SG112059A1 - Analytical sandwich test for determining nt-probnp - Google Patents

Analytical sandwich test for determining nt-probnp

Info

Publication number
SG112059A1
SG112059A1 SG200406770A SG200406770A SG112059A1 SG 112059 A1 SG112059 A1 SG 112059A1 SG 200406770 A SG200406770 A SG 200406770A SG 200406770 A SG200406770 A SG 200406770A SG 112059 A1 SG112059 A1 SG 112059A1
Authority
SG
Singapore
Prior art keywords
probnp
antibodies
sandwich test
determining
analytical
Prior art date
Application number
SG200406770A
Other languages
English (en)
Inventor
Juergen Spinke Dr
Alfons Nichtl Dr
Volker Klemt Dr
Klaus Hallermayer Dr
Michael Grol Dr
Borgya Anneliese
Andreas Gallusser Dr
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SG112059A1 publication Critical patent/SG112059A1/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • G01N33/54386Analytical elements
    • G01N33/54387Immunochromatographic test strips
    • G01N33/54388Immunochromatographic test strips based on lateral flow
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Brain natriuretic peptide [BNP, proBNP]; Cardionatrin; Cardiodilatin
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80Antihypertensive peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
SG200406770A 2003-11-28 2004-11-24 Analytical sandwich test for determining nt-probnp SG112059A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10355731A DE10355731A1 (de) 2003-11-28 2003-11-28 Analytischer Sandwichtest zur Bestimmung von NT-proBNP

Publications (1)

Publication Number Publication Date
SG112059A1 true SG112059A1 (en) 2005-06-29

Family

ID=34442338

Family Applications (1)

Application Number Title Priority Date Filing Date
SG200406770A SG112059A1 (en) 2003-11-28 2004-11-24 Analytical sandwich test for determining nt-probnp

Country Status (14)

Country Link
US (2) US7507550B2 (fr)
EP (1) EP1536232B1 (fr)
JP (1) JP4236629B2 (fr)
KR (1) KR100620297B1 (fr)
CN (1) CN1316248C (fr)
AT (1) ATE487946T1 (fr)
AU (1) AU2004231236B2 (fr)
BR (1) BRPI0405215B8 (fr)
CA (1) CA2488483C (fr)
DE (2) DE10355731A1 (fr)
ES (1) ES2355556T3 (fr)
HK (1) HK1078647A1 (fr)
MX (1) MXPA04011672A (fr)
SG (1) SG112059A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2843396B1 (fr) * 2002-08-07 2005-04-15 Bio Rad Pasteur Anticorps specifiques pour le diagnostic de l'insuffisance cardiaque
DE10355731A1 (de) * 2003-11-28 2005-06-30 Roche Diagnostics Gmbh Analytischer Sandwichtest zur Bestimmung von NT-proBNP
ATE425458T1 (de) * 2006-01-14 2009-03-15 Hoffmann La Roche Immunologisches testelement mit verbesserter kontrollzone
EP1970709B1 (fr) * 2007-03-06 2013-07-10 Roche Diagnostics GmbH Utilisation de peptides de type BNP pour la prédiction de besoins de dialyse
CN101896816B (zh) * 2007-06-22 2014-08-20 B.R.A.H.M.S有限公司 用于检测分析物的方法
CN101230101B (zh) * 2008-01-25 2012-03-28 中国人民解放军第三军医大学 一种用作NT-proBNP免疫诊断试剂标准品的重组蛋白及制备方法与应用
US9482677B2 (en) 2008-02-27 2016-11-01 Scios Inc. Method, composition and device for sampling natriuretic peptides in a biological fluid
US20090286329A1 (en) * 2008-05-19 2009-11-19 Abbott Laboratoires Isolated human autoantibodies to natriuretic peptides and methods and kits for detecting human autoantibodies to natriuretic peptides
WO2012028697A1 (fr) 2010-09-01 2012-03-08 Eth Zürich, Institute Of Molecular Biology And Biophysics Système de purification par affinité sur la base d'une complémentation de brin de donneur
EP2594940A1 (fr) * 2011-11-16 2013-05-22 Koninklijke Philips Electronics N.V. Répulsion de particules pour améliorer le contact de surface dans des dosages immunologiques à particules magnétiques
CN102692512A (zh) * 2012-06-26 2012-09-26 南京基蛋生物科技有限公司 NT-proBNP双抗夹心快速检测试剂盒
CN102879589A (zh) * 2012-09-26 2013-01-16 中国人民解放军总医院 一种能稳定保存的人NT-proBNP制剂及其制备方法
WO2014159197A1 (fr) * 2013-03-14 2014-10-02 Instrumentation Laboratory Company Séparation de plasma du sang en utilisant un dispositif de filtration et ses procédés
CN105092832B (zh) * 2015-08-28 2016-11-30 宁波瑞源生物科技有限公司 一种NT-proBNP荧光免疫试剂及其制备方法
US10436773B2 (en) 2016-01-18 2019-10-08 Jana Care, Inc. Mobile device based multi-analyte testing analyzer for use in medical diagnostic monitoring and screening
CN105699458A (zh) * 2016-02-03 2016-06-22 洪国粦 用于NT-proBNP检测的新型免疫传感器及其制备方法
CN106771168A (zh) * 2016-12-30 2017-05-31 武汉纽康度生物科技股份有限公司 荧光免疫层析检测卡及其制备方法和应用
CN107478848B (zh) * 2017-08-23 2019-04-16 广州瑞博奥生物科技有限公司 定量检测人NT-proBNP的试剂盒及其制备方法
JP7527960B2 (ja) * 2017-12-15 2024-08-05 ジャナ ケア インコーポレイテッド 病状をモニターするためにペプチド濃度を測定する生体医療用測定装置、システム、及び方法
US11446009B2 (en) 2018-12-11 2022-09-20 Eko.Ai Pte. Ltd. Clinical workflow to diagnose heart disease based on cardiac biomarker measurements and AI recognition of 2D and doppler modality echocardiogram images
US11931207B2 (en) 2018-12-11 2024-03-19 Eko.Ai Pte. Ltd. Artificial intelligence (AI) recognition of echocardiogram images to enhance a mobile ultrasound device
US12001939B2 (en) 2018-12-11 2024-06-04 Eko.Ai Pte. Ltd. Artificial intelligence (AI)-based guidance for an ultrasound device to improve capture of echo image views
CN112707964B (zh) * 2019-10-25 2022-11-08 东莞市朋志生物科技有限公司 一种抗n末端脑钠肽前体的重组抗体
US11536732B2 (en) 2020-03-13 2022-12-27 Jana Care, Inc. Devices, systems, and methods for measuring biomarkers in biological fluids
JP7352503B2 (ja) * 2020-03-26 2023-09-28 三洋化成工業株式会社 磁性粒子、免疫測定用試薬、免疫測定用キット及び免疫測定方法
CN111781385B (zh) * 2020-08-19 2023-07-18 武汉生之源生物科技股份有限公司 一种NT-proBNP检测试剂盒及其制备方法
CN112986586A (zh) * 2021-02-20 2021-06-18 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
CN112964885B (zh) * 2021-02-20 2022-11-11 广东菲鹏生物有限公司 一种氨基末端脑尿钠肽检测方法和试剂盒
CN113580583B (zh) * 2021-08-04 2023-06-02 江苏毕辉建设工程有限公司 一种拼接整齐的房建水电暖施工用管道拼接装置

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5073484A (en) 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
DE3445816C1 (de) 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
CA1303983C (fr) 1987-03-27 1992-06-23 Robert W. Rosenstein Essai en phase solide
EP0560411B1 (fr) 1987-04-27 2000-07-26 Unilever N.V. Essais de liaisons spécifiques
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5141850A (en) 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
US5458852A (en) 1992-05-21 1995-10-17 Biosite Diagnostics, Inc. Diagnostic devices for the controlled movement of reagents without membranes
GB9211686D0 (en) 1992-06-03 1992-07-15 Medisinsk Innovation A S Chemical compounds
US5485852A (en) * 1994-12-12 1996-01-23 Johnson; Lanny L. Pain tolerance testing device
WO1997006439A1 (fr) 1995-08-09 1997-02-20 Quidel Corporation Lame d'epreuve et methode d'analyse en flux lateral en une seule etape
US6833275B1 (en) 1997-07-22 2004-12-21 Roche Diagnostics Gmbh Gold conjugates containing detergent
US6117644A (en) 1998-06-04 2000-09-12 Ottawa Heart Institute Research Corporation Predicting and detecting cardiac allograft rejection
GB9827348D0 (en) * 1998-12-12 1999-02-03 Univ Leicester Natriuretic peptide
CN101046478B (zh) * 1999-01-29 2013-04-03 罗赫诊断器材股份有限公司 鉴定样品中的n-末端前bnp的方法
US6136963A (en) * 1999-07-27 2000-10-24 Heska Corporation Parasitic helminth DiAg2 nucleic acid molecules, and uses thereof
JP2002272458A (ja) * 2000-09-29 2002-09-24 Shionogi & Co Ltd イヌbnpに対する特異抗体を用いたサンドイッチ測定方法
US7632647B2 (en) 2001-04-13 2009-12-15 Biosite Incorporated Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes
US6461828B1 (en) 2001-09-04 2002-10-08 Syn X Pharma Conjunctive analysis of biological marker expression for diagnosing organ failure
AUPS169202A0 (en) * 2002-04-11 2002-05-16 Goetze, Jens Peter Neuropeptide assay
JP4610025B2 (ja) * 2002-11-18 2011-01-12 シン.クス ファーマ、インコーポレイテッド NT−proBNP検出用ポリクローナル・モノクローナル・エライサ検定法
US7109023B2 (en) * 2002-11-18 2006-09-19 Princeton Biomeditech Corporation Immunossay device for diagnosing congestive heart failure and predicting mortality in congestive heart failure patients
US20040096919A1 (en) * 2002-11-18 2004-05-20 Michelle Davey Polyclonal-monoclonal ELISA assay for detecting N-terminus proBNP
DK1625163T3 (da) * 2003-05-12 2011-12-05 Hoffmann La Roche Fremgangsmåde til at påvise proBNP med en monoklonal antistofbinding til aminosyrerne 38-43
DE10355731A1 (de) * 2003-11-28 2005-06-30 Roche Diagnostics Gmbh Analytischer Sandwichtest zur Bestimmung von NT-proBNP

Also Published As

Publication number Publication date
CN1316248C (zh) 2007-05-16
US20050118662A1 (en) 2005-06-02
CA2488483A1 (fr) 2005-05-28
ES2355556T3 (es) 2011-03-28
JP2005181304A (ja) 2005-07-07
EP1536232B1 (fr) 2010-11-10
US20090123947A1 (en) 2009-05-14
EP1536232A3 (fr) 2006-08-09
KR100620297B1 (ko) 2006-09-12
HK1078647A1 (en) 2006-03-17
DE502004011867D1 (de) 2010-12-23
BRPI0405215B8 (pt) 2021-07-27
JP4236629B2 (ja) 2009-03-11
MXPA04011672A (es) 2005-06-01
AU2004231236B2 (en) 2006-10-19
AU2004231236A1 (en) 2005-06-16
BRPI0405215B1 (pt) 2016-08-02
CA2488483C (fr) 2011-09-06
BRPI0405215A (pt) 2005-07-19
ATE487946T1 (de) 2010-11-15
DE10355731A1 (de) 2005-06-30
KR20050052354A (ko) 2005-06-02
US9140709B2 (en) 2015-09-22
EP1536232A2 (fr) 2005-06-01
CN1641352A (zh) 2005-07-20
US7507550B2 (en) 2009-03-24

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