SG11201901937WA - Pyridine compound - Google Patents

Pyridine compound

Info

Publication number
SG11201901937WA
SG11201901937WA SG11201901937WA SG11201901937WA SG11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA SG 11201901937W A SG11201901937W A SG 11201901937WA
Authority
SG
Singapore
Prior art keywords
chuo
tokyo
limited
international
honcho
Prior art date
Application number
SG11201901937WA
Other languages
English (en)
Inventor
Hiroaki Inagaki
Yoshihiro Shibata
Hidenori Namiki
Hideaki Kageji
Kiyoshi Nakayama
Yasuyuki Kaneta
Original Assignee
Daiichi Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Sankyo Co Ltd filed Critical Daiichi Sankyo Co Ltd
Publication of SG11201901937WA publication Critical patent/SG11201901937WA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4709Non-condensed quinolines and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
SG11201901937WA 2016-09-29 2017-09-28 Pyridine compound SG11201901937WA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016191725A JP2018052878A (ja) 2016-09-29 2016-09-29 ピリジン化合物
PCT/GB2017/052913 WO2018060714A1 (fr) 2016-09-29 2017-09-28 Composé de pyridine

Publications (1)

Publication Number Publication Date
SG11201901937WA true SG11201901937WA (en) 2019-04-29

Family

ID=60020249

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201901937WA SG11201901937WA (en) 2016-09-29 2017-09-28 Pyridine compound

Country Status (32)

Country Link
US (2) US10851092B2 (fr)
EP (2) EP3519398B1 (fr)
JP (2) JP2018052878A (fr)
KR (1) KR102520543B1 (fr)
CN (2) CN113788824A (fr)
AU (2) AU2017335242C1 (fr)
BR (1) BR112019006047A2 (fr)
CA (1) CA3035860A1 (fr)
CL (1) CL2019000844A1 (fr)
CO (1) CO2019004034A2 (fr)
CY (1) CY1123988T1 (fr)
DK (1) DK3519398T3 (fr)
EA (1) EA037103B1 (fr)
EC (1) ECSP19030134A (fr)
ES (1) ES2868748T3 (fr)
HR (1) HRP20210447T1 (fr)
HU (1) HUE054824T2 (fr)
IL (1) IL265630B (fr)
LT (1) LT3519398T (fr)
MA (2) MA46337B1 (fr)
MD (1) MD3519398T2 (fr)
MX (1) MX2019003747A (fr)
PE (1) PE20190805A1 (fr)
PH (1) PH12019500480A1 (fr)
PL (1) PL3519398T3 (fr)
PT (1) PT3519398T (fr)
RS (1) RS61640B1 (fr)
SG (1) SG11201901937WA (fr)
SI (1) SI3519398T1 (fr)
UA (1) UA123964C2 (fr)
WO (1) WO2018060714A1 (fr)
ZA (1) ZA201902232B (fr)

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JP6807385B2 (ja) 2015-11-02 2021-01-06 ブループリント メディシンズ コーポレイション Retの阻害剤
JP2018052878A (ja) * 2016-09-29 2018-04-05 第一三共株式会社 ピリジン化合物
CN111615514B (zh) 2018-01-18 2022-10-11 奥瑞生物药品公司 作为ret激酶抑制剂的取代的吡唑并[4,3-c]吡啶化合物
JP7060694B2 (ja) 2018-01-18 2022-04-26 アレイ バイオファーマ インコーポレイテッド Retキナーゼ阻害剤としての置換ピロロ[2,3-d]ピリミジン化合物
CA3096043A1 (fr) 2018-04-03 2019-10-10 Blueprint Medicines Corporation Inhibiteur de ret destine a etre utilise dans le traitement du cancer presentant une alteration du ret
US20220143049A1 (en) 2019-03-21 2022-05-12 Onxeo A dbait molecule in combination with kinase inhibitor for the treatment of cancer
EP4054579A1 (fr) 2019-11-08 2022-09-14 Institut National de la Santé et de la Recherche Médicale (INSERM) Méthodes pour le traitement de cancers qui ont acquis une résistance aux inhibiteurs de kinase
IL293055A (en) * 2019-11-18 2022-07-01 Chugai Pharmaceutical Co Ltd Ret kinase inhibitors in combination with cyclin-dependent kinase 4 ret/or cyclin-dependent kinase 6 (cdk 4/6) inhibitors for use in cancer treatment
CN113121524B (zh) 2019-12-31 2023-04-25 南京创济生物医药有限公司 杂环亚砜亚胺化合物及其中间体、制备方法和应用
WO2021148581A1 (fr) 2020-01-22 2021-07-29 Onxeo Nouvelle molécule dbait et son utilisation
WO2021164741A1 (fr) * 2020-02-20 2021-08-26 南京明德新药研发有限公司 Composé de bisamide de phényle
CN115210226B (zh) * 2020-02-20 2024-01-09 广州白云山医药集团股份有限公司白云山制药总厂 喹啉类化合物
WO2022238706A1 (fr) 2021-05-14 2022-11-17 Bp Asset Viii, Inc. Inhibiteur de ret pour le traitement du cancer médullaire de la thyroïde à altération de ret ou du cancer du poumon non à petites cellules à altération de ret
AU2022463015A1 (en) 2021-10-22 2024-05-09 Tract Pharmaceuticals, Inc. Methods and compositions for treating chronic inflammatory injury, metaplasia, dysplasia and cancers of epithelial tissues
CN115090331B (zh) * 2022-07-21 2023-05-16 扬州大学 超分子手性催化剂、其制备方法及其催化d-a反应的应用

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TWI284639B (en) 2000-01-24 2007-08-01 Shionogi & Co A compound having thrombopoietin receptor agonistic effect
US7749999B2 (en) 2003-09-11 2010-07-06 Itherx Pharmaceuticals, Inc. Alpha-ketoamides and derivatives thereof
EP1994024A2 (fr) 2006-03-02 2008-11-26 AstraZeneca AB Dérivés de la quinoline
EP1994023A1 (fr) 2006-03-02 2008-11-26 AstraZeneca AB Dérivés de la quinazoline
WO2007113565A1 (fr) 2006-04-06 2007-10-11 Astrazeneca Ab Dérivés de la naphtyridine comme agents anti-cancéreux
WO2007113548A1 (fr) 2006-04-06 2007-10-11 Astrazeneca Ab Dérivés de naphtyridine
FR2933700B1 (fr) 2008-07-08 2010-07-30 Sanofi Aventis Derives de pyridino-pyridinones, leur preparation et leur application en therapeutique
CN102333765B (zh) * 2009-02-27 2015-01-14 帝人制药株式会社 基于使用过渡金属催化剂的偶联法的苯基取代杂环衍生物的制造方法
EP2467137A1 (fr) 2009-08-19 2012-06-27 Ambit Biosciences Corporation Composés biaryles et procédés d utilisation de ceux-ci
CA2772301A1 (fr) 2009-08-25 2011-03-03 Abraxis Bioscience, Llc Pluritherapie avec des compositions nanoparticulaires de taxane et des inhibiteurs hedgehog
WO2011133728A2 (fr) 2010-04-23 2011-10-27 Kineta, Inc. Composés antiviraux
US9073895B2 (en) 2010-12-16 2015-07-07 Boehringer Ingelheim International Gmbh Biarylamide inhibitors of leukotriene production
EP2872493B1 (fr) 2012-07-13 2018-11-14 Indiana University Research and Technology Corporation 5,6,7-trimethoxy 4-phenyle quinoline-2-ones utilisables en vue du traitement de l'amyotrophie spinale
EA029296B1 (ru) * 2013-03-15 2018-03-30 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Пиридиновые производные в качестве ингибиторов реаранжированной в процессе трансфекции (ret) киназы
EP3039021A1 (fr) * 2013-08-30 2016-07-06 Ambit Biosciences Corporation Composés de biaryle acétamide et procédés d'utilisation de ceux-ci
GB201321146D0 (en) 2013-11-29 2014-01-15 Cancer Rec Tech Ltd Quinazoline compounds
TW201623239A (zh) * 2014-04-24 2016-07-01 田邊三菱製藥股份有限公司 新穎2-胺基-吡啶及2-胺基-嘧啶衍生物及其醫藥用途
JP6538154B2 (ja) * 2014-09-10 2019-07-03 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited Ret(rearranged during transfection)キナーゼ阻害剤としてのピリジン誘導体
AU2015316438B2 (en) * 2014-09-10 2018-05-24 Glaxosmithkline Intellectual Property Development Limited Novel compounds as Rearranged during Transfection (RET) inhibitors
WO2016061280A1 (fr) 2014-10-14 2016-04-21 La Jolla Institute Of Allergy & Immunology Inhibiteurs de la protéine tyrosine phosphatase de faible poids moléculaire et utilisations
CN104844589B (zh) 2014-12-26 2018-04-20 中国科学院合肥物质科学研究院 一种pi3k激酶抑制剂
US10202365B2 (en) * 2015-02-06 2019-02-12 Blueprint Medicines Corporation 2-(pyridin-3-yl)-pyrimidine derivatives as RET inhibitors
PT3322706T (pt) 2015-07-16 2021-03-08 Array Biopharma Inc Compostos de pirazolo[1,5-a]piridina substituídos como inibidores da quinase do ret
JP2018052878A (ja) * 2016-09-29 2018-04-05 第一三共株式会社 ピリジン化合物

Also Published As

Publication number Publication date
MA46337B1 (fr) 2021-04-30
JP2018052878A (ja) 2018-04-05
AU2021261899A1 (en) 2021-12-02
WO2018060714A1 (fr) 2018-04-05
MD3519398T2 (ro) 2021-05-31
PE20190805A1 (es) 2019-06-10
PH12019500480A1 (en) 2019-08-05
ES2868748T3 (es) 2021-10-21
CO2019004034A2 (es) 2019-07-10
MA46337A (fr) 2019-08-07
UA123964C2 (uk) 2021-06-30
CN110036007A (zh) 2019-07-19
EP3828178A1 (fr) 2021-06-02
CA3035860A1 (fr) 2018-04-05
DK3519398T3 (da) 2021-03-29
CN113788824A (zh) 2021-12-14
AU2017335242C1 (en) 2021-12-09
EP3519398B1 (fr) 2021-02-24
AU2017335242A1 (en) 2019-05-02
LT3519398T (lt) 2021-05-10
IL265630B (en) 2021-10-31
MX2019003747A (es) 2019-09-19
JP2019534871A (ja) 2019-12-05
ECSP19030134A (es) 2019-08-30
CL2019000844A1 (es) 2019-06-07
RS61640B1 (sr) 2021-04-29
KR20190086442A (ko) 2019-07-22
HUE054824T2 (hu) 2021-10-28
BR112019006047A2 (pt) 2019-06-25
PT3519398T (pt) 2021-03-24
MA54910A (fr) 2022-04-13
AU2017335242B2 (en) 2021-08-19
PL3519398T3 (pl) 2021-06-28
JP7098609B2 (ja) 2022-07-11
ZA201902232B (en) 2022-12-21
EP3519398A1 (fr) 2019-08-07
US10851092B2 (en) 2020-12-01
CN110036007B (zh) 2021-10-15
CY1123988T1 (el) 2022-05-27
EA201990833A1 (ru) 2019-10-31
KR102520543B1 (ko) 2023-04-10
SI3519398T1 (sl) 2021-07-30
EA037103B1 (ru) 2021-02-05
IL265630A (en) 2019-05-30
US20200039974A1 (en) 2020-02-06
US20210163464A1 (en) 2021-06-03
HRP20210447T1 (hr) 2021-07-23

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