SG11201900810WA - Composition for injection which can be used for treatment of heart diseases and contains fibroblasts, and method for producing fibroblast for therapy use - Google Patents
Composition for injection which can be used for treatment of heart diseases and contains fibroblasts, and method for producing fibroblast for therapy useInfo
- Publication number
- SG11201900810WA SG11201900810WA SG11201900810WA SG11201900810WA SG11201900810WA SG 11201900810W A SG11201900810W A SG 11201900810WA SG 11201900810W A SG11201900810W A SG 11201900810WA SG 11201900810W A SG11201900810W A SG 11201900810WA SG 11201900810W A SG11201900810W A SG 11201900810WA
- Authority
- SG
- Singapore
- Prior art keywords
- composition
- fibroblasts
- treatment
- injection
- heart diseases
- Prior art date
Links
- 210000002950 fibroblast Anatomy 0.000 title abstract 6
- 208000019622 heart disease Diseases 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000002347 injection Methods 0.000 title 1
- 239000007924 injection Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 208000020446 Cardiac disease Diseases 0.000 abstract 1
- 101000800116 Homo sapiens Thy-1 membrane glycoprotein Proteins 0.000 abstract 1
- 102100033523 Thy-1 membrane glycoprotein Human genes 0.000 abstract 1
- 210000005003 heart tissue Anatomy 0.000 abstract 1
- 239000007972 injectable composition Substances 0.000 abstract 1
- 230000007774 longterm Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000001338 necrotic effect Effects 0.000 abstract 1
- 238000011084 recovery Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/33—Fibroblasts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Hospice & Palliative Care (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017033624 | 2017-02-24 | ||
| PCT/JP2018/006795 WO2018155651A1 (ja) | 2017-02-24 | 2018-02-23 | 線維芽細胞を含む心臓疾患を治療するための注射用組成物、及び治療用線維芽細胞の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201900810WA true SG11201900810WA (en) | 2019-02-27 |
Family
ID=63253929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201900810WA SG11201900810WA (en) | 2017-02-24 | 2018-02-23 | Composition for injection which can be used for treatment of heart diseases and contains fibroblasts, and method for producing fibroblast for therapy use |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US11096969B2 (OSRAM) |
| EP (1) | EP3476395B1 (OSRAM) |
| JP (2) | JP6618066B2 (OSRAM) |
| KR (1) | KR102407387B1 (OSRAM) |
| CN (1) | CN109890398B (OSRAM) |
| AU (1) | AU2018223739B2 (OSRAM) |
| CA (1) | CA3032654A1 (OSRAM) |
| DK (1) | DK3476395T3 (OSRAM) |
| ES (1) | ES2885080T3 (OSRAM) |
| IL (1) | IL267958B2 (OSRAM) |
| SG (1) | SG11201900810WA (OSRAM) |
| WO (1) | WO2018155651A1 (OSRAM) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL281081B (en) | 2018-08-29 | 2022-07-01 | Metcela Inc | A method to generate fibroblast and fibroblastic mass positive for g-csf |
| CN109589337B (zh) | 2018-12-29 | 2022-04-26 | 南京艾尔普再生医学科技有限公司 | 心肌细胞制剂及其制备方法和应用 |
| CN115210361B (zh) * | 2020-03-04 | 2024-12-10 | 淋巴奥格尼克斯有限公司 | 促红细胞生成素产生能力增强的成纤维细胞、制造方法以及医药组合物 |
| IL305069A (en) * | 2021-03-04 | 2023-10-01 | Metcela Inc | Fibroblast beta-factor promotes lymphangiogenesis, and a pharmaceutical preparation containing it |
| JPWO2023037868A1 (OSRAM) * | 2021-09-08 | 2023-03-16 | ||
| EP4249585A1 (en) * | 2022-03-25 | 2023-09-27 | Technische Universität München - TUM | Heart tissue models, method of producing heart tissue models and uses of heart tissue models |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003901668A0 (en) * | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
| JP2005524496A (ja) * | 2002-05-08 | 2005-08-18 | ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア | 非破壊性心伝導ブロック形成用システム及び方法 |
| JP2005538945A (ja) * | 2002-05-08 | 2005-12-22 | ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア | 心不整脈を線維芽細胞で治療するためのシステム及び方法 |
| US20040161412A1 (en) * | 2002-08-22 | 2004-08-19 | The Cleveland Clinic Foundation | Cell-based VEGF delivery |
| US7470538B2 (en) * | 2002-12-05 | 2008-12-30 | Case Western Reserve University | Cell-based therapies for ischemia |
| EP1689284A4 (en) * | 2003-11-10 | 2010-03-17 | Symphony Medical Inc | METHOD FOR REGULATING VENTRICULAR RHYTHM IN AURICULAR FIBRILLATION PATIENTS |
| US8513011B2 (en) * | 2004-08-26 | 2013-08-20 | Biotech Research Ventures Pte Limited | Methods and compositions for culturing cardiomyocyte-like cells |
| ES2325715B1 (es) * | 2007-08-03 | 2010-06-17 | Genetrix, S.L. | Poblacion de celulas madre adultas derivadas de tejido adiposo cardiaco y su uso en regeneracion cardiaca. |
| JP5378743B2 (ja) | 2008-09-30 | 2013-12-25 | テルモ株式会社 | 医療用細胞シートの製造方法 |
| US8802144B2 (en) * | 2011-08-25 | 2014-08-12 | Wisconsin Alumni Research Foundation | 3-dimensional cardiac fibroblast derived extracellular matrix |
| JP5920741B2 (ja) | 2012-03-15 | 2016-05-18 | ｉＨｅａｒｔ Ｊａｐａｎ株式会社 | 人工多能性幹細胞から心筋および血管系混合細胞群を製造する方法 |
| WO2014039995A1 (en) * | 2012-09-07 | 2014-03-13 | Fibrocell Technologies, Inc. | Fibroblast compositions for treating cardial damage after an infarct |
| GB201309057D0 (en) | 2013-05-20 | 2013-07-03 | Cell Therapy Ltd | Method |
| KR20150009655A (ko) * | 2013-07-16 | 2015-01-27 | 학교법인 동아학숙 | Gcp-2 유전자를 과발현하는 지방 간엽줄기세포를 포함하는 허혈성 질환 치료용 조성물 |
| CN106661552B (zh) * | 2014-07-11 | 2020-07-07 | 玛土撤拉有限公司 | 心脏细胞培养材料 |
-
2018
- 2018-02-23 JP JP2019501845A patent/JP6618066B2/ja active Active
- 2018-02-23 EP EP18758465.1A patent/EP3476395B1/en active Active
- 2018-02-23 WO PCT/JP2018/006795 patent/WO2018155651A1/ja not_active Ceased
- 2018-02-23 CN CN201880003050.1A patent/CN109890398B/zh active Active
- 2018-02-23 AU AU2018223739A patent/AU2018223739B2/en active Active
- 2018-02-23 DK DK18758465.1T patent/DK3476395T3/da active
- 2018-02-23 CA CA3032654A patent/CA3032654A1/en active Pending
- 2018-02-23 SG SG11201900810WA patent/SG11201900810WA/en unknown
- 2018-02-23 ES ES18758465T patent/ES2885080T3/es active Active
- 2018-02-23 KR KR1020197003364A patent/KR102407387B1/ko active Active
-
2019
- 2019-01-31 US US16/263,321 patent/US11096969B2/en active Active
- 2019-07-09 IL IL267958A patent/IL267958B2/en unknown
- 2019-10-03 JP JP2019182761A patent/JP7072135B2/ja active Active
-
2021
- 2021-07-19 US US17/379,671 patent/US20210346436A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA3032654A1 (en) | 2018-08-30 |
| JP2019218408A (ja) | 2019-12-26 |
| CN109890398B (zh) | 2024-01-16 |
| EP3476395A4 (en) | 2020-02-26 |
| IL267958B1 (en) | 2023-04-01 |
| JPWO2018155651A1 (ja) | 2019-11-07 |
| KR20190117468A (ko) | 2019-10-16 |
| EP3476395A1 (en) | 2019-05-01 |
| EP3476395B1 (en) | 2021-07-21 |
| JP6618066B2 (ja) | 2019-12-11 |
| AU2018223739A1 (en) | 2019-02-14 |
| US11096969B2 (en) | 2021-08-24 |
| CN109890398A (zh) | 2019-06-14 |
| ES2885080T3 (es) | 2021-12-13 |
| US20190224250A1 (en) | 2019-07-25 |
| IL267958B2 (en) | 2023-08-01 |
| AU2018223739B2 (en) | 2023-06-22 |
| KR102407387B1 (ko) | 2022-06-10 |
| US20210346436A1 (en) | 2021-11-11 |
| DK3476395T3 (da) | 2021-08-16 |
| JP7072135B2 (ja) | 2022-05-20 |
| IL267958A (en) | 2019-09-26 |
| WO2018155651A1 (ja) | 2018-08-30 |
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