SG11202102841WA - Magnetic separation - Google Patents

Magnetic separation

Info

Publication number
SG11202102841WA
SG11202102841WA SG11202102841WA SG11202102841WA SG11202102841WA SG 11202102841W A SG11202102841W A SG 11202102841WA SG 11202102841W A SG11202102841W A SG 11202102841WA SG 11202102841W A SG11202102841W A SG 11202102841WA SG 11202102841W A SG11202102841W A SG 11202102841WA
Authority
SG
Singapore
Prior art keywords
magnetic separation
separation
magnetic
Prior art date
Application number
SG11202102841WA
Other languages
English (en)
Inventor
Timothy Smith
Nuala Trainor
Kevin Middleton
Alexis Pietak
Original Assignee
Octane Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Octane Biotech Inc filed Critical Octane Biotech Inc
Publication of SG11202102841WA publication Critical patent/SG11202102841WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04Cell isolation or sorting
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/005Pretreatment specially adapted for magnetic separation
    • B03C1/01Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0332Component parts; Auxiliary operations characterised by the magnetic circuit using permanent magnets
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/025High gradient magnetic separators
    • B03C1/031Component parts; Auxiliary operations
    • B03C1/033Component parts; Auxiliary operations characterised by the magnetic circuit
    • B03C1/0335Component parts; Auxiliary operations characterised by the magnetic circuit using coils
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00Magnetic separation
    • B03C1/02Magnetic separation acting directly on the substance being separated
    • B03C1/28Magnetic plugs and dipsticks
    • B03C1/288Magnetic plugs and dipsticks disposed at the outer circumference of a recipient
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081Purging biological preparations of unwanted cells
    • C12N5/0087Purging against subsets of blood cells, e.g. purging alloreactive T cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0636T lymphocytes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326Magnetic particles
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/18Magnetic separation whereby the particles are suspended in a liquid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B03SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03CMAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C2201/00Details of magnetic or electrostatic separation
    • B03C2201/26Details of magnetic or electrostatic separation for use in medical or biological applications
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2509/00Methods for the dissociation of cells, e.g. specific use of enzymes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Sustainable Development (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Computer Hardware Design (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SG11202102841WA 2018-09-28 2019-09-25 Magnetic separation SG11202102841WA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862738331P 2018-09-28 2018-09-28
US201962897041P 2019-09-06 2019-09-06
PCT/CA2019/051371 WO2020061696A1 (fr) 2018-09-28 2019-09-25 Séparation magnétique

Publications (1)

Publication Number Publication Date
SG11202102841WA true SG11202102841WA (en) 2021-04-29

Family

ID=69949234

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202102841WA SG11202102841WA (en) 2018-09-28 2019-09-25 Magnetic separation

Country Status (9)

Country Link
US (1) US20210403856A1 (fr)
EP (1) EP3856922A4 (fr)
JP (2) JP7396777B2 (fr)
KR (1) KR20210086630A (fr)
CN (1) CN112752847A (fr)
CA (1) CA3113125A1 (fr)
IL (1) IL281737A (fr)
SG (1) SG11202102841WA (fr)
WO (1) WO2020061696A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3338895B1 (fr) 2007-12-07 2022-08-10 Miltenyi Biotec B.V. & Co. KG Systèmes et procédés de traitement d'échantillons
CN111621416A (zh) * 2020-05-14 2020-09-04 南京大学 一种基于移动磁网的生物磁性分离方法
US20220050105A1 (en) * 2020-08-12 2022-02-17 Boston Molecules, Inc. Method and apparatus for detecting viruses in biological samples
JP2023029014A (ja) * 2021-08-20 2023-03-03 株式会社日立ハイテク 試料分析装置
CN113721015B (zh) * 2021-09-08 2023-03-21 中国农业大学 微生物自动化检测装置、系统及方法
WO2024150586A1 (fr) * 2023-01-12 2024-07-18 パナソニックIpマネジメント株式会社 Récipient de culture cellulaire, dispositif de culture cellulaire et récipient de culture
CN116371596B (zh) * 2023-05-26 2023-08-18 北京华科泰生物技术股份有限公司 一种集成式磁分离设备

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1578A (en) * 2001-02-16 2006-02-22 Ausmetec Pty Ltd An apparatus and process for inducing magnetism.
US7166443B2 (en) * 2001-10-11 2007-01-23 Aviva Biosciences Corporation Methods, compositions, and automated systems for separating rare cells from fluid samples
GB2425498A (en) * 2005-04-25 2006-11-01 Dynal Biotech Asa A magnetic separation device
JP2007203244A (ja) * 2006-02-03 2007-08-16 Michio Shibatani 破砕攪拌方法
JP2007237008A (ja) * 2006-03-04 2007-09-20 Michio Shibatani 破砕方法及び破砕装置
KR101431778B1 (ko) * 2007-02-09 2014-08-20 어드밴스드 리퀴드 로직, 아이엔씨. 자성 비즈를 이용하는 액적 작동기 장치 및 방법
US8071395B2 (en) 2007-12-12 2011-12-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and apparatus for magnetic separation of cells
US8316861B2 (en) * 2008-10-21 2012-11-27 The Board Of Trustees Of The Leland Stanford Junior University System and method for guiding a medical instrument with magnetic force control
AU2010239154A1 (en) * 2009-04-22 2011-11-10 Clinical Genomics Pty. Ltd. Method and apparatus for isolating a target bioentity from a biological sample
US8790916B2 (en) * 2009-05-14 2014-07-29 Genestream, Inc. Microfluidic method and system for isolating particles from biological fluid
EP2752668A3 (fr) * 2010-07-23 2014-10-15 Beckman Coulter, Inc. Système ou procédé comprenant des unités analytiques
WO2013130875A1 (fr) * 2012-02-29 2013-09-06 President And Fellows Of Harvard College Test rapide de sensibilité aux antibiotiques
US9752968B2 (en) * 2012-12-21 2017-09-05 Luminex Corporation Rotating shielded magnetic actuator
CN105792926B (zh) * 2013-09-09 2018-06-22 微球实验公司 用于磁性分离的新工艺和系统
CN205570357U (zh) * 2016-01-04 2016-09-14 上海医脉赛科技有限公司 一种提取及检测生物样本的装置
CN105586258B (zh) * 2016-03-14 2018-08-17 佛山市汇广健医疗科技有限公司 磁性吸附转移棒

Also Published As

Publication number Publication date
JP2024028773A (ja) 2024-03-05
JP2022502638A (ja) 2022-01-11
IL281737A (en) 2021-05-31
JP7396777B2 (ja) 2023-12-12
EP3856922A1 (fr) 2021-08-04
CN112752847A (zh) 2021-05-04
WO2020061696A1 (fr) 2020-04-02
CA3113125A1 (fr) 2020-04-02
EP3856922A4 (fr) 2022-07-06
US20210403856A1 (en) 2021-12-30
KR20210086630A (ko) 2021-07-08

Similar Documents

Publication Publication Date Title
IL281737A (en) magnetic separation
IL280221A (en) Magnetic particles
ZA201904882B (en) Magnetic separator
GB2600884B (en) Magnet configurations
SG11202012126UA (en) Magnetic marker
EP3634634A4 (fr) Separation magnetique trans-interfaciale
GB201816400D0 (en) An improved machine for the magnetic separation
PL3900837T3 (pl) Filtr magnetyczny
PL3594746T3 (pl) Uchwyt magnetyczny
GB2592486B (en) Optically-induced auto-encapsulation
SG11202102967PA (en) Magnetic levitation
ZA201903193B (en) Planar magnetic separator
GB201605181D0 (en) Magnetic filters
SG10201908736TA (en) Magnetic separator
GB2573440B (en) Magnetic filter
GB2573439B (en) Magnetic filter
GB201818311D0 (en) Magnetic opitimisation
EP4054768C0 (fr) Séparateur magnétique
GB201820438D0 (en) Magnetic field
GB2585529B (en) Magnetic filter
GB2575861B (en) Separator
GB2575422B (en) Magnetic apparatus
GB201819614D0 (en) Magnetic optimisation
GB201805142D0 (en) Separation method
GB201803858D0 (en) Magnetic hangers