SG11202004914RA - Spray-dried mixture of human milk oligosacchrides - Google Patents

Spray-dried mixture of human milk oligosacchrides

Info

Publication number
SG11202004914RA
SG11202004914RA SG11202004914RA SG11202004914RA SG11202004914RA SG 11202004914R A SG11202004914R A SG 11202004914RA SG 11202004914R A SG11202004914R A SG 11202004914RA SG 11202004914R A SG11202004914R A SG 11202004914RA SG 11202004914R A SG11202004914R A SG 11202004914RA
Authority
SG
Singapore
Prior art keywords
oligosacchrides
spray
human milk
dried mixture
dried
Prior art date
Application number
SG11202004914RA
Other languages
English (en)
Inventor
Stefan Jennewein
Original Assignee
Jennewein Biotechnologie Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP17206223.4A external-priority patent/EP3494806A1/fr
Priority claimed from EP17206159.0A external-priority patent/EP3494805A1/fr
Priority claimed from EP17206124.4A external-priority patent/EP3494804A1/fr
Priority claimed from EP17206414.9A external-priority patent/EP3494807A1/fr
Priority claimed from EP18155669.7A external-priority patent/EP3524067A1/fr
Application filed by Jennewein Biotechnologie Gmbh filed Critical Jennewein Biotechnologie Gmbh
Publication of SG11202004914RA publication Critical patent/SG11202004914RA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
    • A23C9/00—Milk preparations; Milk powder or milk powder preparations
    • A23C9/20—Dietetic milk products not covered by groups A23C9/12 - A23C9/18
    • A23C9/206—Colostrum; Human milk
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/065—Microorganisms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/40—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by drying or kilning; Subsequent reconstitution
    • A23L3/46—Spray-drying
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/18—Peptides; Protein hydrolysates
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
    • A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L5/00—Preparation or treatment of foods or foodstuffs, in general; Food or foodstuffs obtained thereby; Materials therefor
    • A23L5/20—Removal of unwanted matter, e.g. deodorisation or detoxification
    • A23L5/27—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption
    • A23L5/273—Removal of unwanted matter, e.g. deodorisation or detoxification by chemical treatment, by adsorption or by absorption using adsorption or absorption agents, resins, synthetic polymers, or ion exchangers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P10/00—Shaping or working of foodstuffs characterised by the products
    • A23P10/40—Shaping or working of foodstuffs characterised by the products free-flowing powder or instant powder, i.e. powder which is reconstituted rapidly when liquid is added
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23P—SHAPING OR WORKING OF FOODSTUFFS, NOT FULLY COVERED BY A SINGLE OTHER SUBCLASS
    • A23P30/00—Shaping or working of foodstuffs characterised by the process or apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/02—Reverse osmosis; Hyperfiltration ; Nanofiltration
    • B01D61/027—Nanofiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/42—Electrodialysis; Electro-osmosis ; Electro-ultrafiltration; Membrane capacitive deionization
    • B01D61/422—Electrodialysis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/58—Multistep processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/0018—Evaporation of components of the mixture to be separated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D9/005—Selection of auxiliary, e.g. for control of crystallisation nuclei, of crystal growth, of adherence to walls; Arrangements for introduction thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/10—Drying, dehydrating
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2300/00—Processes
    • A23V2300/38—Multiple-step
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D9/00—Crystallisation
    • B01D2009/0086—Processes or apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/02—Specific process operations before starting the membrane separation process
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2623—Ion-Exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2626—Absorption or adsorption

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Water Supply & Treatment (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pediatric Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Nanotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Dairy Products (AREA)
SG11202004914RA 2017-12-08 2018-12-07 Spray-dried mixture of human milk oligosacchrides SG11202004914RA (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
EP17206223.4A EP3494806A1 (fr) 2017-12-08 2017-12-08 Lacto-n-fucopentaose séché par pulvérisation
EP17206159.0A EP3494805A1 (fr) 2017-12-08 2017-12-08 Tétrasaccharide séché en pulvérisation
EP17206124.4A EP3494804A1 (fr) 2017-12-08 2017-12-08 3-fucosyllactose séché en pulvérisation
EP17206414.9A EP3494807A1 (fr) 2017-12-11 2017-12-11 Sialyllactose séché par pulvérisation
EP18155669.7A EP3524067A1 (fr) 2018-02-08 2018-02-08 Mélange séchant par pulvérisation d'oligosaccharides de lait humain
PCT/EP2018/083968 WO2019110800A1 (fr) 2017-12-08 2018-12-07 Mélange séché par atomisation à base d'oligosaccharides du lait maternel

Publications (1)

Publication Number Publication Date
SG11202004914RA true SG11202004914RA (en) 2020-06-29

Family

ID=64564901

Family Applications (5)

Application Number Title Priority Date Filing Date
SG11202004914RA SG11202004914RA (en) 2017-12-08 2018-12-07 Spray-dried mixture of human milk oligosacchrides
SG11202004650SA SG11202004650SA (en) 2017-12-08 2018-12-07 Spray-dried tetrasaccharides
SG11202004414PA SG11202004414PA (en) 2017-12-08 2018-12-07 Spray-dried 3-fucosyllactose
SG11202004655PA SG11202004655PA (en) 2017-12-08 2018-12-07 Spray-dried lacto-n-fucopentaose
SG11202004659QA SG11202004659QA (en) 2017-12-08 2018-12-07 Spray-dried sialyllactose

Family Applications After (4)

Application Number Title Priority Date Filing Date
SG11202004650SA SG11202004650SA (en) 2017-12-08 2018-12-07 Spray-dried tetrasaccharides
SG11202004414PA SG11202004414PA (en) 2017-12-08 2018-12-07 Spray-dried 3-fucosyllactose
SG11202004655PA SG11202004655PA (en) 2017-12-08 2018-12-07 Spray-dried lacto-n-fucopentaose
SG11202004659QA SG11202004659QA (en) 2017-12-08 2018-12-07 Spray-dried sialyllactose

Country Status (16)

Country Link
US (5) US20210161192A1 (fr)
EP (5) EP3720299A1 (fr)
JP (8) JP2021505170A (fr)
KR (5) KR20200096770A (fr)
CN (5) CN111447843A (fr)
AT (1) AT17129U1 (fr)
AU (5) AU2018380960A1 (fr)
BR (5) BR112020011300A2 (fr)
CZ (1) CZ35153U1 (fr)
DE (1) DE202018006272U1 (fr)
DK (2) DK201900079Y4 (fr)
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Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3546060A1 (fr) * 2018-03-27 2019-10-02 DuPont Nutrition Biosciences ApS Procédé de séchage par pulvérisation de solutions de fucosyllactose et de compositions de produit correspondantes
EP3741770A1 (fr) * 2019-05-21 2020-11-25 Jennewein Biotechnologie GmbH Purification d'oligosaccharides d'un broth de fermentation au moyen de la filtration
EP3789495A1 (fr) * 2019-09-03 2021-03-10 Jennewein Biotechnologie GmbH Production d'oligosaccharides sialylés dans des cellules de bacille
WO2021045968A1 (fr) * 2019-09-04 2021-03-11 Dupont Nutrition Biosciences Aps Procédé d'élimination d'un agent anti-mousse d'une solution comprenant un oligosaccharide de lait humain et compositions associées
EP3821717A1 (fr) * 2019-11-15 2021-05-19 Jennewein Biotechnologie GmbH Procede de sechage d'oligosaccharides de lait humain
GB2623899A (en) * 2019-12-11 2024-05-01 Mjn Us Holdings Llc Staged nutritional compositions containing human milk oligosaccharides and uses thereof
GB2590375B (en) * 2019-12-11 2024-05-08 Mjn Us Holdings Llc Staged nutritional compositions containing human milk oligosaccharides and uses thereof
WO2021124234A1 (fr) * 2019-12-19 2021-06-24 Glycom A/S Séparation d'oligosaccharides sialylés d'un bouillon de fermentation
EP4097118A4 (fr) * 2020-01-29 2024-02-28 DSM IP Assets B.V. Procédé de récupération et de purification d'oligosaccharides de lait humain
WO2021186258A1 (fr) * 2020-03-20 2021-09-23 Glycom A/S Procédés d'obtention d'un produit hmo solide, et produits hmo solides obtenus par ceux-ci
US20230212210A1 (en) * 2020-09-18 2023-07-06 Institute Of Process Engineering, Chinese Academy Of Sciences Sugar Chain and Compositions Thereof and Use Thereof in Prevention and/or Treatment of Coronavirus Infection
WO2022096613A1 (fr) * 2020-11-09 2022-05-12 Basf Se Obtention de solutions de hmo hautement concentrées par osmose inverse
KR102435547B1 (ko) 2020-12-11 2022-08-24 (주)에이피테크놀로지 푸코실락토스를 유효성분으로 함유하는 항바이러스 조성물
EP4346450A1 (fr) * 2021-06-04 2024-04-10 N.V. Nutricia Préparation pour nourrissons pour nourrir des nourrissons recevant la préparation pour nourrissons et du lait maternel humain
CN114014896B (zh) * 2021-10-09 2023-12-05 中国科学院合肥物质科学研究院 一种高纯度3`-唾液酸乳糖的分离纯化方法
CN114539433B (zh) * 2021-12-29 2022-11-01 北京三元食品股份有限公司 一种乳低聚糖的制备方法及制备的低聚糖粉、食品
WO2023219437A1 (fr) 2022-05-11 2023-11-16 (주)에이피테크놀로지 Procédé de production de lacto-n-tétraose et de lacto-n-néotétraose à l'aide de corynebacterium glutamicum
KR102645729B1 (ko) 2022-05-11 2024-03-12 (주)에이피테크놀로지 코리네박테리움 글루타미쿰을 이용한 락토-n-테트라오스 및 락토-n-네오테트라오스의 생산 방법
KR20240081664A (ko) * 2022-11-30 2024-06-10 씨제이제일제당 (주) 발효 제품 제조 공정 및 제조 장치
CN117088923B (zh) * 2023-10-20 2024-02-13 山东星光首创生物科技有限公司 一种高流动性2’-岩藻糖基乳糖的生产方法

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003047402A (ja) 2001-08-06 2003-02-18 Meiji Milk Prod Co Ltd 中性オリゴ糖含有育児用調製乳
CN102257128A (zh) 2008-12-19 2011-11-23 詹内怀恩生物技术股份有限公司 岩藻糖化化合物的合成
GB0904562D0 (en) * 2009-03-17 2009-04-29 Separation Technologies Invest Isolation and purification of components of whey
CN102822186A (zh) * 2010-02-19 2012-12-12 格礼卡姆股份公司 6’-o-唾液乳糖的制备和中间体
WO2011136647A1 (fr) 2010-04-27 2011-11-03 N.V. Nutricia Utilisation de 6'-sialyl-lactose dans la nutrition d'un nourrisson et d'un petit enfant
WO2011150939A1 (fr) 2010-06-01 2011-12-08 Glycom A/S Formes polymorphiques du 2'-o-fucosyllactose et leurs procédés de production
EP2455387A1 (fr) 2010-11-23 2012-05-23 Nestec S.A. Mélange oligosaccharide et produit alimentaire comportant ce mélange, spécialement une formule pour enfants
CN102154163A (zh) 2010-12-31 2011-08-17 朱莉 一种3′-唾液酸乳糖的制备方法
US20120171166A1 (en) * 2010-12-31 2012-07-05 Abbott Laboratories Synbiotic combination of probiotic and human milk oligosaccharides to promote growth of beneficial microbiota
DK2479263T3 (da) 2011-01-20 2014-02-03 Jennewein Biotechnologie Gmbh Nye fucosyltransferaser og deres anvendelser
CA2827313C (fr) * 2011-02-16 2023-08-22 Glycosyn LLC Biosynthese d'oligosaccharides de lait humain dans des bacteries manipulees
EP2522232A1 (fr) 2011-05-13 2012-11-14 Nestec S.A. Produits nutritifs comportant des oligosaccharides de lait humain et procédés de fabrication associés
TW201249349A (en) * 2011-05-24 2012-12-16 Nestec Sa Milk oligosaccharide-galactooligosaccharide composition for infant formula containing the soluble oligosaccharide fraction present in milk, and having a low level of monosaccharides, and a process to produce the composition
DE202013012827U1 (de) * 2012-06-14 2020-02-13 Glycom A/S Verbesserung der Stabilität und Reinheit sowie Erhöhung der Bioverfügbarkeit von menschlichen Milch-Oligosacchariden oder Vorläufern oder Mischungen davon
CN104812768B (zh) 2012-11-13 2019-06-21 格礼卡姆股份公司 晶体3-o-岩藻糖基乳糖
WO2014086373A1 (fr) * 2012-12-07 2014-06-12 Glycom A/S Cristallisation d'oligosaccharides de lait humain
US11160817B2 (en) 2012-12-18 2021-11-02 Abbott Laboratories Nutritional compositions comprising neuroprotective dietary oligosaccharides
WO2014094783A1 (fr) 2012-12-18 2014-06-26 Glycom A/S Nouveaux polymorphes de lnnt
TW201438719A (zh) * 2012-12-18 2014-10-16 Abbott Lab 改善壓力症狀之母乳寡糖
EP2845905B8 (fr) 2013-09-10 2021-07-14 Chr. Hansen HMO GmbH Production d'oligosaccharides
EP2857410A1 (fr) * 2013-10-04 2015-04-08 Jennewein Biotechnologie GmbH Procédé de purification de 2´-fucosyllactose utilisant la chromatographie à lit mobile simulé
EP3082827A1 (fr) * 2013-11-15 2016-10-26 Nestec S.A. Composition pour la prévention ou le traitement d'allergies chez des nourrissons d'une mère non sécrétrice ou nourris par une mère non sécrétrice par l'utilisation d'oligosaccharides fucosylés en particulier chez des enfants présentant un risque ou nés par césarienne
CN105722515A (zh) 2013-11-15 2016-06-29 雀巢产品技术援助有限公司 用于预防或治疗有风险婴儿或幼儿的urt感染的组合物
AU2014350157A1 (en) * 2013-11-15 2016-04-14 Nestec S.A. Compositions for use in the prevention or treatment of necrotizing enterocolitis in infants and young children
AU2014350156A1 (en) 2013-11-15 2016-04-14 Nestec S.A. Compositions for use in the prevention or treatment of necrotizing enterocolitis in infants or young children born by C-section
ES2701163T3 (es) * 2014-01-20 2019-02-21 Jennewein Biotechnologie Gmbh Procedimiento para la purificación eficiente de oligosacáridos de la leche humana (HMO) neutros a partir de la fermentación microbiana
EP3461890A1 (fr) 2014-03-31 2019-04-03 Jennewein Biotechnologie GmbH Fermentation totale d'oligosaccharides
US20150305385A1 (en) * 2014-04-25 2015-10-29 Mead Johnson Nutrition Company Pediatric nutritional composition with human milk oligosaccahrides, prebiotics and probiotics
CA2960835A1 (fr) 2014-09-09 2016-03-17 Glycosyn LLC Alpha (1,3) fucosyltransferases destinees a etre utilisees dans la production d'oligosaccharides fucosyles
JP7182872B2 (ja) 2014-10-29 2022-12-05 グリコム・アクティーゼルスカブ 過敏性腸症候群の治療のための合成組成物および方法
US10500221B2 (en) 2014-12-05 2019-12-10 Glycom A/S Crystalline difucosyllactose
WO2017043382A1 (fr) 2015-09-09 2017-03-16 カルソニックカンセイ株式会社 Dispositif de chauffage de fluide et son procédé de fabrication
US11957148B2 (en) * 2015-12-15 2024-04-16 Societe Des Produits Nestle S.A. Mixture of human milk oligosaccharides(HMOs)
DK3390422T3 (da) 2015-12-17 2023-11-27 Glycom As Krystalformer af lnt
US10829508B2 (en) * 2015-12-18 2020-11-10 Glycom A/S Fermentative production of oligosaccharides
CN105532883A (zh) * 2015-12-21 2016-05-04 海普诺凯营养品有限公司 一种婴幼儿用配方羊奶粉及其制备方法
US10899782B2 (en) * 2016-03-07 2021-01-26 Glycom A/S Separation of oligosaccharides from fermentation broth
WO2017198276A1 (fr) * 2016-05-19 2017-11-23 Glycom A/S Composition synthétique
EP3450443A1 (fr) * 2017-08-29 2019-03-06 Jennewein Biotechnologie GmbH Procédé de purification d'oligosaccharides sialylés
EP3486326A1 (fr) 2017-11-21 2019-05-22 Jennewein Biotechnologie GmbH Procédé de purification d'acide n-acétylneuraminique à partir d'un bouillon de fermentation
EP3494805A1 (fr) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Tétrasaccharide séché en pulvérisation
EP3494807A1 (fr) 2017-12-11 2019-06-12 Jennewein Biotechnologie GmbH Sialyllactose séché par pulvérisation
EP3494804A1 (fr) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH 3-fucosyllactose séché en pulvérisation
EP3494806A1 (fr) 2017-12-08 2019-06-12 Jennewein Biotechnologie GmbH Lacto-n-fucopentaose séché par pulvérisation

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