional, Industrial, Or Sporting Protective Garments (AREA)
  • Suspension Of Electric Lines Or Cables (AREA)
  • Production Of Liquid Hydrocarbon Mixture For Refining Petroleum (AREA)
  • Paper (AREA)
  • External Artificial Organs (AREA)
DE69007471T 1989-11-22 1990-11-19 Verfahren zur verhütung oder zur begrenzung einer reperfusionsschädigung. Expired - Fee Related DE69007471T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44014289A 1989-11-22 1989-11-22
PCT/EP1990/001985 WO1991007967A2 (en) 1989-11-22 1990-11-19 Method of preventing or limiting reperfusion damage
SG118494A SG118494G (en) 1989-11-22 1994-08-20 Method of preventing or limiting reperfusion damage

Publications (2)

Publication Number Publication Date
DE69007471D1 true DE69007471D1 (de) 1994-04-21
DE69007471T2 DE69007471T2 (de) 1994-06-23

Family

ID=26664237

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69033926T Expired - Fee Related DE69033926T2 (de) 1989-11-22 1990-11-19 Verwendung von Piperazin-Acetamid-Derivaten gegen Reperfusionsschaden
DE69007471T Expired - Fee Related DE69007471T2 (de) 1989-11-22 1990-11-19 Verfahren zur verhütung oder zur begrenzung einer reperfusionsschädigung.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69033926T Expired - Fee Related DE69033926T2 (de) 1989-11-22 1990-11-19 Verwendung von Piperazin-Acetamid-Derivaten gegen Reperfusionsschaden

Country Status (22)

Country Link
EP (2) EP0455789B1 (de)
JP (1) JP2574585B2 (de)
KR (1) KR0165686B1 (de)
AT (2) ATE102831T1 (de)
AU (1) AU632888B2 (de)
CA (1) CA2044143C (de)
CY (1) CY1869A (de)
DE (2) DE69033926T2 (de)
DK (2) DK0455789T3 (de)
ES (2) ES2173883T3 (de)
FI (1) FI109694B (de)
HK (1) HK115095A (de)
HU (1) HU215847B (de)
IE (1) IE65121B1 (de)
IL (1) IL96390A (de)
NO (2) NO304519B1 (de)
NZ (1) NZ236168A (de)
PT (2) PT95959B (de)
RU (1) RU2093156C1 (de)
SG (1) SG118494G (de)
WO (1) WO1991007967A2 (de)
ZA (1) ZA909345B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9202266D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel piperazine carboxamides
SE9504661D0 (sv) 1995-12-22 1995-12-22 Astra Pharma Inc New compounds
US6683100B2 (en) 1999-01-19 2004-01-27 Novartis Ag Organic compounds
US6194181B1 (en) 1998-02-19 2001-02-27 Novartis Ag Fermentative preparation process for and crystal forms of cytostatics
SE9904674D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE9904673D0 (sv) 1999-12-20 1999-12-20 Astra Pharma Inc Novel compounds
SE0001209D0 (sv) 2000-04-04 2000-04-04 Astrazeneca Canada Inc Novel compounds
IL158631A0 (en) 2001-05-18 2004-05-12 Astrazeneca Ab 4-(phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders
SE0203300D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203302D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
SE0203303D0 (sv) 2002-11-07 2002-11-07 Astrazeneca Ab Novel Compounds
US20090018351A1 (en) * 2003-11-12 2009-01-15 Dr. Reddy's Laboratories, Inc. Preparation of escitalopram
DK1781631T3 (da) 2004-08-02 2012-05-14 Astrazeneca Ab Diarylmethylpiperazinderivater, præparater dermed og anvendelser deraf
FR2946340B1 (fr) 2009-06-05 2011-06-24 Galderma Res & Dev Nouveaux n-phenyl acetamie, inhibiteurs de l'enzyme soat-1, compositions pharmaceutiques et cosmetiques les contenant.
KR101900124B1 (ko) 2014-06-25 2018-09-18 전남대학교산학협력단 전복 박리용 조성물
KR101644299B1 (ko) 2014-07-22 2016-08-02 주식회사 엔바이로젠 오미자 및 삼채 추출물을 유효성분으로 포함하는 전복 박리용 조성물

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766125A (en) * 1981-06-23 1988-08-23 Janssen Pharmaceutica N.V. N-aryl-piperazinealkanamides useful for protecting hearts from myocardial injury caused by ischaemia, anoxia or hypoxia
NZ223847A (en) * 1987-04-01 1989-12-21 Janssen Pharmaceutica Nv Substituted piperazine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
SG118494G (en) 1994-11-25
AU632888B2 (en) 1993-01-14
FI109694B (fi) 2002-09-30
KR0165686B1 (ko) 1999-01-15
DK0455789T3 (da) 1994-04-05
PT95959A (pt) 1991-09-13
DE69007471T2 (de) 1994-06-23
KR920700644A (ko) 1992-08-10
ZA909345B (en) 1992-08-26
AU6876391A (en) 1991-06-26
NO304519B1 (no) 1999-01-04
EP0577171A3 (en) 1994-06-29
CY1869A (en) 1996-04-05
HK115095A (en) 1995-07-21
NO912511D0 (no) 1991-06-26
EP0455789A1 (de) 1991-11-13
ATE213943T1 (de) 2002-03-15
HU9102436D0 (en) 1991-12-30
FI913433A0 (fi) 1991-07-16
IE65121B1 (en) 1995-10-04
HUT58709A (en) 1992-03-30
IE904209A1 (en) 1991-05-22
JP2574585B2 (ja) 1997-01-22
HU215847B (hu) 1999-04-28
DE69033926D1 (de) 2002-04-11
PT102145A (pt) 1999-10-29
RU2093156C1 (ru) 1997-10-20
WO1991007967A2 (en) 1991-06-13
IL96390A (en) 1995-06-29
NO982078L (no) 1991-08-26
ES2053208T3 (es) 1994-07-16
PT95959B (pt) 1998-08-31
CA2044143C (en) 2002-11-19
NO311701B1 (no) 2002-01-14
DE69033926T2 (de) 2002-10-24
ES2173883T3 (es) 2002-11-01
EP0577171B1 (de) 2002-03-06
IL96390A0 (en) 1991-08-16
PT102145B (pt) 2002-06-28
ATE102831T1 (de) 1994-04-15
EP0577171A2 (de) 1994-01-05
NO982078D0 (no) 1998-05-07
DK0577171T3 (da) 2002-06-03
NO912511L (no) 1991-08-26
NZ236168A (en) 1993-05-26
WO1991007967A3 (en) 1991-07-11
CA2044143A1 (en) 1991-05-23
EP0455789B1 (de) 1994-03-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee