SG11201905510XA - Compositions and methods for reducing bioburden in chromatography - Google Patents
Compositions and methods for reducing bioburden in chromatographyInfo
- Publication number
- SG11201905510XA SG11201905510XA SG11201905510XA SG11201905510XA SG11201905510XA SG 11201905510X A SG11201905510X A SG 11201905510XA SG 11201905510X A SG11201905510X A SG 11201905510XA SG 11201905510X A SG11201905510X A SG 11201905510XA SG 11201905510X A SG11201905510X A SG 11201905510XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- tarrytown
- regeneron
- river road
- old saw
- Prior art date
Links
- 238000004587 chromatography analysis Methods 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 5
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 240000008100 Brassica rapa Species 0.000 abstract 1
- 238000001042 affinity chromatography Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
- B01D15/203—Equilibration or regeneration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/26—Accessories or devices or components used for biocidal treatment
- A61L2/28—Devices for testing the effectiveness or completeness of sterilisation, e.g. indicators which change colour
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/20—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/50—Conditioning of the sorbent material or stationary liquid
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/10—Terrestrial scenes
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/40—Scenes; Scene-specific elements in video content
- G06V20/46—Extracting features or characteristics from the video content, e.g. video fingerprints, representative shots or key frames
-
- G—PHYSICS
- G08—SIGNALLING
- G08G—TRAFFIC CONTROL SYSTEMS
- G08G1/00—Traffic control systems for road vehicles
- G08G1/01—Detecting movement of traffic to be counted or controlled
- G08G1/017—Detecting movement of traffic to be counted or controlled identifying vehicles
- G08G1/0175—Detecting movement of traffic to be counted or controlled identifying vehicles by photographing vehicles, e.g. when violating traffic rules
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
- G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
- G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V20/00—Scenes; Scene-specific elements
- G06V20/60—Type of objects
- G06V20/62—Text, e.g. of license plates, overlay texts or captions on TV images
- G06V20/625—License plates
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
- G06V2201/00—Indexing scheme relating to image or video recognition or understanding
- G06V2201/08—Detecting or categorising vehicles
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Multimedia (AREA)
- Theoretical Computer Science (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Peptides Or Proteins (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762452140P | 2017-01-30 | 2017-01-30 | |
| PCT/US2018/015764 WO2018140887A1 (en) | 2017-01-30 | 2018-01-29 | Method for reducing bioburden in chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201905510XA true SG11201905510XA (en) | 2019-08-27 |
Family
ID=61249704
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201905510XA SG11201905510XA (en) | 2017-01-30 | 2018-01-29 | Compositions and methods for reducing bioburden in chromatography |
| SG10202102298YA SG10202102298YA (en) | 2017-01-30 | 2018-01-29 | Compositions and methods for reducing bioburden in chromatography |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202102298YA SG10202102298YA (en) | 2017-01-30 | 2018-01-29 | Compositions and methods for reducing bioburden in chromatography |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US10925986B2 (he) |
| EP (1) | EP3573734A1 (he) |
| JP (4) | JP7479151B2 (he) |
| KR (2) | KR20230041082A (he) |
| CN (2) | CN110267721B (he) |
| AU (2) | AU2018212974B2 (he) |
| CA (2) | CA3047790A1 (he) |
| IL (4) | IL299270B1 (he) |
| MX (2) | MX2019008996A (he) |
| SG (2) | SG11201905510XA (he) |
| WO (1) | WO2018140887A1 (he) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI709570B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析法及製法 |
| TWI709569B (zh) | 2014-01-17 | 2020-11-11 | 美商健臻公司 | 無菌層析樹脂及其用於製造方法的用途 |
| SG11201905510XA (en) * | 2017-01-30 | 2019-08-27 | Regeneron Pharma | Compositions and methods for reducing bioburden in chromatography |
| BR112021003420A2 (pt) * | 2018-08-31 | 2021-05-18 | Genzyme Corporation | resina cromatográfica estéril e uso da mesma em processos de manufatura |
| US20220220423A1 (en) * | 2019-04-17 | 2022-07-14 | Bristol-Myers Squibb Company | Methods for regenerating chromatography resins |
| EP4334010A1 (en) * | 2021-05-07 | 2024-03-13 | Genzyme Corporation | Composition and methods for sanitization |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5202246A (en) * | 1989-08-16 | 1993-04-13 | Armour Pharmaceutical Company | Treatment of immobilized matrices for preparation of pharmaceutical and biological products with anti-microbial agents to remove pyrogen-producing organisms and pyrogens |
| AT408191B (de) * | 1991-08-19 | 2001-09-25 | Haemosan Erzeugung Pharmazeuti | Verfahren zur inaktivierung von prionen |
| DE4321904B4 (de) * | 1993-07-01 | 2013-05-16 | Qiagen Gmbh | Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen |
| US5643755A (en) * | 1994-10-07 | 1997-07-01 | Regeneron Pharmaceuticals Inc. | Nucleic acid encoding tie-2 ligand |
| CA2191351A1 (en) | 1994-05-31 | 1995-12-07 | Alois Jungbauer | Sterilization of liquid chromatography resins |
| US5814464A (en) * | 1994-10-07 | 1998-09-29 | Regeneron Pharma | Nucleic acids encoding TIE-2 ligand-2 |
| US5650496A (en) * | 1995-04-14 | 1997-07-22 | Cephalon, Inc. | IGF-I purification process |
| US6022694A (en) * | 1997-04-04 | 2000-02-08 | Regeneron Pharmaceuticals, Inc. | Assay for ligands to tyrosine kinase receptors |
| AU5142899A (en) * | 1999-02-17 | 2000-09-04 | Resolution Pharmaceuticals Inc. | Immobilized labeling compounds and methods |
| MXPA02003517A (es) | 1999-10-08 | 2004-09-10 | Vi Technologies Inc | Composiciones sanguineas desprovistas de isoaglutinina y metodo para elaborarlas. |
| EP1358202A2 (en) * | 2000-02-08 | 2003-11-05 | The Regents Of The University Of Michigan | Protein separation and display |
| WO2002032537A2 (en) * | 2000-10-13 | 2002-04-25 | Eli Lilly And Company | Improved method of expanded bed chromatography |
| SE0004929D0 (sv) * | 2000-12-29 | 2000-12-29 | Apbiotech Ab | A method for producing liquid chromatography matrices |
| DE10155984A1 (de) * | 2001-11-15 | 2003-05-28 | Boehringer Ingelheim Pharma | Verfahren zur Reduktion des Liganden-leakage von Affinitätschromatographie-Matrices |
| US6913695B2 (en) * | 2003-07-08 | 2005-07-05 | Bayer Healthcare Llc | Sanitization of chromatographic media |
| WO2006033634A1 (en) * | 2004-09-22 | 2006-03-30 | Ge Healthcare Bio-Sciences Ab | Method of preparing a chromatography matrix |
| CA2583578C (en) * | 2004-10-21 | 2014-04-01 | Ge Healthcare Bio-Sciences Ab | Chromatography ligand |
| WO2007109163A2 (en) * | 2006-03-16 | 2007-09-27 | Amgen Inc | Wash buffer and method of using |
| EP2043776A4 (en) * | 2006-05-29 | 2009-12-30 | Ge Healthcare Bio Sciences Ab | PREPARATION OF MONOLITHIC OBJECTS |
| MX2009002576A (es) * | 2006-09-08 | 2009-03-20 | Wyeth Corp | Lavado de arginina en purificacion de proteina utilizando cromatografia de afinidad. |
| JP5102847B2 (ja) | 2007-02-01 | 2012-12-19 | アバントール パフォーマンス マテリアルズ， インコーポレイテッド | クロマトグラフィー媒体およびクロマトグラフィー器材保存溶液ならびにそれらの使用 |
| DE102008030142A1 (de) * | 2008-06-27 | 2009-12-31 | Qiagen Gmbh | Verfahren zur Proteinaufreinigung unter denaturierenden Bedingungen |
| US8338577B2 (en) * | 2008-09-15 | 2012-12-25 | Emd Millipore Corporation | Methods for quantifying protein leakage from protein based affinity chromatography resins |
| WO2010127069A1 (en) * | 2009-04-29 | 2010-11-04 | Schering Corporation | Antibody purification |
| AU2010351576B2 (en) * | 2010-04-23 | 2014-08-14 | FinaBioSolutions, LLC | Simple method for simultaneous removal of multiple impurities from culture supernatants to ultralow levels |
| JP6023715B2 (ja) * | 2010-10-11 | 2016-11-09 | アッヴィ・バハマズ・リミテッド | タンパク質の精製方法 |
| US9102709B1 (en) * | 2011-07-08 | 2015-08-11 | Biogen Ma Inc. | Regeneration of chromatography material |
| US20150044718A1 (en) * | 2012-02-29 | 2015-02-12 | Hoffmann-La Roche Inc. | On-column enzymatic cleavage |
| EP2656892A1 (en) | 2012-04-23 | 2013-10-30 | Merck Patent GmbH | Chromatography method |
| US20140154270A1 (en) * | 2012-05-21 | 2014-06-05 | Chen Wang | Purification of non-human antibodies using kosmotropic salt enhanced protein a affinity chromatography |
| JP5782533B2 (ja) * | 2013-03-28 | 2015-09-24 | 富士フイルム株式会社 | クロマトグラフ方法及びクロマトグラフキット |
| DK3041857T3 (da) | 2013-09-04 | 2019-07-22 | Emd Millipore Corp | Protein a-kromatografi |
| CN105848746B (zh) | 2013-09-05 | 2019-07-09 | 豪夫迈·罗氏有限公司 | 用于层析重复利用的方法 |
| JP5910696B1 (ja) * | 2014-10-06 | 2016-04-27 | 栗田工業株式会社 | 逆浸透膜の洗浄剤、洗浄液、および洗浄方法 |
| GB201503578D0 (en) * | 2015-03-03 | 2015-04-15 | Ge Healthcare Bio Sciences Ab | Sanitization method for affinity chromatography matrices |
| WO2016149088A1 (en) | 2015-03-13 | 2016-09-22 | Bristol-Myers Squibb Company | Use of alkaline washes during chromatography to remove impurities |
| US20170066839A1 (en) * | 2015-09-08 | 2017-03-09 | Merck Patent Gmbh | Novel affinity chromatography media for removal of anti-a and/or anti-b antibodies |
| CN107064286B (zh) * | 2017-01-16 | 2018-07-20 | 常州市疾病预防控制中心 | 革兰氏阳性及阴性菌质谱检测试剂盒及快速鉴定的方法 |
| SG11201905510XA (en) * | 2017-01-30 | 2019-08-27 | Regeneron Pharma | Compositions and methods for reducing bioburden in chromatography |
-
2018
- 2018-01-29 SG SG11201905510XA patent/SG11201905510XA/en unknown
- 2018-01-29 MX MX2019008996A patent/MX2019008996A/es unknown
- 2018-01-29 SG SG10202102298YA patent/SG10202102298YA/en unknown
- 2018-01-29 WO PCT/US2018/015764 patent/WO2018140887A1/en unknown
- 2018-01-29 IL IL299270A patent/IL299270B1/he unknown
- 2018-01-29 CA CA3047790A patent/CA3047790A1/en active Pending
- 2018-01-29 KR KR1020237008226A patent/KR20230041082A/ko not_active Application Discontinuation
- 2018-01-29 US US15/882,845 patent/US10925986B2/en active Active
- 2018-01-29 CN CN201880008672.3A patent/CN110267721B/zh active Active
- 2018-01-29 IL IL312404A patent/IL312404A/he unknown
- 2018-01-29 AU AU2018212974A patent/AU2018212974B2/en active Active
- 2018-01-29 CA CA3233933A patent/CA3233933A1/en active Pending
- 2018-01-29 CN CN202210115636.5A patent/CN114470872A/zh active Pending
- 2018-01-29 KR KR1020197024930A patent/KR102586771B1/ko active IP Right Grant
- 2018-01-29 JP JP2019540624A patent/JP7479151B2/ja active Active
- 2018-01-29 EP EP18706335.9A patent/EP3573734A1/en active Pending
-
2019
- 2019-07-14 IL IL268029A patent/IL268029B/he unknown
- 2019-07-29 MX MX2023008870A patent/MX2023008870A/es unknown
-
2021
- 2021-01-20 US US17/153,205 patent/US11369707B2/en active Active
- 2021-10-24 IL IL287543A patent/IL287543A/he unknown
- 2021-12-21 JP JP2021206920A patent/JP7361754B2/ja active Active
-
2022
- 2022-06-20 JP JP2022098756A patent/JP2022137067A/ja active Pending
- 2022-06-24 US US17/848,936 patent/US11717586B2/en active Active
-
2023
- 2023-07-05 US US18/218,532 patent/US20230343086A1/en active Pending
- 2023-10-20 JP JP2023181001A patent/JP2023174943A/ja active Pending
- 2023-11-24 AU AU2023270342A patent/AU2023270342A1/en active Pending
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