SG11201807404XA - Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease - Google Patents
Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's diseaseInfo
- Publication number
- SG11201807404XA SG11201807404XA SG11201807404XA SG11201807404XA SG11201807404XA SG 11201807404X A SG11201807404X A SG 11201807404XA SG 11201807404X A SG11201807404X A SG 11201807404XA SG 11201807404X A SG11201807404X A SG 11201807404XA SG 11201807404X A SG11201807404X A SG 11201807404XA
- Authority
- SG
- Singapore
- Prior art keywords
- international
- madrid
- crohn
- disease
- stem cells
- Prior art date
Links
- 208000011231 Crohn disease Diseases 0.000 title abstract 3
- 210000000130 stem cell Anatomy 0.000 title abstract 3
- 210000000577 adipose tissue Anatomy 0.000 title abstract 2
- 206010002156 anal fistula Diseases 0.000 title abstract 2
- 206010016717 Fistula Diseases 0.000 abstract 1
- 230000000735 allogeneic effect Effects 0.000 abstract 1
- 230000003890 fistula Effects 0.000 abstract 1
- 230000008520 organization Effects 0.000 abstract 1
- 102220240796 rs553605556 Human genes 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0667—Adipose-derived stem cells [ADSC]; Adipose stromal stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/35—Fat tissue; Adipocytes; Stromal cells; Connective tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0653—Adipocytes; Adipose tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Developmental Biology & Embryology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1604304.4A GB201604304D0 (en) | 2016-03-14 | 2016-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| PCT/IB2017/051468 WO2017158509A1 (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201807404XA true SG11201807404XA (en) | 2018-09-27 |
Family
ID=55952284
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202008992YA SG10202008992YA (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| SG11201807404XA SG11201807404XA (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10202008992YA SG10202008992YA (en) | 2016-03-14 | 2017-03-14 | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
Country Status (26)
| Country | Link |
|---|---|
| US (3) | US10357518B2 (pt) |
| EP (2) | EP3219321B1 (pt) |
| JP (2) | JP6931656B2 (pt) |
| KR (1) | KR102277789B1 (pt) |
| CN (2) | CN108883135B (pt) |
| AU (1) | AU2017232718B2 (pt) |
| BE (1) | BE1024781B1 (pt) |
| CA (1) | CA3017694C (pt) |
| DE (1) | DE102017002458B4 (pt) |
| DK (1) | DK3219321T3 (pt) |
| ES (2) | ES2681774B1 (pt) |
| FR (1) | FR3048614B1 (pt) |
| GB (2) | GB201604304D0 (pt) |
| HR (1) | HRP20220539T1 (pt) |
| HU (1) | HUE058739T2 (pt) |
| IL (2) | IL261730B2 (pt) |
| LT (1) | LT3219321T (pt) |
| MX (1) | MX2018010699A (pt) |
| NL (1) | NL2018512B1 (pt) |
| NO (1) | NO345415B1 (pt) |
| PL (1) | PL3219321T3 (pt) |
| RS (1) | RS63163B1 (pt) |
| RU (1) | RU2742308C2 (pt) |
| SG (2) | SG10202008992YA (pt) |
| SI (1) | SI3219321T1 (pt) |
| WO (1) | WO2017158509A1 (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
| GB201604304D0 (en) * | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
| US20210401895A1 (en) | 2017-03-30 | 2021-12-30 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with live biotherapeutics |
| EP3931307A1 (en) * | 2019-02-27 | 2022-01-05 | TiGenix, S.A.U. | Improved stem cell populations for allogeneic therapy |
| KR20220152239A (ko) * | 2020-03-11 | 2022-11-15 | 메조블라스트 인터내셔널 에스에이알엘 | 염증성 장 질환 i의 치료 방법 |
| JP2023517641A (ja) * | 2020-03-11 | 2023-04-26 | メゾブラスト・インターナショナル・エスアーエールエル | 炎症性腸疾患を治療するための方法ｉｉ |
| CN111481573A (zh) * | 2020-03-26 | 2020-08-04 | 卡替（上海）生物技术股份有限公司 | 牙髓间充质干细胞在制备克罗恩病治疗药物中的用途 |
| JP2023551479A (ja) * | 2020-11-25 | 2023-12-08 | フラッグシップ パイオニアリング， インコーポレイテッド | 脂肪生成細胞組成物及び方法 |
| WO2023230524A1 (en) * | 2022-05-25 | 2023-11-30 | Flagship Pioneering Innovations Vi, Llc | Compositions of secretory and/or catalytic cells and methods using the same |
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2016
- 2016-03-14 GB GBGB1604304.4A patent/GB201604304D0/en not_active Ceased
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2017
- 2017-03-14 NO NO20170376A patent/NO345415B1/en unknown
- 2017-03-14 US US15/458,509 patent/US10357518B2/en active Active
- 2017-03-14 RS RS20220355A patent/RS63163B1/sr unknown
- 2017-03-14 BE BE2017/5156A patent/BE1024781B1/de active IP Right Grant
- 2017-03-14 SG SG10202008992YA patent/SG10202008992YA/en unknown
- 2017-03-14 SG SG11201807404XA patent/SG11201807404XA/en unknown
- 2017-03-14 IL IL261730A patent/IL261730B2/en unknown
- 2017-03-14 CN CN201780017154.3A patent/CN108883135B/zh active Active
- 2017-03-14 CA CA3017694A patent/CA3017694C/en active Active
- 2017-03-14 SI SI201731122T patent/SI3219321T1/sl unknown
- 2017-03-14 JP JP2018548356A patent/JP6931656B2/ja active Active
- 2017-03-14 EP EP17160932.4A patent/EP3219321B1/en active Active
- 2017-03-14 PL PL17160932T patent/PL3219321T3/pl unknown
- 2017-03-14 IL IL298107A patent/IL298107B2/en unknown
- 2017-03-14 DK DK17160932.4T patent/DK3219321T3/da active
- 2017-03-14 HR HRP20220539TT patent/HRP20220539T1/hr unknown
- 2017-03-14 WO PCT/IB2017/051468 patent/WO2017158509A1/en active Application Filing
- 2017-03-14 HU HUE17160932A patent/HUE058739T2/hu unknown
- 2017-03-14 KR KR1020187029414A patent/KR102277789B1/ko active IP Right Grant
- 2017-03-14 MX MX2018010699A patent/MX2018010699A/es unknown
- 2017-03-14 FR FR1752073A patent/FR3048614B1/fr active Active
- 2017-03-14 ES ES201700204A patent/ES2681774B1/es active Active
- 2017-03-14 AU AU2017232718A patent/AU2017232718B2/en active Active
- 2017-03-14 LT LTEP17160932.4T patent/LT3219321T/lt unknown
- 2017-03-14 EP EP22163484.3A patent/EP4074322A1/en active Pending
- 2017-03-14 NL NL2018512A patent/NL2018512B1/nl active
- 2017-03-14 RU RU2018131519A patent/RU2742308C2/ru active
- 2017-03-14 CN CN202211257331.4A patent/CN115569151A/zh active Pending
- 2017-03-14 GB GB1704065.0A patent/GB2548490B/en active Active
- 2017-03-14 ES ES17160932T patent/ES2911718T3/es active Active
- 2017-03-14 DE DE102017002458.8A patent/DE102017002458B4/de active Active
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2019
- 2019-06-25 US US16/452,321 patent/US11273182B2/en active Active
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2021
- 2021-05-17 JP JP2021083406A patent/JP2021119789A/ja active Pending
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2022
- 2022-02-14 US US17/671,479 patent/US20220249574A1/en active Pending
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