SG11201809687TA - Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors - Google Patents

Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors

Info

Publication number
SG11201809687TA
SG11201809687TA SG11201809687TA SG11201809687TA SG11201809687TA SG 11201809687T A SG11201809687T A SG 11201809687TA SG 11201809687T A SG11201809687T A SG 11201809687TA SG 11201809687T A SG11201809687T A SG 11201809687TA SG 11201809687T A SG11201809687T A SG 11201809687TA
Authority
SG
Singapore
Prior art keywords
rhein
international
gmbh
ingelheim
boehringer ingelheim
Prior art date
Application number
SG11201809687TA
Other languages
English (en)
Inventor
Andreas Blum
Cédrickx Godbout
Joerg Hehn
Stefan Peters
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of SG11201809687TA publication Critical patent/SG11201809687TA/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201809687TA 2016-05-12 2017-05-08 Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors SG11201809687TA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16169356 2016-05-12
PCT/EP2017/060890 WO2017194453A1 (en) 2016-05-12 2017-05-08 Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors

Publications (1)

Publication Number Publication Date
SG11201809687TA true SG11201809687TA (en) 2018-11-29

Family

ID=55967162

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201809687TA SG11201809687TA (en) 2016-05-12 2017-05-08 Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors

Country Status (32)

Country Link
US (1) US9926292B2 (sr)
EP (1) EP3455216B1 (sr)
JP (1) JP6639702B2 (sr)
KR (1) KR20190003995A (sr)
CN (1) CN109153664B (sr)
AR (1) AR108462A1 (sr)
AU (1) AU2017262707B2 (sr)
CA (1) CA3023805A1 (sr)
CL (1) CL2018003158A1 (sr)
CO (1) CO2018012020A2 (sr)
CY (1) CY1123744T1 (sr)
DK (1) DK3455216T3 (sr)
EA (1) EA037188B1 (sr)
ES (1) ES2844926T3 (sr)
HR (1) HRP20202078T1 (sr)
HU (1) HUE053312T2 (sr)
IL (1) IL262662B (sr)
JO (1) JOP20170115B1 (sr)
LT (1) LT3455216T (sr)
MA (1) MA44965B1 (sr)
MX (1) MX2018013701A (sr)
PE (1) PE20190151A1 (sr)
PH (1) PH12018502376A1 (sr)
PL (1) PL3455216T3 (sr)
PT (1) PT3455216T (sr)
RS (1) RS61256B1 (sr)
SA (1) SA518400393B1 (sr)
SG (1) SG11201809687TA (sr)
SI (1) SI3455216T1 (sr)
TW (1) TWI746551B (sr)
UA (1) UA121930C2 (sr)
WO (1) WO2017194453A1 (sr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019254371A1 (en) 2018-04-17 2020-10-08 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
WO2020083264A1 (zh) * 2018-10-22 2020-04-30 广东东阳光药业有限公司 胍类衍生物及其用途
KR20210084537A (ko) * 2018-10-29 2021-07-07 베링거 인겔하임 인터내셔날 게엠베하 피리디닐 설폰아미드 유도체, 약제학적 조성물 및 이의 용도
WO2021083209A1 (en) 2019-10-29 2021-05-06 Eccogene (Shanghai) Co., Ltd. Ssao inhibitors and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19518073A1 (de) * 1995-05-17 1996-11-21 Hoechst Ag Substituierte Benzyloxycarbonylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
CA2536954C (en) * 2003-08-29 2012-11-27 Exelixis, Inc. C-kit modulators and methods of use
CA2575411A1 (en) * 2004-07-27 2006-02-02 Astellas Pharma Inc. Thiazole derivatives having vap-1 inhibitory activity
PL2479165T3 (pl) * 2009-09-16 2018-05-30 Astellas Pharma Inc. Związek glicynowy
ES2628850T3 (es) * 2011-03-15 2017-08-04 Astellas Pharma Inc. Compuesto de guanidina
JP6809464B2 (ja) 2015-08-06 2021-01-06 宇部興産株式会社 置換グアニジン誘導体

Also Published As

Publication number Publication date
PE20190151A1 (es) 2019-01-22
CO2018012020A2 (es) 2018-11-13
DK3455216T3 (da) 2021-01-18
JOP20170115B1 (ar) 2021-08-17
RS61256B1 (sr) 2021-01-29
PT3455216T (pt) 2021-01-18
AU2017262707B2 (en) 2020-11-19
EP3455216A1 (en) 2019-03-20
KR20190003995A (ko) 2019-01-10
US20170327483A1 (en) 2017-11-16
MX2018013701A (es) 2019-05-02
US9926292B2 (en) 2018-03-27
CA3023805A1 (en) 2017-11-16
JP6639702B2 (ja) 2020-02-05
CN109153664B (zh) 2021-07-16
PH12018502376B1 (en) 2019-04-08
SI3455216T1 (sl) 2021-02-26
UA121930C2 (uk) 2020-08-10
EA201892539A1 (ru) 2019-06-28
CL2018003158A1 (es) 2019-01-18
HRP20202078T1 (hr) 2021-02-19
NZ746586A (en) 2021-08-27
TWI746551B (zh) 2021-11-21
EA037188B1 (ru) 2021-02-17
IL262662B (en) 2021-07-29
AU2017262707A1 (en) 2018-10-11
CN109153664A (zh) 2019-01-04
MA44965B1 (fr) 2021-02-26
AR108462A1 (es) 2018-08-22
EP3455216B1 (en) 2020-11-04
WO2017194453A1 (en) 2017-11-16
MA44965A (fr) 2019-03-20
TW201805278A (zh) 2018-02-16
IL262662A (en) 2018-12-31
ES2844926T3 (es) 2021-07-23
PH12018502376A1 (en) 2019-04-08
JP2019519495A (ja) 2019-07-11
CY1123744T1 (el) 2022-05-27
PL3455216T3 (pl) 2021-05-17
SA518400393B1 (ar) 2021-09-08
HUE053312T2 (hu) 2021-07-28
LT3455216T (lt) 2021-01-11

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