US4269846A
(en)
|
1979-10-29 |
1981-05-26 |
Usv Pharmaceutical Corporation |
Heterocyclic compounds useful as anti-allergy agents
|
US5137876A
(en)
|
1990-10-12 |
1992-08-11 |
Merck & Co., Inc. |
Nucleoside antiviral and anti-inflammatory compounds and compositions and methods for using same
|
US5521184A
(en)
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
DE69942097D1
(de)
|
1998-08-11 |
2010-04-15 |
Novartis Ag |
Isochinoline derivate mit angiogenesis-hemmender wirkung
|
US6133031A
(en)
|
1999-08-19 |
2000-10-17 |
Isis Pharmaceuticals Inc. |
Antisense inhibition of focal adhesion kinase expression
|
GB9905075D0
(en)
|
1999-03-06 |
1999-04-28 |
Zeneca Ltd |
Chemical compounds
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
GB0011092D0
(en)
|
2000-05-08 |
2000-06-28 |
Black James Foundation |
Gastrin and cholecystokinin receptor ligands (III)
|
PT1294358E
(pt)
|
2000-06-28 |
2004-12-31 |
Smithkline Beecham Plc |
Processo de moagem por via humida
|
CA2466243A1
(en)
|
2001-09-19 |
2003-03-27 |
Aventis Pharma S.A. |
Indolizines as kinase protein inhibitors
|
IL161576A0
(en)
|
2001-10-26 |
2004-09-27 |
Aventis Pharma Inc |
Benzimidazoles and analogues and their use as protein kinases inhibitors
|
FR2831536A1
(fr)
|
2001-10-26 |
2003-05-02 |
Aventis Pharma Sa |
Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr
|
KR20090087139A
(ko)
|
2001-10-30 |
2009-08-14 |
노파르티스 아게 |
Flt3 수용체 티로신 키나아제 활성의 억제제로서의 스타우로스포린 유도체
|
DE10207843A1
(de)
|
2002-02-15 |
2003-09-04 |
Schering Ag |
Mikrolia-Inhibitoren zur Unterbrechung von Interleukin 12 und IFN-gamma vermittelten Immunreaktionen
|
TW200406374A
(en)
|
2002-05-29 |
2004-05-01 |
Novartis Ag |
Diaryl urea derivatives useful for the treatment of protein kinase dependent diseases
|
GB0215676D0
(en)
|
2002-07-05 |
2002-08-14 |
Novartis Ag |
Organic compounds
|
AR042052A1
(es)
|
2002-11-15 |
2005-06-08 |
Vertex Pharma |
Diaminotriazoles utiles como inhibidores de proteinquinasas
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
US7157460B2
(en)
|
2003-02-20 |
2007-01-02 |
Sugen Inc. |
Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
|
US7186832B2
(en)
|
2003-02-20 |
2007-03-06 |
Sugen Inc. |
Use of 8-amino-aryl-substituted imidazopyrazines as kinase inhibitors
|
WO2004078943A2
(en)
|
2003-03-04 |
2004-09-16 |
California Institute Of Technology |
Alternative heterocycles for dna recognition
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
RU2355687C2
(ru)
|
2003-08-01 |
2009-05-20 |
Дженелэбс Текнолоджиз, Инк |
Бициклические производные имидазола в качестве средства против вирусов семейства flaviviridae
|
PE20050952A1
(es)
|
2003-09-24 |
2005-12-19 |
Novartis Ag |
Derivados de isoquinolina como inhibidores de b-raf
|
WO2005118580A2
(en)
|
2004-05-12 |
2005-12-15 |
The Government Of The United States Of America As Represented By The Secretary, Department Of Health |
Tricyclic compounds as inhibitors of the hypoxic signaling pathway
|
MY144044A
(en)
|
2004-06-10 |
2011-07-29 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
KR20070085433A
(ko)
|
2004-11-24 |
2007-08-27 |
노파르티스 아게 |
Jak 저해제들과 bcr-abl, flt-3, fak 또는raf 키나제 저해제들 중 하나 이상의 조합물
|
ES2431050T3
(es)
|
2005-08-04 |
2013-11-22 |
Sirtris Pharmaceuticals, Inc. |
Benzotiazoles y tiazolopiridinas como moduladores de la sirtuína
|
CA2620223A1
(en)
*
|
2005-09-02 |
2007-03-08 |
Abbott Laboratories |
Novel imidazo based heterocycles
|
CN101472912A
(zh)
|
2006-06-22 |
2009-07-01 |
比奥维特罗姆上市公司 |
作为mnk激酶抑制剂的吡啶和吡嗪衍生物
|
EP2139474A2
(en)
|
2007-03-27 |
2010-01-06 |
Paratek Pharmaceuticals, Inc. |
Transcription factor modulating compounds and methods of use thereof
|
DE102007035333A1
(de)
|
2007-07-27 |
2009-01-29 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Neue substituierte Arylsulfonylglycine, deren Herstellung und deren Verwendung als Arzneimittel
|
GB0716292D0
(en)
|
2007-08-21 |
2007-09-26 |
Biofocus Dpi Ltd |
Imidazopyrazine compounds
|
BRPI0820544A2
(pt)
|
2007-11-16 |
2015-06-16 |
Incyte Corp |
4-pirazolil-n-arilpirimidin-2-aminas e pirazolil-n-heteroarilpirimidin-2-aminas como inibidores de janus cinase
|
CA2709883A1
(en)
|
2007-12-19 |
2009-06-25 |
The Scripps Research Institute |
Benzimidazoles and analogs as rho kinase inhibitors
|
JP5795714B2
(ja)
|
2008-01-15 |
2015-10-14 |
シガ・テクノロジーズ・インコーポレーテッド |
アレナウイルス感染症の治療のための抗ウイルス薬
|
US8329697B2
(en)
|
2008-02-26 |
2012-12-11 |
Merck Sharp & Dohme Corp. |
Imidizo[1,2-A]pyrazines useful as AHCY hydrolase inhibitors
|
KR20120108042A
(ko)
|
2008-03-11 |
2012-10-04 |
인사이트 코포레이션 |
Jak 억제제로서의 아제티딘 및 시클로부탄 유도체
|
WO2009133127A1
(en)
|
2008-04-30 |
2009-11-05 |
Merck Serono S.A. |
Fused bicyclic compounds and use thereof as pi3k inhibitors
|
CA2763536C
(en)
|
2008-05-30 |
2017-05-09 |
Marvin J. Miller |
Anti-bacterial agents from benzo[d]heterocyclic scaffolds for prevention and treatment of multidrug resistant bacteria
|
WO2010051245A1
(en)
|
2008-11-03 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Benzimidazole and aza-benzimidazole carboxamides
|
TW201028399A
(en)
|
2008-11-27 |
2010-08-01 |
Shionogi & Co |
Pyrimidine derivative and pyridine derivative both having pi3k inhibitory activity
|
GB0822981D0
(en)
|
2008-12-17 |
2009-01-21 |
Summit Corp Plc |
Compounds for treatment of duchenne muscular dystrophy
|
WO2010135014A1
(en)
|
2009-02-27 |
2010-11-25 |
Vertex Pharmaceuticals Incorporated |
Tri-cyclic pyrazolopyridine kinase inhibitors
|
US8716303B2
(en)
|
2009-05-22 |
2014-05-06 |
Incyte Corporation |
N-(hetero)aryl-pyrrolidine derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines and pyrrol-3-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
|
AU2010273816B2
(en)
|
2009-06-29 |
2015-07-09 |
Incyte Holdings Corporation |
Pyrimidinones as PI3K inhibitors
|
US9249145B2
(en)
|
2009-09-01 |
2016-02-02 |
Incyte Holdings Corporation |
Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
|
WO2011075643A1
(en)
|
2009-12-18 |
2011-06-23 |
Incyte Corporation |
Substituted heteroaryl fused derivatives as pi3k inhibitors
|
WO2011075630A1
(en)
|
2009-12-18 |
2011-06-23 |
Incyte Corporation |
Substituted fused aryl and heteroaryl derivatives as pi3k inhibitors
|
WO2011099832A2
(en)
|
2010-02-12 |
2011-08-18 |
Crystalgenomics, Inc. |
Novel benzimidazole compound, preparation method thereof and pharmaceutical composition comprising the same
|
AR080754A1
(es)
*
|
2010-03-09 |
2012-05-09 |
Janssen Pharmaceutica Nv |
Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
|
KR102354472B1
(ko)
|
2010-03-10 |
2022-01-21 |
인사이트 홀딩스 코포레이션 |
Jak1 저해제로서의 피페리딘4일 아제티딘 유도체
|
WO2011123609A1
(en)
|
2010-03-31 |
2011-10-06 |
Glaxo Group Limited |
Imidazolyl-imidazoles as kinase inhibitors
|
WO2011130342A1
(en)
|
2010-04-14 |
2011-10-20 |
Incyte Corporation |
FUSED DERIVATIVES AS ΡI3Κδ INHIBITORS
|
US8877707B2
(en)
|
2010-05-24 |
2014-11-04 |
Presidio Pharmaceuticals, Inc. |
Inhibitors of HCV NS5A
|
WO2011149874A2
(en)
|
2010-05-26 |
2011-12-01 |
Schering Corporation |
N-phenyl imidazole carboxamide inhibitors of 3-phosphoinositide-dependent protein kinase-1
|
US9062055B2
(en)
|
2010-06-21 |
2015-06-23 |
Incyte Corporation |
Fused pyrrole derivatives as PI3K inhibitors
|
TW201307309A
(zh)
|
2010-10-13 |
2013-02-16 |
Millennium Pharm Inc |
雜芳基化合物及其用途
|
WO2012068450A1
(en)
|
2010-11-19 |
2012-05-24 |
Incyte Corporation |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as jak inhibitors
|
JP5917544B2
(ja)
|
2010-11-19 |
2016-05-18 |
インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation |
Jak阻害剤としての複素環置換ピロロピリジンおよびピロロピリミジン
|
BR112013013417A2
(pt)
|
2010-11-30 |
2019-09-24 |
Takeda Pharmaceuticals Co |
composto, medicamento, métodos para inibir a acetil-coa carboxilase em um mamífero, e de profilaxia ou tratamento da obesidade ou diabete em um mamífero, e, uso de um composto ou sal
|
EP2655374B1
(en)
|
2010-12-20 |
2019-10-23 |
Incyte Holdings Corporation |
N-(1-(substituted-phenyl)ethyl)-9h-purin-6-amines as pi3k inhibitors
|
WO2012125629A1
(en)
|
2011-03-14 |
2012-09-20 |
Incyte Corporation |
Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
|
US8673905B2
(en)
|
2011-03-17 |
2014-03-18 |
Hoffmann-La Roche Inc. |
Imidazo pyrazines
|
US9126948B2
(en)
|
2011-03-25 |
2015-09-08 |
Incyte Holdings Corporation |
Pyrimidine-4,6-diamine derivatives as PI3K inhibitors
|
US9029389B2
(en)
|
2011-04-21 |
2015-05-12 |
Institut Pasteur Korea |
Anti-inflammation compounds
|
EP2718279B1
(en)
|
2011-06-09 |
2016-08-10 |
Rhizen Pharmaceuticals SA |
Novel compounds as modulators of gpr-119
|
JP5876146B2
(ja)
|
2011-06-20 |
2016-03-02 |
インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation |
Jak阻害剤としてのアゼチジニルフェニル、ピリジル、またはピラジニルカルボキサミド誘導体
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為jak抑制劑之環己基氮雜環丁烷衍生物
|
AR087760A1
(es)
|
2011-09-02 |
2014-04-16 |
Incyte Corp |
Heterociclilaminas como inhibidores de pi3k
|
CN104066735B
(zh)
*
|
2012-01-10 |
2016-08-31 |
拜耳知识产权有限责任公司 |
作为akt激酶抑制剂的取代的咪唑并吡嗪
|
US9212169B2
(en)
|
2012-03-01 |
2015-12-15 |
Hyogo College Of Medicine |
Benzimidazole derivative and use thereof
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
AR091079A1
(es)
|
2012-05-18 |
2014-12-30 |
Incyte Corp |
Derivados de pirrolopirimidina y pirrolopiridina sustituida con piperidinilciclobutilo como inhibidores de jak
|
EP2857396B1
(en)
|
2012-05-31 |
2018-11-21 |
Sumitomo Chemical Co., Ltd |
Fused heterocyclic compounds for pest control
|
EA028722B1
(ru)
|
2012-07-13 |
2017-12-29 |
Юсб Байофарма Спрл |
Производные имидазопиридина в качестве модуляторов активности tnf
|
SG10201703533VA
(en)
|
2012-11-01 |
2017-06-29 |
Incyte Corp |
Tricyclic fused thiophene derivatives as jak inhibitors
|
TWI736135B
(zh)
|
2013-03-01 |
2021-08-11 |
美商英塞特控股公司 |
吡唑并嘧啶衍生物治療PI3Kδ相關病症之用途
|
WO2014149207A2
(en)
|
2013-03-15 |
2014-09-25 |
Dow Agrosciences Llc |
Benzimidazole-based insecticidal compositions and related methods
|
US8999992B2
(en)
|
2013-03-15 |
2015-04-07 |
Vm Pharma Llc |
Crystalline forms of tryosine kinase inhibitors and their salts
|
EP2976077A4
(en)
|
2013-03-22 |
2016-11-30 |
Scripps Research Inst |
BENZIMIDAZOLES SUBSTITUTED AS MODULATORS OF A NOCICEPTIN RECEPTOR
|
US9394254B2
(en)
|
2013-05-08 |
2016-07-19 |
The University of Denver and Regis University |
Antibiotic and anti-parasitic agents that modulate class II fructose 1,6-bisphosphate aldolase
|
SI3527263T1
(sl)
|
2013-05-17 |
2021-05-31 |
Incyte Corporation |
Derivati bipirazola kot zaviralci JAK
|
AU2014291142B2
(en)
|
2013-07-17 |
2018-10-11 |
Otsuka Pharmaceutical Co., Ltd. |
Cyanotriazole compounds
|
WO2015051241A1
(en)
|
2013-10-04 |
2015-04-09 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
UA119767C2
(uk)
|
2014-04-08 |
2019-08-12 |
Інсайт Корпорейшн |
Лікування b-клітинних злоякісних новоутворень із застосуванням комбінації інгібіторів jak та pi3k
|
EP2930048A1
(en)
|
2014-04-10 |
2015-10-14 |
Johnson Controls Automotive Electronics SAS |
Head up display projecting visual information onto a screen
|
US10077277B2
(en)
|
2014-06-11 |
2018-09-18 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as PI3K inhibitors
|
ES2911292T3
(es)
|
2014-09-16 |
2022-05-18 |
Celgene Quanticel Res Inc |
Inhibidores de desmetilasas de histonas
|
ES2807785T3
(es)
|
2014-10-22 |
2021-02-24 |
Bristol Myers Squibb Co |
Compuestos de heteroarilamina bicíclicos como inhibidores de pi3k
|
MA40933A
(fr)
|
2014-11-11 |
2017-09-19 |
Piqur Therapeutics Ag |
Difluorométhyl-aminopyridines et difluorométhyl-aminopyrimidines
|
WO2016130501A1
(en)
|
2015-02-09 |
2016-08-18 |
Incyte Corporation |
Aza-heteroaryl compounds as pi3k-gamma inhibitors
|
US9968604B2
(en)
|
2015-04-16 |
2018-05-15 |
Chiesi Farmaceutici S.P.A. |
Chromene derivatives as phoshoinositide 3-kinases inhibitors
|
PL3371190T3
(pl)
|
2015-11-06 |
2022-11-07 |
Incyte Corporation |
Związki heterocykliczne jako inhibitory pi3k-gamma
|
ES2833955T3
(es)
|
2016-01-05 |
2021-06-16 |
Incyte Corp |
Piridinas sustituidas con pirazol/imidazol como inhibidores de PI3K-Gamma
|
WO2017223414A1
(en)
|
2016-06-24 |
2017-12-28 |
Incyte Corporation |
HETEROCYCLIC COMPOUNDS AS PI3K-γ INHIBITORS
|
EP3505171A4
(en)
|
2016-08-26 |
2020-08-26 |
Mitsubishi Tanabe Pharma Corporation |
BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND
|
WO2019079469A1
(en)
|
2017-10-18 |
2019-04-25 |
Incyte Corporation |
CONDENSED IMIDAZOLE DERIVATIVES SUBSTITUTED WITH HYDROXY TERTIARY GROUPS AS INHIBITORS OF PI3K-GAMMA
|