SG11201808541VA - Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use - Google Patents

Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use

Info

Publication number
SG11201808541VA
SG11201808541VA SG11201808541VA SG11201808541VA SG11201808541VA SG 11201808541V A SG11201808541V A SG 11201808541VA SG 11201808541V A SG11201808541V A SG 11201808541VA SG 11201808541V A SG11201808541V A SG 11201808541VA SG 11201808541V A SG11201808541V A SG 11201808541VA
Authority
SG
Singapore
Prior art keywords
rivig
international
immune
proteins
ste
Prior art date
Application number
SG11201808541VA
Other languages
English (en)
Inventor
Yen-Ming Hsu
Jeng-Shin Lee
Hsiu-Ching Chang
Original Assignee
Ab biosciences inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab biosciences inc filed Critical Ab biosciences inc
Publication of SG11201808541VA publication Critical patent/SG11201808541VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/47Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70535Fc-receptors, e.g. CD16, CD32, CD64 (CD2314/705F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70575NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62DNA sequences coding for fusion proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/522CH1 domain
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • C07K2317/53Hinge
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
SG11201808541VA 2016-03-30 2017-03-29 Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use SG11201808541VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662315483P 2016-03-30 2016-03-30
PCT/US2017/024650 WO2017172853A1 (en) 2016-03-30 2017-03-29 Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use

Publications (1)

Publication Number Publication Date
SG11201808541VA true SG11201808541VA (en) 2018-10-30

Family

ID=59965144

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201808541VA SG11201808541VA (en) 2016-03-30 2017-03-29 Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use

Country Status (18)

Country Link
US (2) US11304994B2 (ru)
EP (1) EP3436484A4 (ru)
JP (1) JP7075100B2 (ru)
KR (1) KR102477536B1 (ru)
CN (1) CN109312000A (ru)
AU (1) AU2017245143B2 (ru)
BR (1) BR112018070022A2 (ru)
CA (1) CA3019530A1 (ru)
CL (1) CL2018002769A1 (ru)
CO (1) CO2018011457A2 (ru)
EA (1) EA201891999A1 (ru)
IL (1) IL261968A (ru)
MA (1) MA44517A (ru)
MX (1) MX2018011865A (ru)
SG (1) SG11201808541VA (ru)
TW (1) TWI801336B (ru)
WO (1) WO2017172853A1 (ru)
ZA (1) ZA201806767B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112004550A (zh) 2017-12-14 2020-11-27 康诺贝林伦瑙有限公司 用于治疗视神经脊髓炎的重组IgG Fc多聚体
US20210353752A1 (en) * 2018-10-11 2021-11-18 Momenta Pharmaceuticals, Inc. Treatment with highly silylated igg compositions
AU2019360271A1 (en) * 2018-10-18 2021-04-29 Elanco Us Inc. Fc variants with altered binding to neonatal Fc receptor (FcRn) for veterinary use
CN109793894A (zh) * 2019-04-03 2019-05-24 长春西诺生物科技有限公司 犬免疫球蛋白在制备犬溶血性贫血药物中的应用
JP2022547692A (ja) 2019-09-13 2022-11-15 ツェー・エス・エル・ベーリング・レングナウ・アクチエンゲゼルシャフト 免疫複合体介在性腎臓障害の処置のための組み換えIgG Fc多量体
CN112899301B (zh) * 2021-01-29 2023-04-11 中国热带农业科学院热带生物技术研究所 一种木薯普通花叶病毒诱导的基因沉默系统及其应用
CN115724988B (zh) * 2021-08-26 2023-11-17 瑅安生物医药(杭州)有限公司 一种接近天然分子的多肽融合分子

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1106846C (zh) * 1997-08-21 2003-04-30 宝酒造株式会社 抗癌症剂
DE19963859A1 (de) 1999-12-30 2001-07-12 Apotech Res & Dev Ltd Bi- oder Oligomer eines Di-, Tri-, Quattro- oder Pentamers von rekombinanten Fusionsproteinen
GB0015426D0 (en) 2000-06-24 2000-08-16 Univ Southampton Method for generating soluble highly multimeric proteins
CA2437958C (en) 2001-03-09 2018-10-30 University Of Chicago Polymeric immunoglobulin fusion proteins that target low-affinity fc.gamma.receptors
US7279329B2 (en) * 2005-10-17 2007-10-09 Industrial Technology Research Institute Expression system for producing collagen
US20070264687A1 (en) 2005-12-15 2007-11-15 Min-Yuan Chou Recombinant triplex scaffold-based polypeptides
GB0614780D0 (en) 2006-07-25 2006-09-06 Ucb Sa Biological products
EP2144930A1 (en) 2007-04-18 2010-01-20 ZymoGenetics, Inc. Single chain fc, methods of making and methods of treatment
NZ581395A (en) 2007-05-14 2012-08-31 Biogen Idec Inc Single-chain fc (scfc) regions, binding polypeptides comprising same, and methods related thereto
EP2641913B1 (en) * 2007-06-01 2018-04-18 University of Maryland, Baltimore Immunoglobulin constant region Fc receptor binding agents
WO2010065578A2 (en) 2008-12-04 2010-06-10 Leukosight Inc. POLYPEPTIDES COMPRISING Fc FRAGMENTS OF IMMUNOGLOBULIN G (IgG) AND METHODS OF USING THE SAME
TWI588157B (zh) 2010-07-28 2017-06-21 吉林尼克公司 產生依序多聚體化免疫球蛋白fc組合物之天然人類蛋白質片段之融合蛋白
EP2561888A1 (en) 2011-08-23 2013-02-27 Deutsches Krebsforschungszentrum Protein comprising NC-1 for treating angiogenesis-related diseases
TWI476001B (zh) 2011-12-26 2015-03-11 Ind Tech Res Inst 三倍體Fc融合蛋白及其用途
AU2013295647B2 (en) * 2012-07-26 2018-02-08 The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Multimeric fusion protein vaccine and immunotherapeutic
MX2015002269A (es) 2012-08-20 2015-07-06 Gliknik Inc Moleculas con actividad de union al antigeno y al receptor fc gamma polivalente.
EP2908914B1 (en) 2012-10-17 2018-04-18 Liverpool School of Tropical Medicine Immunomodulatory proteins
HUE060464T2 (hu) 2013-03-13 2023-03-28 Genzyme Corp PDGF- és VEGF-kötõrészeket tartalmazó fúziós fehérjék és eljárások azok alkalmazására
US20150038682A1 (en) 2013-08-02 2015-02-05 Jn Biosciences Llc Antibodies or fusion proteins multimerized via homomultimerizing peptide
BR112016023948A2 (pt) 2014-04-16 2018-01-30 Ucb Biopharma Sprl proteínas fc multiméricas
CN108289928A (zh) 2015-08-06 2018-07-17 哈佛大学校长及研究员协会 改进的微生物-结合分子和其用途

Also Published As

Publication number Publication date
AU2017245143A1 (en) 2018-10-18
US11801286B2 (en) 2023-10-31
EP3436484A4 (en) 2019-12-04
CN109312000A (zh) 2019-02-05
BR112018070022A2 (pt) 2019-02-05
CA3019530A1 (en) 2017-10-05
WO2017172853A1 (en) 2017-10-05
JP7075100B2 (ja) 2022-05-25
MX2018011865A (es) 2019-03-28
TWI801336B (zh) 2023-05-11
EA201891999A1 (ru) 2019-08-30
TW201741335A (zh) 2017-12-01
JP2019513024A (ja) 2019-05-23
US20220233658A1 (en) 2022-07-28
MA44517A (fr) 2019-02-06
KR20180132731A (ko) 2018-12-12
CL2018002769A1 (es) 2018-12-28
US11304994B2 (en) 2022-04-19
EP3436484A1 (en) 2019-02-06
KR102477536B1 (ko) 2022-12-13
CO2018011457A2 (es) 2019-02-08
ZA201806767B (en) 2023-04-26
US20190111115A1 (en) 2019-04-18
IL261968A (en) 2018-10-31
AU2017245143B2 (en) 2024-01-11

Similar Documents

Publication Publication Date Title
SG11201808541VA (en) Recombinant intravenous immunoglobulin (rivig) compositions and methods for their production and use
SG11201907867TA (en) Use of anti-ctla-4 antibodies with enhanced adcc to enhance immune response to a vaccine
SG11201906297QA (en) Nucleic acids encoding crispr-associated proteins and uses thereof
SG11201809879WA (en) Novel antibodies specifically binding to zika virus epitopes and uses thereof
SG11201908540PA (en) Stable antibody formulation
SG11201809700YA (en) Gdf15 fusion proteins and uses thereof
SG11201900955VA (en) T cell receptors and immune therapy using the same
SG11201909646TA (en) Trem2 antigen binding proteins and uses thereof
SG11201810697QA (en) Chimeric antigen receptor and car-t cells that bind bcma
SG11201807590SA (en) Transfected t-cells and t-cell receptors for use in immunotherapy against cancers
SG11201803956UA (en) Anti-dr5 antibodies and methods of use thereof
SG11201810420YA (en) Antibodies to alpha-synuclein and uses thereof
SG11201906264YA (en) Improved serum albumin binders
SG11201803975SA (en) Improved tnf binders
SG11201408095XA (en) Fibroblast growth factor 21 proteins
SG11201906341XA (en) Improved serum albumin binders
SG11201900745VA (en) Substituted thiazolo-pyridine compounds as malt1 inhibitors
SG11201908919XA (en) Combination therapies targeting pd-1, tim-3, and lag-3
SG11201806121PA (en) Ror2 antibody compositions and related methods
SG11201910134SA (en) Stable formulations of anti-ctla4 antibodies alone and in combination with programmed death receptor 1 (pd-1) antibodies and methods of use thereof
SG11201407580YA (en) Composition comprising two antibodies engineered to have reduced and increased effector function
SG11201408780XA (en) Optimization of antibodies that bind lymphocyte activation gene-3 (lag-3), and uses thereof
SG11201811737SA (en) Novel fatty acid modified urocortin-2 analogs for the treatment of diabetes and chronic kidney disease
SG11201903693QA (en) Polypeptide variants and uses thereof
SG11201907646YA (en) Proteins binding her2, nkg2d and cd16