DK3476395T3 - Injicerbar sammensætning omfattende fibroblaster til anvendelse i behandlingen af hjertesygdomme - Google Patents

Injicerbar sammensætning omfattende fibroblaster til anvendelse i behandlingen af hjertesygdomme Download PDF

Info

Publication number
DK3476395T3
DK3476395T3 DK18758465.1T DK18758465T DK3476395T3 DK 3476395 T3 DK3476395 T3 DK 3476395T3 DK 18758465 T DK18758465 T DK 18758465T DK 3476395 T3 DK3476395 T3 DK 3476395T3
Authority
DK
Denmark
Prior art keywords
treatment
composition including
heart diseases
including fibroblasts
injectible composition
Prior art date
Application number
DK18758465.1T
Other languages
English (en)
Inventor
Takahiro Iwamiya
Original Assignee
Metcela Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metcela Inc filed Critical Metcela Inc
Application granted granted Critical
Publication of DK3476395T3 publication Critical patent/DK3476395T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/33Fibroblasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK18758465.1T 2017-02-24 2018-02-23 Injicerbar sammensætning omfattende fibroblaster til anvendelse i behandlingen af hjertesygdomme DK3476395T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017033624 2017-02-24
PCT/JP2018/006795 WO2018155651A1 (ja) 2017-02-24 2018-02-23 線維芽細胞を含む心臓疾患を治療するための注射用組成物、及び治療用線維芽細胞の製造方法

Publications (1)

Publication Number Publication Date
DK3476395T3 true DK3476395T3 (da) 2021-08-16

Family

ID=63253929

Family Applications (1)

Application Number Title Priority Date Filing Date
DK18758465.1T DK3476395T3 (da) 2017-02-24 2018-02-23 Injicerbar sammensætning omfattende fibroblaster til anvendelse i behandlingen af hjertesygdomme

Country Status (12)

Country Link
US (2) US11096969B2 (da)
EP (1) EP3476395B1 (da)
JP (2) JP6618066B2 (da)
KR (1) KR102407387B1 (da)
CN (1) CN109890398B (da)
AU (1) AU2018223739B2 (da)
CA (1) CA3032654A1 (da)
DK (1) DK3476395T3 (da)
ES (1) ES2885080T3 (da)
IL (1) IL267958B2 (da)
SG (1) SG11201900810WA (da)
WO (1) WO2018155651A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019332400A1 (en) 2018-08-29 2021-04-01 Metcela Inc. Method for producing fibroblast, and G-CSF-positive fibroblast mass
CN109589337B (zh) * 2018-12-29 2022-04-26 南京艾尔普再生医学科技有限公司 心肌细胞制剂及其制备方法和应用
WO2021177387A1 (ja) 2020-03-04 2021-09-10 株式会社メトセラ エリスロポエチン産生能が亢進された線維芽細胞
EP4249585A1 (en) * 2022-03-25 2023-09-27 Technische Universität München - TUM Heart tissue models, method of producing heart tissue models and uses of heart tissue models

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003901668A0 (en) * 2003-03-28 2003-05-01 Medvet Science Pty. Ltd. Non-haemopoietic precursor cells
AU2003239418B2 (en) * 2002-05-08 2008-01-31 The Regents Of The University Of California System and method for forming a non-ablative cardiac conduction block
JP2005538945A (ja) * 2002-05-08 2005-12-22 ザ リージェンツ オブ ザ ユニヴァーシティー オブ カリフォルニア 心不整脈を線維芽細胞で治療するためのシステム及び方法
US20040161412A1 (en) * 2002-08-22 2004-08-19 The Cleveland Clinic Foundation Cell-based VEGF delivery
US7470538B2 (en) * 2002-12-05 2008-12-30 Case Western Reserve University Cell-based therapies for ischemia
JP2007520259A (ja) * 2003-11-10 2007-07-26 シンフォニー メディカル, インコーポレイテッド 心房細動患者における心室速度を制御するための方法
US8513011B2 (en) * 2004-08-26 2013-08-20 Biotech Research Ventures Pte Limited Methods and compositions for culturing cardiomyocyte-like cells
ES2325715B1 (es) * 2007-08-03 2010-06-17 Genetrix, S.L. Poblacion de celulas madre adultas derivadas de tejido adiposo cardiaco y su uso en regeneracion cardiaca.
JP5378743B2 (ja) 2008-09-30 2013-12-25 テルモ株式会社 医療用細胞シートの製造方法
US8802144B2 (en) * 2011-08-25 2014-08-12 Wisconsin Alumni Research Foundation 3-dimensional cardiac fibroblast derived extracellular matrix
WO2013137491A1 (ja) 2012-03-15 2013-09-19 国立大学法人京都大学 人工多能性幹細胞から心筋および血管系混合細胞群を製造する方法
WO2014039995A1 (en) * 2012-09-07 2014-03-13 Fibrocell Technologies, Inc. Fibroblast compositions for treating cardial damage after an infarct
GB201309057D0 (en) * 2013-05-20 2013-07-03 Cell Therapy Ltd Method
KR20150009655A (ko) * 2013-07-16 2015-01-27 학교법인 동아학숙 Gcp-2 유전자를 과발현하는 지방 간엽줄기세포를 포함하는 허혈성 질환 치료용 조성물
KR102263824B1 (ko) * 2014-07-11 2021-06-10 가부시키가이샤 메토세라 심장 세포 배양 재료

Also Published As

Publication number Publication date
WO2018155651A1 (ja) 2018-08-30
AU2018223739B2 (en) 2023-06-22
JP6618066B2 (ja) 2019-12-11
US11096969B2 (en) 2021-08-24
JP2019218408A (ja) 2019-12-26
EP3476395B1 (en) 2021-07-21
US20210346436A1 (en) 2021-11-11
CN109890398A (zh) 2019-06-14
EP3476395A4 (en) 2020-02-26
CN109890398B (zh) 2024-01-16
KR102407387B1 (ko) 2022-06-10
KR20190117468A (ko) 2019-10-16
ES2885080T3 (es) 2021-12-13
EP3476395A1 (en) 2019-05-01
JPWO2018155651A1 (ja) 2019-11-07
SG11201900810WA (en) 2019-02-27
IL267958A (en) 2019-09-26
JP7072135B2 (ja) 2022-05-20
CA3032654A1 (en) 2018-08-30
IL267958B2 (en) 2023-08-01
IL267958B1 (en) 2023-04-01
AU2018223739A1 (en) 2019-02-14
US20190224250A1 (en) 2019-07-25

Similar Documents

Publication Publication Date Title
DK3889145T3 (da) 8-cyano-5-piperidino-quinoliner som TLR7/8-antagonister og anvendelser deraf til behandling af immunsygdomme
EP3349783C0 (en) COMPOSITIONS AND METHODS ASSOCIATED WITH THE TREATMENT OF DISEASES
DK3173092T3 (da) Rna-holdig sammensætning til behandling af tumorsygdomme
IL255509B (en) Compounds as modulators of ccr2, pharmaceutical preparations containing them and their use in the treatment of diseases
DK3377637T3 (da) Sammensætninger til anvendelse i fremgangsmåder til behandling af sår, lidelser og sygdomme i huden
DK3307262T3 (da) Forbindelser til anvendelse ved behandling af neuromuskulære lidelser
DK3882250T3 (da) Tetrahydropyranyl-amino-pyrrolopyrimidinon til anvendelse i behandling af btk-medierede forstyrrelser
ZA201902275B (en) Topical dressing composition for the treatment of damaged skin tissue
ZA201904522B (en) Heterocyclic inhibitors of mct4
DK2945642T3 (da) Faktor 1 protein til anvendelse i behandling eller forebyggelse af sygdomme
DK3658132T3 (da) Sammensætninger omfattende aminosyrer til anvendelse ved behandling af mitokondrielle dysfunktion-relaterede sygdomme
DK3476395T3 (da) Injicerbar sammensætning omfattende fibroblaster til anvendelse i behandlingen af hjertesygdomme
EP3538119A4 (en) COMPOSITIONS AND METHODS FOR TREATING SKIN DISEASES AND MAINTAINING HEALTHY SKIN
EP3328864A4 (en) COMPOUNDS AND THERAPEUTIC COMPOSITIONS FOR THE TREATMENT OF SOCIAL DISORDERS AND ADDICTION-RELATED DISORDERS
DK3526207T3 (da) Heterocykliske forbindelser med aktivitet som modulatorer af muscarine m1- og/eller m4-receptorer i behandling af cns-sygdomme og smerter
DK3151851T3 (da) Ornithodoros-moubata-komplement-inhibitor til anvendelse i behandlingen af komplement-medierede sygdomme hos patienter med c5-polymorfisme
DK3153511T3 (da) 2-acylaminothiazolderivat til anvendelse i forebyggelsen eller behandlingen af blære- og urinvejssygdomme
HUE060322T2 (hu) Belélegezhetõ készítmények tüdõbetegségek kezelése során történõ alkalmazásra
DK3452465T3 (da) Substituerede 2,4-diaminoquinolinderivater til anvendelse til behandling af proliferative sygdomme
DK3937948T3 (da) Phytoecdysoner og derivater deraf til anvendelse i behandlingen af neuromuskulære sygdomme
DK3515409T3 (da) Kompleks og sammensætninger til behandling af oftalmologiske og dermatologiske sygdomme
EA201491522A1 (ru) Способы лечения нарушения походки и/или равновесия у пациентов с рассеянным склерозом с использованием аминопиридина
DK3842436T3 (da) Farmaceutisk sammensætning omfattende imidazopyridin- eller imidazotriazinderivater til anvendelse i behandlingen af skizofreni
DK3731815T3 (da) Tørpulver-ketaminsammensætning til anvendelse i behandlingen af depression via pulmonal indgivelse
GB2569682B (en) Topical composition for use in the treatment of burns