SG11201810611YA - Coumarin compounds and their uses as fluorescent labels - Google Patents
Coumarin compounds and their uses as fluorescent labelsInfo
- Publication number
- SG11201810611YA SG11201810611YA SG11201810611YA SG11201810611YA SG11201810611YA SG 11201810611Y A SG11201810611Y A SG 11201810611YA SG 11201810611Y A SG11201810611Y A SG 11201810611YA SG 11201810611Y A SG11201810611Y A SG 11201810611YA SG 11201810611Y A SG11201810611Y A SG 11201810611YA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- rule
- chesterford
- fluorescent labels
- pct
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems
- C07D491/147—Ortho-condensed systems the condensed system containing one ring with oxygen as ring hetero atom and two rings with nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B57/00—Other synthetic dyes of known constitution
- C09B57/02—Coumarine dyes
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
- C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1018—Heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/107—Nucleic acid detection characterized by the use of physical, structural and functional properties fluorescence
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pyrane Compounds (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662438006P | 2016-12-22 | 2016-12-22 | |
PCT/EP2017/083128 WO2018114710A1 (en) | 2016-12-22 | 2017-12-15 | Coumarin compounds and their uses as fluorescent labels |
Publications (1)
Publication Number | Publication Date |
---|---|
SG11201810611YA true SG11201810611YA (en) | 2018-12-28 |
Family
ID=60765630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG11201810611YA SG11201810611YA (en) | 2016-12-22 | 2017-12-15 | Coumarin compounds and their uses as fluorescent labels |
Country Status (12)
Country | Link |
---|---|
US (4) | US10214768B2 (zh) |
EP (2) | EP4257596A3 (zh) |
JP (1) | JP2020504074A (zh) |
KR (1) | KR102512190B1 (zh) |
CN (1) | CN109476674B (zh) |
AU (2) | AU2017379315B2 (zh) |
CA (1) | CA3025880C (zh) |
ES (1) | ES2954284T3 (zh) |
IL (1) | IL263358B (zh) |
NZ (1) | NZ778462A (zh) |
SG (1) | SG11201810611YA (zh) |
WO (1) | WO2018114710A1 (zh) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN109476674B (zh) * | 2016-12-22 | 2021-12-10 | 伊鲁米纳剑桥有限公司 | 香豆素化合物及其作为荧光标记物的用途 |
RS65335B1 (sr) | 2018-10-05 | 2024-04-30 | Annapurna Bio Inc | Jedinjenja i kompozicije za lečenje stanja povezanih sa aktivnošću receptora apj |
WO2020178231A1 (en) * | 2019-03-01 | 2020-09-10 | Illumina, Inc. | Multiplexed fluorescent detection of analytes |
NL2023327B1 (en) * | 2019-03-01 | 2020-09-17 | Illumina Inc | Multiplexed fluorescent detection of analytes |
CN112794857B (zh) * | 2019-11-13 | 2023-09-19 | 湖南超亟检测技术有限责任公司 | 一种可用于亚铁离子检测的荧光探针及制备和应用 |
CN114829369A (zh) | 2019-11-27 | 2022-07-29 | 伊鲁米纳剑桥有限公司 | 含环辛四烯的染料和组合物 |
US20220195517A1 (en) * | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Long stokes shift chromenoquinoline dyes and uses in sequencing applications |
US20220195196A1 (en) * | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Alkylpyridinium coumarin dyes and uses in sequencing applications |
US20220195516A1 (en) | 2020-12-17 | 2022-06-23 | Illumina Cambridge Limited | Methods, systems and compositions for nucleic acid sequencing |
US20220195518A1 (en) | 2020-12-22 | 2022-06-23 | Illumina Cambridge Limited | Methods and compositions for nucleic acid sequencing |
CN114671843B (zh) * | 2020-12-24 | 2023-07-04 | 郑州思昆生物工程有限公司 | 一种荧光化合物、荧光修饰核苷酸、试剂盒 |
JP2024519372A (ja) | 2021-05-20 | 2024-05-10 | イルミナ インコーポレイテッド | 合成によって配列決定するための組成物及び方法 |
AU2023246676A1 (en) | 2022-03-28 | 2024-01-18 | Illumina Inc. | Labeled avidin and methods for sequencing |
WO2023192163A1 (en) * | 2022-03-29 | 2023-10-05 | Illumina Cambridge Limited | Systems and methods of sequencing polynucleotides |
WO2023186982A1 (en) | 2022-03-31 | 2023-10-05 | Illumina, Inc. | Compositions and methods for improving sequencing signals |
AU2023244351A1 (en) | 2022-03-31 | 2024-01-18 | Illumina, Inc. | Nucleosides and nucleotides with 3' vinyl blocking group useful in sequencing by synthesis |
WO2023232829A1 (en) | 2022-05-31 | 2023-12-07 | Illumina, Inc | Compositions and methods for nucleic acid sequencing |
US20240140939A1 (en) | 2022-09-30 | 2024-05-02 | Illumina Cambridge Limited | Compositions and methods for reducing photo damage during sequencing |
Family Cites Families (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2126811A1 (en) * | 1971-05-29 | 1972-12-14 | Basf Ag | Fluorescent pigments dyes - of the coumarin series for synthetic fibres and plastics |
US5302509A (en) | 1989-08-14 | 1994-04-12 | Beckman Instruments, Inc. | Method for sequencing polynucleotides |
JPH0743896A (ja) * | 1993-07-28 | 1995-02-14 | Toyobo Co Ltd | 光重合性組成物 |
US5846719A (en) | 1994-10-13 | 1998-12-08 | Lynx Therapeutics, Inc. | Oligonucleotide tags for sorting and identification |
EP2327797B1 (en) | 1997-04-01 | 2015-11-25 | Illumina Cambridge Limited | Method of nucleic acid sequencing |
US6465178B2 (en) | 1997-09-30 | 2002-10-15 | Surmodics, Inc. | Target molecule attachment to surfaces |
US6485944B1 (en) | 1997-10-10 | 2002-11-26 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
US6093518A (en) * | 1998-02-09 | 2000-07-25 | Kansai Paint Co., Ltd. | Visible laser-curable composition |
GB0002310D0 (en) | 2000-02-01 | 2000-03-22 | Solexa Ltd | Polynucleotide sequencing |
JP2002521064A (ja) | 1998-07-30 | 2002-07-16 | ソレックサ リミテッド | アレイ生体分子およびシークエンシングにおけるその使用 |
AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
US6391937B1 (en) | 1998-11-25 | 2002-05-21 | Motorola, Inc. | Polyacrylamide hydrogels and hydrogel arrays made from polyacrylamide reactive prepolymers |
US6372813B1 (en) | 1999-06-25 | 2002-04-16 | Motorola | Methods and compositions for attachment of biomolecules to solid supports, hydrogels, and hydrogel arrays |
US6664061B2 (en) | 1999-06-25 | 2003-12-16 | Amersham Biosciences Ab | Use and evaluation of a [2+2] photoaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix |
WO2002012566A2 (en) | 2000-08-09 | 2002-02-14 | Motorola, Inc. | The use and evaluation of a [2+2] photocycloaddition in immobilization of oligonucleotides on a three-dimensional hydrogel matrix |
JP4837174B2 (ja) * | 2001-02-02 | 2011-12-14 | 株式会社林原生物化学研究所 | クマリン誘導体およびその製造方法、それを利用した発光剤、発光素子 |
DE10160524A1 (de) * | 2001-12-05 | 2003-06-26 | Dyomics Gmbh | Neue Fluoreszenzmarker mit großem Stokes-Shift |
GB0205281D0 (en) * | 2002-03-06 | 2002-04-17 | Novartis Ag | Organic compounds |
SI3587433T1 (sl) | 2002-08-23 | 2020-08-31 | Illumina Cambridge Limited | Modificirani nukleotidi |
EP2119722B1 (en) | 2002-08-23 | 2016-10-26 | Illumina Cambridge Limited | Labelled nucleotides |
DE10356130A1 (de) * | 2003-11-28 | 2005-06-23 | Dyomics Gmbh | Neue Polymethinfarbstoffe auf Cumarin-Basis mit einstellbarem Stokes-Shift |
US7563907B2 (en) * | 2002-12-05 | 2009-07-21 | Dyomics Gmbh | Compounds based on polymethines |
US6727362B1 (en) * | 2003-06-19 | 2004-04-27 | Labeltek Inc. | Coumarin derivatives and an electroluminescent (EL) device using the coumarin derivatives |
GB0321306D0 (en) | 2003-09-11 | 2003-10-15 | Solexa Ltd | Modified polymerases for improved incorporation of nucleotide analogues |
GB0326073D0 (en) | 2003-11-07 | 2003-12-10 | Solexa Ltd | Improvements in or relating to polynucleotide arrays |
WO2005065814A1 (en) | 2004-01-07 | 2005-07-21 | Solexa Limited | Modified molecular arrays |
US20080194522A1 (en) * | 2004-08-25 | 2008-08-14 | Gong Chen | Development of Fluorogenic Substrates For Monoamine Oxidases (Mao-A and Mao-B) |
JP4990886B2 (ja) | 2005-05-10 | 2012-08-01 | ソレックサ リミテッド | 改良ポリメラーゼ |
GB0517097D0 (en) | 2005-08-19 | 2005-09-28 | Solexa Ltd | Modified nucleosides and nucleotides and uses thereof |
USRE49362E1 (en) | 2006-05-18 | 2023-01-10 | Illumina Cambridge Limited | Dye compounds and the use of their labelled conjugates |
DE102008018132A1 (de) * | 2008-04-09 | 2009-10-15 | Henkel Ag & Co. Kgaa | Kationische Direktzieher und Mittel zum Färben von keratinhaltigen Fasern |
EP2370596B1 (en) * | 2008-12-01 | 2017-06-07 | QIAGEN GmbH | Novel combination of fluorescent dyes for the detection of nucleic acids |
JP2010168369A (ja) * | 2008-12-25 | 2010-08-05 | Canon Inc | 眼内組織用標識組成物、眼内組織の標識方法及びスクリーニング方法 |
CN101851505B (zh) * | 2010-06-09 | 2013-02-27 | 深圳丹邦投资集团有限公司 | 一种香豆素类有机电致荧光材料及其合成方法 |
EP2705159B1 (en) * | 2011-05-06 | 2018-03-21 | Qiagen GmbH | Methods for sequencing, amplification and detection of nucleic acids comprising internally labelled primer |
CA3104322C (en) | 2011-09-23 | 2023-06-13 | Illumina, Inc. | Methods and compositions for nucleic acid sequencing |
WO2013056720A1 (en) | 2011-10-18 | 2013-04-25 | Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V. | Fluorescent dyes with phosphorylated hydroxymethyl groups and their use in light microscopy and imaging techniques |
JP6174881B2 (ja) * | 2012-04-04 | 2017-08-02 | 住友化学株式会社 | 着色硬化性樹脂組成物 |
US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
WO2014135223A1 (en) * | 2013-03-08 | 2014-09-12 | Illumina Cambridge Ltd | Rhodamine compounds and their use as fluorescent labels |
EP3388442A1 (en) | 2013-03-15 | 2018-10-17 | Illumina Cambridge Limited | Modified nucleosides or nucleotides |
CN105218538B (zh) * | 2015-09-24 | 2017-04-26 | 四川大学 | 取代的香豆素‑吡啶衍生物及其制备方法和用途 |
CN109476674B (zh) * | 2016-12-22 | 2021-12-10 | 伊鲁米纳剑桥有限公司 | 香豆素化合物及其作为荧光标记物的用途 |
-
2017
- 2017-12-15 CN CN201780042084.7A patent/CN109476674B/zh active Active
- 2017-12-15 EP EP23182481.4A patent/EP4257596A3/en active Pending
- 2017-12-15 SG SG11201810611YA patent/SG11201810611YA/en unknown
- 2017-12-15 CA CA3025880A patent/CA3025880C/en active Active
- 2017-12-15 WO PCT/EP2017/083128 patent/WO2018114710A1/en active Search and Examination
- 2017-12-15 AU AU2017379315A patent/AU2017379315B2/en active Active
- 2017-12-15 ES ES17817742T patent/ES2954284T3/es active Active
- 2017-12-15 EP EP17817742.4A patent/EP3559004B1/en active Active
- 2017-12-15 KR KR1020187037384A patent/KR102512190B1/ko active IP Right Grant
- 2017-12-15 JP JP2018566875A patent/JP2020504074A/ja active Pending
- 2017-12-15 NZ NZ778462A patent/NZ778462A/en unknown
- 2017-12-21 US US15/851,014 patent/US10214768B2/en active Active
-
2018
- 2018-11-28 IL IL263358A patent/IL263358B/en active IP Right Grant
-
2019
- 2019-02-22 US US16/282,783 patent/US10533211B2/en active Active
-
2020
- 2020-01-09 US US16/738,560 patent/US10907196B2/en active Active
-
2021
- 2021-01-29 US US17/162,606 patent/US11371078B2/en active Active
-
2022
- 2022-06-14 AU AU2022204153A patent/AU2022204153B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
EP4257596A3 (en) | 2023-12-06 |
EP3559004B1 (en) | 2023-07-05 |
ES2954284T3 (es) | 2023-11-21 |
CN109476674B (zh) | 2021-12-10 |
US20180201981A1 (en) | 2018-07-19 |
CN109476674A (zh) | 2019-03-15 |
US10533211B2 (en) | 2020-01-14 |
AU2022204153A1 (en) | 2022-06-30 |
EP4257596A2 (en) | 2023-10-11 |
IL263358A (en) | 2018-12-31 |
US20200216882A1 (en) | 2020-07-09 |
AU2022204153B2 (en) | 2024-01-18 |
CA3025880C (en) | 2020-01-28 |
EP3559004A1 (en) | 2019-10-30 |
US20210155977A1 (en) | 2021-05-27 |
IL263358B (en) | 2020-06-30 |
KR20190095873A (ko) | 2019-08-16 |
AU2017379315A1 (en) | 2018-12-13 |
US11371078B2 (en) | 2022-06-28 |
NZ778462A (en) | 2024-02-23 |
US20190185918A1 (en) | 2019-06-20 |
US10214768B2 (en) | 2019-02-26 |
KR102512190B1 (ko) | 2023-03-21 |
CA3025880A1 (en) | 2018-06-28 |
NZ748730A (en) | 2021-08-27 |
JP2020504074A (ja) | 2020-02-06 |
WO2018114710A1 (en) | 2018-06-28 |
US10907196B2 (en) | 2021-02-02 |
AU2017379315B2 (en) | 2022-04-14 |
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