SG11201809483UA - Production of steviol glycosides in recombinant hosts - Google Patents
Production of steviol glycosides in recombinant hostsInfo
- Publication number
- SG11201809483UA SG11201809483UA SG11201809483UA SG11201809483UA SG11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA SG 11201809483U A SG11201809483U A SG 11201809483UA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- steviol
- copenhagen
- pct
- glycosides
- Prior art date
Links
- 239000004383 Steviol glycoside Substances 0.000 title abstract 4
- 229930182488 steviol glycoside Natural products 0.000 title abstract 4
- 150000008144 steviol glycosides Chemical class 0.000 title abstract 4
- 235000019411 steviol glycoside Nutrition 0.000 title abstract 3
- 235000019202 steviosides Nutrition 0.000 title abstract 3
- QFVOYBUQQBFCRH-UHFFFAOYSA-N Steviol Natural products C1CC2(C3)CC(=C)C3(O)CCC2C2(C)C1C(C)(C(O)=O)CCC2 QFVOYBUQQBFCRH-UHFFFAOYSA-N 0.000 abstract 3
- 229940032084 steviol Drugs 0.000 abstract 3
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002243 precursor Substances 0.000 abstract 2
- 229930182470 glycoside Natural products 0.000 abstract 1
- 150000002338 glycosides Chemical class 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- QFVOYBUQQBFCRH-VQSWZGCSSA-N steviol Chemical compound C([C@@]1(O)C(=C)C[C@@]2(C1)CC1)C[C@H]2[C@@]2(C)[C@H]1[C@](C)(C(O)=O)CCC2 QFVOYBUQQBFCRH-VQSWZGCSSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662337213P | 2016-05-16 | 2016-05-16 | |
| PCT/EP2017/061774 WO2017198681A1 (en) | 2016-05-16 | 2017-05-16 | Production of steviol glycosides in recombinant hosts |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201809483UA true SG11201809483UA (en) | 2018-11-29 |
Family
ID=58739035
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201809483UA SG11201809483UA (en) | 2016-05-16 | 2017-05-16 | Production of steviol glycosides in recombinant hosts |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20190144907A1 (https=) |
| EP (1) | EP3458598A1 (https=) |
| JP (1) | JP2019519212A (https=) |
| CN (1) | CN109477128A (https=) |
| AU (1) | AU2017267214A1 (https=) |
| BR (1) | BR112018073662A2 (https=) |
| CA (1) | CA3023399A1 (https=) |
| SG (1) | SG11201809483UA (https=) |
| WO (1) | WO2017198681A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3497222T (pt) | 2016-08-12 | 2022-02-09 | Amyris Inc | Glicosiltransferase dependente de udp para produção de eficácia elevada de rebaudiosídeos |
| BR112019007504B1 (pt) * | 2016-10-14 | 2023-05-09 | Conagen Inc | Método de preparação de uma composição de glicosídeo de esteviol |
| BR112020009838A2 (pt) * | 2017-12-05 | 2020-11-17 | Evolva Sa | produção de glicosídeos de esteviol em hospedeiros recombinantes |
| CA3101651A1 (en) * | 2018-06-08 | 2019-12-12 | Purecircle Usa Inc. | High-purity steviol glycosides |
| EP3877519B1 (en) | 2018-11-09 | 2026-03-11 | Ginkgo Bioworks, Inc. | Biosynthesis of mogrosides |
| CN110564658B (zh) * | 2019-09-06 | 2021-08-17 | 广西大学 | 一株大肠杆菌工程菌及其全细胞催化生产甜菊醇的方法 |
| CN112760301B (zh) * | 2019-11-01 | 2023-01-17 | 中国科学院天津工业生物技术研究所 | 一种催化活性提高的糖基转移酶突变体及其应用 |
| CN111235124B (zh) * | 2020-01-19 | 2023-04-07 | 云南农业大学 | 珠子参糖基转移酶UGTPjm2及其在制备竹节参皂苷IVa上的应用 |
| US11396646B2 (en) | 2020-05-29 | 2022-07-26 | QTG Development, Inc. | Steviol glycosyltransferases and genes encoding the same |
| CN113308447B (zh) * | 2021-05-31 | 2022-09-30 | 西南大学 | 拟南芥ugt74f2在催化苯乳酸合成苯乳酰葡萄糖中的应用 |
| CN114736887A (zh) * | 2022-03-25 | 2022-07-12 | 上海威高医疗技术发展有限公司 | 羧酸酯酶的用途 |
| WO2025238041A1 (en) * | 2024-05-16 | 2025-11-20 | Evonik Operations Gmbh | A novel rhamnolipid and glucolipid |
| CN120758477B (zh) * | 2025-09-10 | 2025-11-18 | 山东三元生物科技股份有限公司 | 一种糖基转移酶突变体及其在合成莱鲍迪苷m中的应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009034080A (ja) * | 2007-08-03 | 2009-02-19 | Sanei Gen Ffi Inc | 新規糖転移酵素、及びそれを利用した配糖体の製造 |
| EP2575432B1 (en) * | 2010-06-02 | 2019-08-14 | Evolva, Inc. | Recombinant production of steviol glycosides |
| CA3128532A1 (en) * | 2011-08-08 | 2013-02-14 | Evolva Sa | Recombinant production of steviol glycosides |
| BR112014012543A2 (pt) * | 2011-11-23 | 2017-06-13 | Evolva Sa | métodos e materiais para síntese enzimática de compostos de mogrosídeo |
| EP2929043A1 (en) * | 2012-12-04 | 2015-10-14 | Evolva SA | Methods and materials for biosynthesis of mogroside compounds |
| MY199452A (en) * | 2013-02-06 | 2023-10-30 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| US20160215306A1 (en) * | 2013-08-30 | 2016-07-28 | Evolva Sa | Method for producing modified resveratrol |
| SG10201807693YA (en) * | 2014-03-07 | 2018-10-30 | Evolva Sa | Methods for recombinant production of saffron compounds |
| CA2960693A1 (en) * | 2014-09-09 | 2016-03-17 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CN104845990A (zh) * | 2015-06-11 | 2015-08-19 | 山东大学 | 拟南芥糖基转移酶基因ugt73c7在提高植物抗病性中的应用 |
-
2017
- 2017-05-16 WO PCT/EP2017/061774 patent/WO2017198681A1/en not_active Ceased
- 2017-05-16 EP EP17724540.4A patent/EP3458598A1/en active Pending
- 2017-05-16 CA CA3023399A patent/CA3023399A1/en active Pending
- 2017-05-16 BR BR112018073662A patent/BR112018073662A2/pt not_active Application Discontinuation
- 2017-05-16 SG SG11201809483UA patent/SG11201809483UA/en unknown
- 2017-05-16 AU AU2017267214A patent/AU2017267214A1/en not_active Abandoned
- 2017-05-16 US US16/098,305 patent/US20190144907A1/en not_active Abandoned
- 2017-05-16 CN CN201780030752.4A patent/CN109477128A/zh active Pending
- 2017-05-16 JP JP2018560137A patent/JP2019519212A/ja active Pending
-
2021
- 2021-11-03 US US17/517,818 patent/US20220154234A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BR112018073662A2 (pt) | 2019-02-19 |
| US20220154234A1 (en) | 2022-05-19 |
| CA3023399A1 (en) | 2017-11-23 |
| AU2017267214A1 (en) | 2018-11-15 |
| US20190144907A1 (en) | 2019-05-16 |
| WO2017198681A1 (en) | 2017-11-23 |
| JP2019519212A (ja) | 2019-07-11 |
| CN109477128A (zh) | 2019-03-15 |
| EP3458598A1 (en) | 2019-03-27 |
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